Hypothalamic lesions increase neuronal immunoreactivity for neuropeptide Y.

abstract：:Microglial and astroglial cells undergo prompt responses to peripheral motor and sensory axon injury. These responses include proliferation of microglial cells as well as hypertrophy and increased levels of glial fibrillary acidic protein around the axotomized motoneurons and in the central projection territories of p...

journal_title：Brain research bulletin

authors： Svensson M,Eriksson P,Persson JK,Molander C,Arvidsson J,Aldskogius H

更新日期：1993-01-01 00:00:00

abstract：:Morphine exposure may have a negative effect on the receptive field properties of neurons in primary visual cortex of cats. The present experiment used morphological methods in order to investigate whether chronic morphine treatment also affects dendritic characters of these neurons. According to the Sholl analysis an...

journal_title：Brain research bulletin

authors： Hu F,Li G,Liang Z,Yang Y,Zhou Y

更新日期：2008-09-30 00:00:00

abstract：:Multiple lines of investigation have explored the role of dopaminergic systems in mental depression. Chronic treatment with antidepressant drugs has been reported to alter dopaminergic neurotransmission, most notably a sensitization of behavioural responses to agonists acting at D2/D3 dopamine receptors within the nuc...

journal_title：Brain research bulletin

authors： Dhir A,Kulkarni SK

更新日期：2007-09-14 00:00:00

abstract：:Growing interest in cholinergic neuronal systems has caused a resurgence of thiocholine histochemical studies. Reports from different laboratories refer to "modified" Koelle-Friedenwald procedures for the histochemical localization of acetylcholinesterase (AChE) but the modifications are seldom specified. A glance at ...

journal_title：Brain research bulletin

authors： van Ooteghem SA,Shipley MT

更新日期：1984-05-01 00:00:00

abstract：:Gestational exposure to nicotine has been shown to interfere with biochemical markers of development of central and peripheral noradrenergic activity. The current study examines the development and function of cardiac beta-adrenergic receptors in the offspring of pregnant rats given nicotine infusions of 6 mg/kg/day f...

journal_title：Brain research bulletin

authors： Navarro HA,Mills E,Seidler FJ,Baker FE,Lappi SE,Tayyeb MI,Spencer JR,Slotkin TA

更新日期：1990-08-01 00:00:00

abstract：:The role of gamma-aminobutyric acid (GABA) in the regulation of gonadotropin hormone-releasing hormone (GnRH) release was studied using rat hypothalamic slices in vitro. Perifusion with GABA (10(-8)-10(-4) M) caused a dose-dependent increase in GnRH release. The GABAA receptor agonist isoguvacine (10(-5) M) also stimu...

journal_title：Brain research bulletin

authors： Nikolarakis KE,Loeffler JP,Almeida OF,Herz A

更新日期：1988-10-01 00:00:00

abstract：:Several studies have demonstrated alterations in the dopamine (DA) system after traumatic brain injury (TBI). Additionally, the existence of significant sex-related differences in the dopaminergic system has long been recognized. Accordingly, the purpose of the present study was to investigate whether TBI would differ...

journal_title：Brain research bulletin

authors： Xu X,Cao S,Chao H,Liu Y,Ji J

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to investigate whether the histamine H1-receptor blocker, chlorpheniramine (CPA), has a reinforcing effect in goldfish. We used a place-preference procedure in an aquarium with two chambers colored black and white. On day 1, the animals were placed in the test chamber for 10 min for habituati...

journal_title：Brain research bulletin

authors： Mattioli R,Nelson CA,Huston JP,Spieler RE

更新日期：1998-01-01 00:00:00

abstract：:The development of central serotonergic neurons has been examined immunocytochemically utilizing an antiserum to serotonin (5-HT). Cells of the B4-B9 complex are first detected early on embryonic day 13 (E13; 7 mm crown rump length, CRL) and increase rapidly in number through E15 when they appear as bilateral columns ...

journal_title：Brain research bulletin

authors： Wallace JA,Lauder JM

更新日期：1983-04-01 00:00:00

abstract：:Walker 256 carcinosarcoma cells produce subpleural pulmonary metastases when given intravenously to the Sprague-Dawley rat. The number of metastases increases when the rat is given morphine subsequent to the tumor load. The increase in the number of metastases can be blocked be pretreatment with the opiate antagonist ...

journal_title：Brain research bulletin

authors： Simon RH,Arbo TE

更新日期：1986-03-01 00:00:00

abstract：:Prior results (37) showed that morphine pretreatment reduces the escape response of the crab Chasmagnathus to a shadow passing overhead and prevents the acquisition of a long-term habituation. These results were explained by a reduction in the danger signalled by the stimulus, and to test this hypothesis methods other...

journal_title：Brain research bulletin

authors： Tomsic D,Maldonado H,Rakitin A

更新日期：1991-05-01 00:00:00

abstract：:The topographical distribution of cholinergic cell bodies has been studied in the rat brain and spinal cord by choline acetyltransferase (ChAT)-immunohistochemistry and acetylcholinesterase (AChE)-pharmacohistochemistry using diisopropylfluorophosphate (DFP). The ChAT-containing cells and the cells that stained intens...

journal_title：Brain research bulletin

authors： Satoh K,Armstrong DM,Fibiger HC

更新日期：1983-12-01 00:00:00

abstract：:Stimulation of the dorsal frontal cortex (area 10, FCtx) evoked two negative waves with short latencies (N1 and N2) followed by a large, longlasting positive wave (P) in the ventromedial nucleus (VMH) as well as in the more dorsal structures in the hypothalamus and the ventral thalamus. Since the N1 followed high freq...

journal_title：Brain research bulletin

authors： Ohta M,Oomura Y

更新日期：1979-03-01 00:00:00

abstract：:Using immunohistochemistry for serotonin (5-HT) after administration of 5-hydroxytryptophan (5-HTP), we have demonstrated the existence of a particular group of 5-HT accumulating neurons in the posterior hypothalamus of the rat and cat. This cluster of neurons, which we termed "5-HT immunoreactive (IR) posterior hypot...

journal_title：Brain research bulletin

authors： Sakumoto T,Sakai K,Jouvet M,Kimura H,Maeda T

更新日期：1984-06-01 00:00:00

abstract：:Administration of methionine enkephalin (ICV) to rats for 5 days resulted in the development of physical dependence as exemplified by a hypothermic response which peaked 2-8 hours after initiation of withdrawal. Twenty-four hours post-withdrawal, opioid receptor binding was determined in the striatum using a selective...

journal_title：Brain research bulletin

authors： Steece KA,DeLeon-Jones FA,Meyerson LR,Lee JM,Fields JZ,Ritzmann RF

更新日期：1986-08-01 00:00:00

abstract：:The assumption was made that investigatory behaviors (i.e., ano-genital and general body sniffing) of a female conspecific by a mature male rat, has positive hedonic characteristics. Because reduced interest in pleasurable events (i.e., anhedonia) is diagnostically related to depressive behavior, the hypothesis was ad...

journal_title：Brain research bulletin

authors： Paré WP

更新日期：2000-12-01 00:00:00

abstract：:In this study, we compared the depression-like symptoms induced by olfactory bulbectomy (OBX) in the two inbred Wistar and Long Evans rat strains. We also analyzed the self-regulated oral intake of nicotine in these strains and the effect of nicotine on the depression-like symptoms of olfactory bulbectomy. Furthermore...

journal_title：Brain research bulletin

authors： Vieyra-Reyes P,Mineur YS,Picciotto MR,Túnez I,Vidaltamayo R,Drucker-Colín R

更新日期：2008-09-05 00:00:00

abstract：:The effect of lithium chloride on the activity of the afferent nerve fibers from the abdominal organs was studied in anesthetized rats. The administration of the lithium chloride solution (0.15 M) over the mesentery increased afferent discharge rate of the splanchnic and vagal gastric nerve. Injection of the same solu...

journal_title：Brain research bulletin

authors： Niijima A,Yamamoto T

更新日期：1994-01-01 00:00:00

abstract：:The changes of characteristics of dopamine (D1 and D2) and muscarinic receptors after acute and subacute administration of bicuculline were examined in rat brain. The results demonstrated that in striatal region, the Bmax of D2 receptor was significantly increased with no change of affinity after subacute administrati...

journal_title：Brain research bulletin

authors： Lim DK,Ito Y,Hoskins B,Ho IK

更新日期：1988-07-01 00:00:00

abstract：:The C57BL/6J (B6) inbred mouse strain was compared to the A/J inbred strain for motor activity in an open-field, exploration of a hole-board, motor coordination in the coat-hanger test, and spatial learning in the Morris water maze. B6 mice displayed a higher number of segment crossings in the open-field and of hole-p...

journal_title：Brain research bulletin

authors： Thifault S,Lalonde R,Sanon N,Hamet P

更新日期：2002-06-01 00:00:00

abstract：:Regions of the midbrain in the rat were stimulated electrically with bipolar electrodes to identify responsive, single neurons in the parafloccular lobule of the cerebellum. Eighty four percent (44/52) of the cells recorded in the paraflocculus showed evidence of a modulation in simple spike discharge activity (mossy ...

journal_title：Brain research bulletin

authors： Burne RA,Woodward DJ

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Deep brain stimulation (DBS) refers to the delivery of electric current to specific deep brain structures through implanted electrodes. Recently approved for use in United States, DBS to the anterior nucleus of thalamus (ANT) is a safe and effective alternative treatment for medically refractory seizures. De...

journal_title：Brain research bulletin

authors： Gimenes C,Malheiros JM,Battapady H,Tannus A,Hamani C,Covolan L

更新日期：2019-04-01 00:00:00

abstract：:The effects of changes in ambient and central temperature, amines, PGEu and pyrogen were investigated with respect to the mechanism of Na+-Ca++ ratio in the posterior hypothalamus of the unrestrained cat. Guide tubes were implanted bilaterally above the posterior hypothalamic area of 23 cats so as to accommodate push-...

journal_title：Brain research bulletin

authors： Myers RD,Simpson CW,Higgins D,Nattermann RA,Rice JC,Redgrave P,Metcalf G

更新日期：1976-05-01 00:00:00

abstract：:We have examined the effects of the presence of the mutated human presenilin 1 gene (M146L; hps1*) on lesion-induced sprouting in the hippocampus of the mouse (C57/CBA). The entorhinal cortex was unilaterally lesioned with ibotenic acid in adult, male mice. Four weeks later the subsequent axonal sprouting in the denta...

journal_title：Brain research bulletin

authors： Kadish I,Pradier L,van Groen T

更新日期：2002-03-15 00:00:00

abstract：:The effects of two indirect (dexfenfluramine and fluoxetine) and one direct (RU 24969) serotonergic agonists on diet selection over a 12-hr period were examined. Rats were habituated to eat, during the dark period, from two isoenergetic diets that differed in carbohydrate and protein content. Drugs were injected intra...

journal_title：Brain research bulletin

authors： Luo SQ,Li ET

更新日期：1990-06-01 00:00:00

abstract：:The subparafascicular thalamic nucleus (Spf) contains a substantial number of dopaminergic neurons. The present study was designed to investigate in the rat whether or not Spf neurons projecting to a variety of central nervous system structures are dopaminergic. The following eight structures were tested for projectio...

journal_title：Brain research bulletin

authors： Takada M

更新日期：1993-01-01 00:00:00

abstract：:Cell replacement therapy is of great interest as a long-term treatment of neurodegenerative diseases such as Parkinson's disease (PD). We have previously shown that Sertoli cells (SC) provide neurotrophic support to transplants of dopaminergic fetal neurons and NT2N neurons, derived from the human clonal precursors ce...

journal_title：Brain research bulletin

authors： Saporta S,Willing AE,Shamekh R,Bickford P,Paredes D,Cameron DF

更新日期：2004-12-15 00:00:00

abstract：:Aβ plaques of Alzheimer's disease (AD) are believed to precede cognitive deficits or clinical manifestation by decades. However, validated biomarkers for early diagnosis of the AD disease are still not available. In this present study, we combined MRI-based neuroimages and histological assessment of the glial response...

journal_title：Brain research bulletin

authors： Liu L,Liu Y,Li N,Huang R,Zheng X,Huang L,Hou S,Yuan Q

更新日期：2020-03-01 00:00:00

abstract：:We studied mitochondria in the satellite cell sheaths which envelope the spinal ganglion neurons of rabbits aged 12, 42, and 79 months. While the mean cytoplasmic volume of satellite cell sheaths did not change significantly with age, the mean percentage of cytoplasmic volume occupied by mitochondria decreased with ag...

journal_title：Brain research bulletin

authors： Martinelli C,Sartori P,Ledda M,Pannese E

更新日期：2003-07-15 00:00:00

abstract：:Serotonergic modulation of acetylcholine (ACh) release after neuron-specific increase of the expression of 5-HT(1B) receptors by gene transfer was studied in vitro and in vivo. The increased expression of the 5-HT(1B) receptor in vitro was induced by treating rat primary fetal septal cell cultures for 3 days with a vi...

journal_title：Brain research bulletin

authors： Riegert C,Rothmaier AK,Leemhuis J,Sexton TJ,Neumaier JF,Cassel JC,Jackisch R

更新日期：2008-07-01 00:00:00