Increased Th17 and Th22 Cell Percentages Predict Acute Lung Injury in Patients with Sepsis.

abstract：:In patients with congestive heart failure (CHF), a high prevalence of sleep-disordered breathing has been described. Cheyne-Stokes respiration (CSR) is present in up to 40% of patients with CHF. During the last decade, the medical treatment has been substantially improved. This study was designed to analyze the progno...

journal_title：Lung

authors： Hagenah G,Zapf A,Schüttert JB

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...

journal_title：Lung

authors： Ramos-Casals M,Kostov B,Brito-Zerón P,Sisó-Almirall A,Baughman RP,Autoimmune Big Data Study Group.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Patients with various chronic respiratory diseases have a higher incidence of gastroesophageal reflux disease (GERD)-related symptoms, but the mechanisms of the relationship between GERD symptoms and chronic obstructive pulmonary disease (COPD) remain unclear. The aim of the present study was to explore the ...

journal_title：Lung

authors： Liang BM,Feng YL

更新日期：2012-06-01 00:00:00

abstract：:Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...

journal_title：Lung

authors： Fujimoto K,Tsunoda T,Koizumi T,Kubo K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (NO) levels have been reported to be lower in patients with cystic fibrosis (CF) than in controls; however the mechanism(s) responsible and the effect on pathogenesis are unclear. The objective of these studies was to determine if the low levels of gas phase NO (gNO) could be reproduced ...

journal_title：Lung

authors： Ostrowski LE,Stewart D,Hazucha M

更新日期：2012-10-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...

journal_title：Lung

authors： Myint ZW,McCormick J,Chauhan A,Behrens E,Anthony LB

更新日期：2018-10-01 00:00:00

abstract：:Pulmonary histiocytosis X is characterized by an accumulation of CD-1-positive histiocytosis X cells in the lung, which also can be found in the bronchoalveolar lavage fluid (BALF). However, it has recently been demonstrated that CD-1-positive cells can also be detected in BALF of patients with other interstitial lung...

journal_title：Lung

authors： Auerswald U,Barth J,Magnussen H

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Although lung transplantation is the only means of survival for patients with end-stage pulmonary disease, outcomes from this intervention are inferior to other solid organ transplants. The reason for the poor outcomes may be linked to an early reaction, such as primary graft dysfunction, and associated with...

journal_title：Lung

authors： Nataatmadja M,Passmore M,Russell FD,Prabowo S,Corley A,Fraser JF

更新日期：2014-08-01 00:00:00

abstract：:Gastro-oesophageal reflux disease (GORD) is generally considered one of the three main causes of chronic cough, along with asthma and nasal disease. The diagnosis of GORD is often based upon a successful trial of anti-acid treatment however GORD is a complex condition taking many forms. Only recently have studies star...

journal_title：Lung

authors： Smith J,Woodcock A,Houghton L

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Up to 50% of patients suffer short-term postoperative adverse events (AEs) and metastatic recurrence in the long-term following curative-intent lung cancer resection. The association between AEs, particularly infectious in nature, and disease recurrence is controversial. We sought to evaluate the association...

journal_title：Lung

authors： Gowing S,Baker L,Tran A,Zhang Z,Ahn H,Ivanovic J,Anstee C,Grigor E,Gilbert S,Maziak DE,Shamji F,Sundaresan S,Villeneuve PJ,Seely AJE

更新日期：2020-12-01 00:00:00

abstract：:During acute asthma reversible increase in lung compliance and total lung capacity (TLC) have been observed. The magnitude of the increase in TLC, however, was found to be relatively small when TLC was measured radiographically. We wondered if structural distortion of the respiratory bellows develops during acute asth...

journal_title：Lung

authors： Park SS,Stein L,Zelefsky MN

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:This is a meta-analysis of the safety and efficacy of indacaterol in chronic obstructive pulmonary disease (COPD) with treatment duration of ≥12 weeks. METHODS:Randomized controlled trials (RCTs) reported in English (to September 30, 2012) were identified from PubMed, the Cochrane Library, Embase, websites,...

journal_title：Lung

authors： Jiang FM,Liang ZA,Zheng QL,Wang RC,Luo J,Li CT

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Nicorandil is a hybrid between nitrates and KATP channel opener activators. The aim of this study was to evaluate the nicorandil's effects on ischemia-reperfusion (IR) lung injury and examine the mechanism of its effects. METHODS:Isolated rat lungs were divided into 6 groups. In the sham group, the lungs were ...

journal_title：Lung

authors： Abe K,Horiguchi T,Enzan K,Masaki Y,Nishikawa T,Kimura T

更新日期：2020-04-01 00:00:00

abstract：:The role of leukotrienes in hypoxic vasoconstriction remains controversial. Our previous study using the lipoxygenase inhibitor BW 755C in dogs failed to show a substantive role for leukotrienes in hypoxic vasoconstriction. To clarify further the role of leukotrienes, we designed 3 protocols. In the first protocol, we...

journal_title：Lung

authors： Thomas HM 3rd,Sourour MS,Lopez D,Foster SH

更新日期：1989-01-01 00:00:00

abstract：:The efficacy of the docetaxel-carboplatin combination chemotherapy was studied in various phase II studies. Based on these data we aimed to test the regimen in previously untreated patients with advanced advanced non-smoking lung cancer (NSCLC) with docetaxel 80 mg/m2 a standard dose of carboplatin at AUC = 5, in an a...

journal_title：Lung

authors： Tsavaris N,Kosmas C,Skopelitis E,Gennatas K,Zorbala A,Papas P,Gouveris P,Antypas G,Rokana S,Tzelepis G

更新日期：2005-11-01 00:00:00

abstract：:Patients with pleural effusions frequently present a diagnostic and therapeutic challenge. The diagnosis is based on the interpretation of the results of thoracentesis or pleural biopsy. When a malignant tumor metastasizes to the pleura, tumor cells can be seeded over the mesothelial surface or in the subserous layer....

journal_title：Lung

authors： Mohamed KH,Mobasher AA,Yousef AI,Salah A,Ramadan MA,Emam AK,Alhayawan HM,Light RW

更新日期：2000-11-01 00:00:00

abstract：:The presence and distribution of acetylcholinesterase (AChE) and cholineacetyl transferase activities (Chat) were examined in the bronchus-associated lymphoid tissue (BALT) of juvenile, adult and old rats. Histoenzymatic and immunochemical methods were used in association with quantitative analysis of images and stati...

journal_title：Lung

authors： Cavallotti C,Tonnarini GF,Tranquilli Leali FM

更新日期：2004-01-01 00:00:00

abstract：:Reaginic antibodies in hay fever patients belong to IgE. The immunoglobulin sensitizes basophilic granulocytes and mast cells from homologous species and mediates the release of chemical mediators which cause allergic symptoms. The sensitization is due to the binding of IgE to receptors on the target cells through the...

journal_title：Lung

authors： Ishizaka K,Ishizaka T

更新日期：1978-01-01 00:00:00

abstract：:Immune cell airway infiltration and the bronchovascular remodeling process have shown to be promising in the understanding of bronchiolitis obliterans (BO) pathogenesis. In this study we sought to validate the importance of immune cells, whether diffusely distributed or forming lymphoid follicles, collagen density, an...

journal_title：Lung

authors： Garippo AL,Parra ER,Teodoro WR,Veloza AP,Yoshinari NH,Capelozzi VL

更新日期：2006-07-01 00:00:00

abstract：:This study demonstrates for the first time that endothelial cells freshly isolated from small pulmonary arteries of the rat, based on their electrophysiological profile, possess two distinct populations of cells. Immunohistochemical staining revealed the presence of both anti-Kv1.5 and anti-Kir2.1 immunoreactivity in ...

journal_title：Lung

authors： Hogg DS,McMurray G,Kozlowski RZ

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:To evaluate the cardio-pulmonary hemodynamics changes before and after valve treatment, and their correlation with lobe volume reduction. METHODS:This retrospective multicentre study included consecutive patients undergoing bronchoscopic valve treatment for heterogeneous emphysema. In addition to standard...

journal_title：Lung

authors： Fiorelli A,Cascone R,Natale G,Peritore V,Vanni C,Poggi C,Venuta F,Rendina EA,Santini M,Andreetti C

更新日期：2020-06-01 00:00:00

abstract：:The pathophysiology of cough variant asthma is poorly understood. In particular, the mechanisms that cause different symptoms in typical asthma (in which wheeze predominates) compared with cough variant asthma (in which cough predominates) have not been determined. Traditional explanations include higher wheezing thre...

journal_title：Lung

authors： Lougheed MD,Turcotte SE,Fisher T

更新日期：2012-02-01 00:00:00

abstract：:Allergen exposure in atopic asthmatic patients is associated with recruitment and activation of eosinophils in the airways. Once activated, eosinophils release toxic products, including the eosinophil cationic protein (ECP), able to damage bronchial structures and to increase bronchial hyperresponsiveness. With this b...

journal_title：Lung

authors： Oddera S,Silvestri M,Penna R,Galeazzi G,Crimi E,Rossi GA

更新日期：1998-01-01 00:00:00

abstract：:Treatment of allergic asthma with inhaled corticosteroids results in local down-regulation of proinflammatory cytokine synthesis and in marked decrease in tissue eosinophilia. Blood concentrations of inhaled corticosteroids, although significantly lower than those measured in the lung, may still have antiinflammatory ...

journal_title：Lung

authors： Lantero S,Oddera S,Silvestri M,Gonzalez Rodriguez R,Morelli MC,Rossi GA

更新日期：1999-01-01 00:00:00

abstract：:In critically ill patients, endotracheal intubation is associated with a high risk of complications, including severe hypoxemia and hypotension. The purpose of this review is to discuss the definitions, complications, airway assessment, and patient optimization with respect to these patients. In addition, we present d...

journal_title：Lung

authors： Griesdale DE,Henderson WR,Green RS

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme 2 (ACE2), an ACE homolog, hydrolyzes angiotensin II and opposes its actions, and plays a protective role in the pathogenesis of pulmonary arterial hypertension (PAH). However, the underlying mechanisms involved in the effect of ACE2 on PAH are still uncertain. In this study, we ...

journal_title：Lung

authors： Li G,Liu Y,Zhu Y,Liu A,Xu Y,Li X,Li Z,Su J,Sun L

更新日期：2013-08-01 00:00:00

abstract：:Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution. It plays important roles in various pathophysiological processes, including tissue remodeling, reproduction, lipid transport, complement regulation, and apoptosis. Clusterin appears to have two main isoforms that result from alternati...

journal_title：Lung

authors： Li H,Liu S,Zhu X,Yang S,Xiang J,Chen H

更新日期：2010-10-01 00:00:00

abstract：:Air concentration of isocyanates are associated with the frequency of induced diseases. Asthma, bronchitis and rhinitis, chronic obstructive lung disease, and allergic alveolitis, respectively, were observed in exposed workers. Inhalation challenge tests with isocyanates found some 14% of symptomatic persons immunolog...

journal_title：Lung

authors： Baur X

更新日期：1990-01-01 00:00:00

abstract：:Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...

journal_title：Lung

authors： Vantaggiato L,Perruzza M,Refini RM,Bergantini L,d'Alessandro M,Cameli P,Perruzza D,Bini L,Bargagli E,Landi C

更新日期：2020-10-01 00:00:00