Abstract:
:Pulmonary histiocytosis X is characterized by an accumulation of CD-1-positive histiocytosis X cells in the lung, which also can be found in the bronchoalveolar lavage fluid (BALF). However, it has recently been demonstrated that CD-1-positive cells can also be detected in BALF of patients with other interstitial lung diseases and in healthy smokers. We therefore examined the frequency of CD-1-positive cells in a pool of patients with different pulmonary disorders, according to their smoking habits and diagnoses. We have studied the bronchoalveolar lavage in patients with pulmonary histiocytosis X (n = 6), sarcoidosis (n = 88), and in 97 patients with other miscellaneous lung disorders by using the immunoperoxidase method to detect CD-1-positive cells on glass slides. All patients with histologically proven histiocytosis X displayed more than 5% CD-1-positive cells, whereas patients with other pulmonary disorders showed no more than 3.6% CD-1-positive BAL cells. The dividing line of 5% CD-1-positive cells was not influenced by patients' smoking habits. The identification of CD-1-positive cells in BALF appears to be useful in diagnosing pulmonary histiocytosis X.
journal_name
Lungjournal_title
Lungauthors
Auerswald U,Barth J,Magnussen Hdoi
10.1007/BF02714167subject
Has Abstractpub_date
1991-01-01 00:00:00pages
305-9issue
6eissn
0341-2040issn
1432-1750journal_volume
169pub_type
杂志文章相关文献
LUNG文献大全abstract::Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-014-9617-2
更新日期:2014-10-01 00:00:00
abstract::The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718155
更新日期:1990-01-01 00:00:00
abstract::Electronic noses (e-noses) are based on arrays of different sensor types that respond to specific features of an odorant molecule, mostly volatile organic compounds (VOCs). Differently from gas chromatography and mass spectrometry, e-noses can distinguish VOCs spectrum by pattern recognition. E-nose technology has suc...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-017-9987-3
更新日期:2017-04-01 00:00:00
abstract::Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...
journal_title:Lung
pub_type: 临床试验,杂志文章,评审
doi:10.1007/BF02718109
更新日期:1990-01-01 00:00:00
abstract::The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02714442
更新日期:1987-01-01 00:00:00
abstract::The efficacy of the docetaxel-carboplatin combination chemotherapy was studied in various phase II studies. Based on these data we aimed to test the regimen in previously untreated patients with advanced advanced non-smoking lung cancer (NSCLC) with docetaxel 80 mg/m2 a standard dose of carboplatin at AUC = 5, in an a...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2552-5
更新日期:2005-11-01 00:00:00
abstract::It is well known that exposure to hyperoxia results in lung inflammation and damage, which leads to the development of chronic lung disease. Previous studies have shown increased activities of antioxidant enzymes (AOE) in lung tissue from animals exposed to hyperoxia. We propose the hypothesis that the fetal type II p...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000006
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to perform a systematic review and meta-analysis of all randomized controlled trials that compared the efficacy of doublet versus single third-generation cytotoxic agent as first-line treatment for elderly patients with advanced non-small-cell lung cancer (NSCLC). METHODS:Several d...
journal_title:Lung
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00408-012-9399-3
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:The right ventricular ejection fraction (RVEF) is a surrogate marker of right ventricular function in pulmonary hypertension (PH), but its measurement is complicated and time consuming. The tricuspid annular plane systolic excursion (TAPSE) measures only the longitudinal component of RV contraction while the...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0089-7
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:We previously demonstrated that the exposure to hyperbaric hyperoxia increased respiratory system elastance and both the "ohmic" and viscoelastic components of inspiratory resistances, probably because of increased oxygen tension toxic effects. We presently investigated the possible consequences of a single ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-014-9576-7
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the clinical and radiological features of patients with fungal infection mimicking thoracic malignancy and to establish a diagnostic approach for both clinicians and radiologists to avoid misdiagnosis. METHODS:In this retrospective study, we reviewed clinical and com...
journal_title:Lung
pub_type: 杂志文章,多中心研究
doi:10.1007/s00408-013-9506-0
更新日期:2013-12-01 00:00:00
abstract::Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensa...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-008-9086-6
更新日期:2008-07-01 00:00:00
abstract::Lung cancer is currently one of the most common malignant diseases and is responsible for substantial mortality worldwide. Compared with never smokers, former smokers remain at relatively high risk for lung cancer, accounting for approximately half of all newly diagnosed cases in the US. Screening offers former smoker...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-013-9517-x
更新日期:2014-02-01 00:00:00
abstract::It has been reported that a low concentration of exogenously applied vasoactive intestinal peptide (VIP) suppresses the release of acetylcholine (ACh) from vagus nerve terminals in the ferret and feline trachea. There has been, however, no documentation of the prejunctional action of VIP in the human airway. We observ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00175944
更新日期:1994-01-01 00:00:00
abstract::Immune cell airway infiltration and the bronchovascular remodeling process have shown to be promising in the understanding of bronchiolitis obliterans (BO) pathogenesis. In this study we sought to validate the importance of immune cells, whether diffusely distributed or forming lymphoid follicles, collagen density, an...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2588-6
更新日期:2006-07-01 00:00:00
abstract::The pathophysiology of cough variant asthma is poorly understood. In particular, the mechanisms that cause different symptoms in typical asthma (in which wheeze predominates) compared with cough variant asthma (in which cough predominates) have not been determined. Traditional explanations include higher wheezing thre...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-011-9348-6
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:Bronchopleural fistula is a rare but potentially fatal complication of pulmonary resections and proper management is essential for its resolution. In this study, we analyzed the incidence of fistula after pulmonary resection and reported data about endoscopic and conservative treatments of this complicatio...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-016-9841-z
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:Sarcoidosis is a systemic granulomatous disease which predominantly affects the lungs, although granulomas can also involve all other organs, including the heart. Cardiac sarcoidosis (CS) may occur at any stage of the disease and may be the cause of sudden cardiac death, even in a previously asymptomatic p...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-015-9805-8
更新日期:2016-02-01 00:00:00
abstract::A multiuser system for whole body plethysmographic measurements and interpretation which has been developed under clinical conditions is described. The following measurements can be carried out in a rapid way and in one session with the patient: specific airway resistance during spontaneous breathing, determination of...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF02718260
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Recent studies have demonstrated non-inferiority of rivaroxaban when compared to warfarin for the treatment of pulmonary embolism and deep venous thrombosis. Analysis of data from the EINSTEIN trials has demonstrated that patients who received rivaroxaban had a shorter length of stay (LOS) compared to those ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-016-9898-8
更新日期:2016-08-01 00:00:00
abstract:: ...
journal_title:Lung
pub_type: 信件
doi:10.1007/s00408-018-0187-6
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:Nicorandil is a hybrid between nitrates and KATP channel opener activators. The aim of this study was to evaluate the nicorandil's effects on ischemia-reperfusion (IR) lung injury and examine the mechanism of its effects. METHODS:Isolated rat lungs were divided into 6 groups. In the sham group, the lungs were ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00339-0
更新日期:2020-04-01 00:00:00
abstract::Treatment of allergic asthma with inhaled corticosteroids results in local down-regulation of proinflammatory cytokine synthesis and in marked decrease in tissue eosinophilia. Blood concentrations of inhaled corticosteroids, although significantly lower than those measured in the lung, may still have antiinflammatory ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/pl00007642
更新日期:1999-01-01 00:00:00
abstract::In previous studies, we showed that Fischer rats fed 175 mg/kg of amiodarone accumulated large amounts of drug and metabolite in the lung and developed pulmonary toxicity, whereas Wistar rats fed the same drug dose had significantly less amiodarone in the lung and did not develop pulmonary inflammation. The present st...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00167949
更新日期:1996-01-01 00:00:00
abstract::To determine the role of the alveolar pores in cigarette smoke-induced lung disease, we examined the alveolar pores of guinea pigs exposed to cigarette smoke for 12 months, and compared these data to those obtained from sham-smoked animals, correlating the data with airspace size and lung function. We found that the s...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000048
更新日期:2001-01-01 00:00:00
abstract::The effect of beta 2-adrenoceptor agonists on airway smooth muscle relaxation may be subject to desensitization. It could be modified by glucocorticosteroid treatment. An increase in the beta 2 agonist response by glucocorticosteroids in vitro has been described. We studied the effects of acute and chronic treatment w...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00176895
更新日期:1995-01-01 00:00:00
abstract::The original version of this article contained an error in the usage of the term "false positive rate". The intention of the authors in those instances was simply to compare the absolute percentage of false positive results in the study vs the NLST, not to make any observations about false positive rate in the strict ...
journal_title:Lung
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00408-019-00269-6
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Prolonged exposure to crystalline silica leads to persistent pulmonary inflammation and progressive fibrosis. Connective tissue growth factor (CTGF) has emerged as a potent proinflammatory and profibrotic regulator to participate in a variety of chronic inflammatory diseases. However, the role of CTGF in sil...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00272-x
更新日期:2019-12-01 00:00:00
abstract::The major goal of all diagnostic and therapeutic efforts in childhood asthma is to prevent progression of lung disease into adulthood. To improve the uncomfortable situation of underdiagnosis and undertreatment and to lower the risk of acquiring irreversible lung damage, an optimal co-working relationship between fami...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718166
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcomes. This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five-year period. Further, we compared our results to the 'World Association of Sarcoi...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-017-0015-4
更新日期:2017-08-01 00:00:00