VIP antagonists enhance excitatory cholinergic neurotransmission in the human airway.

abstract：BACKGROUND:Microbiological cultures are the mainstay of the diagnosis of tuberculosis (TB). False-positive TB results lead to significant unnecessary therapeutic and economic burden and are frequently caused by laboratory cross-contamination. The aim of this meta-analysis was to quantify the prevalence of laboratory cr...

journal_title：Lung

authors： Barac A,Karimzadeh-Esfahani H,Pourostadi M,Rahimi MT,Ahmadpour E,Rashedi J,Mahdavipoor B,Kafil HS,Spotin A,Abate KH,Mathioudakis AG,Asgharzadeh M

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:Pulmonary hypertension (PH) due to COPD has dismal prognosis. We reviewed the long-term effect of PH-target therapy in severe PH-COPD. METHOD:Patients attending our PH-clinic were reviewed for PH-COPD receiving PH-target therapy. Baseline characteristics, death/transplantation until 2014, therapy, NYHA functio...

journal_title：Lung

authors： Fossati L,Müller-Mottet S,Hasler E,Speich R,Bloch KE,Huber LC,Ulrich Somaini S

更新日期：2014-12-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Malignant mesothelioma is an aggressive tumor of serosal surfaces that is closely associated with asbestos exposure which induces oxidative stress. Heme oxygenase (HO)-1, a rate-limiting enzyme of heme degradation, plays a protective role against oxidative stress. The HO-1 gene promoter carries (GT)n repeats...

journal_title：Lung

authors： Murakami A,Fujimori Y,Yoshikawa Y,Yamada S,Tamura K,Hirayama N,Terada T,Kuribayashi K,Tabata C,Fukuoka K,Tamaoki T,Nakano T

更新日期：2012-06-01 00:00:00

abstract：:It is well known that exposure to hyperoxia results in lung inflammation and damage, which leads to the development of chronic lung disease. Previous studies have shown increased activities of antioxidant enzymes (AOE) in lung tissue from animals exposed to hyperoxia. We propose the hypothesis that the fetal type II p...

journal_title：Lung

authors： Bhandari V,Maulik N,Kresch M

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00

abstract：:The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of t...

journal_title：Lung

authors： Lee YK,Oh YM,Lee JH,Kim EK,Lee JH,Kim N,Seo JB,Lee SD,KOLD Study Group.

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:Melanocortin 3 Receptor (MC3R) is one of the families of seven-transmembrane G-protein-coupled receptors, and a recent study showed that MCR3 promoter polymorphism was significantly associated with the susceptibility of tuberculosis (TB) in South African population. METHODS:We analyzed six MC3R polymorphisms t...

journal_title：Lung

authors： Park BL,Kim LH,Namgoong S,Kim JO,Kim JY,Chang HS,Park JS,Jang AS,Park SW,Kim DJ,Kim KU,Kim YG,Uh ST,Seo KH,Kim YH,Park CS,Shin HD

更新日期：2014-12-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：:Patients with pleural effusions frequently present a diagnostic and therapeutic challenge. The diagnosis is based on the interpretation of the results of thoracentesis or pleural biopsy. When a malignant tumor metastasizes to the pleura, tumor cells can be seeded over the mesothelial surface or in the subserous layer....

journal_title：Lung

authors： Mohamed KH,Mobasher AA,Yousef AI,Salah A,Ramadan MA,Emam AK,Alhayawan HM,Light RW

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) has been shown to be associated with adverse outcomes in left-sided heart failure, pulmonary hypertension, and in patients in the ICU. However, the role of RDW is unknown in patients with obstructive sleep apnea syndrome (OSAS), especially in OSAS patients with cardiovascula...

journal_title：Lung

authors： Ozsu S,Abul Y,Gulsoy A,Bulbul Y,Yaman S,Ozlu T

更新日期：2012-06-01 00:00:00

abstract：:A multiuser system for whole body plethysmographic measurements and interpretation which has been developed under clinical conditions is described. The following measurements can be carried out in a rapid way and in one session with the patient: specific airway resistance during spontaneous breathing, determination of...

journal_title：Lung

authors： Zaiss AW,Matthys H

更新日期：1990-01-01 00:00:00

abstract：:There is a lack of evidence about whether menopausal status influences the effect of smoking on lung function. This study examined the association between smoking and menopausal status and lung function independent of each other. Data were from a cohort of women attending the 21-year follow-up of the Mater University ...

journal_title：Lung

authors： Hayatbakhsh MR,Najman JM,O'Callaghan MJ,Williams GM,Paydar A,Clavarino A

更新日期：2011-02-01 00:00:00

abstract：INTRODUCTION:To evaluate the cardio-pulmonary hemodynamics changes before and after valve treatment, and their correlation with lobe volume reduction. METHODS:This retrospective multicentre study included consecutive patients undergoing bronchoscopic valve treatment for heterogeneous emphysema. In addition to standard...

journal_title：Lung

authors： Fiorelli A,Cascone R,Natale G,Peritore V,Vanni C,Poggi C,Venuta F,Rendina EA,Santini M,Andreetti C

更新日期：2020-06-01 00:00:00

abstract：:The role of leukotrienes in hypoxic vasoconstriction remains controversial. Our previous study using the lipoxygenase inhibitor BW 755C in dogs failed to show a substantive role for leukotrienes in hypoxic vasoconstriction. To clarify further the role of leukotrienes, we designed 3 protocols. In the first protocol, we...

journal_title：Lung

authors： Thomas HM 3rd,Sourour MS,Lopez D,Foster SH

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Although lung transplantation is the only means of survival for patients with end-stage pulmonary disease, outcomes from this intervention are inferior to other solid organ transplants. The reason for the poor outcomes may be linked to an early reaction, such as primary graft dysfunction, and associated with...

journal_title：Lung

authors： Nataatmadja M,Passmore M,Russell FD,Prabowo S,Corley A,Fraser JF

更新日期：2014-08-01 00:00:00

abstract：:In critically ill patients, endotracheal intubation is associated with a high risk of complications, including severe hypoxemia and hypotension. The purpose of this review is to discuss the definitions, complications, airway assessment, and patient optimization with respect to these patients. In addition, we present d...

journal_title：Lung

authors： Griesdale DE,Henderson WR,Green RS

更新日期：2011-06-01 00:00:00

abstract：:The angiogenesis system has been implicated in inflammatory and neoplastic processes; nevertheless, it has been little studied in relation to the pleural space. Our aim is to analyze pleural and plasma levels of the activators--vascular endothelial growth factor, basic fibroblastic growth factor, and inhibitors--endos...

journal_title：Lung

authors： Ruiz E,Alemán C,Alegre J,Monasterio J,Segura RM,Armadans L,Vázquez A,Soriano T,Fernández de Sevilla T

更新日期：2005-05-01 00:00:00

abstract：:We report two patients with atopic cough due to Basidiomycetes antigen. One patient was a 27 year-old woman and the other was a 17 year-old boy. Both patients visited our hospital because of severe nonproductive cough. They did not have bronchial hyperresponsiveness to methacholine or heightened bronchomotor tone. Bro...

journal_title：Lung

authors： Ogawa H,Fujimura M,Tofuku Y

更新日期：2004-01-01 00:00:00

abstract：:A 41-year-old woman presented with chest pain and a cough. There was a solitary pulmonary nodule in the upper-left lobe. The patient had no history of neoplasm except a hysterectomy for uterine leiomyoma five years before. Six months after the first presentation, the tumor showed a gradual increase in size; an explora...

journal_title：Lung

authors： Sapmaz F,Ergin M,Katrancioglu O,Gonlugur T,Gonlugur U,Elagoz S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:In immunocompromised patients with pulmonary infiltrates, transbronchial lung biopsies (TBB) obtained by forceps has been shown to increase the diagnostic yield over simple bronchoalveolar lavage. Cryo-TBB is a novel modality for obtaining lung biopsies. We aimed to evaluate for the first time the efficacy a...

journal_title：Lung

authors： Fruchter O,Fridel L,Rosengarten D,Rahman NA,Kramer MR

更新日期：2013-12-01 00:00:00

abstract：:The effect of beta 2-adrenoceptor agonists on airway smooth muscle relaxation may be subject to desensitization. It could be modified by glucocorticosteroid treatment. An increase in the beta 2 agonist response by glucocorticosteroids in vitro has been described. We studied the effects of acute and chronic treatment w...

journal_title：Lung

authors： Seco AJ,Salgueiro ME,Manso G

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Depression is an important comorbidity for patients with chronic obstructive pulmonary disease (COPD). The association between depression and acute exacerbations of COPD is unknown. This study was designed to determine the frequency of COPD exacerbations in outpatients with and without depressive symptoms. ...

journal_title：Lung

authors： Jennings JH,Digiovine B,Obeid D,Frank C

更新日期：2009-03-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PCP) is the most common presenting symptom in patients with the acquired immunodeficiency syndrome (AIDS). Clinical trials have shown that inhaled pentamidine, delivered by nebulizer, is an effective prophylaxis for PCP in high-risk patients, and can be used to treat mild to moderate ep...

journal_title：Lung

authors： Newman SP,Simonds AK

更新日期：1990-01-01 00:00:00

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：:In previous studies, we showed that Fischer rats fed 175 mg/kg of amiodarone accumulated large amounts of drug and metabolite in the lung and developed pulmonary toxicity, whereas Wistar rats fed the same drug dose had significantly less amiodarone in the lung and did not develop pulmonary inflammation. The present st...

journal_title：Lung

authors： Wilson BD,Lippmann ML

更新日期：1996-01-01 00:00:00

abstract：:The presence and distribution of acetylcholinesterase (AChE) and cholineacetyl transferase activities (Chat) were examined in the bronchus-associated lymphoid tissue (BALT) of juvenile, adult and old rats. Histoenzymatic and immunochemical methods were used in association with quantitative analysis of images and stati...

journal_title：Lung

authors： Cavallotti C,Tonnarini GF,Tranquilli Leali FM

更新日期：2004-01-01 00:00:00

abstract：:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is recognized as a preneoplastic condition by the World Health Organization. We reviewed our experience with 30 patients and performed a systematic review of the English literature to collect best evidence on the clinical features and disease cours...

journal_title：Lung

authors： Wirtschafter E,Walts AE,Liu ST,Marchevsky AM

更新日期：2015-10-01 00:00:00

abstract：:Occupational exposure to oyster mushroom (Pleurotus ostreatus) has been associated with obstructive lung disease. Previously, we studied an extract of oyster mushroom (OME) and determined that it causes dose-dependent contractions of nonsensitized guinea pig trachea (GPT). We extend these studies to the investigation ...

journal_title：Lung

authors： Schachter EN,Zuskin E,Pucarin-Cvetkovic J,Chiarelli A,Goswami S

更新日期：2011-08-01 00:00:00

abstract：:The effect of tetraethylammonium (TEA) and K+ on contractions to histamine and acetylcholine have been compared in the pig isolated trachea using organ bath and sucrose-gap techniques. Histamine elicited weak contractions, compared with acetylcholine; however, these contractions were markedly potentiated by pretreatme...

journal_title：Lung

authors： Mitchell HW

更新日期：1987-01-01 00:00:00