Response to oyster mushroom (Pleurotus ostreatus) extract by sensitized and nonsensitized guinea pig trachea.

abstract：:Gastro-oesophageal reflux disease (GORD) is generally considered one of the three main causes of chronic cough, along with asthma and nasal disease. The diagnosis of GORD is often based upon a successful trial of anti-acid treatment however GORD is a complex condition taking many forms. Only recently have studies star...

journal_title：Lung

authors： Smith J,Woodcock A,Houghton L

更新日期：2010-01-01 00:00:00

abstract：:Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...

journal_title：Lung

authors： Keeney SE,Oelberg DG

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Sildenafil was the only phosphodiesterase-5 inhibitor available for the treatment of pulmonary arterial hypertension (PAH) until the approval and availability of once-daily tadalafil. Since no direct comparative study is likely to be performed between these agents, we sought to evaluate the feasibility of tr...

journal_title：Lung

authors： Shlobin OA,Brown AW,Weir N,Ahmad S,Lemma M,Nathan SD

更新日期：2012-10-01 00:00:00

abstract：:We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...

journal_title：Lung

authors： Sagawa T,Kida T,Inaba T,Yokota I,Sagawa R,Kasahara A,Kaneshita S,Inoue T,Nagahara H,Fujioka K,Wada M,Kohno M,Kawahito Y

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a systemic granulomatous disease which predominantly affects the lungs, although granulomas can also involve all other organs, including the heart. Cardiac sarcoidosis (CS) may occur at any stage of the disease and may be the cause of sudden cardiac death, even in a previously asymptomatic p...

journal_title：Lung

authors： Martusewicz-Boros MM,Boros PW,Wiatr E,Kempisty A,Piotrowska-Kownacka D,Roszkowski-Śliż K

更新日期：2016-02-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：:The effects of a pulmonary rehabilitation program on 44 patients with chronic obstructive pulmonary disease (COPD) were compared to a control group. The treated group was admitted to the program for a period of three months. The program consisted of several parts, such as physical training, health education, and psych...

journal_title：Lung

authors： Cox NJ,Hendricks JC,Binkhorst RA,van Herwaarden CL

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:Flexible fiberoptic bronchoscopy (FFB) plays an important role in the surveillance of cystic fibrosis (CF) patients after lung transplantation (LTx). With rapid onset and clearance, propofol provides a safe and efficient method for sedation during FFB, yet sedation requirements for CF patients are not well...

journal_title：Lung

authors： Ho C,Hayes D Jr,Khosravi M,Splaingard ML,Tumin D,Lloyd EA

更新日期：2018-08-01 00:00:00

abstract：:The effect of beta 2-adrenoceptor agonists on airway smooth muscle relaxation may be subject to desensitization. It could be modified by glucocorticosteroid treatment. An increase in the beta 2 agonist response by glucocorticosteroids in vitro has been described. We studied the effects of acute and chronic treatment w...

journal_title：Lung

authors： Seco AJ,Salgueiro ME,Manso G

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...

journal_title：Lung

authors： Hong ZY,Lee CG,Shim HS,Lee EJ,Song KH,Choi BW,Cho J,Story MD

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme 2 (ACE2), an ACE homolog, hydrolyzes angiotensin II and opposes its actions, and plays a protective role in the pathogenesis of pulmonary arterial hypertension (PAH). However, the underlying mechanisms involved in the effect of ACE2 on PAH are still uncertain. In this study, we ...

journal_title：Lung

authors： Li G,Liu Y,Zhu Y,Liu A,Xu Y,Li X,Li Z,Su J,Sun L

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Pulmonary hypertension (PH) due to COPD has dismal prognosis. We reviewed the long-term effect of PH-target therapy in severe PH-COPD. METHOD:Patients attending our PH-clinic were reviewed for PH-COPD receiving PH-target therapy. Baseline characteristics, death/transplantation until 2014, therapy, NYHA functio...

journal_title：Lung

authors： Fossati L,Müller-Mottet S,Hasler E,Speich R,Bloch KE,Huber LC,Ulrich Somaini S

更新日期：2014-12-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：:An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may contribute to the pathogenesis of IPF. The neutrophil FcγRIIIb receptor occurs in two codominantly expressed allelic variants, NA1 and N...

journal_title：Lung

authors： Bournazos S,Bournazou I,Murchison JT,Wallace WA,McFarlane P,Hirani N,Simpson AJ,Dransfield I,Hart SP

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Melanocortin 3 Receptor (MC3R) is one of the families of seven-transmembrane G-protein-coupled receptors, and a recent study showed that MCR3 promoter polymorphism was significantly associated with the susceptibility of tuberculosis (TB) in South African population. METHODS:We analyzed six MC3R polymorphisms t...

journal_title：Lung

authors： Park BL,Kim LH,Namgoong S,Kim JO,Kim JY,Chang HS,Park JS,Jang AS,Park SW,Kim DJ,Kim KU,Kim YG,Uh ST,Seo KH,Kim YH,Park CS,Shin HD

更新日期：2014-12-01 00:00:00

abstract：:Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...

journal_title：Lung

authors： Hu Y,Peng J,Feng D,Chu L,Li X,Jin Z,Lin Z,Zeng Q

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The cardinal symptom of pulmonary hypertension (PH) is dyspnea on exertion, leading to decreased activity in daily living. The aim of this study was to analyze daily physical activity in incident patients with arterial or chronic thromboembolic PH (PAH/CTEPH) and to investigate its correlation with pulmona...

journal_title：Lung

authors： Saxer S,Lichtblau M,Berlier C,Hasler ED,Schwarz EI,Ulrich S

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...

journal_title：Lung

authors： Myint ZW,McCormick J,Chauhan A,Behrens E,Anthony LB

更新日期：2018-10-01 00:00:00

abstract：:Along with upper airway cough syndrome (formerly, postnasal drip syndrome) and eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), gastroesophageal reflux disease (GERD) is generally considered among the most common etiologies of chronic cough. Indeed, cough management guidelines published...

journal_title：Lung

authors： Kahrilas PJ,Smith JA,Dicpinigaitis PV

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Depression is an important comorbidity for patients with chronic obstructive pulmonary disease (COPD). The association between depression and acute exacerbations of COPD is unknown. This study was designed to determine the frequency of COPD exacerbations in outpatients with and without depressive symptoms. ...

journal_title：Lung

authors： Jennings JH,Digiovine B,Obeid D,Frank C

更新日期：2009-03-01 00:00:00

abstract：:Albumin diffusion measured in an isolated segment of rabbit lung interstitium with a radioactive tracer ((125)I-albumin) technique was independent of albumin concentration and similar to the free diffusion of albumin in water (Qiu et al, 1998. J Appl Physiol 85: 575-583). We studied the effect of hyaluronidase on the ...

journal_title：Lung

authors： Qiu XL,Brown LV,Parameswaran S,Marek VW,Ibbott GS,Lai-Fook SJ

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Acute exacerbations (AE) in patients with COPD are associated with a decline in lung function, increased risk of hospitalization, and mortality. In this cross-sectional study we tested whether the level of objectively measured daily physical activity and exercise capacity are associated with the number of COPD ...

journal_title：Lung

authors： Schönmann M,Sievi NA,Clarenbach CF,Brack T,Brutsche M,Frey M,Irani S,Leuppi JD,Ruediger J,Senn O,Thurnheer R,Kohler M

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:This study was conducted to investigate the percentages of Th22 and Th17 cells in the peripheral blood of septic patients with and without acute lung injury (ALI) and their clinical significance. METHODS:A total of 479 patients were divided into non-ALI and ALI groups. The percentages of Th22 and Th17 cells an...

journal_title：Lung

authors： Li G,Zhang L,Han N,Zhang K,Li H

更新日期：2020-08-01 00:00:00

abstract：:Pulmonary histiocytosis X is characterized by an accumulation of CD-1-positive histiocytosis X cells in the lung, which also can be found in the bronchoalveolar lavage fluid (BALF). However, it has recently been demonstrated that CD-1-positive cells can also be detected in BALF of patients with other interstitial lung...

journal_title：Lung

authors： Auerswald U,Barth J,Magnussen H

更新日期：1991-01-01 00:00:00

abstract：:Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...

journal_title：Lung

authors： Barreiro TJ,Gemmel D

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Recent studies have shown the importance of Th17 cells in the development of allergic airway diseases. We examined Dermatophagoides pteronyssinus-induced changes in peripheral blood Th17 cells to establish the importance of these cells in late-phase allergic inflammation in patients with allergic rhinitis (A...

journal_title：Lung

authors： Bajoriuniene I,Malakauskas K,Lavinskiene S,Jeroch J,Gasiuniene E,Vitkauskiene A,Sakalauskas R

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Malignant mesothelioma is an aggressive tumor of serosal surfaces that is closely associated with asbestos exposure which induces oxidative stress. Heme oxygenase (HO)-1, a rate-limiting enzyme of heme degradation, plays a protective role against oxidative stress. The HO-1 gene promoter carries (GT)n repeats...

journal_title：Lung

authors： Murakami A,Fujimori Y,Yoshikawa Y,Yamada S,Tamura K,Hirayama N,Terada T,Kuribayashi K,Tabata C,Fukuoka K,Tamaoki T,Nakano T

更新日期：2012-06-01 00:00:00

abstract：:Cancer-testis antigens (CTAs) are expressed only in many cancers and limited immunoprivileged sites such as the testis and placenta. Dendritic cells (DCs) and CD8+ T lymphocytes (CTLs) play roles in the immune responses to tumor growth and may affect the prognosis of cancers. This study was designed to investigate the...

journal_title：Lung

authors： Kim SH,Lee S,Lee CH,Lee MK,Kim YD,Shin DH,Choi KU,Kim JY,Park DY,Sol MY

更新日期：2009-11-01 00:00:00

abstract：:During acute asthma reversible increase in lung compliance and total lung capacity (TLC) have been observed. The magnitude of the increase in TLC, however, was found to be relatively small when TLC was measured radiographically. We wondered if structural distortion of the respiratory bellows develops during acute asth...

journal_title：Lung

authors： Park SS,Stein L,Zelefsky MN

更新日期：1993-01-01 00:00:00