Physical activity in incident patients with pulmonary arterial and chronic thromboembolic hypertension.

abstract：:Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensa...

journal_title：Lung

authors： Kullmann T,Barta I,Antus B,Horváth I

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：ABSTARCT:New anti-fibrotic agents for idiopathic pulmonary fibrosis (IPF) were approved based on the results of forced vital capacity (FVC) trends, although concerns were raised about the reliability of FVC as the only endpoint parameter. We hypothesized that IPF-specific multi-dimensional scores (Composite Physiologic...

journal_title：Lung

authors： Hosein K,Le J,Mura M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a deadly disease, and the molecular mechanism of PAH has not been clarified clearly. The objective of this study was to identify possible biomarkers and explore the potential mechanisms of Schistosoma-induced PAH. METHODS:GSE49114 RNA-Seq data developed from mouse wh...

journal_title：Lung

authors： Sun Y,Lin X,Li L

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the exposure to hyperbaric hyperoxia increased respiratory system elastance and both the "ohmic" and viscoelastic components of inspiratory resistances, probably because of increased oxygen tension toxic effects. We presently investigated the possible consequences of a single ...

journal_title：Lung

authors： Rubini A,Porzionato A,Sarasin G,Zara S,Macchi V,Camporesi E,Bosco G

更新日期：2014-08-01 00:00:00

abstract：:The normal balance between coagulation and fibrinolysis in the pleural cavity is poorly understood despite the critical role of the pleura in the movement of the lungs. To determine the fibrinolytic activity and the interaction between plasminogen activators and their inhibitors in the normal pleural space, we tested ...

journal_title：Lung

authors： Li XY,Brown GM,Lamb D,Donaldson K

更新日期：1990-01-01 00:00:00

abstract：:The purpose of this study was to examine the lung pathogenesis of murine gammaherpesvirus (MHV-68) infection in mice that lack CC chemokine receptor CCR2, an important receptor for macrophage recruitment to sites of inflammation. BALB/c and CCR2(-/-) mice were inoculated intranasally (i.n.) with MHV-68 and samples wer...

journal_title：Lung

authors： Cadillac JM,Sigler RE,Weinberg JB,Lutzke ML,Rochford R

更新日期：2005-07-01 00:00:00

abstract：:Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...

journal_title：Lung

authors： Larsson S

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Driving pressure (DP) while on ECMO has been studied in acute respiratory distress syndrome (ARDS) but no studies exist in those on ECMO without ARDS. We aimed to study association of mortality with DP in all patients on ECMO and compare change in DP before and after initiation of ECMO. METHODS:Consecutiv...

journal_title：Lung

authors： Gupta E,Awsare B,Hirose H,Cavarocchi N,Baram M

更新日期：2020-10-01 00:00:00

abstract：:Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...

journal_title：Lung

authors： Muyal JP,Muyal V,Kotnala S,Kumar D,Bhardwaj H

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Transbronchial lung biopsy (TBBX) is a common respiratory diagnostic procedure performed to investigate several lung diseases. There are different types of forceps used to perform this procedure. The alligator and cupped (oval) forceps are most commonly used ones. To date, there are few studies that have com...

journal_title：Lung

authors： Almadani A,Ping MNY,Deenadayalu A,Saunders J,O'Brien A

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal fibrosing lung disease with a median survival of approximately 3 years after diagnosis. The only medical option to improve survival in IPF is lung transplantation (LTX). The purpose of this study was to evaluate trajectory data of IPF patients...

journal_title：Lung

authors： ten Klooster L,Nossent GD,Kwakkel-van Erp JM,van Kessel DA,Oudijk EJ,van de Graaf EA,Luijk B,Hoek RA,van den Blink B,van Hal PT,Verschuuren EA,van der Bij W,van Moorsel CH,Grutters JC

更新日期：2015-12-01 00:00:00

abstract：:Six European treatment centers contributed to a controlled trial to study nocturnal hypoxemia in COPD patients having daytime PaO2 of 60-70 mmHg. The trial is composed of two parts: first, patients inclusion, taking men aged under 70 years, excluding sleep apnea syndrome and all other concomitant pathologies leading t...

journal_title：Lung

authors： Levi-Valensi P,Aubry P,Rida Z

更新日期：1990-01-01 00:00:00

abstract：:In critically ill patients, endotracheal intubation is associated with a high risk of complications, including severe hypoxemia and hypotension. The purpose of this review is to discuss the definitions, complications, airway assessment, and patient optimization with respect to these patients. In addition, we present d...

journal_title：Lung

authors： Griesdale DE,Henderson WR,Green RS

更新日期：2011-06-01 00:00:00

abstract：:The early pathogenic events in cystic fibrosis (CF) include colonization of Pseudomonas in the lung, airway inflammation, and mucus hypersecretion with airway obstruction. The primary mechanisms leading to chronic infection and inflammation are not well understood. One possible explanation for this cascade of events i...

journal_title：Lung

authors： Voynow JA,Selby DM,Rose MC

更新日期：1998-01-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：:To determine the role of the alveolar pores in cigarette smoke-induced lung disease, we examined the alveolar pores of guinea pigs exposed to cigarette smoke for 12 months, and compared these data to those obtained from sham-smoked animals, correlating the data with airspace size and lung function. We found that the s...

journal_title：Lung

authors： Wright JL

更新日期：2001-01-01 00:00:00

abstract：:Allergen exposure in atopic asthmatic patients is associated with recruitment and activation of eosinophils in the airways. Once activated, eosinophils release toxic products, including the eosinophil cationic protein (ECP), able to damage bronchial structures and to increase bronchial hyperresponsiveness. With this b...

journal_title：Lung

authors： Oddera S,Silvestri M,Penna R,Galeazzi G,Crimi E,Rossi GA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...

journal_title：Lung

authors： Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

更新日期：2018-12-01 00:00:00

abstract：:High concentrations of tumor necrosis factor-a (TNF), as well as excess of polymorphonuclear leukocytes (PMNs), are present in pleural fluid of patients with complicated parapneumonic effusion (CPPE). Several studies have shown that PMNs are capable of secreting TNF. However, the correlation between levels of TNF and ...

journal_title：Lung

authors： Odeh M,Sabo E,Srugo I,Oliven A

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) has been shown to be associated with adverse outcomes in left-sided heart failure, pulmonary hypertension, and in patients in the ICU. However, the role of RDW is unknown in patients with obstructive sleep apnea syndrome (OSAS), especially in OSAS patients with cardiovascula...

journal_title：Lung

authors： Ozsu S,Abul Y,Gulsoy A,Bulbul Y,Yaman S,Ozlu T

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The relationship between asthma and obesity is well established, although the pathophysiological mechanisms linking both diseases remain unknown. Adiponectin is a hormone secreted by adipose cells, plays a role in the modulation of inflammation and may be the key linking these two types of inflammation. METHOD...

journal_title：Lung

authors： de Lima Azambuja R,da Costa Santos Azambuja LS,Costa C,Rufino R

更新日期：2015-10-01 00:00:00

abstract：:The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...

journal_title：Lung

authors： Nadal D,Ogra PL

更新日期：1990-01-01 00:00:00

abstract：:To explore further the possible etiologic role of mycobacteria in the development of sarcoidosis, we measured free, nonbound tuberculostearic acid (TSA, 10-methyloctadecanoic), a component of mycobacteria, in the sera of subjects with sarcoidosis or active untreated pulmonary tuberculosis and in healthy controls by us...

journal_title：Lung

authors： Almenoff PL,Brooks JB,Johnson A,Lesser M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. It is not known which clinical markers are predictive of PH in COPD. The goal of this study was to develop a clinical tool to identify patients who should be sent for ini...

journal_title：Lung

authors： Gartman EJ,Blundin M,Klinger JR,Yammine J,Roberts MB,Dennis McCool F

更新日期：2012-02-01 00:00:00

abstract：:Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...

journal_title：Lung

authors： Bohadana AB,Michaely JP

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:Pulmonary arteriovenous malformations (PAVMs) are most commonly associated with hereditary hemorrhagic telangiectasia (HHT). Patients with PAVMs can present with serious complications including stroke, transient ischemic attack (TIA), and brain abscess. PAVMs are rare in non-HHT patients and little is known abo...

journal_title：Lung

authors： Albitar HAH,Segraves JM,Almodallal Y,Pinto CA,De Moraes AG,Iyer VN

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to compare the risk factors, clinical characteristics, and complications of respiratory distress syndrome (RDS) in infants delivered very preterm, late preterm, and term in order to help optimize the management of RDS in neonates. METHODS:A retrospective study was conducted on ...

journal_title：Lung

authors： Sun H,Xu F,Xiong H,Kang W,Bai Q,Zhang Y,Zhou C,Zhuang F,Wang X,Zhu C

更新日期：2013-08-01 00:00:00

abstract：:Respiratory adaptation during sleep improves with growth. The most vulnerable period for respiratory adaptation to sleep is from birth to 3 months of age. Factors that favor vulnerability are immaturity in ventilatory control and high rib cage compliance which impairs its effectiveness for ventilation. Improvement in ...

journal_title：Lung

authors： Gaultier C

更新日期：1990-01-01 00:00:00