Effect of hyaluronidase on albumin diffusion in lung interstitium.

abstract：:Recently, active remodeling may indicate a good prognosis in idiopathic interstitial pneumonias. In this study we sought to validate the importance of the collagen/elastic system in the extracellular matrix remodeling and to study the relationships between the collagen/elastic system in nonspecific interstitial idiopa...

journal_title：Lung

authors： Felício CH,Parra ER,Capelozzi VL

更新日期：2007-01-01 00:00:00

abstract：:An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may contribute to the pathogenesis of IPF. The neutrophil FcγRIIIb receptor occurs in two codominantly expressed allelic variants, NA1 and N...

journal_title：Lung

authors： Bournazos S,Bournazou I,Murchison JT,Wallace WA,McFarlane P,Hirani N,Simpson AJ,Dransfield I,Hart SP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Microbiological cultures are the mainstay of the diagnosis of tuberculosis (TB). False-positive TB results lead to significant unnecessary therapeutic and economic burden and are frequently caused by laboratory cross-contamination. The aim of this meta-analysis was to quantify the prevalence of laboratory cr...

journal_title：Lung

authors： Barac A,Karimzadeh-Esfahani H,Pourostadi M,Rahimi MT,Ahmadpour E,Rashedi J,Mahdavipoor B,Kafil HS,Spotin A,Abate KH,Mathioudakis AG,Asgharzadeh M

更新日期：2019-10-01 00:00:00

abstract：:Gastro-oesophageal reflux disease (GORD) is generally considered one of the three main causes of chronic cough, along with asthma and nasal disease. The diagnosis of GORD is often based upon a successful trial of anti-acid treatment however GORD is a complex condition taking many forms. Only recently have studies star...

journal_title：Lung

authors： Smith J,Woodcock A,Houghton L

更新日期：2010-01-01 00:00:00

abstract：:Diffuse alveolar damage is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). A significant proportion of ARDS survivors have residual pulmonary fibrosis and compromised pulmonary function. On the other hand, heat shock protein 47 (HSP47) is a collagen-binding stress protein that is assumed to...

journal_title：Lung

authors： Hagiwara S,Iwasaka H,Matsumoto S,Noguchi T,Yoshioka H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Asbestos is a carcinogen linked to malignant mesothelioma (MM) and lung cancer. Some gene aberrations related to asbestos exposure are recognized, but many associated mutations remain obscure. We performed exome sequencing to determine the association of previously known mutations (driver gene mutations) wit...

journal_title：Lung

authors： Mäki-Nevala S,Sarhadi VK,Knuuttila A,Scheinin I,Ellonen P,Lagström S,Rönty M,Kettunen E,Husgafvel-Pursiainen K,Wolff H,Knuutila S

更新日期：2016-02-01 00:00:00

abstract：:Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...

journal_title：Lung

authors： Muyal JP,Muyal V,Kotnala S,Kumar D,Bhardwaj H

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:High concentrations of tumor necrosis factor-a (TNF), as well as excess of polymorphonuclear leukocytes (PMNs), are present in pleural fluid of patients with complicated parapneumonic effusion (CPPE). Several studies have shown that PMNs are capable of secreting TNF. However, the correlation between levels of TNF and ...

journal_title：Lung

authors： Odeh M,Sabo E,Srugo I,Oliven A

更新日期：2002-01-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The change in vital capacity from the seated to supine position (∆VC-supine) is used to screen for diaphragm dysfunction (DD), but some individuals are unable to tolerate the supine position. Since expiratory muscle function is often preserved in patients with isolated DD and inspiratory strength is reduced, th...

journal_title：Lung

authors： Koo P,Oyieng'o DO,Gartman EJ,Sethi JM,Eaton CB,McCool FD

更新日期：2017-02-01 00:00:00

abstract：:To determine whether changes in breathing pattern alone affect respiratory heat loss (RHL) and the constrictor response to cold dry gas hyperpnea in asthmatic subjects, we performed the following 2 part study: first we measured RHL in 8 asthmatic and 8 normal subjects during controlled eucapnic hyperpnea while they br...

journal_title：Lung

authors： Ingenito EP,Pichurko BM,Lafleur J,Drazen JM,Ingram RH Jr,Solway J

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:According to the National Family Health Survey, asthma is one of the leading diseases in India. In order to understand the complexity of asthma, the susceptibility genes need to be targeted for their association. Glutathione S-transferases play a major role in the detoxification of metabolites of oxidative s...

journal_title：Lung

authors： Birbian N,Singh J,Jindal SK,Joshi A,Batra N,Singla N

更新日期：2012-10-01 00:00:00

abstract：:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...

journal_title：Lung

authors： Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

更新日期：2018-12-01 00:00:00

abstract：:The lung has only a limited pattern of response to injury. Idiopathic interstitial fibrosis is a descriptive term, describing the end stage of one pattern of pulmonary fibrosis in which the inflammation lies within the structure of the alveolar walls and around vessels and bronchioli, in the interstitium. The disease ...

journal_title：Lung

authors： Lambe D

更新日期：1990-01-01 00:00:00

abstract：:Occupational exposure to oyster mushroom (Pleurotus ostreatus) has been associated with obstructive lung disease. Previously, we studied an extract of oyster mushroom (OME) and determined that it causes dose-dependent contractions of nonsensitized guinea pig trachea (GPT). We extend these studies to the investigation ...

journal_title：Lung

authors： Schachter EN,Zuskin E,Pucarin-Cvetkovic J,Chiarelli A,Goswami S

更新日期：2011-08-01 00:00:00

abstract：:We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...

journal_title：Lung

authors： Sagawa T,Kida T,Inaba T,Yokota I,Sagawa R,Kasahara A,Kaneshita S,Inoue T,Nagahara H,Fujioka K,Wada M,Kohno M,Kawahito Y

更新日期：2019-08-01 00:00:00

abstract：:Bronchiectasis is characterized by deregulated inflammatory response and recurrent bacterial infection resulting in progressive lung damage and an irreversible dilatation of bronchi and bronchioles. Generally accepted model of the development of bronchiectasis is the "vicious cycle hypothesis" that proposes compromisi...

journal_title：Lung

authors： Nikolic A

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Histological subdivision into typical (TC) and atypical (AC) is crucial for treatment and prognosis of lung carcinoids but can be also very challenging, even for experts. In this study, we aimed to strengthen or reduce the prognostic value of several pathological, clinical, or per-operative factors some of w...

journal_title：Lung

authors： Cusumano G,Fournel L,Strano S,Damotte D,Charpentier MC,Galia A,Terminella A,Nicolosi M,Regnard JF,Alifano M

更新日期：2017-12-01 00:00:00

abstract：:A 41-year-old woman presented with chest pain and a cough. There was a solitary pulmonary nodule in the upper-left lobe. The patient had no history of neoplasm except a hysterectomy for uterine leiomyoma five years before. Six months after the first presentation, the tumor showed a gradual increase in size; an explora...

journal_title：Lung

authors： Sapmaz F,Ergin M,Katrancioglu O,Gonlugur T,Gonlugur U,Elagoz S

更新日期：2008-07-01 00:00:00

abstract：:Along with upper airway cough syndrome (formerly, postnasal drip syndrome) and eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), gastroesophageal reflux disease (GERD) is generally considered among the most common etiologies of chronic cough. Indeed, cough management guidelines published...

journal_title：Lung

authors： Kahrilas PJ,Smith JA,Dicpinigaitis PV

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (NO) levels have been reported to be lower in patients with cystic fibrosis (CF) than in controls; however the mechanism(s) responsible and the effect on pathogenesis are unclear. The objective of these studies was to determine if the low levels of gas phase NO (gNO) could be reproduced ...

journal_title：Lung

authors： Ostrowski LE,Stewart D,Hazucha M

更新日期：2012-10-01 00:00:00

abstract：:Eosinophilic bronchitis is an essential component of bronchial asthma, and eosinophils play an important role. We studied the effect of eosinophils on cell surface plasmin generation by bronchial epithelial cells, because plasmin is thought to be involved in bronchial tissue repair/remodeling by means of fibrinolysis ...

journal_title：Lung

authors： Hara K,Hasegawa T,Ooi H,Koya T,Tanabe Y,Tsukada H,Igarashi K,Suzuki E,Arakawa M,Gejyo F

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:This is a meta-analysis of the safety and efficacy of indacaterol in chronic obstructive pulmonary disease (COPD) with treatment duration of ≥12 weeks. METHODS:Randomized controlled trials (RCTs) reported in English (to September 30, 2012) were identified from PubMed, the Cochrane Library, Embase, websites,...

journal_title：Lung

authors： Jiang FM,Liang ZA,Zheng QL,Wang RC,Luo J,Li CT

更新日期：2013-04-01 00:00:00

abstract：:The practice of sedation dosing strategy in mechanically ventilated patient has a profound effect on cognitive function. We conducted a comprehensive review of outcome of sedation on mental health function in critically ill patients on mechanical ventilation in the intensive care unit (ICU). We specifically evaluated ...

journal_title：Lung

authors： Porhomayon J,El-Solh AA,Adlparvar G,Jaoude P,Nader ND

更新日期：2016-02-01 00:00:00

abstract：:Cessation of smoking in the home is one of the most important nonpharmacologic actions to be recommended. There is a highly significant increase in wheezing, coughing, and respiratory infections in children with smoking mothers, and this increase is directly proportional to the number of cigarettes smoked. Cord blood ...

journal_title：Lung

authors： Price JA

更新日期：1990-01-01 00:00:00

abstract：:Cancer-testis antigens (CTAs) are expressed only in many cancers and limited immunoprivileged sites such as the testis and placenta. Dendritic cells (DCs) and CD8+ T lymphocytes (CTLs) play roles in the immune responses to tumor growth and may affect the prognosis of cancers. This study was designed to investigate the...

journal_title：Lung

authors： Kim SH,Lee S,Lee CH,Lee MK,Kim YD,Shin DH,Choi KU,Kim JY,Park DY,Sol MY

更新日期：2009-11-01 00:00:00

abstract：:Patients with untreated obstructive sleep apnea hypopnea (OSAH) are predisposed to developing hypertension, and therapy with continuous positive airway pressure (CPAP) may reduce blood pressure (BP). The purpose of this study was to assess the impact of CPAP therapy on BP in patients with OSAH. We performed a comprehe...

journal_title：Lung

authors： Alajmi M,Mulgrew AT,Fox J,Davidson W,Schulzer M,Mak E,Ryan CF,Fleetham J,Choi P,Ayas NT

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Pulmonary endarterectomy is the treatment of choice in chronic thromboembolic pulmonary hypertension (CTEPH). Modern pulmonary vasoactive medication (like endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, and prostacyclins) is used in patients with an inoperable disease and improved progn...

journal_title：Lung

authors： Scholzel BE,Post MC,Thijs Plokker HW,Snijder RJ

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...

journal_title：Lung

authors： Ramos-Casals M,Kostov B,Brito-Zerón P,Sisó-Almirall A,Baughman RP,Autoimmune Big Data Study Group.

更新日期：2019-08-01 00:00:00