Fcγ receptor IIIb (CD16b) polymorphisms are associated with susceptibility to idiopathic pulmonary fibrosis.

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and ran...

journal_title：Lung

authors： Abu-Hijleh M,Lee D,Braman SS

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Microbiological cultures are the mainstay of the diagnosis of tuberculosis (TB). False-positive TB results lead to significant unnecessary therapeutic and economic burden and are frequently caused by laboratory cross-contamination. The aim of this meta-analysis was to quantify the prevalence of laboratory cr...

journal_title：Lung

authors： Barac A,Karimzadeh-Esfahani H,Pourostadi M,Rahimi MT,Ahmadpour E,Rashedi J,Mahdavipoor B,Kafil HS,Spotin A,Abate KH,Mathioudakis AG,Asgharzadeh M

更新日期：2019-10-01 00:00:00

abstract：:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...

journal_title：Lung

authors： Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

更新日期：2018-12-01 00:00:00

abstract：:Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...

journal_title：Lung

authors： Muyal JP,Muyal V,Kotnala S,Kumar D,Bhardwaj H

更新日期：2013-04-01 00:00:00

abstract：:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is recognized as a preneoplastic condition by the World Health Organization. We reviewed our experience with 30 patients and performed a systematic review of the English literature to collect best evidence on the clinical features and disease cours...

journal_title：Lung

authors： Wirtschafter E,Walts AE,Liu ST,Marchevsky AM

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Several clinical trials of chemotherapy for non-small-cell lung cancer (NSCLC) have been conducted to date. However, these studies have not been effective at identifying category 1 recommended strategies for systemic chemotherapy according to the National Comprehensive Cancer Network clinical practice guidel...

journal_title：Lung

authors： Inoue K,Narukawa M,Takeuchi M

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:The relationship between asthma and obesity is well established, although the pathophysiological mechanisms linking both diseases remain unknown. Adiponectin is a hormone secreted by adipose cells, plays a role in the modulation of inflammation and may be the key linking these two types of inflammation. METHOD...

journal_title：Lung

authors： de Lima Azambuja R,da Costa Santos Azambuja LS,Costa C,Rufino R

更新日期：2015-10-01 00:00:00

abstract：:The effects of a pulmonary rehabilitation program on 44 patients with chronic obstructive pulmonary disease (COPD) were compared to a control group. The treated group was admitted to the program for a period of three months. The program consisted of several parts, such as physical training, health education, and psych...

journal_title：Lung

authors： Cox NJ,Hendricks JC,Binkhorst RA,van Herwaarden CL

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...

journal_title：Lung

authors： Hong ZY,Lee CG,Shim HS,Lee EJ,Song KH,Choi BW,Cho J,Story MD

更新日期：2016-02-01 00:00:00

abstract：:Diffuse alveolar damage is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). A significant proportion of ARDS survivors have residual pulmonary fibrosis and compromised pulmonary function. On the other hand, heat shock protein 47 (HSP47) is a collagen-binding stress protein that is assumed to...

journal_title：Lung

authors： Hagiwara S,Iwasaka H,Matsumoto S,Noguchi T,Yoshioka H

更新日期：2007-01-01 00:00:00

abstract：:A 15-year-old male had a history of increasing dyspnea on exertion, cough, sputum production, fever, weakness, hemoptysis, and diarrhea. Chest radiography demonstrated bilateral alveolar consolidation. Bronchoalveolar lavage fluid analysis revealed extensive hemosiderin-laden alveolar macrophages. On the basis of iron...

journal_title：Lung

authors： Hoca NT,Dayioglu D,Ogretensoy M

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To investigate whether lung function, especially when complicated with SDB, has an increased risk for myocardial infarction (MI) and congestive heart failure (CHF). METHODS:A prospective study was performed within the Sleep Heart Health Study (SHHS). A total of 4161 individuals were followed up for an average ...

journal_title：Lung

authors： Li R,Zhang J,Gao Y,Li J,Yan B,Wang G

更新日期：2019-06-01 00:00:00

abstract：:The role of leukotrienes in hypoxic vasoconstriction remains controversial. Our previous study using the lipoxygenase inhibitor BW 755C in dogs failed to show a substantive role for leukotrienes in hypoxic vasoconstriction. To clarify further the role of leukotrienes, we designed 3 protocols. In the first protocol, we...

journal_title：Lung

authors： Thomas HM 3rd,Sourour MS,Lopez D,Foster SH

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Sildenafil was the only phosphodiesterase-5 inhibitor available for the treatment of pulmonary arterial hypertension (PAH) until the approval and availability of once-daily tadalafil. Since no direct comparative study is likely to be performed between these agents, we sought to evaluate the feasibility of tr...

journal_title：Lung

authors： Shlobin OA,Brown AW,Weir N,Ahmad S,Lemma M,Nathan SD

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Depression is an important comorbidity for patients with chronic obstructive pulmonary disease (COPD). The association between depression and acute exacerbations of COPD is unknown. This study was designed to determine the frequency of COPD exacerbations in outpatients with and without depressive symptoms. ...

journal_title：Lung

authors： Jennings JH,Digiovine B,Obeid D,Frank C

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：:Cardiothoracic surgery posits an arrangement of large, significant hemodynamic, and physiologic alterations upon the human body, which predisposes a patient to develop pathology. The care of these patients in the postoperative realm requires an astute physician with deep understanding of the cardiopulmonary system, wh...

journal_title：Lung

authors： Tanner TG,Colvin MO

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Lung cancer is the leading cause of cancer death in the USA, claiming more than 140,000 deaths annually. Delays in diagnosis and treatment can lead to missed opportunities for both curative and life prolonging therapies. This study aimed to evaluate duration of time to diagnosis and first treatment, as wel...

journal_title：Lung

authors： Albano D,Bilfinger T,Feraca M,Kuperberg S,Nemesure B

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:Bronchopleural (BPF) and alveolar-pleural (APF) fistulas are frequently encountered in clinical practice with persistent air leaks that can lead to significant morbidity, prolonged hospital stay, and potentially increased mortality. BPF and APF are commonly related to pulmonary resections. Other etiologies include min...

journal_title：Lung

authors： Abu-Hijleh M,Blundin M

更新日期：2010-06-01 00:00:00

abstract：:The aim of our study was to evaluate clinical diagnoses in symptomatic persons exposed to aerosols from humidifiers or air conditioners. In addition, we tried to identify the causative antigens. Results of clinical investigations, including inhalation challenge tests, demonstrated a typical hypersensitivity pneumoniti...

journal_title：Lung

authors： Baur X,Behr J,Dewair M,Ehret W,Fruhmann G,Vogelmeier C,Weiss W,Zinkernagel V

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:The cardinal symptom of pulmonary hypertension (PH) is dyspnea on exertion, leading to decreased activity in daily living. The aim of this study was to analyze daily physical activity in incident patients with arterial or chronic thromboembolic PH (PAH/CTEPH) and to investigate its correlation with pulmona...

journal_title：Lung

authors： Saxer S,Lichtblau M,Berlier C,Hasler ED,Schwarz EI,Ulrich S

更新日期：2019-10-01 00:00:00

abstract：:The contribution of T-cells after lung transplant (LTx) remains controversial with no current consensus of their role concerning chronic lung allograft dysfunction. Using flow cytometry to assess T-cell subsets of bronchoalveolar lavage fluid (BALF) in 16 cystic fibrosis (CF) LTx recipients, we identified a decline in...

journal_title：Lung

authors： Hayes D Jr,Harhay MO,Nicol KK,Liyanage NPM,Keller BC,Robinson RT

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal fibrosing lung disease with a median survival of approximately 3 years after diagnosis. The only medical option to improve survival in IPF is lung transplantation (LTX). The purpose of this study was to evaluate trajectory data of IPF patients...

journal_title：Lung

authors： ten Klooster L,Nossent GD,Kwakkel-van Erp JM,van Kessel DA,Oudijk EJ,van de Graaf EA,Luijk B,Hoek RA,van den Blink B,van Hal PT,Verschuuren EA,van der Bij W,van Moorsel CH,Grutters JC

更新日期：2015-12-01 00:00:00

abstract：:The normal balance between coagulation and fibrinolysis in the pleural cavity is poorly understood despite the critical role of the pleura in the movement of the lungs. To determine the fibrinolytic activity and the interaction between plasminogen activators and their inhibitors in the normal pleural space, we tested ...

journal_title：Lung

authors： Li XY,Brown GM,Lamb D,Donaldson K

更新日期：1990-01-01 00:00:00

abstract：:Reaginic antibodies in hay fever patients belong to IgE. The immunoglobulin sensitizes basophilic granulocytes and mast cells from homologous species and mediates the release of chemical mediators which cause allergic symptoms. The sensitization is due to the binding of IgE to receptors on the target cells through the...

journal_title：Lung

authors： Ishizaka K,Ishizaka T

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Patients with various chronic respiratory diseases have a higher incidence of gastroesophageal reflux disease (GERD)-related symptoms, but the mechanisms of the relationship between GERD symptoms and chronic obstructive pulmonary disease (COPD) remain unclear. The aim of the present study was to explore the ...

journal_title：Lung

authors： Liang BM,Feng YL

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Restoring the barrier integrity of the alveolar epithelium after injury is pivotal. In the current study, we evaluated the effects of surfactant, surfactant protein A (SP-A), transforming growth factor β (TGF-β), and analogues of SP-A on alveolar epithelial repair. Additionally, we assessed the influence of mic...

journal_title：Lung

authors： Willems CH,Zimmermann LJ,Langen RM,van den Bosch MJ,Kloosterboer N,Kramer BW,van Iwaarden JF

更新日期：2012-12-01 00:00:00

abstract：:We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...

journal_title：Lung

authors： Sagawa T,Kida T,Inaba T,Yokota I,Sagawa R,Kasahara A,Kaneshita S,Inoue T,Nagahara H,Fujioka K,Wada M,Kohno M,Kawahito Y

更新日期：2019-08-01 00:00:00

abstract：:Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...

journal_title：Lung

authors： Bohadana AB,Michaely JP

更新日期：2006-05-01 00:00:00