Ischiocrural Strength May Be a Better Prognostic Marker Than Quadriceps Strength in COPD.

Abstract:

:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortality in COPD. We present the results of a retrospective study with longitudinal follow-up of 60 patients with severe COPD followed for 7 years. During follow-up 22 patients died, mainly of respiratory cause. We have observed that the strength of knee flexor muscles (ischiocrural) and dominant handgrip were independent predictors of mortality in severe COPD patients. However, knee extensor strength (quadriceps) was not an independent predictor of mortality. This is the first study which highlights the importance of knee flexor musculature as a prognostic factor in COPD.

journal_name

Lung

journal_title

Lung

authors

Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

doi

10.1007/s00408-018-0164-0

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

665-668

issue

6

eissn

0341-2040

issn

1432-1750

pii

10.1007/s00408-018-0164-0

journal_volume

196

pub_type

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