Treatment of atopic cough caused by Basidiomycetes antigen with low-dose itraconazol.

abstract：:Eosinophilic bronchitis is an essential component of bronchial asthma, and eosinophils play an important role. We studied the effect of eosinophils on cell surface plasmin generation by bronchial epithelial cells, because plasmin is thought to be involved in bronchial tissue repair/remodeling by means of fibrinolysis ...

journal_title：Lung

authors： Hara K,Hasegawa T,Ooi H,Koya T,Tanabe Y,Tsukada H,Igarashi K,Suzuki E,Arakawa M,Gejyo F

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Up to 50% of patients suffer short-term postoperative adverse events (AEs) and metastatic recurrence in the long-term following curative-intent lung cancer resection. The association between AEs, particularly infectious in nature, and disease recurrence is controversial. We sought to evaluate the association...

journal_title：Lung

authors： Gowing S,Baker L,Tran A,Zhang Z,Ahn H,Ivanovic J,Anstee C,Grigor E,Gilbert S,Maziak DE,Shamji F,Sundaresan S,Villeneuve PJ,Seely AJE

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To explore the role of CARM1 in lung cancer (LC) and its relationship with TP53 and CTNNB1. METHODS:Lung cells H1299 and PC14 were randomly divided into six groups: ov-H1299, si-H1299, ov-PC14, si-PC14, Con-H1299, and Con-PC14. Transwell assay, plate clone formation assay, and flow cytometry were used to det...

journal_title：Lung

authors： Hu B,Li X,Chen L,Liu Z

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:The change in vital capacity from the seated to supine position (∆VC-supine) is used to screen for diaphragm dysfunction (DD), but some individuals are unable to tolerate the supine position. Since expiratory muscle function is often preserved in patients with isolated DD and inspiratory strength is reduced, th...

journal_title：Lung

authors： Koo P,Oyieng'o DO,Gartman EJ,Sethi JM,Eaton CB,McCool FD

更新日期：2017-02-01 00:00:00

abstract：:The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...

journal_title：Lung

authors： Lai-Fook SJ

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:In obstructive sleep apnea (OSA), hypoxia secondary to apnea and hypopnea and the resulting systemic inflammatory response are the main causes of comorbidities. The aim of this study was to investigate the relationship between OSA and vimentin, which plays an important role in the activation of cells that synth...

journal_title：Lung

authors： Kerget B,Afşin DE,Kerget F,Aşkın S,Araz Ö,Akgün M

更新日期：2020-04-01 00:00:00

abstract：:Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...

journal_title：Lung

authors： Barreiro TJ,Gemmel D

更新日期：2014-10-01 00:00:00

abstract：:The author reviews the early history of alpha 1-antitrypsin (AAT) deficiency; the biochemical characterization of this inborn error of metabolism, its pattern of inheritance, frequency and predisposition to early, panacinar emphysema. The importance of the destructive element in emphysema and the gradual focusing on n...

journal_title：Lung

authors： Eriksson S

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Idiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies to alveolar epithelial and endothelial cells may be involved in the p...

journal_title：Lung

authors： Fahim A,Chong MC,Crooks MG,Hart SP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The aims of this study were to determine the incidence of tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease in patients who were treated with tumor necrosis factor (TNF) antagonists in South Korea and to evaluate their clinical characteristics. METHODS:We surveyed all patients (N = 509) w...

journal_title：Lung

authors： Lee SK,Kim SY,Kim EY,Jung JY,Park MS,Kim YS,Kim SK,Chang J,Kang YA

更新日期：2013-10-01 00:00:00

abstract：:Albumin diffusion measured in an isolated segment of rabbit lung interstitium with a radioactive tracer ((125)I-albumin) technique was independent of albumin concentration and similar to the free diffusion of albumin in water (Qiu et al, 1998. J Appl Physiol 85: 575-583). We studied the effect of hyaluronidase on the ...

journal_title：Lung

authors： Qiu XL,Brown LV,Parameswaran S,Marek VW,Ibbott GS,Lai-Fook SJ

更新日期：1999-01-01 00:00:00

abstract：:The effect of beta 2-adrenoceptor agonists on airway smooth muscle relaxation may be subject to desensitization. It could be modified by glucocorticosteroid treatment. An increase in the beta 2 agonist response by glucocorticosteroids in vitro has been described. We studied the effects of acute and chronic treatment w...

journal_title：Lung

authors： Seco AJ,Salgueiro ME,Manso G

更新日期：1995-01-01 00:00:00

abstract：:Electronic noses (e-noses) are based on arrays of different sensor types that respond to specific features of an odorant molecule, mostly volatile organic compounds (VOCs). Differently from gas chromatography and mass spectrometry, e-noses can distinguish VOCs spectrum by pattern recognition. E-nose technology has suc...

journal_title：Lung

authors： Dragonieri S,Pennazza G,Carratu P,Resta O

更新日期：2017-04-01 00:00:00

abstract：:Endobronchial Nd:Yag laser therapy is an excellent tool to reopen the central airway(s) in patients with severe respiratory symptoms caused by endobronchial tumor growth. Rigid bronchoscopy should be the method of choice. Usually general anesthesia is necessary. Complication rate depends on the condition of the patien...

journal_title：Lung

authors： Vanderschueren RG,Westermann CJ

更新日期：1990-01-01 00:00:00

abstract：:It is well established that cotton dust inhalation can compromise lung function in textile workers. Challenges with a water-soluble extract of cotton bract (CBE) can also induce reversible airway obstruction in healthy volunteers. We have examined the effect of inhaled CBE in nonhuman primates and have attempted to in...

journal_title：Lung

authors： Witek TJ Jr,Gundel RH,Wegner CD,Schachter EN,Buck MG

更新日期：1988-01-01 00:00:00

abstract：:Although the relative effect of racemic and (R)-albuterol on airway smooth muscle tone have been investigated in patients with airflow obstruction, the comparative effectiveness of these drugs in relaxing airway vascular smooth muscle is unknown. Therefore, we determined the actions of inhaled racemic and (R)-albutero...

journal_title：Lung

authors： Pereira A,Mendes E,Ferreira T,Wanner A

更新日期：2003-01-01 00:00:00

abstract：:Patients with pleural effusions frequently present a diagnostic and therapeutic challenge. The diagnosis is based on the interpretation of the results of thoracentesis or pleural biopsy. When a malignant tumor metastasizes to the pleura, tumor cells can be seeded over the mesothelial surface or in the subserous layer....

journal_title：Lung

authors： Mohamed KH,Mobasher AA,Yousef AI,Salah A,Ramadan MA,Emam AK,Alhayawan HM,Light RW

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:We investigated outcomes of patients hospitalized with community-acquired pneumonia (CAP) according to the changes in red cell distribution width (RDW). METHODS:For 980 adults, clinical characteristics, outcomes during hospitalization for CAP (transfer to the intensive care unit, treatment with mechanical vent...

journal_title：Lung

authors： Gorelik O,Izhakian S,Barchel D,Almoznino-Sarafian D,Tzur I,Swarka M,Beberashvili I,Feldman L,Cohen N,Shteinshnaider M

更新日期：2016-12-01 00:00:00

abstract：:Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...

journal_title：Lung

authors： Fujimoto K,Tsunoda T,Koizumi T,Kubo K

更新日期：2002-01-01 00:00:00

abstract：:Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...

journal_title：Lung

authors： Muyal JP,Muyal V,Kotnala S,Kumar D,Bhardwaj H

更新日期：2013-04-01 00:00:00

abstract：:Models of pulmonary edema have been used to study the nuclear magnetic resonance (NMR) characteristics of lung water. Several investigators have measured changes in the relaxation times in the permeability type of pulmonary edema, but relatively few have measured relaxation times in the hydrostatic type of pulmonary e...

journal_title：Lung

authors： Shioya S,Tsuji C,Haida M,Fukuzaki M,Tanigaki T,Kurita D,Ohta Y,Yamabayashi H

更新日期：1996-01-01 00:00:00

abstract：RATIONALE:The clinical characteristics and prognostic impact of radiographic patterns of patients with nontuberculous mycobacterial lung disease (NTM-LD) are rarely evaluated. DESIGN:Patients with NTM-LD from 2007 to 2009 in a single medical center in Taiwan were identified. Their radiographic patterns were reviewed a...

journal_title：Lung

authors： Shu CC,Lee CH,Hsu CL,Wang JT,Wang JY,Yu CJ,Lee LN,TAMI Group.

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:Bronchial provocation studies performed in our research center have consistently demonstrated airway hyperresponsiveness to both inhaled methacholine and histamine in subjects with chronic cervical spinal cord injury (SCI). More recently, we reported that the airways of such subjects maintained on chronic baclofen (ga...

journal_title：Lung

authors： Grimm DR,DeLuca RV,Lesser M,Bauman WA,Almenoff PL

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Pulmonary endarterectomy is the treatment of choice in chronic thromboembolic pulmonary hypertension (CTEPH). Modern pulmonary vasoactive medication (like endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, and prostacyclins) is used in patients with an inoperable disease and improved progn...

journal_title：Lung

authors： Scholzel BE,Post MC,Thijs Plokker HW,Snijder RJ

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:This is a meta-analysis of the safety and efficacy of indacaterol in chronic obstructive pulmonary disease (COPD) with treatment duration of ≥12 weeks. METHODS:Randomized controlled trials (RCTs) reported in English (to September 30, 2012) were identified from PubMed, the Cochrane Library, Embase, websites,...

journal_title：Lung

authors： Jiang FM,Liang ZA,Zheng QL,Wang RC,Luo J,Li CT

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Asthmatics are adversely affected by the presence of air pollutants, the concentrations of which can nowadays be measured. However, the utility of this information in clinical practice has not been defined in a group of asthmatics in stable condition. Our objective was to determine what impact the level of air ...

journal_title：Lung

authors： Fernandez R,Ariza M,Iscar M,Martinez C,Rubinos G,Gagatek S,Montoliu MA,Casan P

更新日期：2015-04-01 00:00:00

abstract：:Respiratory virus infections leads to coughing, sneezing, and increases in reflex parasympathetic bronchoconstriction and secretions. These responses to viral infection are exclusively or largely secondary to changes in the function of the nervous system. For many with underlying airway pathologies such as asthma and ...

journal_title：Lung

authors： Zaccone EJ,Undem BJ

更新日期：2016-02-01 00:00:00

abstract：INTRODUCTION:The cardinal symptom of pulmonary hypertension (PH) is dyspnea on exertion, leading to decreased activity in daily living. The aim of this study was to analyze daily physical activity in incident patients with arterial or chronic thromboembolic PH (PAH/CTEPH) and to investigate its correlation with pulmona...

journal_title：Lung

authors： Saxer S,Lichtblau M,Berlier C,Hasler ED,Schwarz EI,Ulrich S

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the exposure to hyperbaric hyperoxia increased respiratory system elastance and both the "ohmic" and viscoelastic components of inspiratory resistances, probably because of increased oxygen tension toxic effects. We presently investigated the possible consequences of a single ...

journal_title：Lung

authors： Rubini A,Porzionato A,Sarasin G,Zara S,Macchi V,Camporesi E,Bosco G

更新日期：2014-08-01 00:00:00