Acute pulmonary response to cotton bract extract in monkeys: lung function and effects of mediator modifying compounds.

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：INTRODUCTION:The goal of our systematic review and meta-analysis is to examine the therapeutic effectiveness of bronchoscopic lung volume reduction (BLVR), and to compare it with medical management and lung volume reduction surgery. METHODS:Variables of interest were absolute change in FEV1, 6MWT, and SGRQ. Meta-analy...

journal_title：Lung

authors： Kumar A,Dy R,Singh K,Jeffery Mador M

更新日期：2017-02-01 00:00:00

abstract：:Simulation-based medical education has gained tremendous popularity over the past two decades. Driven by the patient safety movement, changes in the educational opportunities available to trainees and the rapidly evolving capabilities of computer technology, simulation-based medical education is now being used across ...

journal_title：Lung

authors： Lam G,Ayas NT,Griesdale DE,Peets AD

更新日期：2010-12-01 00:00:00

abstract：:Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...

journal_title：Lung

authors： Fujimoto K,Tsunoda T,Koizumi T,Kubo K

更新日期：2002-01-01 00:00:00

abstract：:Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...

journal_title：Lung

authors： Vantaggiato L,Perruzza M,Refini RM,Bergantini L,d'Alessandro M,Cameli P,Perruzza D,Bini L,Bargagli E,Landi C

更新日期：2020-10-01 00:00:00

abstract：:The lung has only a limited pattern of response to injury. Idiopathic interstitial fibrosis is a descriptive term, describing the end stage of one pattern of pulmonary fibrosis in which the inflammation lies within the structure of the alveolar walls and around vessels and bronchioli, in the interstitium. The disease ...

journal_title：Lung

authors： Lambe D

更新日期：1990-01-01 00:00:00

abstract：:We studied the influence of age on glutathione (GSH) content in the distal lung and the lung tissue of mice. From 1 to 28 months of age, the quantity of GSH and glutathione disulfide (GSSG) in bronchoalveolar lavage (BAL) fluid and in the lung tissue were determined. The GSH content in BAL fluid, which reflects the an...

journal_title：Lung

authors： Teramoto S,Fukuchi Y,Uejima Y,Teramoto K,Ito H,Orimo H

更新日期：1994-01-01 00:00:00

abstract：:Particulate matter less than PM(10) and aromatic chemicals formed during incomplete combustion of organic matter are major environmental pollutants because of their toxic potential. The present study reports on the respiratory morbidity pattern of people exposed to auto exhaust as a result of the traffic load consisti...

journal_title：Lung

authors： Chattopadhyay BP,Mukherjee A,Mukherjee K,Roychowdhury A

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a systemic granulomatous disease which predominantly affects the lungs, although granulomas can also involve all other organs, including the heart. Cardiac sarcoidosis (CS) may occur at any stage of the disease and may be the cause of sudden cardiac death, even in a previously asymptomatic p...

journal_title：Lung

authors： Martusewicz-Boros MM,Boros PW,Wiatr E,Kempisty A,Piotrowska-Kownacka D,Roszkowski-Śliż K

更新日期：2016-02-01 00:00:00

abstract：:Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for atherosclerosis and arterial thrombosis, which are associated with high cardiovascular (CV) morbidity and mortality. In studies performed in clinical populations with elevated CV event risk profiles, the occurrence of moderate to severe OSAS was...

journal_title：Lung

authors： Toraldo DM,Peverini F,De Benedetto M,De Nuccio F

更新日期：2013-02-01 00:00:00

abstract：:Treatment of allergic asthma with inhaled corticosteroids results in local down-regulation of proinflammatory cytokine synthesis and in marked decrease in tissue eosinophilia. Blood concentrations of inhaled corticosteroids, although significantly lower than those measured in the lung, may still have antiinflammatory ...

journal_title：Lung

authors： Lantero S,Oddera S,Silvestri M,Gonzalez Rodriguez R,Morelli MC,Rossi GA

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION:Bronchopleural fistula is a rare but potentially fatal complication of pulmonary resections and proper management is essential for its resolution. In this study, we analyzed the incidence of fistula after pulmonary resection and reported data about endoscopic and conservative treatments of this complicatio...

journal_title：Lung

authors： Fuso L,Varone F,Nachira D,Leli I,Salimbene I,Congedo MT,Margaritora S,Granone P

更新日期：2016-04-01 00:00:00

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and ran...

journal_title：Lung

authors： Abu-Hijleh M,Lee D,Braman SS

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Hypoxia has been implicated in the pathogenesis of many inflammatory and fibrotic lung diseases. The effect of hypoxia on epithelial junction protein expression is yet to be fully elucidated but evidence suggests a protective role for the hypoxia-inducible transcription factor HIF-1 in stabilising occludin...

journal_title：Lung

authors： Li L,Watson CJ,Dubourd M,Bruton A,Xu M,Cooke G,Baugh JA

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...

journal_title：Lung

authors： Myint ZW,McCormick J,Chauhan A,Behrens E,Anthony LB

更新日期：2018-10-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：:Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...

journal_title：Lung

authors： Stephens SE,Foley KL,Miller D,Bellinger CR

更新日期：2019-12-01 00:00:00

abstract：:Impaired phagocytosis of Pseudomonas aeruginosa was found in isolated monocytes of peripheral blood of cystic fibrosis patients, but not in their neutrophils, as reported some years ago. In the present study, we analysed the phagocytic capacity of peripheral blood neutrophils and monocytes of cystic fibrosis patients ...

journal_title：Lung

authors： Leuer L,Krill A,Wilkens H,Wagenpfeil G,Bischoff M,Meier C,Bals R,Tschernig T

更新日期：2020-02-01 00:00:00

abstract：:The effects of vitamin E deficiency on bleomycin (BLM)-induced pulmonary fibrosis have been studied by analyses of pressure volume (PV) curves and morphological examinations. Golden hamsters were divided into groups on a control diet (group C), vitamin E-deficient diet (E), control diet with BLM treatment (CB), and vi...

journal_title：Lung

authors： Nakamura H,Sato S,Takahashi K

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...

journal_title：Lung

authors： Hong ZY,Lee CG,Shim HS,Lee EJ,Song KH,Choi BW,Cho J,Story MD

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:This study was designed to review outcomes of once- (QD) versus twice-daily (BID) radiotherapy (RT) for limited stage small-cell lung cancer (L-SCLC) treated at Dana-Farber Cancer Institute/Brigham and Women's Hospital. METHODS:We reviewed records for all patients with L-SCLC treated with radical chemoradiothe...

journal_title：Lung

authors： Gazula A,Baldini EH,Chen A,Kozono D

更新日期：2014-02-01 00:00:00

abstract：:Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...

journal_title：Lung

authors： Hu Y,Peng J,Feng D,Chu L,Li X,Jin Z,Lin Z,Zeng Q

更新日期：2006-01-01 00:00:00

abstract：: ...

journal_title：Lung

authors： Adams TN,Newton CA,Glazer CS

更新日期：2019-02-01 00:00:00

abstract：:Bronchopleural (BPF) and alveolar-pleural (APF) fistulas are frequently encountered in clinical practice with persistent air leaks that can lead to significant morbidity, prolonged hospital stay, and potentially increased mortality. BPF and APF are commonly related to pulmonary resections. Other etiologies include min...

journal_title：Lung

authors： Abu-Hijleh M,Blundin M

更新日期：2010-06-01 00:00:00

abstract：:Endobronchial Nd:Yag laser therapy is an excellent tool to reopen the central airway(s) in patients with severe respiratory symptoms caused by endobronchial tumor growth. Rigid bronchoscopy should be the method of choice. Usually general anesthesia is necessary. Complication rate depends on the condition of the patien...

journal_title：Lung

authors： Vanderschueren RG,Westermann CJ

更新日期：1990-01-01 00:00:00

abstract：:The original version of this article contained an error in the usage of the term "false positive rate". The intention of the authors in those instances was simply to compare the absolute percentage of false positive results in the study vs the NLST, not to make any observations about false positive rate in the strict ...

journal_title：Lung

authors： Lam VK,Miller M,Dowling L,Singhal S,Young RP,Cabebe EC

更新日期：2019-10-01 00:00:00

abstract：:The influence of phospholipids on the ultrastructure and metabolism of reconstituted surfactants has not been well defined. The aim of this study was to determine if changes in the phospholipid composition of reconstituted surfactants altered their biophysical properties, ultrastructure, and conversion to light subtyp...

journal_title：Lung

authors： Dhand R,Young J,Krishnasamy S,Possmayer F,Gross NJ

更新日期：1999-01-01 00:00:00

abstract：:Alveolar epithelial type II (AT II) cells need phosphate (Pi) for surfactant synthesis. The Na-dependent (Na(d)) Pi transporters NaPi-IIb and Pit-1 are expressed in lung, but their expression, regulation, and function in AT II cells remain unclear. We studied NaPi-IIb and Pit-1 mRNA expression in cultured AT II cells ...

journal_title：Lung

authors： Jin C,Zoidis E,Ghirlanda C,Schmid C

更新日期：2010-01-01 00:00:00

abstract：:Undifferentiated connective tissue disease (UCTD) is a distinct clinical entity that may be accompanied by interstitial lung disease (ILD). The natural history of UCTD-ILD is unknown. We hypothesized that patients with UCTD-ILD would be more likely to have improvement in lung function than those with idiopathic pulmon...

journal_title：Lung

authors： Kinder BW,Shariat C,Collard HR,Koth LL,Wolters PJ,Golden JA,Panos RJ,King TE Jr

更新日期：2010-04-01 00:00:00

abstract：:A method has been developed for the isolation of bovine type II pneumocytes by enzymatic tissue dissociation and subsequent density gradient centrifugation. After mechanical defibrination, the crude cell suspension contains 71.9 +/- 26.6 X 10(7) cells (viability greater than 95%) with a type II cell purity of 39.4 +/-...

journal_title：Lung

authors： Augustin-Voss HG,Schoon HA,Stockhofe N,Ueberschär S

更新日期：1989-01-01 00:00:00