Emergency use of an endobronchial one-way valve in the management of severe air leak and massive subcutaneous emphysema.

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Cardiopulmonary exercise testing (CPET) is a safe and clinically useful method to assess functional capacity and to follow disease progression and the response to treatment in several clinical conditions. AIM:We set out to determine the relationship between outcome measures of CPET and high-resolution compu...

journal_title：Lung

authors： Lopes AJ,de Menezes SL,Dias CM,de Oliveira JF,Mainenti MR,Guimarães FS

更新日期：2011-10-01 00:00:00

abstract：:This study was designed to determine the effects of thromboxane A2 (TxA2) on the distribution of vascular resistance, lung weight, and microvascular permeability in isolated dog lungs perfused at a constant pressure with autologous blood. The stable TxA2 analogue (STA2; 30 micrograms, n = 5) caused an increase in pulm...

journal_title：Lung

authors： Shibamoto T,Wang HG,Yamaguchi Y,Hayashi T,Saeki Y,Tanaka S,Koyama S

更新日期：1995-01-01 00:00:00

abstract：:The contribution of T-cells after lung transplant (LTx) remains controversial with no current consensus of their role concerning chronic lung allograft dysfunction. Using flow cytometry to assess T-cell subsets of bronchoalveolar lavage fluid (BALF) in 16 cystic fibrosis (CF) LTx recipients, we identified a decline in...

journal_title：Lung

authors： Hayes D Jr,Harhay MO,Nicol KK,Liyanage NPM,Keller BC,Robinson RT

更新日期：2020-02-01 00:00:00

abstract：:Gastro-oesophageal reflux disease (GORD) is generally considered one of the three main causes of chronic cough, along with asthma and nasal disease. The diagnosis of GORD is often based upon a successful trial of anti-acid treatment however GORD is a complex condition taking many forms. Only recently have studies star...

journal_title：Lung

authors： Smith J,Woodcock A,Houghton L

更新日期：2010-01-01 00:00:00

abstract：:Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...

journal_title：Lung

authors： Barreiro TJ,Gemmel D

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:Endobronchial Nd:Yag laser therapy is an excellent tool to reopen the central airway(s) in patients with severe respiratory symptoms caused by endobronchial tumor growth. Rigid bronchoscopy should be the method of choice. Usually general anesthesia is necessary. Complication rate depends on the condition of the patien...

journal_title：Lung

authors： Vanderschueren RG,Westermann CJ

更新日期：1990-01-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to determine if electrocardiographically synchronized, prospectively triggered multidetector row computed tomography (ECG-MDR-CT) angiography of the aorta can accurately predict the location of ectopic bronchial arteries in patients with cystic fibrosis (CF) with massive hemop...

journal_title：Lung

authors： Hayes D Jr,Winkler MA,Kirkby S,Capasso P,Mansour HM,Attili AK

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Transbronchial lung biopsy (TBBX) is a common respiratory diagnostic procedure performed to investigate several lung diseases. There are different types of forceps used to perform this procedure. The alligator and cupped (oval) forceps are most commonly used ones. To date, there are few studies that have com...

journal_title：Lung

authors： Almadani A,Ping MNY,Deenadayalu A,Saunders J,O'Brien A

更新日期：2019-02-01 00:00:00

abstract：:Patients with untreated obstructive sleep apnea hypopnea (OSAH) are predisposed to developing hypertension, and therapy with continuous positive airway pressure (CPAP) may reduce blood pressure (BP). The purpose of this study was to assess the impact of CPAP therapy on BP in patients with OSAH. We performed a comprehe...

journal_title：Lung

authors： Alajmi M,Mulgrew AT,Fox J,Davidson W,Schulzer M,Mak E,Ryan CF,Fleetham J,Choi P,Ayas NT

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:Improving dyspnea and exercise performance are goals of COPD therapy. We tested the hypothesis that air current applied to the face would lessen dyspnea and improve exercise performance in moderate-severe COPD patients. METHODS:We recruited 10 COPD patients (5 men, age 62 ± 6 years, FEV1 0.93 ± 0.11 L (34 ± 3%...

journal_title：Lung

authors： Marchetti N,Lammi MR,Travaline JM,Ciccolella D,Civic B,Criner GJ

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Restoring the barrier integrity of the alveolar epithelium after injury is pivotal. In the current study, we evaluated the effects of surfactant, surfactant protein A (SP-A), transforming growth factor β (TGF-β), and analogues of SP-A on alveolar epithelial repair. Additionally, we assessed the influence of mic...

journal_title：Lung

authors： Willems CH,Zimmermann LJ,Langen RM,van den Bosch MJ,Kloosterboer N,Kramer BW,van Iwaarden JF

更新日期：2012-12-01 00:00:00

abstract：:Pleurodesis is a useful therapeutic tool when local treatment of a recurrent malignant pleural effusion or pneumothorax is needed. We have previously demonstrated that the intrapleural injection of 0.5% silver nitrate (SN) produces a significant pleurodesis, while 0.25% SN has no sclerosing effect in a rabbit model. T...

journal_title：Lung

authors： Teixeira LR,Vargas FS,Antonangelo L,Mattos VC,Vaz MA,Acencio MM,Marchi E

更新日期：2003-11-01 00:00:00

abstract：:It is well known that exposure to hyperoxia results in lung inflammation and damage, which leads to the development of chronic lung disease. Previous studies have shown increased activities of antioxidant enzymes (AOE) in lung tissue from animals exposed to hyperoxia. We propose the hypothesis that the fetal type II p...

journal_title：Lung

authors： Bhandari V,Maulik N,Kresch M

更新日期：2000-01-01 00:00:00

abstract：:We report two patients with atopic cough due to Basidiomycetes antigen. One patient was a 27 year-old woman and the other was a 17 year-old boy. Both patients visited our hospital because of severe nonproductive cough. They did not have bronchial hyperresponsiveness to methacholine or heightened bronchomotor tone. Bro...

journal_title：Lung

authors： Ogawa H,Fujimura M,Tofuku Y

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...

journal_title：Lung

authors： Hong ZY,Lee CG,Shim HS,Lee EJ,Song KH,Choi BW,Cho J,Story MD

更新日期：2016-02-01 00:00:00

abstract：:It is well established that cotton dust inhalation can compromise lung function in textile workers. Challenges with a water-soluble extract of cotton bract (CBE) can also induce reversible airway obstruction in healthy volunteers. We have examined the effect of inhaled CBE in nonhuman primates and have attempted to in...

journal_title：Lung

authors： Witek TJ Jr,Gundel RH,Wegner CD,Schachter EN,Buck MG

更新日期：1988-01-01 00:00:00

abstract：:In severe asthma attacks beta 2-sympathomimetics lose part of their therapeutic efficiency. To elucidate this loss of efficiency in an experimental model we compared the relaxant potency of salbutamol (SAL), fenoterol (FEN), formoterol (FOR), and (-)-isoprenaline (ISO) in guinea pig tracheae partially and maximally pr...

journal_title：Lung

authors： Lemoine H,Overlack C,Köhl A,Worth H,Reinhardt D

更新日期：1992-01-01 00:00:00

abstract：:An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may contribute to the pathogenesis of IPF. The neutrophil FcγRIIIb receptor occurs in two codominantly expressed allelic variants, NA1 and N...

journal_title：Lung

authors： Bournazos S,Bournazou I,Murchison JT,Wallace WA,McFarlane P,Hirani N,Simpson AJ,Dransfield I,Hart SP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Several clinical trials of chemotherapy for non-small-cell lung cancer (NSCLC) have been conducted to date. However, these studies have not been effective at identifying category 1 recommended strategies for systemic chemotherapy according to the National Comprehensive Cancer Network clinical practice guidel...

journal_title：Lung

authors： Inoue K,Narukawa M,Takeuchi M

更新日期：2012-08-01 00:00:00

abstract：:The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...

journal_title：Lung

authors： Nadal D,Ogra PL

更新日期：1990-01-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：INTRODUCTION:The goal of our systematic review and meta-analysis is to examine the therapeutic effectiveness of bronchoscopic lung volume reduction (BLVR), and to compare it with medical management and lung volume reduction surgery. METHODS:Variables of interest were absolute change in FEV1, 6MWT, and SGRQ. Meta-analy...

journal_title：Lung

authors： Kumar A,Dy R,Singh K,Jeffery Mador M

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:Flexible fiberoptic bronchoscopy (FFB) plays an important role in the surveillance of cystic fibrosis (CF) patients after lung transplantation (LTx). With rapid onset and clearance, propofol provides a safe and efficient method for sedation during FFB, yet sedation requirements for CF patients are not well...

journal_title：Lung

authors： Ho C,Hayes D Jr,Khosravi M,Splaingard ML,Tumin D,Lloyd EA

更新日期：2018-08-01 00:00:00

abstract：:Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...

journal_title：Lung

authors： Hu Y,Peng J,Feng D,Chu L,Li X,Jin Z,Lin Z,Zeng Q

更新日期：2006-01-01 00:00:00

abstract：:Cryoextraction is a procedure for recanalization of obstructed airways caused by exophytic growing tumors. Biopsy samples obtained with this method can be used for histological diagnosis. The objective of this study was to evaluate the parameters influencing the size of cryobiopsies in an in vitro animal model. New fl...

journal_title：Lung

authors： Franke KJ,Szyrach M,Nilius G,Hetzel J,Hetzel M,Ruehle KH,Enderle MD

更新日期：2009-08-01 00:00:00

abstract：:To explore further the possible etiologic role of mycobacteria in the development of sarcoidosis, we measured free, nonbound tuberculostearic acid (TSA, 10-methyloctadecanoic), a component of mycobacteria, in the sera of subjects with sarcoidosis or active untreated pulmonary tuberculosis and in healthy controls by us...

journal_title：Lung

authors： Almenoff PL,Brooks JB,Johnson A,Lesser M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Prolonged exposure to crystalline silica leads to persistent pulmonary inflammation and progressive fibrosis. Connective tissue growth factor (CTGF) has emerged as a potent proinflammatory and profibrotic regulator to participate in a variety of chronic inflammatory diseases. However, the role of CTGF in sil...

journal_title：Lung

authors： Zhou T,Yu Q,Lin H,Wang Z,Fu G,Lei L,Shi Y,Zhang L,Qin L,Liu Y

更新日期：2019-12-01 00:00:00

abstract：:The early pathogenic events in cystic fibrosis (CF) include colonization of Pseudomonas in the lung, airway inflammation, and mucus hypersecretion with airway obstruction. The primary mechanisms leading to chronic infection and inflammation are not well understood. One possible explanation for this cascade of events i...

journal_title：Lung

authors： Voynow JA,Selby DM,Rose MC

更新日期：1998-01-01 00:00:00