Sedation with Propofol for Bronchoscopy in Cystic Fibrosis Lung Transplant Recipients.

abstract：PURPOSE:This study was designed to review outcomes of once- (QD) versus twice-daily (BID) radiotherapy (RT) for limited stage small-cell lung cancer (L-SCLC) treated at Dana-Farber Cancer Institute/Brigham and Women's Hospital. METHODS:We reviewed records for all patients with L-SCLC treated with radical chemoradiothe...

journal_title：Lung

authors： Gazula A,Baldini EH,Chen A,Kozono D

更新日期：2014-02-01 00:00:00

abstract：:The contribution of T-cells after lung transplant (LTx) remains controversial with no current consensus of their role concerning chronic lung allograft dysfunction. Using flow cytometry to assess T-cell subsets of bronchoalveolar lavage fluid (BALF) in 16 cystic fibrosis (CF) LTx recipients, we identified a decline in...

journal_title：Lung

authors： Hayes D Jr,Harhay MO,Nicol KK,Liyanage NPM,Keller BC,Robinson RT

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:Driving pressure (DP) while on ECMO has been studied in acute respiratory distress syndrome (ARDS) but no studies exist in those on ECMO without ARDS. We aimed to study association of mortality with DP in all patients on ECMO and compare change in DP before and after initiation of ECMO. METHODS:Consecutiv...

journal_title：Lung

authors： Gupta E,Awsare B,Hirose H,Cavarocchi N,Baram M

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Tree-in-bud (TIB) is a radiologic pattern seen on high-resolution chest CT reflecting bronchiolar mucoid impaction occasionally with additional involvement of adjacent alveoli. Its microbiologic significance has not been systematically evaluated. OBJECTIVES:We aimed to establish the incidence of the TIB pat...

journal_title：Lung

authors： Shimon G,Yonit WW,Gabriel I,Naama BR,Nissim A

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Long Acting Beta2 Agonists (LABA) prevent COPD exacerbations in strictly standardized clinical trials. Our aim was to evaluate the relationship between the amount of LABA provided by the government and the trend in COPD hospital admission (HA) rate in Brazil. METHODS:This is a longitudinal large-scale real-lif...

journal_title：Lung

authors： Ponte EV,Cruz ÁA,Lima VB,Stelmach R,Viegi G

更新日期：2018-12-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Restoring the barrier integrity of the alveolar epithelium after injury is pivotal. In the current study, we evaluated the effects of surfactant, surfactant protein A (SP-A), transforming growth factor β (TGF-β), and analogues of SP-A on alveolar epithelial repair. Additionally, we assessed the influence of mic...

journal_title：Lung

authors： Willems CH,Zimmermann LJ,Langen RM,van den Bosch MJ,Kloosterboer N,Kramer BW,van Iwaarden JF

更新日期：2012-12-01 00:00:00

abstract：:Bronchopleural (BPF) and alveolar-pleural (APF) fistulas are frequently encountered in clinical practice with persistent air leaks that can lead to significant morbidity, prolonged hospital stay, and potentially increased mortality. BPF and APF are commonly related to pulmonary resections. Other etiologies include min...

journal_title：Lung

authors： Abu-Hijleh M,Blundin M

更新日期：2010-06-01 00:00:00

abstract：:The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of t...

journal_title：Lung

authors： Lee YK,Oh YM,Lee JH,Kim EK,Lee JH,Kim N,Seo JB,Lee SD,KOLD Study Group.

更新日期：2008-05-01 00:00:00

abstract：:Difficult weaning is fortunately a rare occurrence in mechanically ventilated patients in ICU. When faced with this problem, a vast number of factors must be carefully considered simultaneously: physiological adjustment, technical problems (tubing, circuit resistances, . . .) [13]. The most promising approach to diffi...

journal_title：Lung

authors： Chevrolet JC

更新日期：1990-01-01 00:00:00

abstract：:This study demonstrates for the first time that endothelial cells freshly isolated from small pulmonary arteries of the rat, based on their electrophysiological profile, possess two distinct populations of cells. Immunohistochemical staining revealed the presence of both anti-Kv1.5 and anti-Kir2.1 immunoreactivity in ...

journal_title：Lung

authors： Hogg DS,McMurray G,Kozlowski RZ

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue destruction and airflow limitation. Autophagy is a fundamental cellular process that eliminates long-lived proteins and damaged organelles through lysosom...

journal_title：Lung

authors： Li L,Zhang M,Zhang L,Cheng Y,Tu X,Lu Z

更新日期：2017-06-01 00:00:00

abstract：:Eosinophilic bronchitis is an essential component of bronchial asthma, and eosinophils play an important role. We studied the effect of eosinophils on cell surface plasmin generation by bronchial epithelial cells, because plasmin is thought to be involved in bronchial tissue repair/remodeling by means of fibrinolysis ...

journal_title：Lung

authors： Hara K,Hasegawa T,Ooi H,Koya T,Tanabe Y,Tsukada H,Igarashi K,Suzuki E,Arakawa M,Gejyo F

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:In obstructive sleep apnea (OSA), hypoxia secondary to apnea and hypopnea and the resulting systemic inflammatory response are the main causes of comorbidities. The aim of this study was to investigate the relationship between OSA and vimentin, which plays an important role in the activation of cells that synth...

journal_title：Lung

authors： Kerget B,Afşin DE,Kerget F,Aşkın S,Araz Ö,Akgün M

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...

journal_title：Lung

authors： Ramos-Casals M,Kostov B,Brito-Zerón P,Sisó-Almirall A,Baughman RP,Autoimmune Big Data Study Group.

更新日期：2019-08-01 00:00:00

abstract：:This study was designed to determine the effects of thromboxane A2 (TxA2) on the distribution of vascular resistance, lung weight, and microvascular permeability in isolated dog lungs perfused at a constant pressure with autologous blood. The stable TxA2 analogue (STA2; 30 micrograms, n = 5) caused an increase in pulm...

journal_title：Lung

authors： Shibamoto T,Wang HG,Yamaguchi Y,Hayashi T,Saeki Y,Tanaka S,Koyama S

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Malignant mesothelioma is an aggressive tumor of serosal surfaces that is closely associated with asbestos exposure which induces oxidative stress. Heme oxygenase (HO)-1, a rate-limiting enzyme of heme degradation, plays a protective role against oxidative stress. The HO-1 gene promoter carries (GT)n repeats...

journal_title：Lung

authors： Murakami A,Fujimori Y,Yoshikawa Y,Yamada S,Tamura K,Hirayama N,Terada T,Kuribayashi K,Tabata C,Fukuoka K,Tamaoki T,Nakano T

更新日期：2012-06-01 00:00:00

abstract：:Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...

journal_title：Lung

authors： Barreiro TJ,Gemmel D

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:According to the National Family Health Survey, asthma is one of the leading diseases in India. In order to understand the complexity of asthma, the susceptibility genes need to be targeted for their association. Glutathione S-transferases play a major role in the detoxification of metabolites of oxidative s...

journal_title：Lung

authors： Birbian N,Singh J,Jindal SK,Joshi A,Batra N,Singla N

更新日期：2012-10-01 00:00:00

abstract：:Isoniazid (INH) is one of the most important first line drugs in the treatment of tuberculosis. We utilized high performance liquid chromatography with a hydrazone extraction technique to measure INH in bronchoalveolar lavage (BAL) fluid specimens from six patients with active pulmonary tuberculosis. We found BAL flui...

journal_title：Lung

authors： O'Brien JK,Doerfler ME,Harkin TJ,Rom WN

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The right ventricular ejection fraction (RVEF) is a surrogate marker of right ventricular function in pulmonary hypertension (PH), but its measurement is complicated and time consuming. The tricuspid annular plane systolic excursion (TAPSE) measures only the longitudinal component of RV contraction while the...

journal_title：Lung

authors： Hoette S,Creuzé N,Günther S,Montani D,Savale L,Jaïs X,Parent F,Sitbon O,Rochitte CE,Simonneau G,Humbert M,Souza R,Chemla D

更新日期：2018-04-01 00:00:00

abstract：:Bradykinin (10(-8) - 10(-5) M) caused a concentration-dependent increase in cyclic GMP (cGMP) production in bovine tracheal smooth muscle in the absence of epithelium. The effect was calcium-dependent and was inhibited by pyrogallol (10 microM) and methylene blue (10 microM). The inhibition of pyrogallol was reversed ...

journal_title：Lung

authors： Sheng H,Ishii K,Förstermann U,Murad F

更新日期：1995-01-01 00:00:00

abstract：:Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...

journal_title：Lung

authors： Hu Y,Peng J,Feng D,Chu L,Li X,Jin Z,Lin Z,Zeng Q

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:Current guidelines recommend the use of low molecular weight heparin (LMWH) for most haemodynamically stable patients with pulmonary thromboembolism (PTE), however, it is not clear whether LMWH is preferable to unfractionated heparin (UFH) for the treatment of massive PTE. We aimed to compare the use of LMWH ve...

journal_title：Lung

authors： Ucar EY,Akgun M,Araz O,Tas H,Kerget B,Meral M,Kaynar H,Saglam L

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：:This study was designed to use volumetric capnography to evaluate the breathing pattern and ventilation inhomogeneities in patients with chronic sputum production and bronchiectasis and to correlate the phase 3 slope of the capnographic curve to spirometric measurements. Twenty-four patients with cystic fibrosis (CF) ...

journal_title：Lung

authors： Veronez L,Moreira MM,Soares ST,Pereira MC,Ribeiro MA,Ribeiro JD,Terzi RG,Martins LC,Paschoal IA

更新日期：2010-06-01 00:00:00

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...

journal_title：Lung

authors： Hong ZY,Lee CG,Shim HS,Lee EJ,Song KH,Choi BW,Cho J,Story MD

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Asbestos is a carcinogen linked to malignant mesothelioma (MM) and lung cancer. Some gene aberrations related to asbestos exposure are recognized, but many associated mutations remain obscure. We performed exome sequencing to determine the association of previously known mutations (driver gene mutations) wit...

journal_title：Lung

authors： Mäki-Nevala S,Sarhadi VK,Knuuttila A,Scheinin I,Ellonen P,Lagström S,Rönty M,Kettunen E,Husgafvel-Pursiainen K,Wolff H,Knuutila S

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...

journal_title：Lung

authors： Myint ZW,McCormick J,Chauhan A,Behrens E,Anthony LB

更新日期：2018-10-01 00:00:00