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LUNG文献大全abstract::In patients with congestive heart failure (CHF), a high prevalence of sleep-disordered breathing has been described. Cheyne-Stokes respiration (CSR) is present in up to 40% of patients with CHF. During the last decade, the medical treatment has been substantially improved. This study was designed to analyze the progno...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-009-9208-9
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:Exercising or doing physical activity in polluted air could expose a person to the adverse health effects of air pollution. This study aimed to compare the cardiovascular and hematologic indices following an incremental exercise test (shuttle run) under clean versus polluted air conditions. METHODS:Nineteen ma...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-014-9679-1
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Prophylactic continuous positive airway pressure (CPAP) can prevent pulmonary adverse events following upper abdominal surgeries. The present meta-regression evaluates and quantifies the effect of degree/duration of (CPAP) on the incidence of postoperative pulmonary events. METHODS:Medical databases were ...
journal_title:Lung
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00408-016-9855-6
更新日期:2016-04-01 00:00:00
abstract::Several pieces of evidence support the view that exudation of plasma into the airway wall and into the airway lumen occurs in asthma. Vascular leakage of plasma results from inflammatory mediator-induced separation of endothelial cells in postcapillary venules belonging to the tracheobronchial circulation. Whereas pro...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02714025
更新日期:1988-01-01 00:00:00
abstract::Patients with pleural effusions frequently present a diagnostic and therapeutic challenge. The diagnosis is based on the interpretation of the results of thoracentesis or pleural biopsy. When a malignant tumor metastasizes to the pleura, tumor cells can be seeded over the mesothelial surface or in the subserous layer....
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000040
更新日期:2000-11-01 00:00:00
abstract::Cancer-testis antigens (CTAs) are expressed only in many cancers and limited immunoprivileged sites such as the testis and placenta. Dendritic cells (DCs) and CD8+ T lymphocytes (CTLs) play roles in the immune responses to tumor growth and may affect the prognosis of cancers. This study was designed to investigate the...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-009-9181-3
更新日期:2009-11-01 00:00:00
abstract::High concentrations of tumor necrosis factor-a (TNF), as well as excess of polymorphonuclear leukocytes (PMNs), are present in pleural fluid of patients with complicated parapneumonic effusion (CPPE). Several studies have shown that PMNs are capable of secreting TNF. However, the correlation between levels of TNF and ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000100
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Up to 50% of patients suffer short-term postoperative adverse events (AEs) and metastatic recurrence in the long-term following curative-intent lung cancer resection. The association between AEs, particularly infectious in nature, and disease recurrence is controversial. We sought to evaluate the association...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00395-6
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:Traditional inflammatory biomarkers are insufficient for the evaluation of bronchiolitis severity. Recent investigations have shown that the receptor for advanced glycation end product (RAGE) and its soluble isoforms (sRAGE) play a critical role in the pathogenesis of lung injury. Main objective was to assess t...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-014-9663-9
更新日期:2015-02-01 00:00:00
abstract::This study was designed to determine the effects of thromboxane A2 (TxA2) on the distribution of vascular resistance, lung weight, and microvascular permeability in isolated dog lungs perfused at a constant pressure with autologous blood. The stable TxA2 analogue (STA2; 30 micrograms, n = 5) caused an increase in pulm...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00181873
更新日期:1995-01-01 00:00:00
abstract::Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2560-5
更新日期:2006-01-01 00:00:00
abstract::The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718155
更新日期:1990-01-01 00:00:00
abstract::The effect of tetraethylammonium (TEA) and K+ on contractions to histamine and acetylcholine have been compared in the pig isolated trachea using organ bath and sucrose-gap techniques. Histamine elicited weak contractions, compared with acetylcholine; however, these contractions were markedly potentiated by pretreatme...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF02714429
更新日期:1987-01-01 00:00:00
abstract::This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2569-9
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal fibrosing lung disease with a median survival of approximately 3 years after diagnosis. The only medical option to improve survival in IPF is lung transplantation (LTX). The purpose of this study was to evaluate trajectory data of IPF patients...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-015-9794-7
更新日期:2015-12-01 00:00:00
abstract::Along with upper airway cough syndrome (formerly, postnasal drip syndrome) and eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), gastroesophageal reflux disease (GERD) is generally considered among the most common etiologies of chronic cough. Indeed, cough management guidelines published...
journal_title:Lung
pub_type:
doi:10.1007/s00408-013-9528-7
更新日期:2014-02-01 00:00:00
abstract::The efficacy of the docetaxel-carboplatin combination chemotherapy was studied in various phase II studies. Based on these data we aimed to test the regimen in previously untreated patients with advanced advanced non-smoking lung cancer (NSCLC) with docetaxel 80 mg/m2 a standard dose of carboplatin at AUC = 5, in an a...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2552-5
更新日期:2005-11-01 00:00:00
abstract::The major goal of all diagnostic and therapeutic efforts in childhood asthma is to prevent progression of lung disease into adulthood. To improve the uncomfortable situation of underdiagnosis and undertreatment and to lower the risk of acquiring irreversible lung damage, an optimal co-working relationship between fami...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718166
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:We aimed to determine the time, dose, and volume responses in a mouse pulmonary injury model following ablative dose focal irradiation (ADFIR) in order to better understand normal lung injury. METHODS AND MATERIALS:ADFIR was administered to the left lung of mice using a small animal micro-irradiator. Histopath...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-015-9825-4
更新日期:2016-02-01 00:00:00
abstract::A 41-year-old woman presented with chest pain and a cough. There was a solitary pulmonary nodule in the upper-left lobe. The patient had no history of neoplasm except a hysterectomy for uterine leiomyoma five years before. Six months after the first presentation, the tumor showed a gradual increase in size; an explora...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-008-9084-8
更新日期:2008-07-01 00:00:00
abstract::Our aim was to compare Taxol-based chemotherapy response of non-small cell lung cancer (NSCLC) with P-glycoprotein (Pgp) or lung resistance protein expression (LRP). Immunohistochemical analyses were performed on multiple nonconsecutive sections of the biopsy specimens to detect Pgp and LPR expressions in 40 patients ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-003-1029-7
更新日期:2003-01-01 00:00:00
abstract:ABSTARCT:New anti-fibrotic agents for idiopathic pulmonary fibrosis (IPF) were approved based on the results of forced vital capacity (FVC) trends, although concerns were raised about the reliability of FVC as the only endpoint parameter. We hypothesized that IPF-specific multi-dimensional scores (Composite Physiologic...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-016-9963-3
更新日期:2017-02-01 00:00:00
abstract::Cessation of smoking in the home is one of the most important nonpharmacologic actions to be recommended. There is a highly significant increase in wheezing, coughing, and respiratory infections in children with smoking mothers, and this increase is directly proportional to the number of cigarettes smoked. Cord blood ...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718144
更新日期:1990-01-01 00:00:00
abstract::The role of leukotrienes in hypoxic vasoconstriction remains controversial. Our previous study using the lipoxygenase inhibitor BW 755C in dogs failed to show a substantive role for leukotrienes in hypoxic vasoconstriction. To clarify further the role of leukotrienes, we designed 3 protocols. In the first protocol, we...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF02714947
更新日期:1989-01-01 00:00:00
abstract::Accessory cardiac bronchus is a poorly recognized, usually asymptomatic, congenital abnormality of the bronchial tree. Recognition of bronchial anomalies is important since they are associated with clinical complications including recurrent episodes of infection, hemoptysis, and in some cases malignancy. ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-014-9617-2
更新日期:2014-10-01 00:00:00
abstract::We report two patients with atopic cough due to Basidiomycetes antigen. One patient was a 27 year-old woman and the other was a 17 year-old boy. Both patients visited our hospital because of severe nonproductive cough. They did not have bronchial hyperresponsiveness to methacholine or heightened bronchomotor tone. Bro...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-004-2509-0
更新日期:2004-01-01 00:00:00
abstract::We studied the influence of age on glutathione (GSH) content in the distal lung and the lung tissue of mice. From 1 to 28 months of age, the quantity of GSH and glutathione disulfide (GSSG) in bronchoalveolar lavage (BAL) fluid and in the lung tissue were determined. The GSH content in BAL fluid, which reflects the an...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00164439
更新日期:1994-01-01 00:00:00
abstract::The pathophysiology of cough variant asthma is poorly understood. In particular, the mechanisms that cause different symptoms in typical asthma (in which wheeze predominates) compared with cough variant asthma (in which cough predominates) have not been determined. Traditional explanations include higher wheezing thre...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-011-9348-6
更新日期:2012-02-01 00:00:00
abstract::We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00245-0
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To explore the role of CARM1 in lung cancer (LC) and its relationship with TP53 and CTNNB1. METHODS:Lung cells H1299 and PC14 were randomly divided into six groups: ov-H1299, si-H1299, ov-PC14, si-PC14, Con-H1299, and Con-PC14. Transwell assay, plate clone formation assay, and flow cytometry were used to det...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00324-7
更新日期:2020-04-01 00:00:00