Tracheobronchopathia osteochondroplastica: a rare large airway disorder.

abstract：:This study demonstrates for the first time that endothelial cells freshly isolated from small pulmonary arteries of the rat, based on their electrophysiological profile, possess two distinct populations of cells. Immunohistochemical staining revealed the presence of both anti-Kv1.5 and anti-Kir2.1 immunoreactivity in ...

journal_title：Lung

authors： Hogg DS,McMurray G,Kozlowski RZ

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) is accompanied by enhanced interleukin 18 (IL-18) expression in skeletal muscle, which may precede muscle weight loss. Twenty patients with moderate to severe COPD [12 women, 66 +/-...

journal_title：Lung

authors： Petersen AM,Penkowa M,Iversen M,Frydelund-Larsen L,Andersen JL,Mortensen J,Lange P,Pedersen BK

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a deadly disease, and the molecular mechanism of PAH has not been clarified clearly. The objective of this study was to identify possible biomarkers and explore the potential mechanisms of Schistosoma-induced PAH. METHODS:GSE49114 RNA-Seq data developed from mouse wh...

journal_title：Lung

authors： Sun Y,Lin X,Li L

更新日期：2017-06-01 00:00:00

abstract：:Allergen exposure in atopic asthmatic patients is associated with recruitment and activation of eosinophils in the airways. Once activated, eosinophils release toxic products, including the eosinophil cationic protein (ECP), able to damage bronchial structures and to increase bronchial hyperresponsiveness. With this b...

journal_title：Lung

authors： Oddera S,Silvestri M,Penna R,Galeazzi G,Crimi E,Rossi GA

更新日期：1998-01-01 00:00:00

abstract：:Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...

journal_title：Lung

authors： Keeney SE,Oelberg DG

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:TB nanodiagnostics have witnessed considerable development. However, most of the published reports did not proceed beyond proof-of-concept. Our objectives are to evaluate the diagnostic accuracy of a novel nanogold assay in detecting patients with active pulmonary TB based on results of BACTEC MGIT (reference t...

journal_title：Lung

authors： El-Samadony H,Azzazy HME,Tageldin MA,Ashour ME,Deraz IM,Elmaghraby T

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:Restoring the barrier integrity of the alveolar epithelium after injury is pivotal. In the current study, we evaluated the effects of surfactant, surfactant protein A (SP-A), transforming growth factor β (TGF-β), and analogues of SP-A on alveolar epithelial repair. Additionally, we assessed the influence of mic...

journal_title：Lung

authors： Willems CH,Zimmermann LJ,Langen RM,van den Bosch MJ,Kloosterboer N,Kramer BW,van Iwaarden JF

更新日期：2012-12-01 00:00:00

abstract：:The influence of phospholipids on the ultrastructure and metabolism of reconstituted surfactants has not been well defined. The aim of this study was to determine if changes in the phospholipid composition of reconstituted surfactants altered their biophysical properties, ultrastructure, and conversion to light subtyp...

journal_title：Lung

authors： Dhand R,Young J,Krishnasamy S,Possmayer F,Gross NJ

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Exercising or doing physical activity in polluted air could expose a person to the adverse health effects of air pollution. This study aimed to compare the cardiovascular and hematologic indices following an incremental exercise test (shuttle run) under clean versus polluted air conditions. METHODS:Nineteen ma...

journal_title：Lung

authors： Kargarfard M,Shariat A,Shaw BS,Shaw I,Lam ET,Kheiri A,Eatemadyboroujeni A,Tamrin SB

更新日期：2015-04-01 00:00:00

abstract：:It has been reported that a low concentration of exogenously applied vasoactive intestinal peptide (VIP) suppresses the release of acetylcholine (ACh) from vagus nerve terminals in the ferret and feline trachea. There has been, however, no documentation of the prejunctional action of VIP in the human airway. We observ...

journal_title：Lung

authors： Aizawa H,Inoue H,Shigyo M,Takata S,Koto H,Matsumoto K,Hara N

更新日期：1994-01-01 00:00:00

abstract：:The aim of our study was to evaluate clinical diagnoses in symptomatic persons exposed to aerosols from humidifiers or air conditioners. In addition, we tried to identify the causative antigens. Results of clinical investigations, including inhalation challenge tests, demonstrated a typical hypersensitivity pneumoniti...

journal_title：Lung

authors： Baur X,Behr J,Dewair M,Ehret W,Fruhmann G,Vogelmeier C,Weiss W,Zinkernagel V

更新日期：1988-01-01 00:00:00

abstract：:We studied the effect of hydralazine (H) on pulmonary vascular mechanics in an isolated, in situ, canine lobe model of normal and increased pulmonary vascular resistance (Rp) produced by Gelfoam embolization (GE). Pulmonary pressure-flow (P-Q) curves from 24 lobes were obtained at baseline and after each intervention....

journal_title：Lung

authors： Lupi-Herrera E,Furuya ME,Sandoval J,Correa E,Leal ME,Quesada A,Palomar A,Barrios R

更新日期：1992-01-01 00:00:00

abstract：:Reaginic antibodies in hay fever patients belong to IgE. The immunoglobulin sensitizes basophilic granulocytes and mast cells from homologous species and mediates the release of chemical mediators which cause allergic symptoms. The sensitization is due to the binding of IgE to receptors on the target cells through the...

journal_title：Lung

authors： Ishizaka K,Ishizaka T

更新日期：1978-01-01 00:00:00

abstract：:Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensa...

journal_title：Lung

authors： Kullmann T,Barta I,Antus B,Horváth I

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:Idiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies to alveolar epithelial and endothelial cells may be involved in the p...

journal_title：Lung

authors： Fahim A,Chong MC,Crooks MG,Hart SP

更新日期：2012-08-01 00:00:00

abstract：:This study was designed to determine the effects of thromboxane A2 (TxA2) on the distribution of vascular resistance, lung weight, and microvascular permeability in isolated dog lungs perfused at a constant pressure with autologous blood. The stable TxA2 analogue (STA2; 30 micrograms, n = 5) caused an increase in pulm...

journal_title：Lung

authors： Shibamoto T,Wang HG,Yamaguchi Y,Hayashi T,Saeki Y,Tanaka S,Koyama S

更新日期：1995-01-01 00:00:00

abstract：:The effect of tetraethylammonium (TEA) and K+ on contractions to histamine and acetylcholine have been compared in the pig isolated trachea using organ bath and sucrose-gap techniques. Histamine elicited weak contractions, compared with acetylcholine; however, these contractions were markedly potentiated by pretreatme...

journal_title：Lung

authors： Mitchell HW

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:Driving pressure (DP) while on ECMO has been studied in acute respiratory distress syndrome (ARDS) but no studies exist in those on ECMO without ARDS. We aimed to study association of mortality with DP in all patients on ECMO and compare change in DP before and after initiation of ECMO. METHODS:Consecutiv...

journal_title：Lung

authors： Gupta E,Awsare B,Hirose H,Cavarocchi N,Baram M

更新日期：2020-10-01 00:00:00

abstract：:The pathophysiology of cough variant asthma is poorly understood. In particular, the mechanisms that cause different symptoms in typical asthma (in which wheeze predominates) compared with cough variant asthma (in which cough predominates) have not been determined. Traditional explanations include higher wheezing thre...

journal_title：Lung

authors： Lougheed MD,Turcotte SE,Fisher T

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:We evaluated the diagnostic value for pulmonary embolism (PE) of the True fast imaging with steady-state precession (TrueFISP) MRI, a method that allows the visualization of pulmonary vasculature without breath holding or intravenous contrast. METHODS:This is a prospective investigation including 93 patient...

journal_title：Lung

authors： Pasin L,Zanon M,Moreira J,Moreira AL,Watte G,Marchiori E,Hochhegger B

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease is a progressive lung disease characterized by abnormal cellular responses to cigarette smoke, resulting in tissue destruction and airflow limitation. Autophagy is a fundamental cellular process that eliminates long-lived proteins and damaged organelles through lysosom...

journal_title：Lung

authors： Li L,Zhang M,Zhang L,Cheng Y,Tu X,Lu Z

更新日期：2017-06-01 00:00:00

abstract：:Six European treatment centers contributed to a controlled trial to study nocturnal hypoxemia in COPD patients having daytime PaO2 of 60-70 mmHg. The trial is composed of two parts: first, patients inclusion, taking men aged under 70 years, excluding sleep apnea syndrome and all other concomitant pathologies leading t...

journal_title：Lung

authors： Levi-Valensi P,Aubry P,Rida Z

更新日期：1990-01-01 00:00:00

abstract：:Occupational exposure to oyster mushroom (Pleurotus ostreatus) has been associated with obstructive lung disease. Previously, we studied an extract of oyster mushroom (OME) and determined that it causes dose-dependent contractions of nonsensitized guinea pig trachea (GPT). We extend these studies to the investigation ...

journal_title：Lung

authors： Schachter EN,Zuskin E,Pucarin-Cvetkovic J,Chiarelli A,Goswami S

更新日期：2011-08-01 00:00:00

abstract：:The practice of sedation dosing strategy in mechanically ventilated patient has a profound effect on cognitive function. We conducted a comprehensive review of outcome of sedation on mental health function in critically ill patients on mechanical ventilation in the intensive care unit (ICU). We specifically evaluated ...

journal_title：Lung

authors： Porhomayon J,El-Solh AA,Adlparvar G,Jaoude P,Nader ND

更新日期：2016-02-01 00:00:00

abstract：: ...

journal_title：Lung

authors： Adams TN,Newton CA,Glazer CS

更新日期：2019-02-01 00:00:00

abstract：:To determine whether changes in breathing pattern alone affect respiratory heat loss (RHL) and the constrictor response to cold dry gas hyperpnea in asthmatic subjects, we performed the following 2 part study: first we measured RHL in 8 asthmatic and 8 normal subjects during controlled eucapnic hyperpnea while they br...

journal_title：Lung

authors： Ingenito EP,Pichurko BM,Lafleur J,Drazen JM,Ingram RH Jr,Solway J

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Recent studies have shown the importance of Th17 cells in the development of allergic airway diseases. We examined Dermatophagoides pteronyssinus-induced changes in peripheral blood Th17 cells to establish the importance of these cells in late-phase allergic inflammation in patients with allergic rhinitis (A...

journal_title：Lung

authors： Bajoriuniene I,Malakauskas K,Lavinskiene S,Jeroch J,Gasiuniene E,Vitkauskiene A,Sakalauskas R

更新日期：2012-10-01 00:00:00

abstract：:Simulation-based medical education has gained tremendous popularity over the past two decades. Driven by the patient safety movement, changes in the educational opportunities available to trainees and the rapidly evolving capabilities of computer technology, simulation-based medical education is now being used across ...

journal_title：Lung

authors： Lam G,Ayas NT,Griesdale DE,Peets AD

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated non-inferiority of rivaroxaban when compared to warfarin for the treatment of pulmonary embolism and deep venous thrombosis. Analysis of data from the EINSTEIN trials has demonstrated that patients who received rivaroxaban had a shorter length of stay (LOS) compared to those ...

journal_title：Lung

authors： Desai A,Desai A,Calixte R,Aparnath M,Hindenburg A,Salzman S,Mathew JP

更新日期：2016-08-01 00:00:00