Acid glycosaminoglycans in experimental pleural effusions.

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated non-inferiority of rivaroxaban when compared to warfarin for the treatment of pulmonary embolism and deep venous thrombosis. Analysis of data from the EINSTEIN trials has demonstrated that patients who received rivaroxaban had a shorter length of stay (LOS) compared to those ...

journal_title：Lung

authors： Desai A,Desai A,Calixte R,Aparnath M,Hindenburg A,Salzman S,Mathew JP

更新日期：2016-08-01 00:00:00

abstract：:A multiuser system for whole body plethysmographic measurements and interpretation which has been developed under clinical conditions is described. The following measurements can be carried out in a rapid way and in one session with the patient: specific airway resistance during spontaneous breathing, determination of...

journal_title：Lung

authors： Zaiss AW,Matthys H

更新日期：1990-01-01 00:00:00

abstract：:A 15-year-old male had a history of increasing dyspnea on exertion, cough, sputum production, fever, weakness, hemoptysis, and diarrhea. Chest radiography demonstrated bilateral alveolar consolidation. Bronchoalveolar lavage fluid analysis revealed extensive hemosiderin-laden alveolar macrophages. On the basis of iron...

journal_title：Lung

authors： Hoca NT,Dayioglu D,Ogretensoy M

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:In immunocompromised patients with pulmonary infiltrates, transbronchial lung biopsies (TBB) obtained by forceps has been shown to increase the diagnostic yield over simple bronchoalveolar lavage. Cryo-TBB is a novel modality for obtaining lung biopsies. We aimed to evaluate for the first time the efficacy a...

journal_title：Lung

authors： Fruchter O,Fridel L,Rosengarten D,Rahman NA,Kramer MR

更新日期：2013-12-01 00:00:00

abstract：:The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of t...

journal_title：Lung

authors： Lee YK,Oh YM,Lee JH,Kim EK,Lee JH,Kim N,Seo JB,Lee SD,KOLD Study Group.

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:We report two patients with atopic cough due to Basidiomycetes antigen. One patient was a 27 year-old woman and the other was a 17 year-old boy. Both patients visited our hospital because of severe nonproductive cough. They did not have bronchial hyperresponsiveness to methacholine or heightened bronchomotor tone. Bro...

journal_title：Lung

authors： Ogawa H,Fujimura M,Tofuku Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Pulmonary endarterectomy is the treatment of choice in chronic thromboembolic pulmonary hypertension (CTEPH). Modern pulmonary vasoactive medication (like endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, and prostacyclins) is used in patients with an inoperable disease and improved progn...

journal_title：Lung

authors： Scholzel BE,Post MC,Thijs Plokker HW,Snijder RJ

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Acute exacerbations (AE) in patients with COPD are associated with a decline in lung function, increased risk of hospitalization, and mortality. In this cross-sectional study we tested whether the level of objectively measured daily physical activity and exercise capacity are associated with the number of COPD ...

journal_title：Lung

authors： Schönmann M,Sievi NA,Clarenbach CF,Brack T,Brutsche M,Frey M,Irani S,Leuppi JD,Ruediger J,Senn O,Thurnheer R,Kohler M

更新日期：2015-02-01 00:00:00

abstract：:It is well known that exposure to hyperoxia results in lung inflammation and damage, which leads to the development of chronic lung disease. Previous studies have shown increased activities of antioxidant enzymes (AOE) in lung tissue from animals exposed to hyperoxia. We propose the hypothesis that the fetal type II p...

journal_title：Lung

authors： Bhandari V,Maulik N,Kresch M

更新日期：2000-01-01 00:00:00

abstract：:Lung elastance and resistance increase in the supine posture. To evaluate the effects of change in posture on regional lung mechanics at different lung volumes, lung elastance and resistance were measured at graded volume subdivisions and three esophageal levels at seated and supine body positions, using the esophagea...

journal_title：Lung

authors： Baydur A,Sassoon CS,Carlson M

更新日期：1996-01-01 00:00:00

abstract：:This study demonstrates for the first time that endothelial cells freshly isolated from small pulmonary arteries of the rat, based on their electrophysiological profile, possess two distinct populations of cells. Immunohistochemical staining revealed the presence of both anti-Kv1.5 and anti-Kir2.1 immunoreactivity in ...

journal_title：Lung

authors： Hogg DS,McMurray G,Kozlowski RZ

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:The change in vital capacity from the seated to supine position (∆VC-supine) is used to screen for diaphragm dysfunction (DD), but some individuals are unable to tolerate the supine position. Since expiratory muscle function is often preserved in patients with isolated DD and inspiratory strength is reduced, th...

journal_title：Lung

authors： Koo P,Oyieng'o DO,Gartman EJ,Sethi JM,Eaton CB,McCool FD

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:The relationship between asthma and obesity is well established, although the pathophysiological mechanisms linking both diseases remain unknown. Adiponectin is a hormone secreted by adipose cells, plays a role in the modulation of inflammation and may be the key linking these two types of inflammation. METHOD...

journal_title：Lung

authors： de Lima Azambuja R,da Costa Santos Azambuja LS,Costa C,Rufino R

更新日期：2015-10-01 00:00:00

abstract：:Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...

journal_title：Lung

authors： Larsson S

更新日期：1990-01-01 00:00:00

abstract：:Extrinsic allergic alveolitis (EAA) caused by inhaled organic environmental allergens can progress to a fibrotic end-stage lung disease. Neovascularization plays an important role in pathogenesis of pulmonary fibrosis. The aim of this study was to assess the effect of sera from EAA patients on the angiogenic capabilit...

journal_title：Lung

authors： Zielonka TM,Demkow U,Filewska M,Bialas B,Zycinska K,Radzikowska E,Wardyn AK,Skopinska-Rozewska E

更新日期：2010-10-01 00:00:00

abstract：:To explore further the possible etiologic role of mycobacteria in the development of sarcoidosis, we measured free, nonbound tuberculostearic acid (TSA, 10-methyloctadecanoic), a component of mycobacteria, in the sera of subjects with sarcoidosis or active untreated pulmonary tuberculosis and in healthy controls by us...

journal_title：Lung

authors： Almenoff PL,Brooks JB,Johnson A,Lesser M

更新日期：1996-01-01 00:00:00

abstract：:Difficult weaning is fortunately a rare occurrence in mechanically ventilated patients in ICU. When faced with this problem, a vast number of factors must be carefully considered simultaneously: physiological adjustment, technical problems (tubing, circuit resistances, . . .) [13]. The most promising approach to diffi...

journal_title：Lung

authors： Chevrolet JC

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (NO) levels have been reported to be lower in patients with cystic fibrosis (CF) than in controls; however the mechanism(s) responsible and the effect on pathogenesis are unclear. The objective of these studies was to determine if the low levels of gas phase NO (gNO) could be reproduced ...

journal_title：Lung

authors： Ostrowski LE,Stewart D,Hazucha M

更新日期：2012-10-01 00:00:00

abstract：:The angiogenesis system has been implicated in inflammatory and neoplastic processes; nevertheless, it has been little studied in relation to the pleural space. Our aim is to analyze pleural and plasma levels of the activators--vascular endothelial growth factor, basic fibroblastic growth factor, and inhibitors--endos...

journal_title：Lung

authors： Ruiz E,Alemán C,Alegre J,Monasterio J,Segura RM,Armadans L,Vázquez A,Soriano T,Fernández de Sevilla T

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:Idiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies to alveolar epithelial and endothelial cells may be involved in the p...

journal_title：Lung

authors： Fahim A,Chong MC,Crooks MG,Hart SP

更新日期：2012-08-01 00:00:00

abstract：:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...

journal_title：Lung

authors： Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcomes. This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five-year period. Further, we compared our results to the 'World Association of Sarcoi...

journal_title：Lung

authors： Markevitz N,Epstein Shochet G,Levi Y,Israeli-Shani L,Shitrit D

更新日期：2017-08-01 00:00:00

abstract：:Bradykinin (10(-8) - 10(-5) M) caused a concentration-dependent increase in cyclic GMP (cGMP) production in bovine tracheal smooth muscle in the absence of epithelium. The effect was calcium-dependent and was inhibited by pyrogallol (10 microM) and methylene blue (10 microM). The inhibition of pyrogallol was reversed ...

journal_title：Lung

authors： Sheng H,Ishii K,Förstermann U,Murad F

更新日期：1995-01-01 00:00:00

abstract：:A 41-year-old woman presented with chest pain and a cough. There was a solitary pulmonary nodule in the upper-left lobe. The patient had no history of neoplasm except a hysterectomy for uterine leiomyoma five years before. Six months after the first presentation, the tumor showed a gradual increase in size; an explora...

journal_title：Lung

authors： Sapmaz F,Ergin M,Katrancioglu O,Gonlugur T,Gonlugur U,Elagoz S

更新日期：2008-07-01 00:00:00

abstract：:It has been reported that a low concentration of exogenously applied vasoactive intestinal peptide (VIP) suppresses the release of acetylcholine (ACh) from vagus nerve terminals in the ferret and feline trachea. There has been, however, no documentation of the prejunctional action of VIP in the human airway. We observ...

journal_title：Lung

authors： Aizawa H,Inoue H,Shigyo M,Takata S,Koto H,Matsumoto K,Hara N

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Patients with various chronic respiratory diseases have a higher incidence of gastroesophageal reflux disease (GERD)-related symptoms, but the mechanisms of the relationship between GERD symptoms and chronic obstructive pulmonary disease (COPD) remain unclear. The aim of the present study was to explore the ...

journal_title：Lung

authors： Liang BM,Feng YL

更新日期：2012-06-01 00:00:00

abstract：:During acute asthma reversible increase in lung compliance and total lung capacity (TLC) have been observed. The magnitude of the increase in TLC, however, was found to be relatively small when TLC was measured radiographically. We wondered if structural distortion of the respiratory bellows develops during acute asth...

journal_title：Lung

authors： Park SS,Stein L,Zelefsky MN

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00