Cholinergic innervation of BALT (bronchus associated lymphoid tissue) in rat.

abstract：BACKGROUND:There is very little evidence of the utility of the exhaled fraction of NO (FeNO) for the diagnosis of interstitial lung disease and nearly all of it is related with connective tissue disease. Some authors have suggested that in patients with hypersensitivity pneumonitis (HP), evolution to pulmonary fibrosis...

journal_title：Lung

authors： Ojanguren I,Cruz MJ,Villar A,Barrecheguren M,Morell F,Muñoz X

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...

journal_title：Lung

authors： Ramos-Casals M,Kostov B,Brito-Zerón P,Sisó-Almirall A,Baughman RP,Autoimmune Big Data Study Group.

更新日期：2019-08-01 00:00:00

abstract：:Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...

journal_title：Lung

authors： Bohadana AB,Michaely JP

更新日期：2006-05-01 00:00:00

abstract：:This study was designed to use volumetric capnography to evaluate the breathing pattern and ventilation inhomogeneities in patients with chronic sputum production and bronchiectasis and to correlate the phase 3 slope of the capnographic curve to spirometric measurements. Twenty-four patients with cystic fibrosis (CF) ...

journal_title：Lung

authors： Veronez L,Moreira MM,Soares ST,Pereira MC,Ribeiro MA,Ribeiro JD,Terzi RG,Martins LC,Paschoal IA

更新日期：2010-06-01 00:00:00

abstract：:Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...

journal_title：Lung

authors： Vantaggiato L,Perruzza M,Refini RM,Bergantini L,d'Alessandro M,Cameli P,Perruzza D,Bini L,Bargagli E,Landi C

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:The goal of our systematic review and meta-analysis is to examine the therapeutic effectiveness of bronchoscopic lung volume reduction (BLVR), and to compare it with medical management and lung volume reduction surgery. METHODS:Variables of interest were absolute change in FEV1, 6MWT, and SGRQ. Meta-analy...

journal_title：Lung

authors： Kumar A,Dy R,Singh K,Jeffery Mador M

更新日期：2017-02-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：:The aim of our study was to evaluate clinical diagnoses in symptomatic persons exposed to aerosols from humidifiers or air conditioners. In addition, we tried to identify the causative antigens. Results of clinical investigations, including inhalation challenge tests, demonstrated a typical hypersensitivity pneumoniti...

journal_title：Lung

authors： Baur X,Behr J,Dewair M,Ehret W,Fruhmann G,Vogelmeier C,Weiss W,Zinkernagel V

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...

journal_title：Lung

authors： Anderson WJ,Lipworth BJ

更新日期：2012-10-01 00:00:00

abstract：:Tuberculosis (TB) pleurisy is accepted to be the best model for evaluating the local protective cellular immune response to Mycobacterium tuberculosis (MTB) since it can be spontaneously self-cured. Therefore, we aimed to evaluate the involvement of cytokines and the soluble apoptosis-modulating factors sFas and sFasL...

journal_title：Lung

authors： Budak F,Uzaslan EK,Cangür S,Göral G,Oral HB

更新日期：2008-09-01 00:00:00

abstract：:Eosinophilic bronchitis is an essential component of bronchial asthma, and eosinophils play an important role. We studied the effect of eosinophils on cell surface plasmin generation by bronchial epithelial cells, because plasmin is thought to be involved in bronchial tissue repair/remodeling by means of fibrinolysis ...

journal_title：Lung

authors： Hara K,Hasegawa T,Ooi H,Koya T,Tanabe Y,Tsukada H,Igarashi K,Suzuki E,Arakawa M,Gejyo F

更新日期：2001-01-01 00:00:00

abstract：:In previous studies, we showed that Fischer rats fed 175 mg/kg of amiodarone accumulated large amounts of drug and metabolite in the lung and developed pulmonary toxicity, whereas Wistar rats fed the same drug dose had significantly less amiodarone in the lung and did not develop pulmonary inflammation. The present st...

journal_title：Lung

authors： Wilson BD,Lippmann ML

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Sildenafil was the only phosphodiesterase-5 inhibitor available for the treatment of pulmonary arterial hypertension (PAH) until the approval and availability of once-daily tadalafil. Since no direct comparative study is likely to be performed between these agents, we sought to evaluate the feasibility of tr...

journal_title：Lung

authors： Shlobin OA,Brown AW,Weir N,Ahmad S,Lemma M,Nathan SD

更新日期：2012-10-01 00:00:00

abstract：:Recently, active remodeling may indicate a good prognosis in idiopathic interstitial pneumonias. In this study we sought to validate the importance of the collagen/elastic system in the extracellular matrix remodeling and to study the relationships between the collagen/elastic system in nonspecific interstitial idiopa...

journal_title：Lung

authors： Felício CH,Parra ER,Capelozzi VL

更新日期：2007-01-01 00:00:00

abstract：:Isoniazid (INH) is one of the most important first line drugs in the treatment of tuberculosis. We utilized high performance liquid chromatography with a hydrazone extraction technique to measure INH in bronchoalveolar lavage (BAL) fluid specimens from six patients with active pulmonary tuberculosis. We found BAL flui...

journal_title：Lung

authors： O'Brien JK,Doerfler ME,Harkin TJ,Rom WN

更新日期：1998-01-01 00:00:00

abstract：:Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...

journal_title：Lung

authors： Muyal JP,Muyal V,Kotnala S,Kumar D,Bhardwaj H

更新日期：2013-04-01 00:00:00

abstract：:Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage. Breath condensa...

journal_title：Lung

authors： Kullmann T,Barta I,Antus B,Horváth I

更新日期：2008-07-01 00:00:00

abstract：:During acute asthma reversible increase in lung compliance and total lung capacity (TLC) have been observed. The magnitude of the increase in TLC, however, was found to be relatively small when TLC was measured radiographically. We wondered if structural distortion of the respiratory bellows develops during acute asth...

journal_title：Lung

authors： Park SS,Stein L,Zelefsky MN

更新日期：1993-01-01 00:00:00

abstract：:Air concentration of isocyanates are associated with the frequency of induced diseases. Asthma, bronchitis and rhinitis, chronic obstructive lung disease, and allergic alveolitis, respectively, were observed in exposed workers. Inhalation challenge tests with isocyanates found some 14% of symptomatic persons immunolog...

journal_title：Lung

authors： Baur X

更新日期：1990-01-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：:Cryoextraction is a procedure for recanalization of obstructed airways caused by exophytic growing tumors. Biopsy samples obtained with this method can be used for histological diagnosis. The objective of this study was to evaluate the parameters influencing the size of cryobiopsies in an in vitro animal model. New fl...

journal_title：Lung

authors： Franke KJ,Szyrach M,Nilius G,Hetzel J,Hetzel M,Ruehle KH,Enderle MD

更新日期：2009-08-01 00:00:00

abstract：:The contribution of T-cells after lung transplant (LTx) remains controversial with no current consensus of their role concerning chronic lung allograft dysfunction. Using flow cytometry to assess T-cell subsets of bronchoalveolar lavage fluid (BALF) in 16 cystic fibrosis (CF) LTx recipients, we identified a decline in...

journal_title：Lung

authors： Hayes D Jr,Harhay MO,Nicol KK,Liyanage NPM,Keller BC,Robinson RT

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Exercising or doing physical activity in polluted air could expose a person to the adverse health effects of air pollution. This study aimed to compare the cardiovascular and hematologic indices following an incremental exercise test (shuttle run) under clean versus polluted air conditions. METHODS:Nineteen ma...

journal_title：Lung

authors： Kargarfard M,Shariat A,Shaw BS,Shaw I,Lam ET,Kheiri A,Eatemadyboroujeni A,Tamrin SB

更新日期：2015-04-01 00:00:00

abstract：:Six European treatment centers contributed to a controlled trial to study nocturnal hypoxemia in COPD patients having daytime PaO2 of 60-70 mmHg. The trial is composed of two parts: first, patients inclusion, taking men aged under 70 years, excluding sleep apnea syndrome and all other concomitant pathologies leading t...

journal_title：Lung

authors： Levi-Valensi P,Aubry P,Rida Z

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00

abstract：:Impaired phagocytosis of Pseudomonas aeruginosa was found in isolated monocytes of peripheral blood of cystic fibrosis patients, but not in their neutrophils, as reported some years ago. In the present study, we analysed the phagocytic capacity of peripheral blood neutrophils and monocytes of cystic fibrosis patients ...

journal_title：Lung

authors： Leuer L,Krill A,Wilkens H,Wagenpfeil G,Bischoff M,Meier C,Bals R,Tschernig T

更新日期：2020-02-01 00:00:00

abstract：:Occupational exposure to oyster mushroom (Pleurotus ostreatus) has been associated with obstructive lung disease. Previously, we studied an extract of oyster mushroom (OME) and determined that it causes dose-dependent contractions of nonsensitized guinea pig trachea (GPT). We extend these studies to the investigation ...

journal_title：Lung

authors： Schachter EN,Zuskin E,Pucarin-Cvetkovic J,Chiarelli A,Goswami S

更新日期：2011-08-01 00:00:00

abstract：:The angiogenesis system has been implicated in inflammatory and neoplastic processes; nevertheless, it has been little studied in relation to the pleural space. Our aim is to analyze pleural and plasma levels of the activators--vascular endothelial growth factor, basic fibroblastic growth factor, and inhibitors--endos...

journal_title：Lung

authors： Ruiz E,Alemán C,Alegre J,Monasterio J,Segura RM,Armadans L,Vázquez A,Soriano T,Fernández de Sevilla T

更新日期：2005-05-01 00:00:00

abstract：:Immune cell airway infiltration and the bronchovascular remodeling process have shown to be promising in the understanding of bronchiolitis obliterans (BO) pathogenesis. In this study we sought to validate the importance of immune cells, whether diffusely distributed or forming lymphoid follicles, collagen density, an...

journal_title：Lung

authors： Garippo AL,Parra ER,Teodoro WR,Veloza AP,Yoshinari NH,Capelozzi VL

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Microbiological cultures are the mainstay of the diagnosis of tuberculosis (TB). False-positive TB results lead to significant unnecessary therapeutic and economic burden and are frequently caused by laboratory cross-contamination. The aim of this meta-analysis was to quantify the prevalence of laboratory cr...

journal_title：Lung

authors： Barac A,Karimzadeh-Esfahani H,Pourostadi M,Rahimi MT,Ahmadpour E,Rashedi J,Mahdavipoor B,Kafil HS,Spotin A,Abate KH,Mathioudakis AG,Asgharzadeh M

更新日期：2019-10-01 00:00:00