A Paradox: α-Klotho Levels and Smoking Intensity.

abstract：:The author reviews the early history of alpha 1-antitrypsin (AAT) deficiency; the biochemical characterization of this inborn error of metabolism, its pattern of inheritance, frequency and predisposition to early, panacinar emphysema. The importance of the destructive element in emphysema and the gradual focusing on n...

journal_title：Lung

authors： Eriksson S

更新日期：1990-01-01 00:00:00

abstract：:In severe asthma attacks beta 2-sympathomimetics lose part of their therapeutic efficiency. To elucidate this loss of efficiency in an experimental model we compared the relaxant potency of salbutamol (SAL), fenoterol (FEN), formoterol (FOR), and (-)-isoprenaline (ISO) in guinea pig tracheae partially and maximally pr...

journal_title：Lung

authors： Lemoine H,Overlack C,Köhl A,Worth H,Reinhardt D

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:The change in vital capacity from the seated to supine position (∆VC-supine) is used to screen for diaphragm dysfunction (DD), but some individuals are unable to tolerate the supine position. Since expiratory muscle function is often preserved in patients with isolated DD and inspiratory strength is reduced, th...

journal_title：Lung

authors： Koo P,Oyieng'o DO,Gartman EJ,Sethi JM,Eaton CB,McCool FD

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Lymphangioleiomyomatosis (LAM) is a rare, progressive, frequently lethal cystic lung disease that almost exclusively affects women. Prognostic information in LAM has been limited by small numbers and heterogeneous study methodology. Early retrospective cohorts cited 5- and 10-year mortality of 40 and 80 %, resp...

journal_title：Lung

authors： Oprescu N,McCormack FX,Byrnes S,Kinder BW

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:Acute exacerbations (AE) in patients with COPD are associated with a decline in lung function, increased risk of hospitalization, and mortality. In this cross-sectional study we tested whether the level of objectively measured daily physical activity and exercise capacity are associated with the number of COPD ...

journal_title：Lung

authors： Schönmann M,Sievi NA,Clarenbach CF,Brack T,Brutsche M,Frey M,Irani S,Leuppi JD,Ruediger J,Senn O,Thurnheer R,Kohler M

更新日期：2015-02-01 00:00:00

abstract：:While the care of cystic fibrosis (CF) patients has been mainly the province of pediatricians, great improvements in the therapy and life span of CF patients often results in their transition to care by adult physicians. In this review of CF, we begin with an overview of the epidemiology and genetics of the disease, w...

journal_title：Lung

authors： Bye MR,Ewig JM,Quittell LM

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated non-inferiority of rivaroxaban when compared to warfarin for the treatment of pulmonary embolism and deep venous thrombosis. Analysis of data from the EINSTEIN trials has demonstrated that patients who received rivaroxaban had a shorter length of stay (LOS) compared to those ...

journal_title：Lung

authors： Desai A,Desai A,Calixte R,Aparnath M,Hindenburg A,Salzman S,Mathew JP

更新日期：2016-08-01 00:00:00

abstract：:The effects of vitamin E deficiency on bleomycin (BLM)-induced pulmonary fibrosis have been studied by analyses of pressure volume (PV) curves and morphological examinations. Golden hamsters were divided into groups on a control diet (group C), vitamin E-deficient diet (E), control diet with BLM treatment (CB), and vi...

journal_title：Lung

authors： Nakamura H,Sato S,Takahashi K

更新日期：1988-01-01 00:00:00

abstract：:To explore further the possible etiologic role of mycobacteria in the development of sarcoidosis, we measured free, nonbound tuberculostearic acid (TSA, 10-methyloctadecanoic), a component of mycobacteria, in the sera of subjects with sarcoidosis or active untreated pulmonary tuberculosis and in healthy controls by us...

journal_title：Lung

authors： Almenoff PL,Brooks JB,Johnson A,Lesser M

更新日期：1996-01-01 00:00:00

abstract：INTRODUCTION:Prophylactic continuous positive airway pressure (CPAP) can prevent pulmonary adverse events following upper abdominal surgeries. The present meta-regression evaluates and quantifies the effect of degree/duration of (CPAP) on the incidence of postoperative pulmonary events. METHODS:Medical databases were ...

journal_title：Lung

authors： Singh PM,Borle A,Shah D,Sinha A,Makkar JK,Trikha A,Goudra BG

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:We evaluated the diagnostic value for pulmonary embolism (PE) of the True fast imaging with steady-state precession (TrueFISP) MRI, a method that allows the visualization of pulmonary vasculature without breath holding or intravenous contrast. METHODS:This is a prospective investigation including 93 patient...

journal_title：Lung

authors： Pasin L,Zanon M,Moreira J,Moreira AL,Watte G,Marchiori E,Hochhegger B

更新日期：2017-04-01 00:00:00

abstract：:The normal balance between coagulation and fibrinolysis in the pleural cavity is poorly understood despite the critical role of the pleura in the movement of the lungs. To determine the fibrinolytic activity and the interaction between plasminogen activators and their inhibitors in the normal pleural space, we tested ...

journal_title：Lung

authors： Li XY,Brown GM,Lamb D,Donaldson K

更新日期：1990-01-01 00:00:00

abstract：:Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...

journal_title：Lung

authors： Larsson S

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:The cardinal symptom of pulmonary hypertension (PH) is dyspnea on exertion, leading to decreased activity in daily living. The aim of this study was to analyze daily physical activity in incident patients with arterial or chronic thromboembolic PH (PAH/CTEPH) and to investigate its correlation with pulmona...

journal_title：Lung

authors： Saxer S,Lichtblau M,Berlier C,Hasler ED,Schwarz EI,Ulrich S

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:We investigated outcomes of patients hospitalized with community-acquired pneumonia (CAP) according to the changes in red cell distribution width (RDW). METHODS:For 980 adults, clinical characteristics, outcomes during hospitalization for CAP (transfer to the intensive care unit, treatment with mechanical vent...

journal_title：Lung

authors： Gorelik O,Izhakian S,Barchel D,Almoznino-Sarafian D,Tzur I,Swarka M,Beberashvili I,Feldman L,Cohen N,Shteinshnaider M

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Flexible fiberoptic bronchoscopy (FFB) plays an important role in the surveillance of cystic fibrosis (CF) patients after lung transplantation (LTx). With rapid onset and clearance, propofol provides a safe and efficient method for sedation during FFB, yet sedation requirements for CF patients are not well...

journal_title：Lung

authors： Ho C,Hayes D Jr,Khosravi M,Splaingard ML,Tumin D,Lloyd EA

更新日期：2018-08-01 00:00:00

abstract：:Diffuse alveolar damage is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). A significant proportion of ARDS survivors have residual pulmonary fibrosis and compromised pulmonary function. On the other hand, heat shock protein 47 (HSP47) is a collagen-binding stress protein that is assumed to...

journal_title：Lung

authors： Hagiwara S,Iwasaka H,Matsumoto S,Noguchi T,Yoshioka H

更新日期：2007-01-01 00:00:00

abstract：:Albumin diffusion measured in an isolated segment of rabbit lung interstitium with a radioactive tracer ((125)I-albumin) technique was independent of albumin concentration and similar to the free diffusion of albumin in water (Qiu et al, 1998. J Appl Physiol 85: 575-583). We studied the effect of hyaluronidase on the ...

journal_title：Lung

authors： Qiu XL,Brown LV,Parameswaran S,Marek VW,Ibbott GS,Lai-Fook SJ

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:This is a meta-analysis of the safety and efficacy of indacaterol in chronic obstructive pulmonary disease (COPD) with treatment duration of ≥12 weeks. METHODS:Randomized controlled trials (RCTs) reported in English (to September 30, 2012) were identified from PubMed, the Cochrane Library, Embase, websites,...

journal_title：Lung

authors： Jiang FM,Liang ZA,Zheng QL,Wang RC,Luo J,Li CT

更新日期：2013-04-01 00:00:00

abstract：:Pulmonary histiocytosis X is characterized by an accumulation of CD-1-positive histiocytosis X cells in the lung, which also can be found in the bronchoalveolar lavage fluid (BALF). However, it has recently been demonstrated that CD-1-positive cells can also be detected in BALF of patients with other interstitial lung...

journal_title：Lung

authors： Auerswald U,Barth J,Magnussen H

更新日期：1991-01-01 00:00:00

abstract：:The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...

journal_title：Lung

authors： Nadal D,Ogra PL

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. It is not known which clinical markers are predictive of PH in COPD. The goal of this study was to develop a clinical tool to identify patients who should be sent for ini...

journal_title：Lung

authors： Gartman EJ,Blundin M,Klinger JR,Yammine J,Roberts MB,Dennis McCool F

更新日期：2012-02-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：:A nodular lesion in the medial segment of right middle lobe was discovered on a chest radiograph for chronic cough in a 42-year-old Asian woman. A chest computed tomography (CT) scan subsequently showed a right middle lobe (RML) nodular lesion, which exhibited intense fluorodeoxyglucose uptake on positron emission tom...

journal_title：Lung

authors： Fang HY,Wu CY,Huang HJ,Lin YM

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal fibrosing lung disease with a median survival of approximately 3 years after diagnosis. The only medical option to improve survival in IPF is lung transplantation (LTX). The purpose of this study was to evaluate trajectory data of IPF patients...

journal_title：Lung

authors： ten Klooster L,Nossent GD,Kwakkel-van Erp JM,van Kessel DA,Oudijk EJ,van de Graaf EA,Luijk B,Hoek RA,van den Blink B,van Hal PT,Verschuuren EA,van der Bij W,van Moorsel CH,Grutters JC

更新日期：2015-12-01 00:00:00

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and ran...

journal_title：Lung

authors： Abu-Hijleh M,Lee D,Braman SS

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:In immunocompromised patients with pulmonary infiltrates, transbronchial lung biopsies (TBB) obtained by forceps has been shown to increase the diagnostic yield over simple bronchoalveolar lavage. Cryo-TBB is a novel modality for obtaining lung biopsies. We aimed to evaluate for the first time the efficacy a...

journal_title：Lung

authors： Fruchter O,Fridel L,Rosengarten D,Rahman NA,Kramer MR

更新日期：2013-12-01 00:00:00

abstract：:In recent years the alveolar macrophage has been found to play a central role in interstitial lung disease. Pulmonary histiocytosis X is characterized by infiltrating fibroblasts, mononuclear cells, and CD-1-positive Langerhans cells. Bronchoalveolar lavage (BAL) fluid displays an increase of CD-1-positive cells and a...

journal_title：Lung

authors： Uebelhoer M,Bewig B,Sternberg K,Rabe K,Nowak D,Magnussen H,Barth J

更新日期：1995-01-01 00:00:00

abstract：PURPOSE:Improving dyspnea and exercise performance are goals of COPD therapy. We tested the hypothesis that air current applied to the face would lessen dyspnea and improve exercise performance in moderate-severe COPD patients. METHODS:We recruited 10 COPD patients (5 men, age 62 ± 6 years, FEV1 0.93 ± 0.11 L (34 ± 3%...

journal_title：Lung

authors： Marchetti N,Lammi MR,Travaline JM,Ciccolella D,Civic B,Criner GJ

更新日期：2015-10-01 00:00:00

abstract：:In previous studies, we showed that Fischer rats fed 175 mg/kg of amiodarone accumulated large amounts of drug and metabolite in the lung and developed pulmonary toxicity, whereas Wistar rats fed the same drug dose had significantly less amiodarone in the lung and did not develop pulmonary inflammation. The present st...

journal_title：Lung

authors： Wilson BD,Lippmann ML

更新日期：1996-01-01 00:00:00