Secretion of plasminogen activator inhibitor by normal rat pleural leukocytes in culture.

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that the exposure to hyperbaric hyperoxia increased respiratory system elastance and both the "ohmic" and viscoelastic components of inspiratory resistances, probably because of increased oxygen tension toxic effects. We presently investigated the possible consequences of a single ...

journal_title：Lung

authors： Rubini A,Porzionato A,Sarasin G,Zara S,Macchi V,Camporesi E,Bosco G

更新日期：2014-08-01 00:00:00

abstract：:Chronic desquamative eosinophilic bronchitis is a characteristic pathologic feature of asthma which may even antedate the onset of symptoms. The pharmacology of asthmatic inflammation has been relatively poorly studied and most of the current data available have been inferred indirectly from studies of bronchial hyper...

journal_title：Lung

authors： Chung KF

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Lymphangioleiomyomatosis (LAM) is a rare, progressive, frequently lethal cystic lung disease that almost exclusively affects women. Prognostic information in LAM has been limited by small numbers and heterogeneous study methodology. Early retrospective cohorts cited 5- and 10-year mortality of 40 and 80 %, resp...

journal_title：Lung

authors： Oprescu N,McCormack FX,Byrnes S,Kinder BW

更新日期：2013-02-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to determine if electrocardiographically synchronized, prospectively triggered multidetector row computed tomography (ECG-MDR-CT) angiography of the aorta can accurately predict the location of ectopic bronchial arteries in patients with cystic fibrosis (CF) with massive hemop...

journal_title：Lung

authors： Hayes D Jr,Winkler MA,Kirkby S,Capasso P,Mansour HM,Attili AK

更新日期：2012-04-01 00:00:00

abstract：:Group B streptococcal (GBS) pneumonia, with neutrophilic granulocytes immigrating into the lungs, may occur in neonates. The incidence is particularly high among preterm infants, who often are treated with exogenous surfactant. We have previously demonstrated in vitro that neutrophils stimulated by GBS cause lipid per...

journal_title：Lung

authors： Bouhafs RK,Jarstrand C,Robertson B

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:To evaluate the cardio-pulmonary hemodynamics changes before and after valve treatment, and their correlation with lobe volume reduction. METHODS:This retrospective multicentre study included consecutive patients undergoing bronchoscopic valve treatment for heterogeneous emphysema. In addition to standard...

journal_title：Lung

authors： Fiorelli A,Cascone R,Natale G,Peritore V,Vanni C,Poggi C,Venuta F,Rendina EA,Santini M,Andreetti C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Melanocortin 3 Receptor (MC3R) is one of the families of seven-transmembrane G-protein-coupled receptors, and a recent study showed that MCR3 promoter polymorphism was significantly associated with the susceptibility of tuberculosis (TB) in South African population. METHODS:We analyzed six MC3R polymorphisms t...

journal_title：Lung

authors： Park BL,Kim LH,Namgoong S,Kim JO,Kim JY,Chang HS,Park JS,Jang AS,Park SW,Kim DJ,Kim KU,Kim YG,Uh ST,Seo KH,Kim YH,Park CS,Shin HD

更新日期：2014-12-01 00:00:00

abstract：:The presence and distribution of acetylcholinesterase (AChE) and cholineacetyl transferase activities (Chat) were examined in the bronchus-associated lymphoid tissue (BALT) of juvenile, adult and old rats. Histoenzymatic and immunochemical methods were used in association with quantitative analysis of images and stati...

journal_title：Lung

authors： Cavallotti C,Tonnarini GF,Tranquilli Leali FM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Pulmonary endarterectomy is the treatment of choice in chronic thromboembolic pulmonary hypertension (CTEPH). Modern pulmonary vasoactive medication (like endothelin receptor antagonists, phosphodiesterase type 5 inhibitors, and prostacyclins) is used in patients with an inoperable disease and improved progn...

journal_title：Lung

authors： Scholzel BE,Post MC,Thijs Plokker HW,Snijder RJ

更新日期：2012-04-01 00:00:00

abstract：:Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...

journal_title：Lung

authors： Bohadana AB,Michaely JP

更新日期：2006-05-01 00:00:00

abstract：:Adolescent idiopathic scoliosis may require surgical treatment for extreme curvature of the spine or loss of pulmonary function. We present a report of a 31-year-old woman with a history of scoliosis and anterolateral spinal fusion who developed chest pain and hemoptysis. Imaging revealed that a fixation rod had migra...

journal_title：Lung

authors： Song KJ,Colman M,Myers JA,Seder CW

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Patients with various chronic respiratory diseases have a higher incidence of gastroesophageal reflux disease (GERD)-related symptoms, but the mechanisms of the relationship between GERD symptoms and chronic obstructive pulmonary disease (COPD) remain unclear. The aim of the present study was to explore the ...

journal_title：Lung

authors： Liang BM,Feng YL

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Improving dyspnea and exercise performance are goals of COPD therapy. We tested the hypothesis that air current applied to the face would lessen dyspnea and improve exercise performance in moderate-severe COPD patients. METHODS:We recruited 10 COPD patients (5 men, age 62 ± 6 years, FEV1 0.93 ± 0.11 L (34 ± 3%...

journal_title：Lung

authors： Marchetti N,Lammi MR,Travaline JM,Ciccolella D,Civic B,Criner GJ

更新日期：2015-10-01 00:00:00

abstract：:We studied the effect of hydralazine (H) on pulmonary vascular mechanics in an isolated, in situ, canine lobe model of normal and increased pulmonary vascular resistance (Rp) produced by Gelfoam embolization (GE). Pulmonary pressure-flow (P-Q) curves from 24 lobes were obtained at baseline and after each intervention....

journal_title：Lung

authors： Lupi-Herrera E,Furuya ME,Sandoval J,Correa E,Leal ME,Quesada A,Palomar A,Barrios R

更新日期：1992-01-01 00:00:00

abstract：:Particulate matter less than PM(10) and aromatic chemicals formed during incomplete combustion of organic matter are major environmental pollutants because of their toxic potential. The present study reports on the respiratory morbidity pattern of people exposed to auto exhaust as a result of the traffic load consisti...

journal_title：Lung

authors： Chattopadhyay BP,Mukherjee A,Mukherjee K,Roychowdhury A

更新日期：2007-09-01 00:00:00

abstract：:The major goal of all diagnostic and therapeutic efforts in childhood asthma is to prevent progression of lung disease into adulthood. To improve the uncomfortable situation of underdiagnosis and undertreatment and to lower the risk of acquiring irreversible lung damage, an optimal co-working relationship between fami...

journal_title：Lung

authors： Kraemer R,Speck S,Schöni MH

更新日期：1990-01-01 00:00:00

abstract：:Acid glycosaminoglycans (GAG) were quantitated and partially characterized in pleural effusions in guinea pigs with experimental allergic pleurisy. Increase of GAG in the pleural effusion preceded the increase of effusion volume. Effusion was associated with the presence of cuboidal mesothelial cells on visceral pleur...

journal_title：Lung

authors： Satoh K,Arai H,Nagai H,Ito M,Sato H,Motomiya M,Konno K

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:According to the National Family Health Survey, asthma is one of the leading diseases in India. In order to understand the complexity of asthma, the susceptibility genes need to be targeted for their association. Glutathione S-transferases play a major role in the detoxification of metabolites of oxidative s...

journal_title：Lung

authors： Birbian N,Singh J,Jindal SK,Joshi A,Batra N,Singla N

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:In immunocompromised patients with pulmonary infiltrates, transbronchial lung biopsies (TBB) obtained by forceps has been shown to increase the diagnostic yield over simple bronchoalveolar lavage. Cryo-TBB is a novel modality for obtaining lung biopsies. We aimed to evaluate for the first time the efficacy a...

journal_title：Lung

authors： Fruchter O,Fridel L,Rosengarten D,Rahman NA,Kramer MR

更新日期：2013-12-01 00:00:00

abstract：:Diffuse alveolar damage is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). A significant proportion of ARDS survivors have residual pulmonary fibrosis and compromised pulmonary function. On the other hand, heat shock protein 47 (HSP47) is a collagen-binding stress protein that is assumed to...

journal_title：Lung

authors： Hagiwara S,Iwasaka H,Matsumoto S,Noguchi T,Yoshioka H

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The right ventricular ejection fraction (RVEF) is a surrogate marker of right ventricular function in pulmonary hypertension (PH), but its measurement is complicated and time consuming. The tricuspid annular plane systolic excursion (TAPSE) measures only the longitudinal component of RV contraction while the...

journal_title：Lung

authors： Hoette S,Creuzé N,Günther S,Montani D,Savale L,Jaïs X,Parent F,Sitbon O,Rochitte CE,Simonneau G,Humbert M,Souza R,Chemla D

更新日期：2018-04-01 00:00:00

abstract：:Cardiothoracic surgery posits an arrangement of large, significant hemodynamic, and physiologic alterations upon the human body, which predisposes a patient to develop pathology. The care of these patients in the postoperative realm requires an astute physician with deep understanding of the cardiopulmonary system, wh...

journal_title：Lung

authors： Tanner TG,Colvin MO

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Malignant mesothelioma is an aggressive tumor of serosal surfaces that is closely associated with asbestos exposure which induces oxidative stress. Heme oxygenase (HO)-1, a rate-limiting enzyme of heme degradation, plays a protective role against oxidative stress. The HO-1 gene promoter carries (GT)n repeats...

journal_title：Lung

authors： Murakami A,Fujimori Y,Yoshikawa Y,Yamada S,Tamura K,Hirayama N,Terada T,Kuribayashi K,Tabata C,Fukuoka K,Tamaoki T,Nakano T

更新日期：2012-06-01 00:00:00

abstract：:Bronchial provocation studies performed in our research center have consistently demonstrated airway hyperresponsiveness to both inhaled methacholine and histamine in subjects with chronic cervical spinal cord injury (SCI). More recently, we reported that the airways of such subjects maintained on chronic baclofen (ga...

journal_title：Lung

authors： Grimm DR,DeLuca RV,Lesser M,Bauman WA,Almenoff PL

更新日期：1997-01-01 00:00:00

abstract：:The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...

journal_title：Lung

authors： Lai-Fook SJ

更新日期：1987-01-01 00:00:00

abstract：:The effect of azelastine and some selected compounds on ciliary beating frequency (CBF) was investigated in vitro using human mucosal samples and in vivo using anesthetized guinea pigs. Further influence of azelastine on mucus secretion was evaluated in mice and on mucociliary clearance in anesthetized rabbits. Azelas...

journal_title：Lung

authors： Achterrath-Tuckermann U,Saano V,Minker E,Stroman F,Arny I,Joki S,Nuutinen J,Szelenyi I

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Histological subdivision into typical (TC) and atypical (AC) is crucial for treatment and prognosis of lung carcinoids but can be also very challenging, even for experts. In this study, we aimed to strengthen or reduce the prognostic value of several pathological, clinical, or per-operative factors some of w...

journal_title：Lung

authors： Cusumano G,Fournel L,Strano S,Damotte D,Charpentier MC,Galia A,Terminella A,Nicolosi M,Regnard JF,Alifano M

更新日期：2017-12-01 00:00:00

abstract：:Respiratory adaptation during sleep improves with growth. The most vulnerable period for respiratory adaptation to sleep is from birth to 3 months of age. Factors that favor vulnerability are immaturity in ventilatory control and high rib cage compliance which impairs its effectiveness for ventilation. Improvement in ...

journal_title：Lung

authors： Gaultier C

更新日期：1990-01-01 00:00:00

abstract：:Genomic alterations in lung cancer tissues have been observed in various studies. To analyze the aberrations in the genome of lung cancer patients, we used array comparative genomic hybridization (array CGH) in 15 lung adenocarcinoma (AdC) tissues. Copy number gains and losses in chromosomal regions were detected and ...

journal_title：Lung

authors： Choi JS,Zheng LT,Ha E,Lim YJ,Kim YH,Wang YP,Lim Y

更新日期：2006-11-01 00:00:00