Age-related changes in the antioxidant screen of the distal lung in mice.

abstract：:Alveolar epithelial type II (AT II) cells need phosphate (Pi) for surfactant synthesis. The Na-dependent (Na(d)) Pi transporters NaPi-IIb and Pit-1 are expressed in lung, but their expression, regulation, and function in AT II cells remain unclear. We studied NaPi-IIb and Pit-1 mRNA expression in cultured AT II cells ...

journal_title：Lung

authors： Jin C,Zoidis E,Ghirlanda C,Schmid C

更新日期：2010-01-01 00:00:00

abstract：:A 15-year-old male had a history of increasing dyspnea on exertion, cough, sputum production, fever, weakness, hemoptysis, and diarrhea. Chest radiography demonstrated bilateral alveolar consolidation. Bronchoalveolar lavage fluid analysis revealed extensive hemosiderin-laden alveolar macrophages. On the basis of iron...

journal_title：Lung

authors： Hoca NT,Dayioglu D,Ogretensoy M

更新日期：2006-09-01 00:00:00

abstract：:The lung has only a limited pattern of response to injury. Idiopathic interstitial fibrosis is a descriptive term, describing the end stage of one pattern of pulmonary fibrosis in which the inflammation lies within the structure of the alveolar walls and around vessels and bronchioli, in the interstitium. The disease ...

journal_title：Lung

authors： Lambe D

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide and is proved to be the number three cause of death in globally. The objective of this study was to explore the molecular mechanism of the progression of COPD. METHODS:Using the GSE1650 affymetrix microarray data acces...

journal_title：Lung

authors： Ye J,Wen L,Liu DL,Lai GX

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...

journal_title：Lung

authors： Myint ZW,McCormick J,Chauhan A,Behrens E,Anthony LB

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:We investigated outcomes of patients hospitalized with community-acquired pneumonia (CAP) according to the changes in red cell distribution width (RDW). METHODS:For 980 adults, clinical characteristics, outcomes during hospitalization for CAP (transfer to the intensive care unit, treatment with mechanical vent...

journal_title：Lung

authors： Gorelik O,Izhakian S,Barchel D,Almoznino-Sarafian D,Tzur I,Swarka M,Beberashvili I,Feldman L,Cohen N,Shteinshnaider M

更新日期：2016-12-01 00:00:00

abstract：:Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution. It plays important roles in various pathophysiological processes, including tissue remodeling, reproduction, lipid transport, complement regulation, and apoptosis. Clusterin appears to have two main isoforms that result from alternati...

journal_title：Lung

authors： Li H,Liu S,Zhu X,Yang S,Xiang J,Chen H

更新日期：2010-10-01 00:00:00

abstract：:The bronchus associated lymphoid tissue (BALT) and the precursor immunocompetent lymphoid cells in the nasopharynx, tonsils, and salivary glands represent the basic source of specific secretory IgA, other immunoglobulin, and T cell mediated specific immunity in the respiratory tract. The bulk of this immunologic react...

journal_title：Lung

authors： Nadal D,Ogra PL

更新日期：1990-01-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PCP) is the most common presenting symptom in patients with the acquired immunodeficiency syndrome (AIDS). Clinical trials have shown that inhaled pentamidine, delivered by nebulizer, is an effective prophylaxis for PCP in high-risk patients, and can be used to treat mild to moderate ep...

journal_title：Lung

authors： Newman SP,Simonds AK

更新日期：1990-01-01 00:00:00

abstract：:The major goal of all diagnostic and therapeutic efforts in childhood asthma is to prevent progression of lung disease into adulthood. To improve the uncomfortable situation of underdiagnosis and undertreatment and to lower the risk of acquiring irreversible lung damage, an optimal co-working relationship between fami...

journal_title：Lung

authors： Kraemer R,Speck S,Schöni MH

更新日期：1990-01-01 00:00:00

abstract：:A large-scale outbreak of life-threatening, inhaled synthetic cannabinoids (Spice/K2)-associated coagulopathy with bleeding complications was recently reported in Illinois. The causative agents were brodifacoum, difenacoum, and bromadiolone, potent, long-acting, 4-hydroxycoumarin anticoagulant rodenticides (LAAR) that...

journal_title：Lung

authors： Tole M,LaBedz S,Feinstein DL,Rubinstein I

更新日期：2019-06-01 00:00:00

abstract：:The efficacy of the docetaxel-carboplatin combination chemotherapy was studied in various phase II studies. Based on these data we aimed to test the regimen in previously untreated patients with advanced advanced non-smoking lung cancer (NSCLC) with docetaxel 80 mg/m2 a standard dose of carboplatin at AUC = 5, in an a...

journal_title：Lung

authors： Tsavaris N,Kosmas C,Skopelitis E,Gennatas K,Zorbala A,Papas P,Gouveris P,Antypas G,Rokana S,Tzelepis G

更新日期：2005-11-01 00:00:00

abstract：:The angiogenesis system has been implicated in inflammatory and neoplastic processes; nevertheless, it has been little studied in relation to the pleural space. Our aim is to analyze pleural and plasma levels of the activators--vascular endothelial growth factor, basic fibroblastic growth factor, and inhibitors--endos...

journal_title：Lung

authors： Ruiz E,Alemán C,Alegre J,Monasterio J,Segura RM,Armadans L,Vázquez A,Soriano T,Fernández de Sevilla T

更新日期：2005-05-01 00:00:00

abstract：:The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of t...

journal_title：Lung

authors： Lee YK,Oh YM,Lee JH,Kim EK,Lee JH,Kim N,Seo JB,Lee SD,KOLD Study Group.

更新日期：2008-05-01 00:00:00

abstract：:It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...

journal_title：Lung

authors： Pleguezuelos E,Guirao L,Moreno E,Samitier B,Ortega P,Vila X,Garnacho-Castaño MV,Majó M,Ovejero L,Miravitlles M

更新日期：2018-12-01 00:00:00

abstract：:There is a lack of evidence about whether menopausal status influences the effect of smoking on lung function. This study examined the association between smoking and menopausal status and lung function independent of each other. Data were from a cohort of women attending the 21-year follow-up of the Mater University ...

journal_title：Lung

authors： Hayatbakhsh MR,Najman JM,O'Callaghan MJ,Williams GM,Paydar A,Clavarino A

更新日期：2011-02-01 00:00:00

abstract：:To determine the role of the alveolar pores in cigarette smoke-induced lung disease, we examined the alveolar pores of guinea pigs exposed to cigarette smoke for 12 months, and compared these data to those obtained from sham-smoked animals, correlating the data with airspace size and lung function. We found that the s...

journal_title：Lung

authors： Wright JL

更新日期：2001-01-01 00:00:00

abstract：:Six European treatment centers contributed to a controlled trial to study nocturnal hypoxemia in COPD patients having daytime PaO2 of 60-70 mmHg. The trial is composed of two parts: first, patients inclusion, taking men aged under 70 years, excluding sleep apnea syndrome and all other concomitant pathologies leading t...

journal_title：Lung

authors： Levi-Valensi P,Aubry P,Rida Z

更新日期：1990-01-01 00:00:00

abstract：INTRODUCTION:Hypoxia has been implicated in the pathogenesis of many inflammatory and fibrotic lung diseases. The effect of hypoxia on epithelial junction protein expression is yet to be fully elucidated but evidence suggests a protective role for the hypoxia-inducible transcription factor HIF-1 in stabilising occludin...

journal_title：Lung

authors： Li L,Watson CJ,Dubourd M,Bruton A,Xu M,Cooke G,Baugh JA

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Bronchopleural fistula is a rare but potentially fatal complication of pulmonary resections and proper management is essential for its resolution. In this study, we analyzed the incidence of fistula after pulmonary resection and reported data about endoscopic and conservative treatments of this complicatio...

journal_title：Lung

authors： Fuso L,Varone F,Nachira D,Leli I,Salimbene I,Congedo MT,Margaritora S,Granone P

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Exhaled nitric oxide (NO) levels have been reported to be lower in patients with cystic fibrosis (CF) than in controls; however the mechanism(s) responsible and the effect on pathogenesis are unclear. The objective of these studies was to determine if the low levels of gas phase NO (gNO) could be reproduced ...

journal_title：Lung

authors： Ostrowski LE,Stewart D,Hazucha M

更新日期：2012-10-01 00:00:00

abstract：:Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...

journal_title：Lung

authors： Larsson S

更新日期：1990-01-01 00:00:00

abstract：:The aim of our study was to evaluate clinical diagnoses in symptomatic persons exposed to aerosols from humidifiers or air conditioners. In addition, we tried to identify the causative antigens. Results of clinical investigations, including inhalation challenge tests, demonstrated a typical hypersensitivity pneumoniti...

journal_title：Lung

authors： Baur X,Behr J,Dewair M,Ehret W,Fruhmann G,Vogelmeier C,Weiss W,Zinkernagel V

更新日期：1988-01-01 00:00:00

abstract：:Models of pulmonary edema have been used to study the nuclear magnetic resonance (NMR) characteristics of lung water. Several investigators have measured changes in the relaxation times in the permeability type of pulmonary edema, but relatively few have measured relaxation times in the hydrostatic type of pulmonary e...

journal_title：Lung

authors： Shioya S,Tsuji C,Haida M,Fukuzaki M,Tanigaki T,Kurita D,Ohta Y,Yamabayashi H

更新日期：1996-01-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to determine if electrocardiographically synchronized, prospectively triggered multidetector row computed tomography (ECG-MDR-CT) angiography of the aorta can accurately predict the location of ectopic bronchial arteries in patients with cystic fibrosis (CF) with massive hemop...

journal_title：Lung

authors： Hayes D Jr,Winkler MA,Kirkby S,Capasso P,Mansour HM,Attili AK

更新日期：2012-04-01 00:00:00

abstract：:Pleurodesis is a useful therapeutic tool when local treatment of a recurrent malignant pleural effusion or pneumothorax is needed. We have previously demonstrated that the intrapleural injection of 0.5% silver nitrate (SN) produces a significant pleurodesis, while 0.25% SN has no sclerosing effect in a rabbit model. T...

journal_title：Lung

authors： Teixeira LR,Vargas FS,Antonangelo L,Mattos VC,Vaz MA,Acencio MM,Marchi E

更新日期：2003-11-01 00:00:00

abstract：:Bronchial provocation studies performed in our research center have consistently demonstrated airway hyperresponsiveness to both inhaled methacholine and histamine in subjects with chronic cervical spinal cord injury (SCI). More recently, we reported that the airways of such subjects maintained on chronic baclofen (ga...

journal_title：Lung

authors： Grimm DR,DeLuca RV,Lesser M,Bauman WA,Almenoff PL

更新日期：1997-01-01 00:00:00

abstract：:Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...

journal_title：Lung

authors： Keeney SE,Oelberg DG

更新日期：1993-01-01 00:00:00

abstract：:Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and ran...

journal_title：Lung

authors： Abu-Hijleh M,Lee D,Braman SS

更新日期：2008-11-01 00:00:00

abstract：:The transmission of forces from the respiratory muscles to the lung across the extremely thin pleural space has been poorly understood because of the difficulty of accurately measuring pleural liquid and pleural surface pressure (lung static recoil or transpulmonary pressure). Recent results using relatively noninvasi...

journal_title：Lung

authors： Lai-Fook SJ

更新日期：1987-01-01 00:00:00