Isolation of bovine type II pneumocytes in high yield and purity.

abstract：:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is recognized as a preneoplastic condition by the World Health Organization. We reviewed our experience with 30 patients and performed a systematic review of the English literature to collect best evidence on the clinical features and disease cours...

journal_title：Lung

authors： Wirtschafter E,Walts AE,Liu ST,Marchevsky AM

更新日期：2015-10-01 00:00:00

abstract：:This study evaluated the extracellular matrix (collagen and elastic fibers) in pleurodesis induced by intrapleural talc (TL) or silver nitrate (SN). Study subjects were 420 rabbits divided into two groups and sacrificed from 15 min to 12 months after the injection of the sclerosing agents at intervals previously defin...

journal_title：Lung

authors： Antonangelo L,Vargas FS,Teixeira LR,Acencio MM,Vaz MA,Filho MT,Marchi E

更新日期：2006-03-01 00:00:00

abstract：:Cessation of smoking in the home is one of the most important nonpharmacologic actions to be recommended. There is a highly significant increase in wheezing, coughing, and respiratory infections in children with smoking mothers, and this increase is directly proportional to the number of cigarettes smoked. Cord blood ...

journal_title：Lung

authors： Price JA

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...

journal_title：Lung

authors： Ramonell RP,Iftikhar IH

更新日期：2020-02-01 00:00:00

abstract：:Treatment of allergic asthma with inhaled corticosteroids results in local down-regulation of proinflammatory cytokine synthesis and in marked decrease in tissue eosinophilia. Blood concentrations of inhaled corticosteroids, although significantly lower than those measured in the lung, may still have antiinflammatory ...

journal_title：Lung

authors： Lantero S,Oddera S,Silvestri M,Gonzalez Rodriguez R,Morelli MC,Rossi GA

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme 2 (ACE2), an ACE homolog, hydrolyzes angiotensin II and opposes its actions, and plays a protective role in the pathogenesis of pulmonary arterial hypertension (PAH). However, the underlying mechanisms involved in the effect of ACE2 on PAH are still uncertain. In this study, we ...

journal_title：Lung

authors： Li G,Liu Y,Zhu Y,Liu A,Xu Y,Li X,Li Z,Su J,Sun L

更新日期：2013-08-01 00:00:00

abstract：ABSTARCT:New anti-fibrotic agents for idiopathic pulmonary fibrosis (IPF) were approved based on the results of forced vital capacity (FVC) trends, although concerns were raised about the reliability of FVC as the only endpoint parameter. We hypothesized that IPF-specific multi-dimensional scores (Composite Physiologic...

journal_title：Lung

authors： Hosein K,Le J,Mura M

更新日期：2017-02-01 00:00:00

abstract：:A multiuser system for whole body plethysmographic measurements and interpretation which has been developed under clinical conditions is described. The following measurements can be carried out in a rapid way and in one session with the patient: specific airway resistance during spontaneous breathing, determination of...

journal_title：Lung

authors： Zaiss AW,Matthys H

更新日期：1990-01-01 00:00:00

abstract：:Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...

journal_title：Lung

authors： Keeney SE,Oelberg DG

更新日期：1993-01-01 00:00:00

abstract：:Long-term treatment studies with formoterol and salmeterol show that these inhaled long-acting beta 2-agonists compared to available beta 2-agonists produce better bronchodilation, decrease the need for additional doses, decrease asthma symptoms, and are strongly preferred by the patients. Development of tolerance has...

journal_title：Lung

authors： Larsson S

更新日期：1990-01-01 00:00:00

abstract：:Overlap syndrome and represents a complex clinical condition in pulmonary medicine. We discuss in this letter factors related with mortality after long-term effects CPAP and key differences between hypercapnic versus hypoxemic overlap patients. ...

journal_title：Lung

authors： Esquinas AM,Marrero FL,Esteva JN

更新日期：2014-10-01 00:00:00

abstract：INTRODUCTION:The goal of our systematic review and meta-analysis is to examine the therapeutic effectiveness of bronchoscopic lung volume reduction (BLVR), and to compare it with medical management and lung volume reduction surgery. METHODS:Variables of interest were absolute change in FEV1, 6MWT, and SGRQ. Meta-analy...

journal_title：Lung

authors： Kumar A,Dy R,Singh K,Jeffery Mador M

更新日期：2017-02-01 00:00:00

abstract：:The practice of sedation dosing strategy in mechanically ventilated patient has a profound effect on cognitive function. We conducted a comprehensive review of outcome of sedation on mental health function in critically ill patients on mechanical ventilation in the intensive care unit (ICU). We specifically evaluated ...

journal_title：Lung

authors： Porhomayon J,El-Solh AA,Adlparvar G,Jaoude P,Nader ND

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To investigate whether lung function, especially when complicated with SDB, has an increased risk for myocardial infarction (MI) and congestive heart failure (CHF). METHODS:A prospective study was performed within the Sleep Heart Health Study (SHHS). A total of 4161 individuals were followed up for an average ...

journal_title：Lung

authors： Li R,Zhang J,Gao Y,Li J,Yan B,Wang G

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Transbronchial lung biopsy (TBBX) is a common respiratory diagnostic procedure performed to investigate several lung diseases. There are different types of forceps used to perform this procedure. The alligator and cupped (oval) forceps are most commonly used ones. To date, there are few studies that have com...

journal_title：Lung

authors： Almadani A,Ping MNY,Deenadayalu A,Saunders J,O'Brien A

更新日期：2019-02-01 00:00:00

abstract：:We report two patients with atopic cough due to Basidiomycetes antigen. One patient was a 27 year-old woman and the other was a 17 year-old boy. Both patients visited our hospital because of severe nonproductive cough. They did not have bronchial hyperresponsiveness to methacholine or heightened bronchomotor tone. Bro...

journal_title：Lung

authors： Ogawa H,Fujimura M,Tofuku Y

更新日期：2004-01-01 00:00:00

abstract：:Isoniazid (INH) is one of the most important first line drugs in the treatment of tuberculosis. We utilized high performance liquid chromatography with a hydrazone extraction technique to measure INH in bronchoalveolar lavage (BAL) fluid specimens from six patients with active pulmonary tuberculosis. We found BAL flui...

journal_title：Lung

authors： O'Brien JK,Doerfler ME,Harkin TJ,Rom WN

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:There is very little evidence of the utility of the exhaled fraction of NO (FeNO) for the diagnosis of interstitial lung disease and nearly all of it is related with connective tissue disease. Some authors have suggested that in patients with hypersensitivity pneumonitis (HP), evolution to pulmonary fibrosis...

journal_title：Lung

authors： Ojanguren I,Cruz MJ,Villar A,Barrecheguren M,Morell F,Muñoz X

更新日期：2016-02-01 00:00:00

abstract：:Myofibroblasts characterized by alpha smooth muscle actin(alpha-SMA) expression play a key role in pulmonary fibrosis. Transforming growth factor-beta1 (TGF-beta1) is likely to be involved in the emergence of myofibroblasts, but the intracellular signal pathways for this process have not been well determined. The aim ...

journal_title：Lung

authors： Hu Y,Peng J,Feng D,Chu L,Li X,Jin Z,Lin Z,Zeng Q

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcomes. This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five-year period. Further, we compared our results to the 'World Association of Sarcoi...

journal_title：Lung

authors： Markevitz N,Epstein Shochet G,Levi Y,Israeli-Shani L,Shitrit D

更新日期：2017-08-01 00:00:00

abstract：:Undifferentiated connective tissue disease (UCTD) is a distinct clinical entity that may be accompanied by interstitial lung disease (ILD). The natural history of UCTD-ILD is unknown. We hypothesized that patients with UCTD-ILD would be more likely to have improvement in lung function than those with idiopathic pulmon...

journal_title：Lung

authors： Kinder BW,Shariat C,Collard HR,Koth LL,Wolters PJ,Golden JA,Panos RJ,King TE Jr

更新日期：2010-04-01 00:00:00

abstract：:Simulation-based medical education has gained tremendous popularity over the past two decades. Driven by the patient safety movement, changes in the educational opportunities available to trainees and the rapidly evolving capabilities of computer technology, simulation-based medical education is now being used across ...

journal_title：Lung

authors： Lam G,Ayas NT,Griesdale DE,Peets AD

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Exercising or doing physical activity in polluted air could expose a person to the adverse health effects of air pollution. This study aimed to compare the cardiovascular and hematologic indices following an incremental exercise test (shuttle run) under clean versus polluted air conditions. METHODS:Nineteen ma...

journal_title：Lung

authors： Kargarfard M,Shariat A,Shaw BS,Shaw I,Lam ET,Kheiri A,Eatemadyboroujeni A,Tamrin SB

更新日期：2015-04-01 00:00:00

abstract：:Electronic noses (e-noses) are based on arrays of different sensor types that respond to specific features of an odorant molecule, mostly volatile organic compounds (VOCs). Differently from gas chromatography and mass spectrometry, e-noses can distinguish VOCs spectrum by pattern recognition. E-nose technology has suc...

journal_title：Lung

authors： Dragonieri S,Pennazza G,Carratu P,Resta O

更新日期：2017-04-01 00:00:00

abstract：:Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...

journal_title：Lung

authors： Vantaggiato L,Perruzza M,Refini RM,Bergantini L,d'Alessandro M,Cameli P,Perruzza D,Bini L,Bargagli E,Landi C

更新日期：2020-10-01 00:00:00

abstract：:Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...

journal_title：Lung

authors： Manalo E,Merritt TA,Amirkhanian JD,Kheiter A

更新日期：1997-01-01 00:00:00

abstract：:Lung elastance and resistance increase in the supine posture. To evaluate the effects of change in posture on regional lung mechanics at different lung volumes, lung elastance and resistance were measured at graded volume subdivisions and three esophageal levels at seated and supine body positions, using the esophagea...

journal_title：Lung

authors： Baydur A,Sassoon CS,Carlson M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Cardiopulmonary exercise testing (CPET) is a safe and clinically useful method to assess functional capacity and to follow disease progression and the response to treatment in several clinical conditions. AIM:We set out to determine the relationship between outcome measures of CPET and high-resolution compu...

journal_title：Lung

authors： Lopes AJ,de Menezes SL,Dias CM,de Oliveira JF,Mainenti MR,Guimarães FS

更新日期：2011-10-01 00:00:00

abstract：:Respiratory adaptation during sleep improves with growth. The most vulnerable period for respiratory adaptation to sleep is from birth to 3 months of age. Factors that favor vulnerability are immaturity in ventilatory control and high rib cage compliance which impairs its effectiveness for ventilation. Improvement in ...

journal_title：Lung

authors： Gaultier C

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Idiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies to alveolar epithelial and endothelial cells may be involved in the p...

journal_title：Lung

authors： Fahim A,Chong MC,Crooks MG,Hart SP

更新日期：2012-08-01 00:00:00