Abstract：
:Three major white matter pathways connect the posterior temporal region and the adjacent inferior parietal lobule with the lateral frontal cortex: the arcuate fasciculus (AF), and the second and third branches of the superior longitudinal fasciculus (SLF II and SLF III). These pathways are found also in nonhuman primate brains where they play specific roles in auditory and spatial processing. The precise origin, course, and termination of these pathways has been examined in invasive tract tracing studies in macaque monkeys. Here we use this prior knowledge to improve dissections of these pathways in vivo in the human brain using diffusion Magnetic Resonance Imaging (MRI) tractography. In this study, the AF, originating from the posterior temporal cortex, has been successfully separated from the SLF II and SLF III tracts originating from the angular and supramarginal gyri of the inferior parietal lobule, respectively. The latter two pathways, i.e. SLF II and SLF III, have also been clearly separated from each other. Furthermore, we report for the first time in the human brain the dorsal branch of the AF that targets the posterior dorsolateral frontal region. These improved dissection protocols provide a solid basis for exploring the respective functional roles of these major fasciculi.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Barbeau EB,Descoteaux M,Petrides Mdoi
10.1038/s41598-020-64124-ysubject
Has Abstractpub_date
2020-05-18 00:00:00pages
8186issue
1issn
2045-2322pii
10.1038/s41598-020-64124-yjournal_volume
10pub_type
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