G9a inhibits MEF2C activity to control sarcomere assembly.

abstract：:Camouflage has been a textbook example of natural selection and adaptation since the time of the earliest evolutionists. However, aside from correlational evidence and studies using artificial dummy prey, experiments directly showing that better camouflaged prey to predator vision are at reduced risk of attack are lac...

journal_title：Scientific reports

authors： Duarte RC,Stevens M,Flores AAV

更新日期：2018-10-30 00:00:00

abstract：:In many human cancers, including hepatocellular carcinoma (HCC), high density of infiltrating tumor-associated macrophages (TAM) is associated with poor prognosis. Most TAMs express a M2 phenotype subsequently supporting tumor growth. How tumor cells polarize these TAMs to a pro-tumor M2 phenotype is still poorly unde...

journal_title：Scientific reports

authors： Shiau DJ,Kuo WT,Davuluri GVN,Shieh CC,Tsai PJ,Chen CC,Lin YS,Wu YZ,Hsiao YP,Chang CP

更新日期：2020-08-12 00:00:00

abstract：:The central challenge in realizing non-volatile, E-field manipulation of magnetism lies in finding an energy efficient means to switch between the distinct magnetic states in a stable and reversible manner. In this work, we demonstrate using electrical polarization-induced charge screening to change the ground state o...

journal_title：Scientific reports

authors： Zhou Z,Howe BM,Liu M,Nan T,Chen X,Mahalingam K,Sun NX,Brown GJ

更新日期：2015-01-13 00:00:00

abstract：:Previous research has shown that low-level visual features (i.e., low-level visual saliency) as well as socially relevant information predict gaze allocation in free viewing conditions. However, these studies mainly used static and highly controlled stimulus material, thus revealing little about the robustness of atte...

journal_title：Scientific reports

authors： Rubo M,Gamer M

更新日期：2018-02-28 00:00:00

abstract：:Nanotips made of metal and semiconductor have been widely utilized in versatile applications to strengthen the electric field through lightning rod effect and localized surface plasmon resonance (LSPR) effect. Here, we present the utilization of ferroelectric nanotips to assist photoreduction of silver nanostructures ...

journal_title：Scientific reports

authors： Wang TJ,Chang HW,Chen JS,Chiang HP

更新日期：2019-07-29 00:00:00

abstract：:The queens of eusocial bees, ants and wasps mate only during a very short period early in life and males therefore produce ejaculates consisting of large numbers of high quality sperm. Such extreme selection for high fecundity resulted in males investing minimally into their somatic survival, including their immune sy...

journal_title：Scientific reports

authors： Peng Y,Baer-Imhoof B,Millar AH,Baer B

更新日期：2015-06-30 00:00:00

abstract：:Pre-stimulus alpha (8-12 Hz) and beta (16-20 Hz) oscillations have been frequently linked to the prediction of upcoming sensory input. Do these frequency bands serve as a neural marker of linguistic prediction as well? We hypothesized that if pre-stimulus alpha and beta oscillations index language predictions, their p...

journal_title：Scientific reports

authors： Terporten R,Schoffelen JM,Dai B,Hagoort P,Kösem A

更新日期：2019-12-27 00:00:00

abstract：:In 2018, the World Health Organization identified the Zika virus (ZIKV) as a pathogen that should be prioritized for public health research due to its epidemic potential. In this study, whole-genome sequencing (WGS) of travel-acquired ZIKV infections was used to examine the limitations of phylogenetic analysis. WGS an...

journal_title：Scientific reports

authors： Kamelian K,Montoya V,Olmstead A,Dong W,Harrigan R,Morshed M,Joy JB

更新日期：2019-11-11 00:00:00

abstract：:Microbial secondary metabolites are valuable resources for novel drug discovery. In particular, actinomycetes expressed a range of antibiotics against a spectrum of bacteria. In genus level, strain Allosalinactinospora lopnorensis CA15-2(T) is the first new actinomycete isolated from the Lop Nor region, China. Antimic...

journal_title：Scientific reports

authors： Huang C,Leung RK,Guo M,Tuo L,Guo L,Yew WW,Lou I,Lee SMY,Sun C

更新日期：2016-02-11 00:00:00

abstract：:Great interest has been shown in mesenchymal stem cell (MSC) therapy in a wide variety of clinical domains. However, the therapeutic efficiency depends on the proliferation and migration of MSCs. Chemokine receptors are involved in regulating the proliferation and migration to the specific organs of MSCs in different ...

journal_title：Scientific reports

authors： Liu L,Chen JX,Zhang XW,Sun Q,Yang L,Liu A,Hu S,Guo F,Liu S,Huang Y,Yang Y,Qiu HB

更新日期：2018-01-09 00:00:00

abstract：:Innate immunity has been extended to respond environmental pathogen other than microbial components. Here we explore a novel pollen/TLR4 innate immunity in allergic inflammation. In experimental allergic conjunctivitis induced by short ragweed (SRW) pollen, typical allergic signs, stimulated IL-33/ST2 signaling and ov...

journal_title：Scientific reports

authors： Li J,Zhang L,Chen X,Chen D,Hua X,Bian F,Deng R,Lu F,Li Z,Pflugfelder SC,Li DQ

更新日期：2016-10-31 00:00:00

abstract：:Seed size/weight is a major agronomic trait which determine crop productivity in legumes. To understand the genetic basis of seed size determination, we sought to identify DNA polymorphisms between two small (Himchana 1 and Pusa 362) and two large-seeded (JGK 3 and PG 0515) chickpea cultivars via whole genome resequen...

journal_title：Scientific reports

authors： Rajkumar MS,Garg R,Jain M

更新日期：2018-11-14 00:00:00

abstract：:Present study focuses on rainfall over Western Ghats (WG), a complex topographic region (elevation > 500 m) of India to evaluate and to better understand the satellite behavior in contrast with a flat region (FR) (elevation < 500 m) of central India from 1998 to 2016 using the combinatory data sets of TMPA and IMERG (...

journal_title：Scientific reports

authors： Thakur MK,Kumar TVL,Koteswara Rao K,Barbosa H,Rao VB

更新日期：2019-10-30 00:00:00

abstract：:The evolution of sexual reproduction remains a fascinating enigma in biology. Theoretically, populations of sexual organisms investing half of their resources into producing male offspring that don't contribute to reproduction should grow at only half the rate of their asexual counterparts. This demographic disadvanta...

journal_title：Scientific reports

authors： Kobayashi K,Hasegawa E

更新日期：2016-04-01 00:00:00

abstract：:Crohn's disease (CD) has been associated with an increased consumption of n-6 polyunsaturated fatty acid (PUFA), while greater intake of n-3 PUFA has been associated with a reduced risk. We sought to investigate serum fatty acid composition in CD, and associations of fatty acids with disease activity, cytokines, and a...

journal_title：Scientific reports

authors： Scoville EA,Allaman MM,Adams DW,Motley AK,Peyton SC,Ferguson SL,Horst SN,Williams CS,Beaulieu DB,Schwartz DA,Wilson KT,Coburn LA

更新日期：2019-02-27 00:00:00

abstract：:Mathematical modelling has been widely used to predict the effects of perturbations to brain networks. An important example is epilepsy surgery, where the perturbation in question is the removal of brain tissue in order to render the patient free of seizures. Different dynamical models have been proposed to represent ...

journal_title：Scientific reports

authors： Junges L,Lopes MA,Terry JR,Goodfellow M

更新日期：2019-05-14 00:00:00

abstract：:Our study aimed to investigate the effect of Pap smear screening on stage at diagnosis of cervical cancer in a heterogeneous population of Thai women. Data was merged from the population-based cancer registry and screening registry based on unique identification numbers from 2006 to 2014. Patients being screened had l...

journal_title：Scientific reports

authors： Niu L,Virani S,Bilheem S,Sriplung H

更新日期：2019-11-15 00:00:00

abstract：:Fibroblast growth factor-21 (FGF21) is closely related to various metabolic and cardiovascular disorders. However, the direct targets and mechanisms linking FGF21 to blood pressure control and hypertension are still elusive. Here we demonstrated a novel regulatory function of FGF21 in the baroreflex afferent pathway (...

journal_title：Scientific reports

authors： He JL,Zhao M,Xia JJ,Guan J,Liu Y,Wang LQ,Song DX,Qu MY,Zuo M,Wen X,Yu X,Huo R,Pan ZW,Ban T,Zhang Y,Zhu JX,Shou W,Qiao GF,Li BY

更新日期：2016-07-08 00:00:00

abstract：:The advantages of the digital PCR technology are already well documented until now. One way to achieve better cost efficiency of the technique is to use it in a multiplexing strategy. Droplet digital PCR platforms, which include two fluorescence filters, support at least duplex reactions and with some developments and...

journal_title：Scientific reports

authors： Dobnik D,Štebih D,Blejec A,Morisset D,Žel J

更新日期：2016-10-14 00:00:00

abstract：:An on-going debate concerning the dietary adaptations of archaic hominins and early Homo has been fuelled by contradictory inferences obtained using different methodologies. This work presents an extensive comparative sample of 30 extant primate species that was assembled to perform a morpho-functional comparison of t...

journal_title：Scientific reports

authors： Marcé-Nogué J,Püschel TA,Daasch A,Kaiser TM

更新日期：2020-04-22 00:00:00

abstract：:Aconiti Lateralis Radix Praeparata (Fuzi) is obtained from processed daughter roots of Aconitum carmichaeli, a toxic plant with a high medical value well known in Chinese medicine. In addition to the known toxic alkaloids (aconitine, mesaconitine, and hypaconitine) and bioactive alkaloids (benzoylaconine, benzoylmesac...

journal_title：Scientific reports

authors： He F,Wang CJ,Xie Y,Cheng CS,Liu ZQ,Liu L,Zhou H

更新日期：2017-10-12 00:00:00

abstract：:This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30 young obese non-diabetic (23.90 ± 3.84 years and BMI ...

journal_title：Scientific reports

authors： Garcés MF,Buell-Acosta JD,Rodríguez-Navarro HA,Pulido-Sánchez E,Rincon-Ramírez JJ,Moreno-Ordóñez DC,Franco-Vega R,Roncancio-Muñoz JS,Burgos-Cardenas AJ,Lacunza E,Castaño JP,Diéguez C,Nogueiras R,Sanchez E,Caminos JE

更新日期：2020-12-03 00:00:00

abstract：:Advanced fibrosis and portal hypertension influence short-term mortality. Lipocalin 2 (LCN2) regulates infection response and increases in liver injury. We explored the role of intrahepatic LCN2 in human alcoholic hepatitis (AH) with advanced fibrosis and portal hypertension and in experimental mouse fibrosis. We foun...

journal_title：Scientific reports

authors： Chen J,Argemi J,Odena G,Xu MJ,Cai Y,Massey V,Parrish A,Vadigepalli R,Altamirano J,Cabezas J,Gines P,Caballeria J,Snider N,Sancho-Bru P,Akira S,Rusyn I,Gao B,Bataller R

更新日期：2020-09-23 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:Since the world population is ageing, dementia is going to be a growing concern. Alzheimer's disease is the most common form of dementia. The pathogenesis of Alzheimer's disease is extensively studied, yet unknown remains. Therefore, we aimed to extract new knowledge from existing data. We analysed about 2700 upregula...

journal_title：Scientific reports

authors： Hosseinian S,Arefian E,Rakhsh-Khorshid H,Eivani M,Rezayof A,Pezeshk H,Marashi SA

更新日期：2020-05-20 00:00:00

abstract：:Either hardness or toughness has been the core interest in scientific exploration and technological pursuit for a long time. However, it is still a big challenge to enhance the hardness and toughness at the same time, since the improvement of one side is always at the expense of the other one. Here, we have succeeded ...

journal_title：Scientific reports

authors： Yang L,Zhang K,Wen M,Hou Z,Gong C,Liu X,Hu C,Cui X,Zheng W

更新日期：2017-08-24 00:00:00

abstract：:The recombination is one of the most frequently identified drivers of double-stranded DNA viruses evolution. However, the recombination events in African swine fever virus (ASFV) genomes have been poorly annotated. We hypothesize that the genetic determinants of ASFV variability are potential hot-spots for recombinati...

journal_title：Scientific reports

authors： Nefedeva M,Titov I,Tsybanov S,Malogolovkin A

更新日期：2020-10-28 00:00:00

abstract：:Solar conversion to fuels or to electricity in semiconductors using far red-to-near infrared (NIR) light, which accounts for about 40% of solar energy, is highly significant. One main challenge is the development of novel strategies for activity promotion and new basic mechanisms for NIR response. Mother Nature has ev...

journal_title：Scientific reports

authors： Yan R,Chen M,Zhou H,Liu T,Tang X,Zhang K,Zhu H,Ye J,Zhang D,Fan T

更新日期：2016-01-28 00:00:00

abstract：:Volumetric and morphometric studies have demonstrated structural abnormalities related to chronic epilepsies on a cohort- and population-based level. On a single-patient level, specific patterns of atrophy or cortical reorganization may be widespread and heterogeneous but represent potential targets for further person...

journal_title：Scientific reports

authors： Rummel C,Slavova N,Seiler A,Abela E,Hauf M,Burren Y,Weisstanner C,Vulliemoz S,Seeck M,Schindler K,Wiest R

更新日期：2017-09-07 00:00:00

abstract：:PP2A is a master controller of multiple inflammatory signaling pathways. It is a target in asthma; however the molecular mechanisms by which PP2A controls inflammation warrant further investigation. In A549 lung epithelial cells in vitro we show that inhibition of basal PP2A activity by okadaic acid (OA) releases rest...

journal_title：Scientific reports

authors： Rahman MM,Rumzhum NN,Morris JC,Clark AR,Verrills NM,Ammit AJ

更新日期：2015-05-18 00:00:00