FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats.

abstract：:The westerly wind burst (WWB) is an important triggering mechanism of El Niño and typically occurs in the western Pacific Ocean. The Fourier spectrum of the wind field over the western tropical Pacific is characterised by a large variety of peaks distributed from intra-seasonal to decadal time scales, suggesting that ...

journal_title：Scientific reports

authors： Sullivan A,Zhong W,Borzelli GLE,Geng T,Mackallah C,Ng B,Hong CC,Cai W,Huang AY,Bodman R

更新日期：2021-01-13 00:00:00

abstract：:We introduce multi-gradients including Laplace pressure gradient, wettable gradient and wettable different gradient on a high adhesion surface via special wedge-pattern and improved anodic oxidation method. As a result of the cooperative effect mentioned above, controlled directional motion of a droplet on a high adhe...

journal_title：Scientific reports

authors： Deng S,Shang W,Feng S,Zhu S,Xing Y,Li D,Hou Y,Zheng Y

更新日期：2017-04-03 00:00:00

abstract：:The present study investigates the impact of charge variants on bevacizumab's structure, stability, and biological activity. Five basic and one acidic charge variants were separated using semi-preparative cation exchange chromatography using linear pH gradient elution with purity > 85%. Based on the commercial biosimi...

journal_title：Scientific reports

authors： Singh SK,Kumar D,Malani H,Rathore AS

更新日期：2021-01-29 00:00:00

abstract：:NF-κB signaling pathway has important roles in the regulation of growth and development of nervous system. This pathway has also been shown to participate in the pathogenesis of schizophrenia. Meanwhile, activity of NF-κB signaling pathway is regulated by several factors including non-coding RNAs (lncRNAs). In the cur...

journal_title：Scientific reports

authors： Safa A,Badrlou E,Arsang-Jang S,Sayad A,Taheri M,Ghafouri-Fard S

更新日期：2020-10-22 00:00:00

abstract：:In spin-based nanosystems for quantum information processing, electron spin qubits are subject to decoherence due to their interactions with nuclear spin environments. In this paper, we present an exact master equation for a central spin-1/2 system in time-dependent external fields and coupled to a spin-half bath in t...

journal_title：Scientific reports

authors： Jing J,Wu LA

更新日期：2018-01-24 00:00:00

abstract：:Survivors of childhood acute lymphoblastic leukemia (cALL) are at higher risk of developing cardiometabolic complications. We aimed at exploring the associations between biomarkers of inflammation, oxidative stress, endothelial function, endotoxemia and cardiometabolic risk factors. We conducted a cross-sectional anal...

journal_title：Scientific reports

authors： Morel S,Léveillé P,Samoilenko M,Franco A,England J,Malaquin N,Tu V,Cardin GB,Drouin S,Rodier F,Lippé S,Krajinovic M,Laverdière C,Sinnett D,Lefebvre G,Levy E,Marcil V

更新日期：2020-12-09 00:00:00

abstract：:FGF10 is a member of fibroblast growth factors (FGFs). We previously showed that FGF10 protects neuron against oxygen-glucose deprivation injury in vitro; however, the effect of FGF10 in ischemic stroke in vivo is unknown. In the present study, we showed that FGF10 was mainly expressed in neurons but not astrocytes, a...

journal_title：Scientific reports

authors： Li YH,Fu HL,Tian ML,Wang YQ,Chen W,Cai LL,Zhou XH,Yuan HB

更新日期：2016-01-27 00:00:00

abstract：:Marine crabs inhabit shallow coastal/estuarine habitats particularly sensitive to climate change, and yet we know very little about the diversity of their responses to environmental change. We report the effects of a rarely studied, but increasingly prevalent, combination of environmental factors, that of near-future ...

journal_title：Scientific reports

authors： Whiteley NM,Suckling CC,Ciotti BJ,Brown J,McCarthy ID,Gimenez L,Hauton C

更新日期：2018-10-23 00:00:00

abstract：:Atlantic bluefin tuna (Thunnus thynnus) from the two main spawning populations in the Mediterranean and Gulf of Mexico occur together in the western, central and eastern Atlantic. Stock composition of catches from mixing areas is uncertain, presenting a major challenge to the sustainable management of the fisheries. T...

journal_title：Scientific reports

authors： Brophy D,Rodríguez-Ezpeleta N,Fraile I,Arrizabalaga H

更新日期：2020-09-07 00:00:00

abstract：:We report on the optical and structural characterization of rubrene polycrystalline films fabricated from vacuum deposition with various substrate temperatures (Tsub). Depending on Tsub, the role of twisted and planar rubrene conformational isomers on the properties of rubrene films is focused. The temperature (T)-dep...

journal_title：Scientific reports

authors： Lin KY,Wang YJ,Chen KL,Ho CY,Yang CC,Shen JL,Chiu KC

更新日期：2017-01-16 00:00:00

abstract：:BST-2/tetherin is an interferon-inducible antiviral protein that blocks the release of various enveloped viruses, including HIV-1. Hepatitis B virus (HBV), a major cause of liver disease, belongs to the Hepadnaviridae family of enveloped DNA viruses. Whether BST-2 regulates HBV production is largely unknown. In this r...

journal_title：Scientific reports

authors： Lv M,Zhang B,Shi Y,Han Z,Zhang Y,Zhou Y,Zhang W,Niu J,Yu XF

更新日期：2015-06-29 00:00:00

abstract：:Thermodynamics is a branch of science blessed by an unparalleled combination of generality of scope and formal simplicity. Based on few natural assumptions together with the four laws, it sets the boundaries between possible and impossible in macroscopic aggregates of matter. This triggered groundbreaking achievements...

journal_title：Scientific reports

authors： Correa LA,Palao JP,Alonso D,Adesso G

更新日期：2014-02-04 00:00:00

abstract：:The characterization of fully-defined in vitro hepatic culture systems requires testing of functional and morphological variables to obtain the optimal trophic support, particularly for cell therapeutics including bioartificial liver systems (BALs). Using serum-free fully-defined culture medium formulations, we measur...

journal_title：Scientific reports

authors： Nelson LJ,Treskes P,Howie AF,Walker SW,Hayes PC,Plevris JN

更新日期：2013-01-01 00:00:00

abstract：:Harnessing complement-mediated cytotoxicity by therapeutic antibodies has been limited because of dependency on size and density of antigen, structural constraints resulting from orientation of antibody binding, and blockade of complement activation by inhibitors expressed on target cells. We developed a modular bispe...

journal_title：Scientific reports

authors： Cruz JW,Damko E,Modi B,Tu N,Meagher K,Voronina V,Gartner H,Ehrlich G,Rafique A,Babb R,Aneja P,Potocky TB,D' Orvilliers A,Coppi A,E SY,Qiu H,Williams CM,Bennett BL,Chen G,Macdonald L,Olson W,Lin JC,Stahl N,Mu

更新日期：2019-08-19 00:00:00

abstract：:Stable isotopes in water (e.g., δ2H and δ18O) are important indicators of hydrological and ecological patterns and processes. Tap water can reflect integrated features of regional hydrological processes and human activities. China is a large country with significant meteorological and geographical variations. This rep...

journal_title：Scientific reports

authors： Zhao S,Hu H,Tian F,Tie Q,Wang L,Liu Y,Shi C

更新日期：2017-03-02 00:00:00

abstract：:Structural materials used for safety critical applications require high strength and simultaneously high resistance against crack growth, referred to as damage tolerance. However, the two properties typically exclude each other and research efforts towards ever stronger materials are hampered by drastic loss of fractu...

journal_title：Scientific reports

authors： Hohenwarter A,Völker B,Kapp MW,Li Y,Goto S,Raabe D,Pippan R

更新日期：2016-09-14 00:00:00

abstract：:The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Her...

journal_title：Scientific reports

authors： Cao JM,Cheng XN,Li SQ,Heller S,Xu ZG,Shi DL

更新日期：2016-11-08 00:00:00

abstract：:The association between maternal cadmium (Cd) exposure during pregnancy and the increased risk of fetal growth restriction (FGR) remains controversial. The present study evaluated the association between maternal serum Cd level and risk of small for gestational age (SGA) infants in a Chinese population. The present st...

journal_title：Scientific reports

authors： Wang H,Liu L,Hu YF,Hao JH,Chen YH,Su PY,Fu L,Yu Z,Zhang GB,Wang L,Tao FB,Xu DX

更新日期：2016-03-03 00:00:00

abstract：:The phylogenetic characteristics of microbial communities associated with periodontitis have been well studied, however, little is known about the functional endowments of this ecosystem. The present study examined 73 microbial assemblages from 25 individuals with generalized chronic periodontitis and 25 periodontally...

journal_title：Scientific reports

authors： Dabdoub SM,Ganesan SM,Kumar PS

更新日期：2016-12-19 00:00:00

abstract：:The genetic sexing of animals having long gestation periods offers significant benefits in regard to breeding management among their populations living in captivity. In our study, a new increased-sensitivity PCR method for fetal sexing was developed and tested successfully on elephants, from only a small volume of mat...

journal_title：Scientific reports

authors： Vincze B,Gáspárdy A,Biácsi A,Papp EÁ,Garamvölgyi L,Sós E,Cseh S,Kovács G,Pádár Z,Zenke P

更新日期：2019-10-24 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Kim KG,Kim SY

更新日期：2019-04-16 00:00:00

abstract：:Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs), a typical antioxida...

journal_title：Scientific reports

authors： Fujitani N,Yoneda A,Takahashi M,Takasawa A,Aoyama T,Miyazaki T

更新日期：2019-10-14 00:00:00

abstract：:The ability to form mineral structures under biological control is widespread among animals. In several species, specific proteins have been shown to be involved in biomineralization, but it is uncertain how they influence the shape of the growing biomineral and the resulting skeleton. Calcareous sponges are the only ...

journal_title：Scientific reports

authors： Voigt O,Adamska M,Adamski M,Kittelmann A,Wencker L,Wörheide G

更新日期：2017-04-13 00:00:00

abstract：:Generation of multiple mRNAs by alternative splicing is well known in the group of cytokines and has recently been reported for the human erythropoietin (EPO) gene. Here, we focus on the alternatively spliced EPO transcript characterized by deletion of exon 3 (hEPOΔ3). We show co-regulation of EPO and hEPOΔ3 in human ...

journal_title：Scientific reports

authors： Bonnas C,Wüstefeld L,Winkler D,Kronstein-Wiedemann R,Dere E,Specht K,Boxberg M,Tonn T,Ehrenreich H,Stadler H,Sillaber I

更新日期：2017-06-16 00:00:00

abstract：:Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system. However, the mechanisms underlying its tumor initiation, progression, and metastasis are not yet fully understood. The annexin A4 (ANXA4) gene is highly expressed in GBC tissues and may play an important role in the initiation and progr...

journal_title：Scientific reports

authors： Yao HS,Sun C,Li XX,Wang Y,Jin KZ,Zhang XP,Hu ZQ

更新日期：2016-08-05 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is a difficult-to-treat infection. Increasing efforts have been taken to mitigate the epidemics and to avoid potential outbreaks in low endemic settings. Understanding the population dynamics of MRSA is essential to identify the causal mechanisms driving the epidemics...

journal_title：Scientific reports

authors： Rocha LEC,Singh V,Esch M,Lenaerts T,Liljeros F,Thorson A

更新日期：2020-06-09 00:00:00

abstract：:We study the impact of light on the mammalian circadian system using the theory of phase response curves. Using a recently developed ansatz we derive a low-dimensional macroscopic model for the core circadian clock in mammals. Significantly, the variables and parameters in our model have physiological interpretations ...

journal_title：Scientific reports

authors： Hannay KM,Forger DB,Booth V

更新日期：2020-11-11 00:00:00

abstract：:Hysteresis, which is the history dependence of physical systems, is one of the most important topics in physics. Interestingly, bi-stability of plasma with a huge hysteresis loop has been observed in inductive plasma discharges. Despite long plasma research, how this plasma hysteresis occurs remains an unresolved ques...

journal_title：Scientific reports

authors： Lee HC,Chung CW

更新日期：2015-10-20 00:00:00

abstract：:This paper reports the fabrication and operation of a transmission-type polarization rotator for visible light with a wavelength of 450 nm using indirect-transition-type semiconductor crystalline SiC in which Al atoms were implanted as a p-type dopant. A novel dressed-photon-phonon (DPP)-assisted annealing method was ...

journal_title：Scientific reports

authors： Kadowaki T,Kawazoe T,Ohtsu M

更新日期：2020-07-31 00:00:00

abstract：:A variety of post-translational modifications of Plasmodium falciparum proteins, including phosphorylation and ubiquitination, are shown to have key regulatory roles during parasite development. NEDD8 is a ubiquitin-like modifier of cullin-RING E3 ubiquitin ligases, which regulates diverse cellular processes. Although...

journal_title：Scientific reports

authors： Bhattacharjee M,Adhikari N,Sudhakar R,Rizvi Z,Das D,Palanimurugan R,Sijwali PS

更新日期：2020-11-19 00:00:00