Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivation.

abstract：:Compact and power-efficient plastic electronic synapses are of fundamental importance to overcoming the bottlenecks of developing a neuromorphic chip. Memristor is a strong contender among the various electronic synapses in existence today. However, the speeds of synaptic events are relatively slow in most attempts at...

journal_title：Scientific reports

authors： Li Y,Zhong Y,Xu L,Zhang J,Xu X,Sun H,Miao X

更新日期：2013-01-01 00:00:00

abstract：:A multi-agent Parrondo's model based on complex networks is used in the current study. For Parrondo's game A, the individual interaction can be categorized into five types of behavioral patterns: the Matthew effect, harmony, cooperation, poor-competition-rich-cooperation and a random mode. The parameter space of Parro...

journal_title：Scientific reports

authors： Ye Y,Cheong KH,Cen YW,Xie NG

更新日期：2016-11-15 00:00:00

abstract：:The networks of predator-prey interactions in ecological systems are remarkably complex, but nevertheless surprisingly stable in terms of long term persistence of the system as a whole. In order to understand the mechanism driving the complexity and stability of such food webs, we developed an eco-evolutionary model i...

journal_title：Scientific reports

authors： Allhoff KT,Ritterskamp D,Rall BC,Drossel B,Guill C

更新日期：2015-06-04 00:00:00

abstract：:The presenilin 1 (PSEN1) L271V mutation causes early-onset familial Alzheimer's disease by disrupting the alternative splicing of the PSEN1 gene, producing some transcripts harboring the L271V point mutation and other transcripts lacking exon 8 (PS1(∆exon8)). We previously reported that PS1 L271V increased amyloid bet...

journal_title：Scientific reports

authors： Brautigam H,Moreno CL,Steele JW,Bogush A,Dickstein DL,Kwok JB,Schofield PR,Thinakaran G,Mathews PM,Hof PR,Gandy S,Ehrlich ME

更新日期：2015-11-26 00:00:00

abstract：:Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels suggested dysregula...

journal_title：Scientific reports

authors： Olie CS,van der Wal E,Domagoj C,Maton L,de Greef JC,Lin IH,Chen YF,Kareem E,Penninger JM,Kessler BM,Raz V

更新日期：2020-10-19 00:00:00

abstract：:Papain-like cysteine proteases (PLCPs) are a class of proteolytic enzymes involved in many plant processes. Compared with the extensive research in Arabidopsis thaliana, little is known in castor bean (Ricinus communis) and physic nut (Jatropha curcas), two Euphorbiaceous plants without any recent whole-genome duplica...

journal_title：Scientific reports

authors： Zou Z,Huang Q,Xie G,Yang L

更新日期：2018-01-10 00:00:00

abstract：:Modern Computed Tomography (CT) scanners are capable of acquiring contrast dynamics of the whole brain, adding functional to anatomical information. Soft tissue segmentation is important for subsequent applications such as tissue dependent perfusion analysis and automated detection and quantification of cerebral patho...

journal_title：Scientific reports

authors： Manniesing R,Oei MTH,Oostveen LJ,Melendez J,Smit EJ,Platel B,Sánchez CI,Meijer FJA,Prokop M,van Ginneken B

更新日期：2017-03-09 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:The 14-3-3-related protein SMG7 plays critical roles in regulation of DNA damage response and nonsense-mediated mRNA decay (NMD). Like 14-3-3, SMG7 engages phosphoserine-dependent protein interactions; however, the precise role of phosphorylation-mediated SMG7 binding remains unknown. Here, we show that DNA damage-ind...

journal_title：Scientific reports

authors： Cowen LE,Luo H,Tang Y

更新日期：2019-09-11 00:00:00

abstract：:Oxidovanadium complexes with organic ligands are well known to have cytotoxic or differentiating capabilities against a range of cancer cell types. Their limited use in clinical testing though has resulted largely from uncertainties about the long-term toxicities of such complexes, due in part to the speciation to van...

journal_title：Scientific reports

authors： Irving E,Tagalakis AD,Maeshima R,Hart SL,Eaton S,Lehtonen A,Stoker AW

更新日期：2020-10-07 00:00:00

abstract：:Epithelial ovarian cancer is a leading cause of death in gynecological cancers. While several systematic studies have revealed the mutation landscape of serous epithelial ovarian cancer, other non-serous subtypes of the disease have not been explored as extensively. Here we conduct exome sequencing of nine non-serous ...

journal_title：Scientific reports

authors： Teer JK,Yoder S,Gjyshi A,Nicosia SV,Zhang C,Monteiro ANA

更新日期：2017-08-29 00:00:00

abstract：:SLC10A7 represents an orphan member of the Solute Carrier Family SLC10. Recently, mutations in the human SLC10A7 gene were associated with skeletal dysplasia, amelogenesis imperfecta, and decreased bone mineral density. However, the exact molecular function of SLC10A7 and the mechanisms underlying these pathologies ar...

journal_title：Scientific reports

authors： Karakus E,Wannowius M,Müller SF,Leiting S,Leidolf R,Noppes S,Oswald S,Diener M,Geyer J

更新日期：2020-04-29 00:00:00

abstract：:Body weight (BW) is regulated in age-dependent manner; it continues to increase during growth period, and reaches a plateau once reaching adulthood. However, its underlying mechanism remains unknown. Regarding such mechanisms in the brain, we here report that neural circuits from the hypothalamus (paraventricular nucl...

journal_title：Scientific reports

authors： Maejima Y,Kato S,Horita S,Ueta Y,Takenoshita S,Kobayashi K,Shimomura K

更新日期：2019-12-04 00:00:00

abstract：:Patients hospitalised with COVID-19 have a high mortality. Identification of patients at increased risk of adverse outcome would be important, to allow closer observation and earlier medical intervention for those at risk, and to objectively guide prognosis for friends and family of affected individuals. We conducted ...

journal_title：Scientific reports

authors： Gue YX,Tennyson M,Gao J,Ren S,Kanji R,Gorog DA

更新日期：2020-12-07 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Kim KG,Kim SY

更新日期：2019-04-16 00:00:00

abstract：:We present a proposal to realize the quantum Zeno effect (QZE) and quantum Zeno-like effect (QZLE) in a proximal (13)C nuclear spin by controlling a proximal electron spin of a nitrogen vacancy (NV) center. The measurement is performed by applying a microwave pulse to induce the transition between different electronic...

journal_title：Scientific reports

authors： Qiu J,Wang YY,Yin ZQ,Zhang M,Ai Q,Deng FG

更新日期：2015-12-01 00:00:00

abstract：:Although pneumococcal infection is a serious problem worldwide and has a high mortality rate, the molecular mechanisms underlying the lethality caused by pneumococcus remain elusive. Here, we show that BLT2, a G protein-coupled receptor for leukotriene B4 and 12(S)-hydroxyheptadecatrienoic acid (12-HHT), protects mice...

journal_title：Scientific reports

authors： Shigematsu M,Koga T,Ishimori A,Saeki K,Ishii Y,Taketomi Y,Ohba M,Jo-Watanabe A,Okuno T,Harada N,Harayama T,Shindou H,Li JD,Murakami M,Hoka S,Yokomizo T

更新日期：2016-10-05 00:00:00

abstract：:Glacial refugia are centers of high biodiversity. Therefore, knowledge on their locations and reactions of associated populations and landscapes to climatic changes is crucial for conservation management. We here investigated the biogeography of a butterfly species linked to open forest habitats. Using mitochondrial a...

journal_title：Scientific reports

authors： Wendt M,Husemann M,Kramp K,Schmitt T

更新日期：2021-01-08 00:00:00

abstract：:Increased fibroblast growth factor 21 (FGF21) levels have been found in patients with metabolic syndrome (MetS). MetS is also associated with cognitive decline. However, the correlation between FGF21 and cognitive decline in elderly and nonelderly MetS patients has not been investigated. 116 non-elderly patients (age ...

journal_title：Scientific reports

authors： Phrommintikul A,Sa-Nguanmoo P,Sripetchwandee J,Vathesatogkit P,Chattipakorn N,Chattipakorn SC

更新日期：2018-03-26 00:00:00

abstract：:Nitrogen-Vacancy (NV) centers in diamond are promising solid-state quantum emitters that can be utilized for photonic quantum applications. Various diamond nanophotonic devices have been fabricated for efficient extraction of single photons emitted from NV centers to a single guided mode. However, for constructing sca...

journal_title：Scientific reports

authors： Yonezu Y,Wakui K,Furusawa K,Takeoka M,Semba K,Aoki T

更新日期：2017-10-11 00:00:00

abstract：:A physically active lifestyle is associated with better health in body and mind, and it is urgent that supporting agents for such lifestyles be developed. In rodents, voluntary locomotor activity as an active physical behavior may be mediated by dopaminergic neurons (DNs). Thiamine phosphate esters can stimulate DNs, ...

journal_title：Scientific reports

authors： Saiki M,Matsui T,Soya M,Kashibe T,Shima T,Shimizu T,Naruto T,Kitayoshi T,Akimoto K,Ninomiya S,Soya H

更新日期：2018-07-11 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： de Genaro IS,de Almeida FM,Hizume-Kunzler DC,Moriya HT,Silva RA,Cruz JCG,Lopes RB,Righetti RF,de Paula Vieira R,Saiki M,Martins MA,Tibério IFLC,Arantes-Costa FM,Saraiva-Romanholo BM

更新日期：2018-12-12 00:00:00

abstract：:Northern and tropical peatlands represent a globally significant carbon reserve accumulated over thousands of years of waterlogged conditions. It is unclear whether moderate drying predicted for northern peatlands will stimulate burning and carbon losses as has occurred in their smaller tropical counterparts where the...

journal_title：Scientific reports

authors： Kettridge N,Turetsky MR,Sherwood JH,Thompson DK,Miller CA,Benscoter BW,Flannigan MD,Wotton BM,Waddington JM

更新日期：2015-01-27 00:00:00

abstract：:Here we investigated whether endothelial colony forming cells (ECFC) and mesenchymal progenitor cells (MPC) form vascular networks and restore blood flow in ischemic skeletal muscle, and whether host myeloid cells play a role. ECFC + MPC, ECFC alone, MPC alone, or vehicle alone were injected into the hind limb ischemi...

journal_title：Scientific reports

authors： Kang KT,Lin RZ,Kuppermann D,Melero-Martin JM,Bischoff J

更新日期：2017-04-10 00:00:00

abstract：:Contemporary improvements in the type II clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) system offer a convenient way for genome editing in zebrafish. However, the low efficiencies of genome editing and germline transmission require a time-intensive and laborious sc...

journal_title：Scientific reports

authors： Xie SL,Bian WP,Wang C,Junaid M,Zou JX,Pei DS

更新日期：2016-09-29 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transformed hepatocytes may ...

journal_title：Scientific reports

authors： Saito Y,Nakaoka T,Muramatsu T,Ojima H,Sukeda A,Sugiyama Y,Uchida R,Furukawa R,Kitahara A,Sato T,Kanai Y,Saito H

更新日期：2018-02-12 00:00:00

abstract：:Methane concentration in caves is commonly much lower than the external atmosphere, yet the cave CH4 depletion causal mechanism is contested and dynamic links to external diurnal and seasonal temperature cycles unknown. Here, we report a continuous 3-year record of cave methane and other trace gases in Jenolan Caves, ...

journal_title：Scientific reports

authors： Waring CL,Hankin SI,Griffith DWT,Kertesz MA,Kobylski V,Wilson NL,Coleman NV,Kettlewell G,Zlot R,Bosse M,Bell G

更新日期：2017-08-16 00:00:00

abstract：:Alcohol use disorder (AUD) is a chronic and relapsing disease with a substantial genetic influence. Given the recent discovery of the association of PPM1G methylation with alcohol use disorder (AUD) from a genome-wide methylation study, we sought to verify and extend the previous work of AUD-related impulsivity in a K...

journal_title：Scientific reports

authors： Park CI,Kim HW,Hwang SS,Kang JI,Kim SJ

更新日期：2020-03-26 00:00:00

abstract：:H. pylori-induced chronic inflammation is considered the most important cause of gastric cancer. The actual process how chronic inflammation triggers gastric carcinogenesis is still not clear. In this study, neutrophils and relative markers in gastric cancer development were examined with immunohistochemistry and fluo...

journal_title：Scientific reports

authors： Fu H,Ma Y,Yang M,Zhang C,Huang H,Xia Y,Lu L,Jin W,Cui D

更新日期：2016-07-14 00:00:00

abstract：:We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial proteins including uro...

journal_title：Scientific reports

authors： Sugino Y,Nishikawa N,Yoshimura K,Kuno S,Hayashi Y,Yoshimura N,Okazaki T,Kanematsu A,Ogawa O

更新日期：2012-01-01 00:00:00