Consequences of Nosema apis infection for male honey bees and their fertility.

abstract：:The importance of evaluating physical cues in cancer research is gradually being realized. Assessment of cancer cell physical appearance, or phenotype, may provide information on changes in cellular behavior, including migratory or communicative changes. These characteristics are intrinsically different between malign...

journal_title：Scientific reports

authors： Ware MJ,Tinger S,Colbert KL,Corr SJ,Rees P,Koshkina N,Curley S,Summers HD,Godin B

更新日期：2015-07-13 00:00:00

abstract：:Phagocytosis is a required mechanism for the defense against pathogens. Staphylococcus aureus, an important bacterial pathogen, can promptly escape from phagosomes and proliferate within the cytoplasm of host. However, the mechanism of phagocytosis against S. aureus has not been intensively investigated. In this study...

journal_title：Scientific reports

authors： Zhu F,Zhou Y,Jiang C,Zhang X

更新日期：2015-10-07 00:00:00

abstract：:We report, for the first time, the generation of high-order harmonics in a spectral range between 200 eV and 1 keV with an unusual spectral property: only every 4(th) (4i + 1, i∈ℵ) harmonic line appears, whereas the usual high-harmonic spectra consist of every odd (2i + 1) harmonic. We attribute this unique property t...

journal_title：Scientific reports

authors： Seres J,Seres E,Landgraf B,Ecker B,Aurand B,Kuehl T,Spielmann C

更新日期：2014-02-28 00:00:00

abstract：:Autophagy is an essential cellular mechanism that degrades cytoplasmic proteins and organelles to recycle their components; however, the contribution of autophagy during meiosis has not been studied in porcine oocytes maturing in vitro. In this study, we observed that the autophagy-related gene, LC3, was expressed in ...

journal_title：Scientific reports

authors： Shen XH,Jin YX,Liang S,Kwon JW,Zhu JW,Lei L,Kim NH

更新日期：2018-08-22 00:00:00

abstract：:In endometriosis, M2 MΦs are dominant in endometriotic lesions, but the actual role of M2 MΦ is unclear. CD206 positive (+) MΦ is classified in one of M2 type MΦs and are known to produce cytokines and chemokines. In the present study, we used CD206 diphtheria toxin receptor mice, which enable to deplete CD206+ cells ...

journal_title：Scientific reports

authors： Ono Y,Yoshino O,Hiraoka T,Sato E,Furue A,Nawaz A,Hatta H,Fukushi Y,Wada S,Tobe K,Hirota Y,Osuga Y,Unno N,Saito S

更新日期：2021-01-13 00:00:00

abstract：:The quest to 'forward-engineer' and fabricate biological machines remains a grand challenge. Towards this end, we have fabricated locomotive "bio-bots" from hydrogels and cardiomyocytes using a 3D printer. The multi-material bio-bot consisted of a 'biological bimorph' cantilever structure as the actuator to power the ...

journal_title：Scientific reports

authors： Chan V,Park K,Collens MB,Kong H,Saif TA,Bashir R

更新日期：2012-01-01 00:00:00

abstract：:Sorafenib is a RAF inhibitor approved for several cancers, including hepatocellular carcinoma (HCC). Inhibition of RAF kinases can induce a dose-dependent "paradoxical" upregulation of the downstream mitogen-activated protein kinase (MAPK) pathway in cancer cells. It is unknown whether "paradoxical" ERK activation occ...

journal_title：Scientific reports

authors： Chen Y,Liu YC,Sung YC,Ramjiawan RR,Lin TT,Chang CC,Jeng KS,Chang CF,Liu CH,Gao DY,Hsu FF,Duyverman AM,Kitahara S,Huang P,Dima S,Popescu I,Flaherty KT,Zhu AX,Bardeesy N,Jain RK,Benes CH,Duda DG

更新日期：2017-03-09 00:00:00

abstract：:The newly discovered Candidatus 'Methanoperedens nitroreducens' (M. nitroreducens), mediating nitrate-dependent anaerobic oxidation of methane, is an important microorganism in linking carbon and nitrogen cycles. In order to explore the diversity of M. nitroreducens-like archaea in various environmental niches with ad...

journal_title：Scientific reports

authors： Xu S,Cai C,Guo J,Lu W,Yuan Z,Hu S

更新日期：2018-05-16 00:00:00

abstract：:Immune-profiling is becoming an important tool to identify predictive markers for the response to immunotherapy. Our goal was to validate multiplex immunofluorescence (mIF) panels to apply to formalin-fixed and paraffin-embedded tissues using a set of immune marker antibodies, with the Opal™ 7 color Kit (PerkinElmer) ...

journal_title：Scientific reports

authors： Parra ER,Uraoka N,Jiang M,Cook P,Gibbons D,Forget MA,Bernatchez C,Haymaker C,Wistuba II,Rodriguez-Canales J

更新日期：2017-10-17 00:00:00

abstract：:The aim of this study is to determine the prevalence and incidence of ankylosing spondylitis (AS) in South Korea, 2010-2015. This study was conducted using the Health Insurance Review Agency (HIRA) database, which includes information on every patient diagnosed with AS. The incidence and prevalence of AS were evaluate...

journal_title：Scientific reports

authors： Park JS,Hong JY,Park YS,Han K,Suh SW

更新日期：2018-05-16 00:00:00

abstract：:Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs. Compared with short reads, the assemblies obtained from long-read sequencing ...

journal_title：Scientific reports

authors： Giordano F,Aigrain L,Quail MA,Coupland P,Bonfield JK,Davies RM,Tischler G,Jackson DK,Keane TM,Li J,Yue JX,Liti G,Durbin R,Ning Z

更新日期：2017-06-21 00:00:00

abstract：:Cancer dissemination is initiated by the movement of cells into the vasculature which has been reported to be triggered by EMT (epithelial to mesenchymal transition). Cellular dissemination also requires proteases that remodel the extracellular matrix. The protease, plasmin is a prominent player in matrix remodeling a...

journal_title：Scientific reports

authors： Bydoun M,Sterea A,Weaver ICG,Bharadwaj AG,Waisman DM

更新日期：2018-09-20 00:00:00

abstract：:A compact analysis platform for detecting liquid absorption and emission spectra using a set of optical linear variable filters atop a CMOS image sensor is presented. The working spectral range of the analysis platform can be extended without a reduction in spectral resolution by utilizing multiple linear variable fil...

journal_title：Scientific reports

authors： Wan Y,Carlson JA,Kesler BA,Peng W,Su P,Al-Mulla SA,Lim SJ,Smith AM,Dallesasse JM,Cunningham BT

更新日期：2016-07-08 00:00:00

abstract：:Nasoseptal cartilage has been assumed to be isotropic, unlike the well-defined zonal organization of articular cartilage attributed to postnatal biomechanical loading. We know from clinical experience that malrotation of surgical nasoseptal cartilage grafts can lead to increased graft absorption. Other studies have al...

journal_title：Scientific reports

authors： Jessop ZM,Zhang Y,Simoes IN,Al-Sabah A,Badiei N,Gazze SA,Francis L,Whitaker IS

更新日期：2019-08-28 00:00:00

abstract：:Biological armors such as mollusk shells have long been recognized and studied for their values in inspiring novel designs of engineering materials with higher toughness and strength. However, no material is invincible and biological armors also have their rivals. In this paper, our attention is focused on the teeth o...

journal_title：Scientific reports

authors： Fu J,He C,Xia B,Li Y,Feng Q,Yin Q,Shi X,Feng X,Wang H,Yao H

更新日期：2016-03-22 00:00:00

abstract：:In a haptic search task, one has to detect the presence of a target among distractors using the sense of touch. A salient target can be detected faster than a non-salient target. However, little is known about the exploration strategies that are used, especially in 3D search tasks where items are held in the hand. In ...

journal_title：Scientific reports

authors： van Polanen V,Bergmann Tiest WM,Kappers AM

更新日期：2014-09-03 00:00:00

abstract：:Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and Alpha B-crystallin (CRYAB) protein has been identified as a prognostic biomarker for CRC. We evaluated CRYAB C-802G (rs14133)polymorphism in association with CRC risk and survival in Chinese population. We genotyped for CRYAB C-802G (rs14133), ...

journal_title：Scientific reports

authors： Wu X,Zheng YZ,Han B,Wang K

更新日期：2018-08-06 00:00:00

abstract：:Characterisation of G protein-coupled receptors (GPCR) relies on the availability of a toolbox of ligands that selectively modulate different functional states of the receptors. To uncover such molecules, we explored a unique strategy for ligand discovery that takes advantage of the evolutionary conservation of the 60...

journal_title：Scientific reports

authors： Di Giglio MG,Muttenthaler M,Harpsøe K,Liutkeviciute Z,Keov P,Eder T,Rattei T,Arrowsmith S,Wray S,Marek A,Elbert T,Alewood PF,Gloriam DE,Gruber CW

更新日期：2017-02-01 00:00:00

abstract：:Functional dyspepsia (FD) is one of the most prevalent functional gastrointestinal disorders, and more and more multicomponent drugs represented by traditional Chinese medicines have provided a favorable therapeutic effect in its treatment. However, their precise localization in the clinic, as well as corresponding me...

journal_title：Scientific reports

authors： Wei J,Man Q,Guo F,Xian M,Wang T,Tang C,Zhang Y,Li D,Tang D,Yang H,Huang L

更新日期：2019-07-24 00:00:00

abstract：:Plant cells are covered with rigid cell walls, yet tip-growing cells can elongate by providing new cell wall material to their apical regions. Studies of the mechanical properties of tip-growing plant cells typically involve measurement of the turgor pressure and stiffness of the cells' apical regions. These experimen...

journal_title：Scientific reports

authors： Yanagisawa N,Sugimoto N,Arata H,Higashiyama T,Sato Y

更新日期：2017-05-03 00:00:00

abstract：:Groundwater aquifers are an essential source of drinking water, and must be protected against contamination. Phosphogypsum stacks originating from the processing of phosphate rock contain small amounts of radionuclides, such as 226Ra. In September 2016, a sinkhole located beneath a phosphogypsum stack collapsed under ...

journal_title：Scientific reports

authors： Sandhu D,Singh A,Duranceau SJ,Nam BH,Mayo T,Wang D

更新日期：2018-07-30 00:00:00

abstract：:Several MRI contrast agent clinical formulations are now known to leave deposits of the heavy metal gadolinium in the brain, bones, and other organs of patients. This persistent biological accumulation of gadolinium has been recently recognized as a deleterious outcome in patients administered Gd-based contrast agents...

journal_title：Scientific reports

authors： Rees JA,Deblonde GJ,An DD,Ansoborlo C,Gauny SS,Abergel RJ

更新日期：2018-03-13 00:00:00

abstract：:Plant height (PH) is a key factor in maize (Zea mays L.) yield, biomass, and plant architecture. We investigated the PH of diverse maize inbred lines (117 temperate lines, 135 tropical lines) at four growth stages using unmanned aerial vehicle high-throughput phenotypic platforms (UAV-HTPPs). We extracted PH data usin...

journal_title：Scientific reports

authors： Wang X,Zhang R,Song W,Han L,Liu X,Sun X,Luo M,Chen K,Zhang Y,Yang H,Yang G,Zhao Y,Zhao J

更新日期：2019-03-05 00:00:00

abstract：:Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve th...

journal_title：Scientific reports

authors： Mokso R,Schwyn DA,Walker SM,Doube M,Wicklein M,Müller T,Stampanoni M,Taylor GK,Krapp HG

更新日期：2015-03-12 00:00:00

abstract：:This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...

journal_title：Scientific reports

authors： Pontremoli M,Brioschi M,Baetta R,Ghilardi S,Banfi C

更新日期：2018-11-12 00:00:00

abstract：:Surface ocean bubble-bursting generates aerosols composed of microscopic salt-water droplets, enriched in marine organic matter. The organic fraction profoundly influences aerosols' properties, by scattering solar radiations and nucleating water particles. Still little is known on the biochemical and microbiological c...

journal_title：Scientific reports

authors： Rastelli E,Corinaldesi C,Dell'Anno A,Lo Martire M,Greco S,Cristina Facchini M,Rinaldi M,O'Dowd C,Ceburnis D,Danovaro R

更新日期：2017-09-13 00:00:00

abstract：:This study aimed to investigate whether interleukin-34 (IL-34) mRNA expression is aberrant and modulated by tumor necrosis factor-alpha (TNF-α) in knee osteoarthritis (OA) fibroblast-like synoviocytes (FLS) and determine associations of IL-34 mRNA and protein in the systemic and local joint environments with severity ...

journal_title：Scientific reports

authors： Udomsinprasert W,Jinawath A,Teerawattanapong N,Honsawek S

更新日期：2020-05-14 00:00:00

abstract：:Science, being a social enterprise, is subject to fragmentation into groups that focus on specialized areas or topics. Often new advances occur through cross-fertilization of ideas between sub-fields that otherwise have little overlap as they study dissimilar phenomena using different techniques. Thus to explore the n...

journal_title：Scientific reports

authors： Pan RK,Sinha S,Kaski K,Saramäki J

更新日期：2012-01-01 00:00:00

abstract：:Dysregulation of iron metabolism, and resultant cytotoxicity, has been implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative processes. Iron accumulation promotes cytotoxicity through various mechanisms including oxidative stress and glutamate toxicity, and occurs in both MS patients an...

journal_title：Scientific reports

authors： Khan RS,Baumann B,Dine K,Song Y,Dunaief JL,Kim SF,Shindler KS

更新日期：2019-08-12 00:00:00

abstract：:Gold nanoparticles have particular properties distinct from those of bulk gold crystals, and such nanoparticles are used in various applications in optics, catalysis, and drug delivery. Many reports on microbial synthesis of gold nanoparticles have appeared. However, the molecular details (reduction and dispersion) of...

journal_title：Scientific reports

authors： Kikuchi F,Kato Y,Furihata K,Kogure T,Imura Y,Yoshimura E,Suzuki M

更新日期：2016-10-11 00:00:00