Study of the biological function of LncRNA LUCAT1 on cervical cancer cells by targeting miR-199b-5p.

abstract：:Chromosome 14 ORF 166 (C14orf166), a protein involved in the regulation of RNA transcription and translation, has been reported to possess the potency to promote tumorigenesis; however, the role of C14orf166 in non-small-cell lung cancer (NSCLC) remains unknown. The purpose of the present study was to assess C14orf166...

journal_title：Bioscience reports

authors： Zhou YW,Li R,Duan CJ,Gao Y,Cheng YD,Zhang CF

更新日期：2018-09-13 00:00:00

abstract：:Canstatin, the non-collagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. In this study, the inhibitory effect of recombinant canstatin on tumour growth was investigated using a gastric cancer xenograft model. The volume and weight of tumours in mice treated wit...

journal_title：Bioscience reports

authors： Xing YN,Deng P,Xu HM

更新日期：2014-04-01 00:00:00

abstract：:Human endothelial cells from the umbilical vein and skin fibroblasts can be separated by means of centrifugation in a density gradient of Percoll. Cells show a good recovery in culture. Viability is not impaired. ...

journal_title：Bioscience reports

authors： Sbarbati R

更新日期：1985-06-01 00:00:00

abstract：:Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a candidate gene for FSHD. FRG1 regulates various muscle-related functions, but studies have proposed its role in development and angiogenesis also, where it is involved with tumor-associated molecules. Therefore, we decided to look into its role in...

journal_title：Bioscience reports

authors： Tiwari A,Pattnaik N,Mohanty Jaiswal A,Dixit M

更新日期：2017-10-27 00:00:00

abstract：:The emergence of multidrug-resistant (MDR) microbes caused by overuse of antibiotics leads to urgent demands for novel antibiotics exploration. Our recent data showed that Ly2.1-3 (a novel lymphocyte antigen 6 (Ly6) gene cluster) were proteins with cationic nature and rich in cysteine content, that are characteristic ...

journal_title：Bioscience reports

authors： Liu X,Cao X,Wang S,Ji G,Zhang S,Li H

更新日期：2017-01-17 00:00:00

abstract：:Signal transducer and activator of transcription (STAT), a family of latent cytoplasmic transcription factors, are composed of seven identified members (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). STATs are associated with several biological processes such as cell proliferation, invasion, and metastasis in var...

journal_title：Bioscience reports

authors： Li S,Sheng B,Zhao M,Shen Q,Zhu H,Zhu X

更新日期：2017-07-16 00:00:00

abstract：:CXCL8, a member of CXC chemokines, was constitutively expressed in many types of human cancers, and its overexpression has been shown to play a critical role in promoting tumorigenesis. The purpose of the present study was to determine CXCL8 expression in a commercial human liver tissue microarray, and elucidate the e...

journal_title：Bioscience reports

authors： Yang S,Wang H,Qin C,Sun H,Han Y

更新日期：2020-08-28 00:00:00

abstract：:Circulating human neutrophils exhibited low rates of protein biosynthesis, as determined by their ability to incorporate [35S]methionine into TCA-precipitable material. Exposure of cells to the chemotactic peptide (N-formyl-L-methionyl-L-leucyl-L-phenylalanine) increased their rate of protein synthesis, and the maxima...

journal_title：Bioscience reports

authors： Hughes V,Humphreys JM,Edwards SW

更新日期：1987-11-01 00:00:00

abstract：:Imipramine and clorgyline, at concentrations of 0.002 M, inhibit the respiration of brain tissue by 82 and 71 per cent respectively, while chloropromazine and tranylcypromine, at concentrations of 0.01 M, inhibit it about 25 per cent. Deprenyl and amphetamine at a concentration of 0.002 M inhibit brain tissue respirat...

journal_title：Bioscience reports

authors： Nag M,Nandi N

更新日期：1991-02-01 00:00:00

abstract：:Inactivation of p53 is one of the most relevant events in human cancer, since it allows transformed cells to escape their own proliferation control and leave them irresponsive to drugs that aim to damage their DNA. When p53 falls, other members of its family may become targets to attack tumoural cells. p73 has shown c...

journal_title：Bioscience reports

authors： Sánchez-Carrera D,García-Puga M,Yáñez L,Romón Í,Pipaón C

更新日期：2015-04-28 00:00:00

abstract：:Abnormal aggregation of pathological tau protein is a neuropathological feature of Alzheimer's disease (AD). In the AD patients, the abnormal tau accumulation first appeared in entorhinal cortex (EC) and then propagated to the hippocampus with microglia activation and inflammation, but the mechanism is elusive. Here, ...

journal_title：Bioscience reports

authors： Liu Y,Zhang S,Li X,Liu E,Wang X,Zhou Q,Ye J,Wang JZ

更新日期：2020-02-28 00:00:00

abstract：:Ehrlich Ascites Tumour cells were irradiated with UV-light to crosslink DNA to proteins in vivo. The DNA fragments associated with the nuclear lamina were purified and characterized. The results of the Cot analysis and the hybridization experiments suggest that the DNA fragments attached to the nuclear lamina although...

journal_title：Bioscience reports

authors： Christova R,Yaneva J,Galcheva-Gargova Z

更新日期：1989-10-01 00:00:00

abstract：:Mouse Mex3c encodes RNA-binding proteins of variant length through alternative splicing. Its mutation results in multiple defects including growth retardation, perturbed energy balance, and defective antiviral innate immunity. Here we report that Mex3c mutation affects mammary gland development and lactation in female...

journal_title：Bioscience reports

authors： Du Y,Sun D,Li Y

更新日期：2020-12-23 00:00:00

abstract：:Peanut (Arachis hypogaea) seed lectin, PNA is widely used to identify tumor specific antigen (T-antigen), Galbeta1-3GalNAc on the eukaryotic cell surface. The functional amino acid coding region of a cDNA clone, pBSH-PN was PCR amplified and cloned downstream of the polyhedrin promoter in the Autographa californica nu...

journal_title：Bioscience reports

authors： Kumar M,Behera AK,Kumar S,Srinivas VR,Das HR,Surolia A,Das RH

更新日期：1999-06-01 00:00:00

abstract：:Interleukin-21 (IL-21) is a cytokine that plays a crucial role in pathogenesis and activity of the rheumatoid arthritis (RA). Meanwhile, genetic polymorphisms in the IL-21 gene may alter its expression. Previous studies have reported conflicting results assessing the association between the IL-21 rs6822844 G/T polymor...

journal_title：Bioscience reports

authors： Yu M,Hou J,Zheng M,Cao Y,Alike Y,Mi Y,Zhu J

更新日期：2020-01-31 00:00:00

abstract：:In plants, the hydroxymethylpyrimidine (HMP) and thiazole precursors of thiamin are synthesized and coupled together to form thiamin in plastids. Mutants unable to form HMP can be rescued by exogenous HMP, implying the presence of HMP transporters in the plasma membrane and plastids. Analysis of bacterial genomes reve...

journal_title：Bioscience reports

authors： Beaudoin GAW,Johnson TS,Hanson AD

更新日期：2018-03-29 00:00:00

abstract：:Three myoid-cell clones were established from the thymuses of two Wistar rats; one thymus yielded two clones, R615A and R615B2, and the other yielded one clone, R613Ad. The three clones were divided into two subtypes. Both subtypes were able to form myofibrils, expressed AChR on their cell-surface membrane, and contai...

journal_title：Bioscience reports

authors： Kamo I,Nonaka I,Furukawa S,Satoyoshi E

更新日期：1984-11-01 00:00:00

abstract：:High-affinity binding of 3H-folate in Triton X-100 solubilized membranes of human liver displayed characteristics, e.g. apparent positive cooperativity, which are typical of specific folate binding. Ultrogel AcA 44 chromatography of solubilized membranes saturated with 3H-folate revealed a major peak of 100 kDa and a ...

journal_title：Bioscience reports

authors： Holm J,Hansen SI,Høier-Madsen M

更新日期：1991-06-01 00:00:00

abstract：:Calmodulin-free ghost membranes were prepared from erythrocytes of kwashiorkor children and from healthy children in the same age bracket. In the absence of calmodulin, the specific activity of Mg2+-dependent Ca2+-pumping ATPase (Ca2+ + Mg2+-ATPase) of kwashiorkor membranes was more than 40 percent lower than the spec...

journal_title：Bioscience reports

authors： Olorunsogo OO

更新日期：1989-06-01 00:00:00

abstract：:Although membrane fusion occurs ubiquitously and continuously in all eukaroytic cells, little is known about the mechanism that governs lipid bilayer fusion associated with any intracellular fusion reactions. Recent studies of the fusion of enveloped viruses with host cell membranes have helped to define the fusion pr...

journal_title：Bioscience reports

authors： Martin I,Ruysschaert JM

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:MicroRNA-135 (miR-135) is a well-known non-coding RNA that has been demonstrated to participate in tumorigenesis and cancer development; however, the clinical prognostic value of miR-135 in digestive system cancers remains controversial. This meta-analysis aims to explore the potential value of miR-135 as a ...

journal_title：Bioscience reports

authors： Chao C,Sang C,Wang M,Wang Z,Li Y,Luo G,Zhang X

更新日期：2019-12-20 00:00:00

abstract：:Mitochondria are known to participate in the initiation of programmed cell death (PCD) in animals and in plants. The role of chloroplasts in PCD is still unknown. We describe a new system to study PCD in plants; namely, leaf epidermal peels. The peel represents a monolayer consisting of cells of two types: phototrophi...

journal_title：Bioscience reports

authors： Samuilov VD,Lagunova EM,Kiselevsky DB,Dzyubinskaya EV,Makarova YV,Gusev MV

更新日期：2003-04-01 00:00:00

abstract：:More than 60 million people in the world have been diagnosed with HIV infections since the virus was recognized as the causative agent of AIDS in the 1980s. Even though more than half of the infected patients have died, effective disease treatment and prevention measures have not been established. ART (antiretroviral ...

journal_title：Bioscience reports

authors： Choi J,Jeong Y,Han HS,Lee KH

更新日期：2014-08-18 00:00:00

abstract：:Matrix-bound monoclonal antibodies against urokinase have been used to purify this enzyme by affinity chromatography. In a single-step procedure, urokinase can be isolated from crude preparations with high yield and high purity, and without loss of enzymatic activity. ...

journal_title：Bioscience reports

authors： Hérion P,Bollen A

更新日期：1983-04-01 00:00:00

abstract：:Whether they are small enough to wriggle through the current-carrying part of an ionic channel or big enough to be kept outside and thus able to exert an osmotic stress on the channel space, polymers interact with channels in several instructive ways. The osmotic stress of excluded polymers allows one to measure the n...

journal_title：Bioscience reports

authors： Parsegian VA,Bezrukov SM,Vodyanoy I

更新日期：1995-12-01 00:00:00

abstract：:The concentration of Na+ and K+ and the pH in the cytoplasm of Lettré cells was measured by monitoring the net flux of H+, Na+, or K+ across the plasma membrane which had been rendered permeable to these ions by the action of Sendai virus. Ion flux was measured directly by analysis of cell composition, or indirectly b...

journal_title：Bioscience reports

authors： Bashford CL,Alder G,Micklem KJ,Pasternak CA

更新日期：1983-07-01 00:00:00

abstract：:Emerging evidence are accumulating that long noncoding RNAs (lncRNAs) have recently been identified to participate in various cellular processes. Terminal differentiation induced ncRNA (TINCR) is a newly identified lncRNA with its functional roles not fully elucidated in human malignancy. The current study aims to ide...

journal_title：Bioscience reports

authors： Tian F,Xu J,Xue F,Guan E,Xu X

更新日期：2017-07-27 00:00:00

abstract：:The effect that research on dopamine and other neutro trasmitters has on disciplines like neurology and psychiatry is described. ...

journal_title：Bioscience reports

authors： Carlsson A

更新日期：2001-12-01 00:00:00

abstract：:Huaier Granule, a type of traditional Chinese biomedical preparation (TCBP), is considered to be a promising adjuvant therapy for breast cancer. Although an analysis of the published literature has been performed, the exact effects and safety of Huaier Granule remains controversial. Therefore, a wide-ranging systemati...

journal_title：Bioscience reports

authors： Yao X,Wu W,Qu K,Xi W

更新日期：2020-08-28 00:00:00

abstract：:In the present study, we aimed to examine whether SET domain-containing methyltransferases are up-regulated in different classes of renal cell carcinoma. We immunoblotted against SET domain and quantified the expression of these modular domains. Furthermore, we examined the expression of Rad51, the key protein that co...

journal_title：Bioscience reports

authors： Liu S,Li Y,Xu H,Wang K,Li N,Li J,Sun T,Xu Y

更新日期：2016-06-30 00:00:00