Abstract:
PURPOSE:To compare the efficacy and visual outcomes after femtosecond laser small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in correcting high myopia. METHODS:This prospective, randomized study included patients who underwent SMILE or FS-LASIK for the correction of high myopia [the sum of spherical and cylindrical error from -10.00 to -14.00 dioptres (D)]. Preoperative, 1-month (P1m), 3-months (P3m) and 6-months (P6m) postoperative outcomes were analysed and compared between the two procedures. RESULTS:Ninety-six right eyes of 96 patients (SMILE: n = 51, FS-LASIK: n = 45) were included. Both the (Attempted - achieved) sphere and the (attempted - achieved) spherical equivalent (SEQ) were greater in the FS-LASIK group at all three postoperative time-points (p < 0.001). The postoperative vector means of astigmatism were smaller in the SMILE group than in the FS-LASIK group. The differences between the optical zone of tissue removal (ROZ) during surgery and the postoperative functional optical zone (FOZ; ROZ-FOZ) were smaller in the SMILE group than in the FS-LASIK group. No significant difference was found between the two procedures in the delta-root mean square (RMS) of aberrations, except for delta-spherical aberration (SA) at P3m. CONCLUSIONS:Both SMILE and FS-LASIK are effective in correcting high myopia. SMILE resulted in less under-correction, less regression, a smaller decrease in the FOZ and a smaller increase in SA when compared to FS-LASIK, resulting in better visual outcomes with SMILE.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Qian Y,Chen X,Naidu RK,Zhou Xdoi
10.1111/aos.14078subject
Has Abstractpub_date
2020-03-01 00:00:00pages
e161-e172issue
2eissn
1755-375Xissn
1755-3768journal_volume
98pub_type
杂志文章,随机对照试验abstract:PURPOSE:To evaluate the effect of photodynamic therapy (PDT) on central serous chorioretinopathy (CSC) compared with laser therapy and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs, and to find the maximum treatment effect with minimal dose and fluence of PDT. METHODS:A systematic...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/aos.12482
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To determine whether decreasing illumination of the Pelli-Robson contrast sensitivity (CS) chart and MP-1 microperimeter to low mesopic conditions is more sensitive to vision changes occurring with healthy ageing and in early and intermediate age-related macular degeneration (AMD) and whether these mesopic test...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13112
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Galectin-1 regulates endothelial cell function and promotes angiogenesis. We investigated the hypothesis that galectin-1 may be involved in the pathogenesis of proliferative diabetic retinopathy (PDR). METHODS:Vitreous samples from 36 PDR and 20 nondiabetic patients, epiretinal fibrovascular membranes from 13 ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14191
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To describe three cases of Charles Bonnet syndrome (CBS) in glaucoma patients with preserved visual acuity. METHODS:Three glaucoma patients who had taken part in a recent CBS study were interviewed about their hallucinations. The patients underwent macular optical coherence tomography (OCT) of both eyes. The v...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14620
更新日期:2020-09-11 00:00:00
abstract:AIMS:This prospective, multicenter, single-masked study evaluated the additive effect of dorzolamide hydrochloride 2% on the diurnal intraocular pressure (IOP) curve and retinal and retrobulbar hemodynamics in patients with primary open-angle glaucoma (POAG) treated with morning-dosed bimatoprost 0.03%. METHODS:Eighty...
journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1755-3768.2010.02036.x
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13047
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Posterior capsule opacification (PCO) occurs as a common complication after cataract surgery. Erlotinib is an inhibitor of the epidermal growth factor-Receptor and reduces critical cellular events leading to PCO. In this in vitro study, Erlotinib-modified intraocular lenses (IOLs) employed as a drug delivery de...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13759
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:The introduction of vascular endothelial growth factor inhibitors for the treatment of exudative age-related macular degeneration (AMD) has increased the referral rates of AMD patients with visual symptoms to treating centres considerably. However, a large proportion of the referred patients do not qualify for ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.02074.x
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To investigate the feasibility, effectiveness and acceptability of using prosthetic occluding contact lenses (OCLs) to treat moderate amblyopia in adults and of the role of the multifocal visual evoked potential (mfVEP) as a predictor of postamblyopic therapy. METHODS:A comparative, prospective, interventional...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.13585
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the safety and efficacy of phacocanaloplasty with suprachoroidal drainage (PCscD) and to compare its intraocular pressure (IOP)-lowering and drug-sparing effect to canaloplasty with suprachoroidal drainage (CscD). METHODS:The study retrospective interventional study...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13393
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To assess the effect of donor tissue diameter in Descemet Membrane Endothelial Keratoplasty (DMEK) on postoperative endothelial cell density (ECD) mainly in Fuchs Endothelial Corneal Dystrophy (FECD) patients. METHODS:Retrospective review of 693 consecutive DMEK surgeries from the prospective Cologne DMEK data...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13943
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children. SETTING:Ege University Faculty of Medicine, Department of Ophthalmology. METHODS:Pentacam measurements of 50 (23 boys and 27 girls) children...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02122.x
更新日期:2011-08-01 00:00:00
abstract::Working at the nanoscale means to completely rethink how to approach engineering in the body in general and in the eye in particular. In nanomedicine, tissue engineering is the ability to influence an environment either by adding, subtracting or manipulating that environment to allow it to be more conducive for its pu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2010.01982.x
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To compare changes in macular pigment optical density (MPOD) and serum lutein concentration between free lutein and lutein esters supplements in healthy Japanese individuals. METHODS:Twenty healthy subjects (age range, 22-47 years) were recruited into this prospective, randomized, doubled-blind comparative stu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.13106
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To compare structural and functional improvements in patients with vitreous haemorrhage (VH) with different IOPs re-established at the end of pars plana vitrectomy (PPV). METHODS:It is a prospective, randomized, comparative, interventional study. Ninety-five patients with nonclearing VH were randomized to rece...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14293
更新日期:2020-06-01 00:00:00
abstract::A growing number of studies have reported a link between vascular damage and glaucoma based on optical coherence tomography angiography (OCTA) imaging. This multitude of studies focused on different regions of interest (ROIs) which offers the possibility to draw conclusions on the most discriminative locations to diag...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.14392
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS:Cross-sectional stu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13956
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To investigate the clinical features and outcomes of diffuse large B-cell lymphoma (DLBCL) involving the eye and ocular adnexa in an East Asian population and emphasize the importance of prompt biopsy and treatment in unusually progressive ocular adnexal DLBCL for better visual outcomes. METHODS:Retrospective ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14725
更新日期:2021-01-09 00:00:00
abstract:PURPOSE:To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. METHODS:This was a prospective, observati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12382
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To describe the concordance of keratoconus in 18 sets of twins. METHODS:Thirteen monozygotic (MZ) and five dizygotic (DZ) pairs of twins were identified during an investigation of familial keratoconus. We used 16 forensic microsatellite markers to confirm the zygosity of same sex twins. Patients and available ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02448.x
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01997.x
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:As some surgical procedures have been shown to increase postoperative flare values and thus contribute to blood-ocular barrier breakdown, retinal reattachment surgery might influence the risk of developing proliferative vitreoretinopathy (PVR). Therefore, we investigated whether postoperative aqueous flare valu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13560
更新日期:2018-03-01 00:00:00
abstract::In the time of Vesalius, knowledge of ocular anatomy was limited. The first description of the anatomy of the eye comes from Democrites, for whom the eye was surrounded by two 'coats', filled with a homogenous fluid. The optic nerve was hollow and the lens was considered to be a postmortem artefact. Until the 15th cen...
journal_title:Acta ophthalmologica
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1755-3768.2009.01679.x
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To assess the trend patterns and gender disparity in global burden of vision loss due to diabetic retinopathy (DR) by year, age, region and socioeconomic status using prevalence and years lived with disability (YLDs) from Global Burden of Disease (GBD) study 2017. METHODS:Prevalence and YLDs data of vision los...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14644
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14333
更新日期:2019-12-29 00:00:00
abstract:PURPOSE:To investigate and analyse one hundred-year-old endothelial cells of human transplanted corneal grafts and compare them with intact endothelium of unoperated eyes. SUBJECTS AND METHODS:Specular microscopy was performed on seven individuals (14 eyes) aged >100 years and on seven transplanted corneas with endoth...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12715
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:A recent threefold increase in laser treatment for advanced retinopathy of prematurity (ROP) triggered a nationwide preschool ophthalmic and developmental status among extremely preterm survivors. Here, we discuss refraction and visual acuity. METHODS:Survivors (n = 178) from a national birth cohort (February ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12643
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To study the connection between parental myopia and their children's myopia from school age to adulthood. METHODS:Two hundred and forty myopic schoolchildren (119 boys, 121 girls, mean age 10.9 years) with no previous spectacles for myopia were recruited to a 3-year treatment trial with different use of specta...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.13043
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Previous studies have indicated that the immune system is involved in the pathogenesis of the AMD. Increased visceral fat, in addition, has a pro-inflammatory effect on the organism by producing or influencing different kinds of inflammatory factors. The aim of this study is to determine the relationship of bod...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12670
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Life expectancy is increasing. When corneal donors become older and corneal-grafted patients live longer with their graft, the need for good-quality donor tissue becomes more crucial. The aim of the present investigation is to study grafted recipients with a donor cornea with a total tissue age of more than 100...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12231
更新日期:2014-08-01 00:00:00