The eye of Vesalius.

abstract：PURPOSE:To examine the public health impact of presbyopia regarding its effect on quality of life (QoL) and society in both the developed and developing worlds. METHODS:A database was created from articles found on PubMed, the Cochrane Library and Science Direct using the following search terms: presbyopia, QoL, accom...

journal_title：Acta ophthalmologica

authors： Goertz AD,Stewart WC,Burns WR,Stewart JA,Nelson LA

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Using OCT-A to investigate the association between neurodegeneration and vascular morphology in diabetic retinopathy (DR). METHODS:Cross-sectional study. One hundred and sixty-two patients were enrolled and following fundoscopy were assigned to two groups according to DR severity: 54 patients to the group of n...

journal_title：Acta ophthalmologica

authors： Bontzos G,Kabanarou SA,Gkizis I,Ragkousis A,Xirou T,Peto T

更新日期：2021-01-10 00:00:00

abstract：:Our review aims to provide an update of management protocols for congenital nasolacrimal duct obstruction (CNDO). Although early probing performed before the age of 1 year was traditionally recommended, many reports have since confirmed high frequencies of spontaneous resolution during the first year of life. Accordin...

journal_title：Acta ophthalmologica

authors： Takahashi Y,Kakizaki H,Chan WO,Selva D

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT). METHODS:A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular press...

journal_title：Acta ophthalmologica

authors： Ilveskoski L,Taipale C,Tuuminen R

更新日期：2020-02-01 00:00:00

abstract：:Corneal refractive surgery disrupts corneal integrity and reduces biomechanical stability in consequence of the beneficial refractive alteration. The minimal invasive cap-based refractive procedure, small-incision lenticule extraction (SMILE), has been proposed to affect corneal integrity less than flap-based procedur...

journal_title：Acta ophthalmologica

authors： Raevdal P,Grauslund J,Vestergaard AH

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To describe the clinical phenotype and the molecular pathology in a group of patients with congenital stationary night blindness due to mutations in GRM6, a gene encoding the ON bipolar metabotropic glutamate receptor 6 (mGluR6). METHODS:Nine patients from seven families (age range, 7-75; median, 10 years) wit...

journal_title：Acta ophthalmologica

authors： Sergouniotis PI,Robson AG,Li Z,Devery S,Holder GE,Moore AT,Webster AR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To evaluate the effect of intravitreal injections of triamcinolone acetonide (IVTA) combined with panretinal photocoagulation (PRP) on visual acuity (VA) and foveal thickness in patients with concomitant high-risk proliferative diabetic retinopathy (PDR) and clinically significant macular oedema (CSMO). METHOD...

journal_title：Acta ophthalmologica

authors： Margolis R,Singh RP,Bhatnagar P,Kaiser PK

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643). METHODS:Twenty-four rabbits ...

journal_title：Acta ophthalmologica

authors： Schultheiss M,Schnichels S,Konrad EM,Bartz-Schmidt KU,Zahn G,Caldirola P,Fsadni MG,Caram-Lelham N,Spitzer MS

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To examine the prevalence of anisometropia of spherical refraction (AnisoSR), astigmatism (AnisoAST) and spherical equivalent (AnisoSE) and their associations with spherical refraction (SR), refractive astigmatism (AST), spherical equivalent (SE) and interocular differences of ocular biometric parameters among ...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M,Kaprio J,Rantanen T

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:Orally administered angiotensin II receptor blockers (ARBs) decrease intraocular pressure (IOP). Topical administration may reduce systemic side effects and result in a useful glaucoma drug. The aim of this study is to test the ocular delivery and pharmacologic effect of nanoparticle eye drops containing ARBs (...

journal_title：Acta ophthalmologica

authors： Lorenzo-Soler L,Olafsdottir OB,Garhöfer G,Jansook P,Kristinsdottir IM,Tan A,Loftsson T,Stefansson E

更新日期：2020-11-16 00:00:00

abstract：PURPOSE:To investigate whether exposure to antazoline-naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans. METHODS:All women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at le...

journal_title：Acta ophthalmologica

authors： Thomseth V,Cejvanovic V,Jimenez-Solem E,Poulsen HE,Utheim TP,Andersen JT

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To examine the patient's subjective visual sensations during cataract surgery performed under topical anaesthesia. METHODS:Prospective, non-randomized, cohort study. One hundred and thirty-two patients were interviewed by standard questionnaire within 1 hr of uncomplicated cataract surgery performed under topi...

journal_title：Acta ophthalmologica

authors： Biró Z,Schvöller M

更新日期：2008-12-01 00:00:00

abstract：:Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

journal_title：Acta ophthalmologica

authors： Hajari JN

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of big-bubble (BB) technique in separating Dua's layer together with the Descemet's membrane endothelial (DE) graft and the effect of 7-day storage of the prepared tissues on the endothelial cells. METHOD:This is an experimental study in which 21 human corneo-scleral tissues unsuitable...

journal_title：Acta ophthalmologica

authors： GamalElDin SA,Salama MM,ElShazly MI

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS:Data from 139 patients with conjunctival mela...

journal_title：Acta ophthalmologica

authors： Larsen AC,Dahl C,Dahmcke CM,Lade-Keller J,Siersma VD,Toft PB,Coupland SE,Prause JU,Guldberg P,Heegaard S

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To determine whether the hill of vision for Short-Wavelength Automated Perimetry (SWAP) is shallower for women who consume phyto-oestrogen-rich foods than for women who do not. METHODS:Visual field data were compared for two groups of healthy amenorrhoeic women 48-69 years-old with normal vision and not using ...

journal_title：Acta ophthalmologica

authors： Eisner A,Demirel S

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To assess the association between exogenous oestrogen exposure, female reproductive factors and the long-term incidence of cataract. METHODS:People aged 49+ years living in a defined geographic region were invited to participate in this prospective population-based survey. Of 2072 women (83% of those eligible)...

journal_title：Acta ophthalmologica

authors： Kanthan GL,Wang JJ,Burlutsky G,Rochtchina E,Cumming RG,Mitchell P

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To indirectly measure stromal riboflavin penetration using commercially available riboflavin solutions and new and existing epithelium-off, trans-epithelial and iontophoresis-assisted delivery protocols. METHODS:Forty porcine eyes were divided into eight groups. Group 1: Ricrolin applied to the de-epithelialis...

journal_title：Acta ophthalmologica

authors： Hayes S,Morgan SR,O'Brart DP,O'Brart N,Meek KM

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To report the accuracy of intraocular lens (IOL) power estimation in eyes that have undergone phacovitrectomy for retinal diseases with accompanying macular oedema. METHODS:A retrospective study was conducted in 23 eyes of 23 patients at Soonchunhyang University Hospital, Seoul, Korea. The relationship between...

journal_title：Acta ophthalmologica

authors： Sun HJ,Choi KS

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:The cyclolignan picropodophyllin (PPP) efficiently blocks the activity of insulin-like growth factor-1 receptor (IGF-1R) and inhibits growth of uveal melanoma cells in vitro and in vivo. In this study, we aimed to investigate the efficiency of orally administered PPP on growth of uveal melanoma xenografts. Furt...

journal_title：Acta ophthalmologica

authors： Economou MA,Andersson S,Vasilcanu D,All-Ericsson C,Menu E,Girnita A,Girnita L,Axelson M,Seregard S,Larsson O

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To analyse the anterior lens capsule thickness and ultrastructure changes of intumescent white cataracts in comparison with nuclear cataracts to prove possible structural reasons for surgical difficulties with the intumescent white cataract. METHODS:Anterior lens capsules from 35 eyes with intumescent white an...

journal_title：Acta ophthalmologica

authors： Hawlina M,Stunf S,Hvala A

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...

journal_title：Acta ophthalmologica

authors： Prokosch V,Brockhaus K,Anders F,Liu H,Mercieca K,Gericke A,Melkonyan H,Thanos S

更新日期：2019-12-29 00:00:00

abstract：PURPOSE:Complex segregation analysis of 60 unrelated sporadic keratoconus (KC) families was performed to reveal the presumed mode of inheritance in our dataset. METHODS:Sixty probands, 212 family members and 212 age and gender matched healthy controls underwent clinical and videokeratographic examination. Family aggre...

journal_title：Acta ophthalmologica

authors： Kriszt A,Losonczy G,Berta A,Vereb G,Takács L

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To determine (i) whether, compared to controls, visual complaints of glaucoma patients are more pronounced under extreme luminance conditions than in the optimal luminance condition and (ii) whether complaints belonging to different extreme luminance conditions are associated. METHODS:We developed a luminance-...

journal_title：Acta ophthalmologica

authors： Bierings RAJM,van Sonderen FLP,Jansonius NM

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...

journal_title：Acta ophthalmologica

authors： Loukovaara S,Haukka J

更新日期：2021-01-02 00:00:00

abstract：PURPOSE:As some surgical procedures have been shown to increase postoperative flare values and thus contribute to blood-ocular barrier breakdown, retinal reattachment surgery might influence the risk of developing proliferative vitreoretinopathy (PVR). Therefore, we investigated whether postoperative aqueous flare valu...

journal_title：Acta ophthalmologica

authors： Mulder VC,van Dijk EHC,van Meurs IA,La Heij EC,van Meurs JC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the prognosis of mortality in patients with spontaneous subarachnoid haemorrhage associated with Terson's syndrome. METHODS:A prospective, consecutive case series study was conducted in patients admitted to the emergency room with a diagnosis of acute subarachnoid haemorrhage. After a complete neur...

journal_title：Acta ophthalmologica

authors： Sung W,Arnaldo B,Sergio C,Juliana S,Michel F

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To investigate the presence and distribution of l-kynurenine aminotransferases immunoreactivity in human and animal lenses during cataract formation. METHODS:Immunohistochemistry was conducted using polyclonal antibodies against KAT I, KAT II and KAT III on sections of 26 anterior capsules from patients underg...

journal_title：Acta ophthalmologica

authors： Rejdak R,Oleszczuk A,Rummelt C,Turski WA,Choragiewicz T,Nowomiejska K,Ksiazek K,Thaler S,Zarnowski T,Okuno E,Grieb P,Zrenner E,Kruse F,Junemann AG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To develop an objective intraocular inflammation composite score. METHODS:Cross-sectional study. Non-invasive image acquisition and processing were conducted from April 2017 to April 2019. Inflammation-grade stratified eyes from patients with active, inactive uveitis and healthy controls were recruited. After ...

journal_title：Acta ophthalmologica

authors： Llorenç V,Serrano AR,Mesquida M,Lin P,Esquinas C,Sainz-de-la-Maza M,Metea C,Bosch A,Calvo M,Balter A,Nakamura Y,Molins B,Alba C,Suhler E,Adán A

更新日期：2021-01-09 00:00:00