Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.

abstract：:Our review aims to provide an update of management protocols for congenital nasolacrimal duct obstruction (CNDO). Although early probing performed before the age of 1 year was traditionally recommended, many reports have since confirmed high frequencies of spontaneous resolution during the first year of life. Accordin...

journal_title：Acta ophthalmologica

authors： Takahashi Y,Kakizaki H,Chan WO,Selva D

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To compare pars plana vitrectomy and 360° endolaser therapy with pars plana vitrectomy and an encircling scleral buckle for the treatment of primary rhegmatogenous retinal detachments in a randomized pilot study including 60 patients. METHODS:Main outcome measures were single-surgery anatomic success rate and ...

journal_title：Acta ophthalmologica

authors： Falkner-Radler CI,Graf A,Binder S

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to analyse 69 Chinese patients with USH2A mutations and to assess the genotype-phenotype correlation. METHODS:All 36 Usher syndrome type IIA patients and 33 nonsyndromic RP (retinitis pigmentosa) patients underwent clinical examinations. Eye examinations included best-corrected visual...

journal_title：Acta ophthalmologica

authors： Meng X,Liu X,Li Y,Guo T,Yang L

更新日期：2020-10-29 00:00:00

abstract：PURPOSE:This study aimed to investigate intraocular pressure (IOP) measurements taken using the dynamic contour tonometer (DCT) and the non-contact tonometer (NCT) in subjects with keratoconus. METHODS:Intraocular pressure was measured in 20 keratoconus subjects and 20 age-matched control subjects using the DCT and NC...

journal_title：Acta ophthalmologica

authors： Read SA,Collins MJ

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To examine the prevalence of anisometropia of spherical refraction (AnisoSR), astigmatism (AnisoAST) and spherical equivalent (AnisoSE) and their associations with spherical refraction (SR), refractive astigmatism (AST), spherical equivalent (SE) and interocular differences of ocular biometric parameters among ...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M,Kaprio J,Rantanen T

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To investigate risk factors for the development of the hypertensive phase after implantation of the Ahmed glaucoma valve (AGV). METHODS:A total of 128 patients who had undergone AGV implantation were included in this study. The hypertensive phase was defined as intraocular pressure (IOP) > 21 mmHg during the f...

journal_title：Acta ophthalmologica

authors： Jung KI,Park CK

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To report the functional and anatomical outcomes resulting from the use of intravitreal pegaptanib sodium (Macugen) in patients with diabetic macular oedema (DMO). METHODS:We conducted a retrospective outcome analysis, by optical coherence tomography (OCT) and best-corrected visual acuity (BCVA), of eyes with ...

journal_title：Acta ophthalmologica

authors： Querques G,Bux AV,Martinelli D,Iaculli C,Noci ND

更新日期：2009-09-01 00:00:00

abstract：:Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

journal_title：Acta ophthalmologica

authors： Hajari JN

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To study the connection between parental myopia and their children's myopia from school age to adulthood. METHODS:Two hundred and forty myopic schoolchildren (119 boys, 121 girls, mean age 10.9 years) with no previous spectacles for myopia were recruited to a 3-year treatment trial with different use of specta...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To investigate the feasibility, effectiveness and acceptability of using prosthetic occluding contact lenses (OCLs) to treat moderate amblyopia in adults and of the role of the multifocal visual evoked potential (mfVEP) as a predictor of postamblyopic therapy. METHODS:A comparative, prospective, interventional...

journal_title：Acta ophthalmologica

authors： Garcia-Romo E,Perez-Rico C,Roldán-Díaz I,Arévalo-Serrano J,Blanco R

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children. SETTING:Ege University Faculty of Medicine, Department of Ophthalmology. METHODS:Pentacam measurements of 50 (23 boys and 27 girls) children...

journal_title：Acta ophthalmologica

authors： Palamar M,Egrilmez S,Uretmen O,Yagci A,Kose S

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT). METHODS:A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular press...

journal_title：Acta ophthalmologica

authors： Ilveskoski L,Taipale C,Tuuminen R

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:We aimed to determine prospectively the incidence of abnormal test results on frequency doubling perimetry (FDT), the nerve fibre analyser (GDx) and standard automated perimetry (SAP) in a cohort of glaucoma suspect patients with normal findings for all these tests at baseline. METHODS:Seventy glaucoma suspect...

journal_title：Acta ophthalmologica

authors： Jansonius NM,Heeg GP

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:Lacrimal gland tumours constitute a wide spectrum of neoplastic lesions that are histologically similar to tumours of the salivary gland. In the salivary gland, pleomorphic adenoma (PA) is frequently characterized by recurrent chromosomal rearrangements of the PLAG1 and HMGA2 genes, a genetic feature retained i...

journal_title：Acta ophthalmologica

authors： Andreasen S,von Holstein SL,Homøe P,Heegaard S

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To investigate and analyse one hundred-year-old endothelial cells of human transplanted corneal grafts and compare them with intact endothelium of unoperated eyes. SUBJECTS AND METHODS:Specular microscopy was performed on seven individuals (14 eyes) aged >100 years and on seven transplanted corneas with endoth...

journal_title：Acta ophthalmologica

authors： Ruusuvaara P,Vesti E,Koskela E,Setälä K

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Current fundus imaging in newborn babies requires mydriatics, eye specula and corneal contact. We propose that a scanning laser ophthalmoscope (SLO) allows ultra wide-field imaging with reduced stress for the child. METHODS:This prospective observational single centre study was conducted in Landspítali, Univer...

journal_title：Acta ophthalmologica

authors： Magnusdottir V,Vehmeijer WB,Eliasdottir TS,Hardarson SH,Schalij-Delfos NE,Stefánsson E

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To study the effect of glaucoma drainage implant (GDI) surgery on corneal topography during the first postoperative year. METHODS:Twenty-one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 GDI. Corneal topography measurements were taken preoperatively and at 6 and 12 months after surg...

journal_title：Acta ophthalmologica

authors： Koivusalo R,Välimäki J

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:Orally administered angiotensin II receptor blockers (ARBs) decrease intraocular pressure (IOP). Topical administration may reduce systemic side effects and result in a useful glaucoma drug. The aim of this study is to test the ocular delivery and pharmacologic effect of nanoparticle eye drops containing ARBs (...

journal_title：Acta ophthalmologica

authors： Lorenzo-Soler L,Olafsdottir OB,Garhöfer G,Jansook P,Kristinsdottir IM,Tan A,Loftsson T,Stefansson E

更新日期：2020-11-16 00:00:00

abstract：PURPOSE:To investigate the incidence and cause of severe visual loss following use and removal of intraocular silicone oil (SiO) after uncomplicated vitrectomy and SiO injection for primary rhegmatogenous retinal detachment (RRD). METHODS:Consecutive case series of 216 patients operated with vitrectomy for primary RRD...

journal_title：Acta ophthalmologica

authors： Christensen UC,la Cour M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To describe the different clinical presentations of periocular molluscum contagiosum (MC) lesions and their epidemiological, clinical and histopathological features. METHODS:Medical records and histopathological sections of all cases of periocular MC treated at the oculoplastic clinic of the Goldschleger Eye I...

journal_title：Acta ophthalmologica

authors： Rosner M,Zloto O

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:Limited knowledge exists about the influence of donor age and death-to-preservation interval (DPI) on the metabolic properties of the cornea. The aim of this study is to investigate the relationship between both factors and metabolite content of the cornea. METHODS:Corneas from 15 human donors (age: 41-78 year...

journal_title：Acta ophthalmologica

authors： Kryczka T,Szaflik JP,Szaflik J,Midelfart A

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:Age-related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full-field electroretinography (ffERG) measures an electrical response, not...

journal_title：Acta ophthalmologica

authors： Forshaw TRJ,Kjaer TW,Andréasson S,Sørensen TL

更新日期：2020-08-24 00:00:00

abstract：PURPOSE:To assess the predictive value of optical coherence tomography (OCT) mapping of retinal thickness and intraretinal morphological changes after macular grid for diffuse diabetic macular oedema (DMO). METHODS:We carried out a prospective, non-controlled, case series study, in which 28 consecutive eyes with previ...

journal_title：Acta ophthalmologica

authors： Soliman W,Sander B,Soliman KA,Yehya S,Rahamn MS,Larsen M

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...

journal_title：Acta ophthalmologica

authors： Murakami Y,Ikeda Y,Nakatake S,Fujiwara K,Tachibana T,Yoshida N,Notomi S,Hisatomi T,Yoshida S,Ishibashi T,Sonoda KH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To assess the surgical and functional outcome of internal direct cyclopexy as therapy of complicated traumatic cyclodialysis. METHODS:The single-centre interventional case-series study included eyes with traumatic cyclodialysis who had consecutively been treated. Internal cyclopexy was performed using double-a...

journal_title：Acta ophthalmologica

authors： Wang C,Peng XY,You QS,Liu Y,Pang XQ,Zheng PF,Jonas JB

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To study anisometropia of spherical equivalent and astigmatism from the onset of myopia at school age to adulthood. METHODS:A total of 240 myopic schoolchildren (mean age 10.9 years), with no previous spectacles, were recruited during 1983-1984 to a randomized 3-year clinical trial of bifocal treatment of myop...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Aquaporins (AQPs) are widely expressed and have diverse distribution patterns in the eye. AQPs 0-5 have been localized at the cellular level in human eyes. We investigated the presence of the more recently discovered AQPs 6-12 in the human eye. METHODS:RT-PCR was performed on fresh tissue from two human eyes d...

journal_title：Acta ophthalmologica

authors： Tran TL,Bek T,Holm L,la Cour M,Nielsen S,Prause JU,Rojek A,Hamann S,Heegaard S

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to investigate the safety and efficacy of phacocanaloplasty with suprachoroidal drainage (PCscD) and to compare its intraocular pressure (IOP)-lowering and drug-sparing effect to canaloplasty with suprachoroidal drainage (CscD). METHODS:The study retrospective interventional study...

journal_title：Acta ophthalmologica

authors： Seuthe AM,Januschowski K,Mariacher S,Ebner M,Opitz N,Szurman P,Boden K

更新日期：2018-02-01 00:00:00