Intravitreal pegaptanib sodium (Macugen) for diabetic macular oedema.

abstract：PURPOSE:The present study aimed to investigate and compare the psychometric properties of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in a large sample of patients with cataracts. METHODS:A total of 1052 patients with bilateral age-related catara...

journal_title：Acta ophthalmologica

authors： Wan Y,Zhao L,Huang C,Xu Y,Sun M,Yang Y,An L,Lv S,Yu Y,Chen D,Zhou P,Wang Y,Zhang M,Jiang A,Chen Z,Li X

更新日期：2020-09-17 00:00:00

abstract：AIMS:This prospective, multicenter, single-masked study evaluated the additive effect of dorzolamide hydrochloride 2% on the diurnal intraocular pressure (IOP) curve and retinal and retrobulbar hemodynamics in patients with primary open-angle glaucoma (POAG) treated with morning-dosed bimatoprost 0.03%. METHODS:Eighty...

journal_title：Acta ophthalmologica

authors： Stankiewicz A,Misiuk-Hojło M,Grabska-Liberek I,Romanowska-Dixon B,Wierzbowska J,Wasyluk J,Mulak M,Szuścik I,Sierdziński J,Ehrlich R,Siesky B,Harris A

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To describe the clinical phenotype and the molecular pathology in a group of patients with congenital stationary night blindness due to mutations in GRM6, a gene encoding the ON bipolar metabotropic glutamate receptor 6 (mGluR6). METHODS:Nine patients from seven families (age range, 7-75; median, 10 years) wit...

journal_title：Acta ophthalmologica

authors： Sergouniotis PI,Robson AG,Li Z,Devery S,Holder GE,Moore AT,Webster AR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Complex segregation analysis of 60 unrelated sporadic keratoconus (KC) families was performed to reveal the presumed mode of inheritance in our dataset. METHODS:Sixty probands, 212 family members and 212 age and gender matched healthy controls underwent clinical and videokeratographic examination. Family aggre...

journal_title：Acta ophthalmologica

authors： Kriszt A,Losonczy G,Berta A,Vereb G,Takács L

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To characterize pre- and perioperative factors associated with treatment for wet age-related macular degeneration (wet AMD) after cataract surgery. METHODS:This register-based cohort study with data from the Swedish National Cataract Register (NCR) and the Swedish Macula Register (SMR) from 2010 to 2017 compar...

journal_title：Acta ophthalmologica

authors： Westborg I,Albrecht S,Granstam E,Karlsson N,Kugelberg M,Lundström M,Montan P,Behndig A

更新日期：2020-06-23 00:00:00

abstract：PURPOSE:To compare the efficacy and visual outcomes after femtosecond laser small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in correcting high myopia. METHODS:This prospective, randomized study included patients who underwent SMILE or FS-LASIK for the ...

journal_title：Acta ophthalmologica

authors： Qian Y,Chen X,Naidu RK,Zhou X

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To compare changes in macular pigment optical density (MPOD) and serum lutein concentration between free lutein and lutein esters supplements in healthy Japanese individuals. METHODS:Twenty healthy subjects (age range, 22-47 years) were recruited into this prospective, randomized, doubled-blind comparative stu...

journal_title：Acta ophthalmologica

authors： Yoshizako H,Hara K,Takai Y,Kaidzu S,Obana A,Ohira A

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. METHODS:This was a prospective, observati...

journal_title：Acta ophthalmologica

authors： Yamashita T,Kii Y,Tanaka M,Yoshinaga W,Yamashita T,Nakao K,Sakamoto T

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To present clinical results regarding the treatment of patients with age-related macular degeneration (neovascular form) after the implementation of a 'virtual' type of follow-up in a single retina service centre. METHODS:Retrospective study based on the clinical records of the Leicester Royal Infirmary Retina...

journal_title：Acta ophthalmologica

authors： Tsaousis KT,Empeslidis T,Konidaris VE,Kapoor B,Deane J

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To study the intraocular pressure (IOP)-reducing effect of deep sclerectomy on normal-tension glaucoma (NTG) patients. METHODS:We retrospectively analysed 21 eyes of 18 consecutive NTG patients who had undergone deep sclerectomy with mitomycin-C and a collagen implant. RESULTS:Median (range) preoperative IOP ...

journal_title：Acta ophthalmologica

authors： Suominen S,Harju M,Ihanamäki T,Vesti E

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:To evaluate the effect of intravitreal bevacizumab (Avastin; Genentech, Inc., San Francisco, CA, USA) (IVB) injection on prothrombin time (PT) in patients with proliferative diabetic retinopathy (PDR) and nondiabetic patients. METHODS:Eighty-nine patients received primary IVB (1.25 mg) in one eye were investig...

journal_title：Acta ophthalmologica

authors： Qian J,Jiang YR

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:This study aimed to determine the optimal spherocylindrical refraction in the monofocal, pseudophakic eye using power vectors in dioptric space. METHODS:For parallel incident light the defocus of a spherocylinder may be described in dioptric space as: Defocus equivalent for distance fixation = D((SEP,M,x=∞)) =...

journal_title：Acta ophthalmologica

authors： Naeser K,Hjortdal J

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To investigate the clinical features and outcomes of diffuse large B-cell lymphoma (DLBCL) involving the eye and ocular adnexa in an East Asian population and emphasize the importance of prompt biopsy and treatment in unusually progressive ocular adnexal DLBCL for better visual outcomes. METHODS:Retrospective ...

journal_title：Acta ophthalmologica

authors： Han SH,Kim YD,Jang J,Park JW,Young SM,Woo KI

更新日期：2021-01-09 00:00:00

abstract：PURPOSE:To compare structural and functional improvements in patients with vitreous haemorrhage (VH) with different IOPs re-established at the end of pars plana vitrectomy (PPV). METHODS:It is a prospective, randomized, comparative, interventional study. Ninety-five patients with nonclearing VH were randomized to rece...

journal_title：Acta ophthalmologica

authors： Zhou C,Zhang Z,Luo D,Gu C,Lahm T,Draga D,Qiu Q

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To assess the effect of donor tissue diameter in Descemet Membrane Endothelial Keratoplasty (DMEK) on postoperative endothelial cell density (ECD) mainly in Fuchs Endothelial Corneal Dystrophy (FECD) patients. METHODS:Retrospective review of 693 consecutive DMEK surgeries from the prospective Cologne DMEK data...

journal_title：Acta ophthalmologica

authors： Schrittenlocher S,Bachmann B,Cursiefen C

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To examine the heritability of corneal refraction power (CR) and corneal astigmatism (AST) in older women. METHODS:Corneal refraction and AST were measured by IOL master in 52 monozygotic (MZ) and 47 dizygotic (DZ) female twin pairs aged 66-79 years. The relative contribution of genetic and environmental facto...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M,Kaprio J,Koskenvuo M,Rantanen T

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:To test the expanded polytetrafluoroethylene (ePTFE) as a new adjuvant in trabeculectomy. METHODS:Consecutive glaucoma surgical inpatients were observed at the Department of Ophthalmology of Palermo University. Sixty patients (60 eyes) were randomly assigned to undergo trabeculectomy (T), trabeculectomy with m...

journal_title：Acta ophthalmologica

authors： Cillino S,Zeppa L,Di Pace F,Casuccio A,Morreale D,Bocchetta F,Lodato G

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To investigate the presence and distribution of l-kynurenine aminotransferases immunoreactivity in human and animal lenses during cataract formation. METHODS:Immunohistochemistry was conducted using polyclonal antibodies against KAT I, KAT II and KAT III on sections of 26 anterior capsules from patients underg...

journal_title：Acta ophthalmologica

authors： Rejdak R,Oleszczuk A,Rummelt C,Turski WA,Choragiewicz T,Nowomiejska K,Ksiazek K,Thaler S,Zarnowski T,Okuno E,Grieb P,Zrenner E,Kruse F,Junemann AG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To investigate the clinical efficacy and safety of an additional core vitrectomy to the standard therapy in patients with exudative age-related macular degeneration (ARMD). METHODS:In this prospective, controlled, single-centre study, 50 eyes of 50 patients (mean age: 74.1 ± 7.1; median 74 (69/78)) with ARMD w...

journal_title：Acta ophthalmologica

authors： Schramm K,Mueller M,Koch FH,Singh P,Kohnen T,Koss MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To assess the condition of the corneal endothelium an extended period after cataract surgery in eyes with and without pseudoexfoliation syndrome (PES). METHODS:Forty-six patients with PES who underwent cataract surgery in the Eye Department, Oslo University Hospital, in 2001 and 2002 were enrolled and compared...

journal_title：Acta ophthalmologica

authors： Ostern AE,Drolsum L

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland. METHODS:We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case historie...

journal_title：Acta ophthalmologica

authors： Baldursdóttir E,Sigurdsson H,Jónasson L,Gottfredsson M

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Choroideremia is a currently incurable X-linked recessive retinal degeneration that leads to blindness. Gene therapy approaches to date target the outer retinal layers. However, the choroideremia (CHM) gene is expressed in all retinal layers, and a previous study on a small cohort of choroideremia patients sugg...

journal_title：Acta ophthalmologica

authors： Fu DJ,Xue K,Jolly JK,MacLaren RE

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS:This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a ran...

journal_title：Acta ophthalmologica

authors： Rim TH,Han J,Choi YS,Lee T,Kim SS

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...

journal_title：Acta ophthalmologica

authors： Yuki K,Murat D,Kimura I,Tsubota K

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...

journal_title：Acta ophthalmologica

authors： Vazquez-Ferreiro P,Carrera-Hueso FJ,Fikri-Benbrahim N,Barreiro-Rodriguez L,Diaz-Rey M,Ramón Barrios MA

更新日期：2017-05-01 00:00:00

abstract：:Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...

journal_title：Acta ophthalmologica

authors： Kaplowitz K,Kuei A,Klenofsky B,Abazari A,Honkanen R

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Orally administered angiotensin II receptor blockers (ARBs) decrease intraocular pressure (IOP). Topical administration may reduce systemic side effects and result in a useful glaucoma drug. The aim of this study is to test the ocular delivery and pharmacologic effect of nanoparticle eye drops containing ARBs (...

journal_title：Acta ophthalmologica

authors： Lorenzo-Soler L,Olafsdottir OB,Garhöfer G,Jansook P,Kristinsdottir IM,Tan A,Loftsson T,Stefansson E

更新日期：2020-11-16 00:00:00

abstract：PURPOSE:To determine (i) whether, compared to controls, visual complaints of glaucoma patients are more pronounced under extreme luminance conditions than in the optimal luminance condition and (ii) whether complaints belonging to different extreme luminance conditions are associated. METHODS:We developed a luminance-...

journal_title：Acta ophthalmologica

authors： Bierings RAJM,van Sonderen FLP,Jansonius NM

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:The aim of the study was to describe the prevalence of visual impairment and retinopathy and to investigate risk factors for retinopathy in persons with diabetes, screen-detected diabetes, impaired glucose tolerance and normal glucose tolerance in a subpopulation of the HUNT study. METHODS:We used a sample (n ...

journal_title：Acta ophthalmologica

authors： Sundling V,Platou CG,Jansson RW,Bertelsen G,Wøllo E,Gulbrandsen P

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS:Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn...

journal_title：Acta ophthalmologica

authors： Bacci GM,Donati MA,Pasquini E,Munier F,Cavicchi C,Morrone A,Sodi A,Murro V,Garcia Segarra N,Defilippi C,Bussolin L,Caputo R

更新日期：2017-12-01 00:00:00