Abstract:
PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey literature sources and identified (on March 1, 2016) 14 cohort and case-control studies comparing IOL dislocation in patients with and without pseudoexfoliation syndrome who had undergone phacoemulsification. Study quality was assessed using the STROBE scale. An inverse-variance fixed-effects model was used to calculate weighted odds ratios (ORs) and 95% confidence intervals (CI). RESULTS:The pooled analysis yielded an OR of 6.02 (95% CI: 3.7, 9.79) for IOL dislocation in patients with pseudoexfoliation, and similarly, high ORs were detected for both early and late (3 months after surgery) dislocation (OR 5.26; 95% CI: 1.05; 26.32 versus OR 6.02; 95% CI: 3.67; 10.17). No significant associations were detected when the results were stratified by year, incision size or use of hooks or retractors. CONCLUSIONS:Patients with pseudoexfoliation syndrome have a high risk of late IOL dislocation after phacoemulsification cataract surgery, and this risk may be related to the use of large incisions and hooks or retractors.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Vazquez-Ferreiro P,Carrera-Hueso FJ,Fikri-Benbrahim N,Barreiro-Rodriguez L,Diaz-Rey M,Ramón Barrios MAdoi
10.1111/aos.13234subject
Has Abstractpub_date
2017-05-01 00:00:00pages
e164-e169issue
3eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
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