Inhibition of ocular neovascularization by a novel peptide derived from human placenta growth factor-1.

abstract：:Ziv-aflibercept (Zaltrap® ), a recombinant fusion protein that binds diffusible vascular endothelial growth factor (VEGF), is approved for the treatment of metastatic colorectal carcinoma. Its molecular structure is the same as aflibercept (Eylea® ), thus making it an attractive option for the off-label treatment of c...

journal_title：Acta ophthalmologica

authors： Mansour AM,Stewart MW,Farah ME,Mansour HA,Chhablani J

更新日期：2019-12-20 00:00:00

abstract：:Although the work for which Emil von Behring (1854-1917) was awarded the first Nobel Prize Winner for Medicine or Physiology in 1901 was on serum therapy, not only was he trained and worked as an ophthalmologist but he also wrote his doctoral dissertation on a practical ophthalmological topic whilst in Berlin under Ca...

journal_title：Acta ophthalmologica

authors： Grzybowski A,Wilhelm H

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:The present study aimed to investigate and compare the psychometric properties of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in a large sample of patients with cataracts. METHODS:A total of 1052 patients with bilateral age-related catara...

journal_title：Acta ophthalmologica

authors： Wan Y,Zhao L,Huang C,Xu Y,Sun M,Yang Y,An L,Lv S,Yu Y,Chen D,Zhou P,Wang Y,Zhang M,Jiang A,Chen Z,Li X

更新日期：2020-09-17 00:00:00

abstract：PURPOSE:This study aimed to investigate the rise in aqueous humour (AH) levels of levofloxacin after a specific perioperative pulsed topical drop regimen. METHODS:Thirty patients undergoing phacoemulsification surgery were administered two preoperative drops of levofloxacin 0.5%, 30 mins apart, and three pulsed drops ...

journal_title：Acta ophthalmologica

authors： Sundelin K,Seal D,Gardner S,Ropo A,Geldsetzer K,Lokkila J,Stenevi U

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:Diabetic retinopathy is diagnosed by fundus photography and optical coherence tomography (OCT) scanning. However, adaptive optics (AO) imaging can be expected to add new aspects to the knowledge of diabetic retinopathy because photographic resolution is improved by reducing the influence of optical aberrations ...

journal_title：Acta ophthalmologica

authors： Bek T

更新日期：2014-12-01 00:00:00

abstract：:There is still no agreement on total plasma homocysteine (tHcy) role in age-related macular degeneration (AMD), the leading cause of new blindness in industrialized countries. We performed a systematic review and meta-analysis of the published data on the correlation between tHcy and AMD. MEDLINE/PubMed and ISI Web of...

journal_title：Acta ophthalmologica

authors： Pinna A,Zaccheddu F,Boscia F,Carru C,Solinas G

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:A free autologous retinal pigment epithelium (RPE)-choroid graft can be harvested during transplantation surgery from a 6 or 12 o'clock site in the midperiphery. This study evaluated whether proliferative vitreoretinopathy (PVR) occurs more frequently in patients with an inferior donor site retinotomy, which is...

journal_title：Acta ophthalmologica

authors： van Zeeburg EJ,Maaijwee K,van Meurs JC

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:Photodynamic riboflavin/ultraviolet-A (UVA)-induced collagen cross-linking, which increases the biomechanical stiffness of the human cornea by about 300%, has been introduced recently as a possible treatment for progressive keratoconus. The present study was undertaken to evaluate the longterm biomechanical eff...

journal_title：Acta ophthalmologica

authors： Wollensak G,Iomdina E

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To determine whether the hill of vision for Short-Wavelength Automated Perimetry (SWAP) is shallower for women who consume phyto-oestrogen-rich foods than for women who do not. METHODS:Visual field data were compared for two groups of healthy amenorrhoeic women 48-69 years-old with normal vision and not using ...

journal_title：Acta ophthalmologica

authors： Eisner A,Demirel S

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To examine preoperative anti-inflammatory treatment on recovery from cataract surgery in eyes of diabetic patients. METHODS:A Prospective randomized clinical trial. One hundred and three eyes of 103 patients with diabetes undergoing routine cataract surgery were randomized (1:1) not to receive any preoperative...

journal_title：Acta ophthalmologica

authors： Danni R,Viljanen A,Aaronson A,Tuuminen R

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS:Data from 139 patients with conjunctival mela...

journal_title：Acta ophthalmologica

authors： Larsen AC,Dahl C,Dahmcke CM,Lade-Keller J,Siersma VD,Toft PB,Coupland SE,Prause JU,Guldberg P,Heegaard S

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS). METHODS:The wireless CLS is a disposable silicone soft contact lens with a sensor embedded in it, allowing the wireless me...

journal_title：Acta ophthalmologica

authors： Leonardi M,Pitchon EM,Bertsch A,Renaud P,Mermoud A

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS:Cross-sectional stu...

journal_title：Acta ophthalmologica

authors： van Nispen R,van der Aa H,Timmermans F,Meijer N,Koster N,de Blok J,Keunen J,van Rens G

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To report the prevalence of pseudoexfoliation (PEX) syndrome and glaucoma associated with PEX (PEX-G) and their relating factors of them in a south-western island of Japan. METHODS:A population-based survey of all residents aged ≥ 40 years was conducted in Kumejima, Okinawa, Japan, and 3762 subjects (participa...

journal_title：Acta ophthalmologica

authors： Arakaki Y,Sawaguchi S,Iwase A,Tomidokoro A,Araie M

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:To report the postoperative results after enucleation of using an acrylic orbital implant covered in donor sclera for implantation. METHODS:We retrospectively analysed the charts of patients who were enucleated between 2007 and 2011. Only patients who received an acrylic implant covered with donor sclera were ...

journal_title：Acta ophthalmologica

authors： Jongman HP,Marinkovic M,Notting I,Koetsier L,Swart W,Schalij-Delfos NE,Bleeker J,Jager MJ,Luyten GP

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To investigate the value of posterior keratometry in the assessment of surgically induced astigmatic change (AC) in cataract surgery, with particular emphasis on the influence of test-retest variability. METHODS:Seventy-seven eyes of 77 cataract patients scheduled for routine cataract surgery were enrolled. Al...

journal_title：Acta ophthalmologica

authors： Klijn S,van der Sommen CM,Sicam VA,Reus NJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:The clinical use and comparison of two recently developed A-scan ultrasound devices. METHODS:The same investigator determined central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) with an OcuScan RxP (Alcon, Forth Worth, Texas, USA) and an AL-2000 (Tomey, Erlangen, Germany) ultras...

journal_title：Acta ophthalmologica

authors： Sohajda Z,Papp J,Berta A,Módis L

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep vessel density (DVD) and their correlation with functional (best-corrected visual acuity, BCVA) and anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RR...

journal_title：Acta ophthalmologica

authors： Bonfiglio V,Ortisi E,Scollo D,Reibaldi M,Russo A,Pizzo A,Faro G,Macchi I,Fallico M,Toro MD,Rejdak R,Nowomiejska K,Toto L,Rinaldi M,Cillino S,Avitabile T,Longo A

更新日期：2019-11-26 00:00:00

abstract：PURPOSE:To characterize frequency, morphological cause and time-dependent change of boundary line artefacts in optical coherence tomography (OCT) examinations of centre-involved diabetic macular oedema (ciDME) patients who underwent ranibizumab treatment with 1-year follow-up and to evaluate the impact of artefacts on ...

journal_title：Acta ophthalmologica

authors： Hodzic-Hadzibegovic D,Sander BA,Lund-Andersen H

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:To determine the spectrum of BEST1 mutations and to study the phenotype in Slovenian families with Best vitelliform macular dystrophy (BVMD) to identify genotype-phenotype correlations. METHODS:Twenty patients from five families underwent the ophthalmological examination including electrooculogram (EOG; N = 17...

journal_title：Acta ophthalmologica

authors： Glavač D,Jarc-Vidmar M,Vrabec K,Ravnik-Glavač M,Fakin A,Hawlina M

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of big-bubble (BB) technique in separating Dua's layer together with the Descemet's membrane endothelial (DE) graft and the effect of 7-day storage of the prepared tissues on the endothelial cells. METHOD:This is an experimental study in which 21 human corneo-scleral tissues unsuitable...

journal_title：Acta ophthalmologica

authors： GamalElDin SA,Salama MM,ElShazly MI

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To examine the correlation between health-related quality of life (HRQOL) scores [assessed using the generic Short Form Health Survey (SF-36) questionnaire] and vision-related quality of life (VRQOL) scores [assessed using the National Eye Institute Visual Function Questionnaire (NEI-VFQ25)]. METHODS:Cross-sec...

journal_title：Acta ophthalmologica

authors： Swamy BN,Chia EM,Wang JJ,Rochtchina E,Mitchell P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To test the validity of the eyesi surgical simulator as an assessment tool in a virtual reality vitreoretinal training programme. METHODS:In collaboration with an experienced vitreoretinal surgeon, a virtual vitreoretinal training programme was composed on the eyesi surgical simulator, software version 2.9.2 (...

journal_title：Acta ophthalmologica

authors： Vergmann AS,Vestergaard AH,Grauslund J

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Photoscreening assesses risk factors for amblyopia, as an alternative to measurement of visual acuity (VA) to detect amblyopia, on the premise that its early correction could prevent development of amblyopia. We studied implementations of Plusoptix photoscreening in existing population-based screening in Flande...

journal_title：Acta ophthalmologica

authors： Bostamzad P,Horwood AM,Schalij-Delfos NE,Boelaert K,de Koning HJ,Simonsz HJ

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Enzyme replacement therapy (ERT) was offered from year 2001 to patients with Fabry disease. The ophthalmic experience was analysed, as part of a general 10-year status. METHODS:A retrospective observational series comprising 39 patients (25 females, 14 males) closely followed by the endocrinologists, and with ...

journal_title：Acta ophthalmologica

authors： Fledelius HC,Sandfeld L,Rasmussen ÅK,Madsen CV,Feldt-Rasmussen U

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To evaluate intraocular pressure (IOP) control over 24 hours using travoprost and timolol fixed combination (TTFC) administered in the morning or evening in primary open-angle and exfoliative glaucoma. METHODS:Patients were randomized to TTFC administered in either the morning or evening for 8 weeks. Previousl...

journal_title：Acta ophthalmologica

authors： Konstas AG,Tsironi S,Vakalis AN,Nasr MB,Stewart JA,Nelson LA,Stewart WC

更新日期：2009-02-01 00:00:00

abstract：:Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

journal_title：Acta ophthalmologica

authors： Hajari JN

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To identify causes of reduced visual acuity after Descemet stripping (automated) endothelial keratoplasty (DSEK/DSAEK) and to determine whether such eyes can be successfully 'repaired' with a secondary Descemet membrane endothelial keratoplasty (DMEK). METHODS:Twelve eyes of 12 patients, who underwent secondar...

journal_title：Acta ophthalmologica

authors： Dirisamer M,Parker J,Naveiras M,Liarakos VS,Ham L,van Dijk K,Melles GR

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Tissue inhibitors of metalloproteinases (TIMPs) block the catalysis by matrix metalloproteinases (MMPs) and have additional biologic activities, including regulation of cell growth and differentiation, apoptosis, angiogenesis and oncogenesis. We investigated the expression levels of all the four human TIMPs and...

journal_title：Acta ophthalmologica

authors： Abu El-Asrar AM,Ahmad A,Bittoun E,Siddiquei MM,Mohammad G,Mousa A,De Hertogh G,Opdenakker G

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Current fundus imaging in newborn babies requires mydriatics, eye specula and corneal contact. We propose that a scanning laser ophthalmoscope (SLO) allows ultra wide-field imaging with reduced stress for the child. METHODS:This prospective observational single centre study was conducted in Landspítali, Univer...

journal_title：Acta ophthalmologica

authors： Magnusdottir V,Vehmeijer WB,Eliasdottir TS,Hardarson SH,Schalij-Delfos NE,Stefánsson E

更新日期：2017-12-01 00:00:00