Abstract:
PURPOSE:This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS:This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a randomly selected, propensity-matched control cohort (n = 2281) were extracted from the Korean national insurance claim database. Subjects were tracked for 5 years total, subdivided into periods of 0-1 years, 1-3 years and 3-5 years. We assessed the risk of stroke using hazard ratios (HRs) and confidence intervals (CIs) after adjustments using Cox regression at different time intervals. RESULTS:The median follow-up was 3.1 years. Stroke developed in 18.9% of the NP cohort and 7.5% of the control cohort. Stroke risk after NP was highest in the first year [14.7 per 100 person-year at 0-1 years (HR = 6.6), 3.1 per 100 person-year at 1-3 years (HR = 1.6) and 4.3 per 100 person-year at 3-5 years (HR = 2.8)]. Each type of NP was also associated with stroke risk: within 0-1 years, stroke risk was increased in third (HR = 7.6), fourth (HR = 6.0) and sixth (HR = 5. 84) NPs. In the 3- to 5-year period, risk was increased in sixth (HR = 4.7) and fourth (HR = 3.3) NPs, but not third (HR = 0.6) NPs. CONCLUSION:Patients in the NP cohort were more likely to have a stroke than those in the matched control cohort; the increased risk was both time- and cranial nerve-dependent.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Rim TH,Han J,Choi YS,Lee T,Kim SSdoi
10.1111/aos.13488subject
Has Abstractpub_date
2017-11-01 00:00:00pages
e656-e661issue
7eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
杂志文章,多中心研究abstract:PURPOSE:Aquaporins (AQPs) are widely expressed and have diverse distribution patterns in the eye. AQPs 0-5 have been localized at the cellular level in human eyes. We investigated the presence of the more recently discovered AQPs 6-12 in the human eye. METHODS:RT-PCR was performed on fresh tissue from two human eyes d...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02547.x
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To evaluate the diagnostic capacity of the Ocular Response Analyser's keratoconus match index (KMI) and keratoconus match probability (KMP) classification in a sample of keratoconus (KC) patients. METHODS:Keratoconus match index and KMP from 114 KC eyes, randomly selected from 114 patients with bilateral kerat...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12056
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:We aimed to determine prospectively the incidence of abnormal test results on frequency doubling perimetry (FDT), the nerve fibre analyser (GDx) and standard automated perimetry (SAP) in a cohort of glaucoma suspect patients with normal findings for all these tests at baseline. METHODS:Seventy glaucoma suspect...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01279.x
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS:Data from 139 patients with conjunctival mela...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13007
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14333
更新日期:2019-12-29 00:00:00
abstract:PURPOSE:To evaluate short- and long-term intraocular pressure (IOP) changes after temporal clear corneal phacoemulsification in normal eyes. METHODS:The charts of 266 consecutive non-glaucoma patients who underwent uneventful cataract surgery were reviewed. We recorded preoperative and postoperative (1 day, 1 week, 1 ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01569.x
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To evaluate the clinical course after early surgical treatment with excision of retinal hemangioblastomas (RHs) before development of major complications. METHODS:Interventional case series of four eyes (four patients) with a peripheral RH that had not yet been treated by laser or cryotherapy prior to surgery....
journal_title:Acta ophthalmologica
pub_type:
doi:10.1111/aos.13223
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:To investigate the associations between ocular pulse amplitude (OPA) as measured by dynamic contour tonometry (DCT) and ocular and systemic factors in patients with open angle glaucoma (OAG) and in glaucoma suspects. METHODS:One hundred and seventy-three glaucoma-suspect patients were consecutively enrolled. A...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01954.x
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:This work aimed to study and evaluate the effect of subconjunctival bevacizumab injection in patients with corneal neovascularization (CNV) resulting from different ocular surface disorders. METHODS:Ten eyes with CNV caused by different ocular surface disorders were studied. All eyes had both major and minor v...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01585.x
更新日期:2010-12-01 00:00:00
abstract::Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2008.01210.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To report complications after the implantation of intrastromal corneal ring segments (Keraring; Mediphacos, Belo Horizonte, Brazil) in keratoconic eyes using a femtosecond laser (IntraLase; Advanced Medical Optics, Santa Ana, California, USA) for channel creation. METHODS:Retrospective chart review of 531 pati...
journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1755-3768.2009.01605.x
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13173
更新日期:2017-02-01 00:00:00
abstract::Working at the nanoscale means to completely rethink how to approach engineering in the body in general and in the eye in particular. In nanomedicine, tissue engineering is the ability to influence an environment either by adding, subtracting or manipulating that environment to allow it to be more conducive for its pu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2010.01982.x
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14717
更新日期:2021-01-02 00:00:00
abstract:PURPOSE:This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland. METHODS:We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case historie...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01367.x
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To investigate whether introduction of item-response theory (IRT) analysis, in parallel to the 'traditional' statistical analysis methods available for performance evaluation of multiple T/F items as used in the European Board of Ophthalmology Diploma (EBOD) examination, has proved beneficial, and secondly, to ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12135
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To evaluate the effect of photodynamic therapy (PDT) on central serous chorioretinopathy (CSC) compared with laser therapy and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs, and to find the maximum treatment effect with minimal dose and fluence of PDT. METHODS:A systematic...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/aos.12482
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To study the genetic aetiology of retinal dystrophies (RD) in Finnish patients. METHODS:A targeted next-generation sequencing (NGS) panel of 105 retinal dystrophy genes was used in a cohort of 55 RD patients. RESULTS:The overall diagnostic yield was 60% demonstrating the power of this approach. Interestingly,...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13551
更新日期:2018-03-01 00:00:00
abstract:UNLABELLED:In this thesis the term eye amputation (EA) covers the removing of an eye by: evisceration, enucleation and exenteration. Amputation of an eye is most frequently the end-stage in a complicated disease, or the primary treatment in trauma and neoplasm. In 2010 the literature is extensive due to knowledge about...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.02039.x
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Posterior capsule opacification (PCO) occurs as a common complication after cataract surgery. Erlotinib is an inhibitor of the epidermal growth factor-Receptor and reduces critical cellular events leading to PCO. In this in vitro study, Erlotinib-modified intraocular lenses (IOLs) employed as a drug delivery de...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13759
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To investigate the feasibility, effectiveness and acceptability of using prosthetic occluding contact lenses (OCLs) to treat moderate amblyopia in adults and of the role of the multifocal visual evoked potential (mfVEP) as a predictor of postamblyopic therapy. METHODS:A comparative, prospective, interventional...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.13585
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To study the effect of glaucoma drainage implant (GDI) surgery on corneal topography during the first postoperative year. METHODS:Twenty-one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 GDI. Corneal topography measurements were taken preoperatively and at 6 and 12 months after surg...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14247
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To investigate the reproducibility of Bruch's membrane opening minimum rim width (BMO-MRW) and retinal nerve fibre layer thickness (RNFLT) measurements using spectral domain optical coherence tomography (SD-OCT). Additionally, to investigate the reproducibility of BMO area measurements and fovea to BMO centre (...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13464
更新日期:2017-11-01 00:00:00
abstract::This literature review is aimed at the evaluation of the potential for cataract prevention in Europe. It was performed using PubMed with Mesh and free-text terms. Studies included were (i) performed on a population of Caucasian origin at an age range of 40-95 years, (ii) cataract was clinically verified, (iii) drug re...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2012.02444.x
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To investigate whether exposure to antazoline-naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans. METHODS:All women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at le...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13980
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To investigate the presence and distribution of l-kynurenine aminotransferases immunoreactivity in human and animal lenses during cataract formation. METHODS:Immunohistochemistry was conducted using polyclonal antibodies against KAT I, KAT II and KAT III on sections of 26 anterior capsules from patients underg...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12138
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To compare the efficacy and visual outcomes after femtosecond laser small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in correcting high myopia. METHODS:This prospective, randomized study included patients who underwent SMILE or FS-LASIK for the ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.14078
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To compare structural and functional improvements in patients with vitreous haemorrhage (VH) with different IOPs re-established at the end of pars plana vitrectomy (PPV). METHODS:It is a prospective, randomized, comparative, interventional study. Ninety-five patients with nonclearing VH were randomized to rece...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14293
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:A free autologous retinal pigment epithelium (RPE)-choroid graft can be harvested during transplantation surgery from a 6 or 12 o'clock site in the midperiphery. This study evaluated whether proliferative vitreoretinopathy (PVR) occurs more frequently in patients with an inferior donor site retinotomy, which is...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12178
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To compare the postoperative anatomic success rates and the frequency of complications between prone or supine postoperative positioning after transconjunctival sutureless vitrectomy (TSV) for rhegmatogenous retinal detachment (RRD). METHODS:All patients underwent primary 27-gauge TSV for the treatment of prim...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13482
更新日期:2018-03-01 00:00:00