Abstract:
PURPOSE:To compare the outcomes of microcatheter-assisted circumferential trabeculotomy to standard rigid probe trabeculotomy in childhood glaucomas. METHODS:Eyes of children requiring trabeculotomy for primary congenital or secondary paediatric glaucoma were randomized to undergo either trabeculotomy using the Glaucolight illuminated microcatheter, or a rigid probe trabeculotomy. Complete success was defined as an intraocular pressure (IOP) of <18 mmHg without medications. RESULTS:A total of 62 eyes of 62 patients were included. Of these 30 eyes of 30 patients aged 5.6 ± 4.8 months underwent microcatheter-assisted trabeculotomy, with 15 eyes (50%) having a complete 360° cut, while 15 eyes (50%) had an incomplete cut ranging from 250 to 350 degrees. The rigid probe trabeculotomy group included 32 eyes of 32 patients aged 4.4 ± 3.8 months. At the end of the 2-year follow-up period, the complete success and the failure rates were 67% and 15%, respectively, in the microcatheter-assisted group versus 47% and 50% in the rigid probe trabeculotomy group (p = 0.006). There was a tendency towards lower IOP in the microcatheter group at 1, 3, 6, 12 and 24 months postoperatively, with the difference in IOP reaching statistical significance at 6 months (p = 0.004). The mean survival time was significantly longer for the microcatheter group (p = 0.01). CONCLUSION:At 2 years postoperatively, microcatheter-assisted trabeculotomy still yielded superior results in terms of IOP control and success rates in children with primary congenital glaucoma. The need for reoperation for glaucoma was significantly lower in the microcatheter group.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
El Sayed Y,Gawdat Gdoi
10.1111/aos.13414subject
Has Abstractpub_date
2017-12-01 00:00:00pages
e713-e719issue
8eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
杂志文章,随机对照试验abstract::Data on the association between hypothyroidism and glaucoma are conflicting. We sought to shed light on this by conducting a critical review and meta-analyses. The meta-analyses were conducted in adherence with the widely accepted MOOSE guidelines. Using the Medical Subject Heading (MeSH) terms: hypothyroidism, myxoed...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/aos.13412
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To analyse the anterior lens capsule thickness and ultrastructure changes of intumescent white cataracts in comparison with nuclear cataracts to prove possible structural reasons for surgical difficulties with the intumescent white cataract. METHODS:Anterior lens capsules from 35 eyes with intumescent white an...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.02102.x
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To determine the myopia prevalence in Hong Kong Chinese children and their parents. METHODS:It was a population-based cross-sectional study. A total of 4257 children aged 6-8 years, and 5880 parents were recruited in the Hong Kong Children Eye Study. Cycloplegic autorefraction was measured for children; and no...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14350
更新日期:2020-01-24 00:00:00
abstract:PURPOSE:Previous studies have indicated that the immune system is involved in the pathogenesis of the AMD. Increased visceral fat, in addition, has a pro-inflammatory effect on the organism by producing or influencing different kinds of inflammatory factors. The aim of this study is to determine the relationship of bod...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12670
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:To study high-resolution ultrasound biomicroscopy (UBM) findings in anterior scleral inflammatory disease and evaluate the efficacy of high-resolution UBM as an adjunctive diagnostic tool. METHODS:A cross-sectional study. The medical records of 30 patients (33 eyes) with episcleritis or anterior scleritis were...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12995
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS:This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13513
更新日期:2018-03-01 00:00:00
abstract::Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2008.01210.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To evaluate the biomechanical properties of the cornea using Corneal Visualization Scheimpflug Technology (CorVis ST, Oculus) in eyes with primary open-angle glaucoma (POAG) and normal control eyes. METHODS:A comparative cross-sectional study that included 42 patients with POAG and 60 normal control subjects m...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12672
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To investigate the incidence and cause of severe visual loss following use and removal of intraocular silicone oil (SiO) after uncomplicated vitrectomy and SiO injection for primary rhegmatogenous retinal detachment (RRD). METHODS:Consecutive case series of 216 patients operated with vitrectomy for primary RRD...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02248.x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To establish whether or not the dynamics of saccadic eye movements are significantly changed in patients with different stages of thyroid-associated ophthalmopathy (TAO) and, subsequently, if analysis of saccades could serve as an additional diagnostic tool for early detection of inflammatory activity in TAO. ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02216.x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To compare pars plana vitrectomy and 360° endolaser therapy with pars plana vitrectomy and an encircling scleral buckle for the treatment of primary rhegmatogenous retinal detachments in a randomized pilot study including 60 patients. METHODS:Main outcome measures were single-surgery anatomic success rate and ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.12663
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13047
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS:Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic crite...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13647
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:Age-related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full-field electroretinography (ffERG) measures an electrical response, not...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14571
更新日期:2020-08-24 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of 1.5% dexamethasone nanoparticle (DexNP) drops in eyes with non-infectious uveitic macular oedema and vitritis. METHODS:In a prospective pilot study, DexNP drops were administered four times a day for 4 weeks followed by drops tapering over a period of another 4 weeks. Fol...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12744
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To report our experiences of treating periocular capillary haemangioma with particular emphasis on visual outcomes. METHODS:Patients who underwent treatment for periocular capillary haemangioma were identified, and a chart review was performed. RESULTS:There were seventeen patients in the study. The main indi...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01789.x
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To evaluate short- and long-term intraocular pressure (IOP) changes after temporal clear corneal phacoemulsification in normal eyes. METHODS:The charts of 266 consecutive non-glaucoma patients who underwent uneventful cataract surgery were reviewed. We recorded preoperative and postoperative (1 day, 1 week, 1 ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01569.x
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND/AIMS:The mitotic count of uveal melanomas correlates with the risk of metastatic death, but with haematoxylin and eosin (H&E)-stained sections, it can be difficult to identify mitotic figures (MF) reliably. We investigated whether this measurement could be enhanced by immunohistochemistry, using the mitosis-...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01769.x
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Study the clinical and microbiological characteristics and the prognostic factors of post-traumatic endophthalmitis. METHODS:Seventeen eyes were included between 2004 and 2010, with clinical and microbiological data collected prospectively. Conventional cultures and panbacterial PCR were performed on aqueous a...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1755-3768.2011.02349.x
更新日期:2013-08-01 00:00:00
abstract::This literature review is aimed at the evaluation of the potential for cataract prevention in Europe. It was performed using PubMed with Mesh and free-text terms. Studies included were (i) performed on a population of Caucasian origin at an age range of 40-95 years, (ii) cataract was clinically verified, (iii) drug re...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2012.02444.x
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:We aimed to evaluate the effectiveness of bicanalicular double silicone intubation in dacryocystorhinostomy (DCR) and canaliculoplasty for distal or common canalicular obstruction. METHODS:We reviewed the medical records of patients with distal or common canalicular obstruction who had undergone bicanalicular ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01292.x
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To determine whether bilateral implantation of an aspheric apodized diffractive multifocal intraocular lens (IOL) with +3.00 diopters (D) results in optical adverse effects compared with an aspheric monofocal IOL. METHODS: In a prospective, randomized study of 204 eyes (102 patients) with bilateral implantati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1755-3768.2012.02497.x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To investigate the clinical efficacy and safety of an additional core vitrectomy to the standard therapy in patients with exudative age-related macular degeneration (ARMD). METHODS:In this prospective, controlled, single-centre study, 50 eyes of 50 patients (mean age: 74.1 ± 7.1; median 74 (69/78)) with ARMD w...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.12326
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:Keratoconus is a progressive disorder and one of the primary indications for corneal transplantation. Anterior lamellar keratoplasty offers several advantages over other techniques, including endothelial preservation and longer graft survival. In this study, we examined the recent trend of using lamellar techni...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13041
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Congenital anophthalmia (A) and microphthalmia (M) are rare developmental defects, which could be isolated or syndromic. Our objective was to describe a cohort of children and young adults with A/M treated with ocular prosthesis, emphasizing clinical features, diagnosis, treatment, and follow-up. METHODS:Eight...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14427
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:This study aimed to investigate intraocular pressure (IOP) measurements taken using the dynamic contour tonometer (DCT) and the non-contact tonometer (NCT) in subjects with keratoconus. METHODS:Intraocular pressure was measured in 20 keratoconus subjects and 20 age-matched control subjects using the DCT and NC...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01690.x
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:We investigated the natural course of the intraretinal hyperreflective (IRH) sign after macular haemorrhage (MHE) absorption in eyes with pathologic myopia. METHODS:This prospective observational cohort study evaluated 28 patients with pathologic myopia and MHE. The eyes were categorized into IRH and non-IRH s...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14332
更新日期:2019-12-06 00:00:00
abstract:PURPOSE:The aim of this study was to analyse 69 Chinese patients with USH2A mutations and to assess the genotype-phenotype correlation. METHODS:All 36 Usher syndrome type IIA patients and 33 nonsyndromic RP (retinitis pigmentosa) patients underwent clinical examinations. Eye examinations included best-corrected visual...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14626
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:To report normative data on visual acuity (VA) for near and distance, refraction, ocular alignment, ocular motility and stereo acuity in a cohort of children aged 4.5-7 years. METHODS:A total of 950 children with normal development from the municipality of Roskilde, Denmark, were invited to participate in an o...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13650
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:To evaluate a pro re nata administration of Ozurdex® implant versus a single administration for treating diabetic macular oedema (DME). METHODS:This exploratory study is designed as a comparative, multicentre, randomized study with a follow-up of 6 months. Patients with DME were assigned to treatment at baseli...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/aos.13395
更新日期:2017-06-01 00:00:00