A multicentre prospective study of post-traumatic endophthalmitis.

Abstract:

PURPOSE:Study the clinical and microbiological characteristics and the prognostic factors of post-traumatic endophthalmitis. METHODS:Seventeen eyes were included between 2004 and 2010, with clinical and microbiological data collected prospectively. Conventional cultures and panbacterial PCR were performed on aqueous and vitreous samples. RESULTS:Clinical signs of endophthalmitis were observed soon after trauma (1.5 ± 2.5 days). Laceration with an intraocular foreign body (IOFB) was noted in 53% of the patients. At admission, all patients had aqueous humour (71%) and/or vitreous (53%) samples. Fifteen patients (88%) underwent a pars plana vitrectomy. Bacteria were identified in 77% of the cases: Staphylococcus epidermidis (n = 5), Streptococcus (n = 4), Bacillus (n = 2), Pseudomonas stuzeri (n = 1), and Streptococcus salivarius and Gemella haemolysans (multibacterial infection, n = 1). Progression toward phthisis was observed in 35% of the cases; 41% of the patients recuperated visual acuity (VA) ≥20/40. A good final visual prognosis (≥20/40) was significantly associated with initial VA better than light perception (0% versus 70%, p = 0.01) and absence of pupillary fibrin membrane (80% versus 20%, p = 0.05). There was no correlation between visual prognosis and age, the type of laceration (corneal or scleral) or presence of an IOFB. We found a statistical trend toward an association between bacterial virulence and poor final VA. CONCLUSION:This series showed that better final VA outcomes were associated with initial VA better than light perception, S. epidermidis or culture-negative cases and absence of retinal detachment during the clinical course.

journal_name

Acta Ophthalmol

journal_title

Acta ophthalmologica

authors

Cornut PL,Youssef el B,Bron A,Thuret G,Gain P,Burillon C,Romanet JP,Vandenesch F,Maurin M,Creuzot-Garcher C,Chiquet C,French Institutional Endophthalmitis Study (FRIENDS) Group.

doi

10.1111/j.1755-3768.2011.02349.x

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

475-82

issue

5

eissn

1755-375X

issn

1755-3768

journal_volume

91

pub_type

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