Prognostic factors in vitrectomy for lamellar macular hole assessed by spectral-domain optical coherence tomography.

Abstract:

PURPOSE:To evaluate the association between the macular structure on spectral-domain optical coherence tomography (SD-CT) and visual outcome after vitrectomy for lamellar macular hole (LMH). METHODS:Best-corrected visual acuity (VA) and SD-OCT images of the macula were assessed before and after surgery in 30 eyes of 30 patients with a LMH. Preoperative VA and SD-OCT features were investigated as predictors of surgical outcome. RESULTS:Mean patient age was 65 years with female predominance (77%). Visual acuity improved in 19 eyes (63%) with an overall mean improvement of 1 Snellen line (from 20/65 to 20/50; p = 0.002) at a mean of 18 months after vitrectomy. Subgroup analysis showed that statistically significant visual benefit was only observed in patients with an intact photoreceptor inner segment/outer segment (IS/OS) junction (p = 0.003), with foveal thickness bigger than 100 μm (p = 0.004) and with initial VA better than 20/100 (p = 0.003). The most efficient model to predict final VA was the combination of preoperative VA and the presence or absence of IS/OS disruption (r(2) = 0.77, p < 0.001). CONCLUSIONS:Poor initial VA, the presence of a disrupted IS/OS junction or a thin fovea on preoperative SD-OCT predicted poor vision outcome after LMH surgery.

journal_name

Acta Ophthalmol

journal_title

Acta ophthalmologica

authors

Lee CS,Koh HJ,Lim HT,Lee KS,Lee SC

doi

10.1111/j.1755-3768.2012.02456.x

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

e597-602

issue

8

eissn

1755-375X

issn

1755-3768

journal_volume

90

pub_type

杂志文章
  • Ocular blood flow in glaucoma - the Leuven Eye Study.

    abstract:PURPOSE:Elevated intra-ocular pressure (IOP) has been identified as a major risk factor for glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these patients. However, a large ocular blood flow-oriented trial to integrate these findings in the clinical setting is lacking. This study...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12962

    authors: Abegão Pinto L,Willekens K,Van Keer K,Shibesh A,Molenberghs G,Vandewalle E,Stalmans I

    更新日期:2016-09-01 00:00:00

  • Corneal endothelial cells 6-7 years following cataract surgery in patients with pseudoexfoliation syndrome.

    abstract:PURPOSE:To assess the condition of the corneal endothelium an extended period after cataract surgery in eyes with and without pseudoexfoliation syndrome (PES). METHODS:Forty-six patients with PES who underwent cataract surgery in the Eye Department, Oslo University Hospital, in 2001 and 2002 were enrolled and compared...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2010.02012.x

    authors: Ostern AE,Drolsum L

    更新日期:2012-08-01 00:00:00

  • Toxic effects of melphalan, topotecan and carboplatin on retinal pigment epithelial cells.

    abstract:PURPOSE:Clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma has been reported. We, therefore, investigated the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE in a cell culture model. METHODS:The e...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12990

    authors: Süsskind D,Hagemann U,Schrader M,Januschowski K,Schnichels S,Aisenbrey S

    更新日期:2016-08-01 00:00:00

  • Mechanism and prognostic indicators for explosion-related eye trauma: eye injury vitrectomy study.

    abstract:PURPOSE:To explore the clinical features, surgical interventions and prognosis of injured eyes following explosion and to develop the risk factors for poor prognosis. METHODS:A nested case-control study. To the date of 31 December 2018, 99 explosion-related eye globes were selected from the Eye Injury Vitrectomy Study...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14713

    authors: Feng K,Yao Y,Wang ZJ,Nie HP,Pang XQ,Chen HJ,Jiang YR,Hu YT,Ma ZZ

    更新日期:2021-01-08 00:00:00

  • High-resolution ultrasound biomicroscopy as an adjunctive diagnostic tool for anterior scleral inflammatory disease.

    abstract:PURPOSE:To study high-resolution ultrasound biomicroscopy (UBM) findings in anterior scleral inflammatory disease and evaluate the efficacy of high-resolution UBM as an adjunctive diagnostic tool. METHODS:A cross-sectional study. The medical records of 30 patients (33 eyes) with episcleritis or anterior scleritis were...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12995

    authors: Zur D,Neudorfer M,Shulman S,Rosenblatt A,Habot-Wilner Z

    更新日期:2016-09-01 00:00:00

  • Bimonthly, treat-and-extend and as-needed ranibizumab in naïve neovascular age-related macular degeneration patients: 12-month outcomes of a randomized study.

    abstract:PURPOSE:To assess the noninferiority of the treat-and-extend (T&E) and fixed bimonthly regimens of 0.5 mg intravitreal ranibizumab as compared with the pro re nata (PRN) in naïve patients with neovascular age-related macular degeneration (nAMD). METHODS:Phase IV, randomized, 12-month, multicentre trial. Patients aged ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14399

    authors: López Gálvez MI,Arias Barquet L,S Figueroa M,García-Layana A,Ruiz Moreno JM,In-Eye Study Group.

    更新日期:2020-11-01 00:00:00

  • Early detection of type 2 diabetes mellitus and screening for retinopathy are associated with reduced prevalence and severity of retinopathy.

    abstract:PURPOSE:To explore whether the prevalence and severity of retinopathy differ in diabetes cohorts diagnosed through screening as compared with conventional health care. METHODS:A total of 257 diabetes patients, 151 detected through screening and 106 through conventional clinical care, were included. Retinopathy was eva...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12954

    authors: Olafsdottir E,Andersson DK,Dedorsson I,Svärdsudd K,Jansson SP,Stefánsson E

    更新日期:2016-05-01 00:00:00

  • Optimizing the treatment of rhegmatogenous retinal detachment.

    abstract::Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

    journal_title:Acta ophthalmologica

    pub_type: 历史文章,杂志文章

    doi:10.1111/aos.12991

    authors: Hajari JN

    更新日期:2016-03-01 00:00:00

  • Endoscopic dacryocystorhinostomy: long-term experience and outcomes.

    abstract:PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.13217

    authors: Coumou AD,Genders SW,Smid TM,Saeed P

    更新日期:2017-02-01 00:00:00

  • Perforin expression in eyelid sebaceous carcinomas: a useful and specific immunomarker for the differential diagnosis of eyelid carcinomas.

    abstract:PURPOSE:Eyelid sebaceous carcinoma (SC) remains a common diagnostic pitfall for both the clinician and histopathologist. The aim of this study was to describe perforin as a new marker in the immunohistochemistry panel for SC. METHODS:A total of 29 cases were retrieved from the Pathology archives, including 11 sebaceou...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12972

    authors: Mittal R,Araujo I,Czanner G,Coupland SE

    更新日期:2016-08-01 00:00:00

  • Physical activity and myopia in Danish children-The CHAMPS Eye Study.

    abstract:PURPOSE:To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS:This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.13513

    authors: Lundberg K,Suhr Thykjaer A,Søgaard Hansen R,Vestergaard AH,Jacobsen N,Goldschmidt E,Lima RA,Peto T,Wedderkopp N,Grauslund J

    更新日期:2018-03-01 00:00:00

  • Imbalances in tissue inhibitors of metalloproteinases differentiate choroidal neovascularization from geographic atrophy.

    abstract:PURPOSE:Tissue inhibitor of metalloproteinase (TIMP) is known to play a role in age-related macular degeneration (AMD). We wished to investigate alterations in different late stages of AMD: neovascular AMD and geographic atrophy (GA). METHODS:This was a prospective case-control study. A total of 125 participants were ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.13894

    authors: Krogh Nielsen M,Subhi Y,Rue Molbech C,Nilsson LL,Nissen MH,Sørensen TL

    更新日期:2019-02-01 00:00:00

  • Effects of multifocal soft contact lenses used to slow myopia progression on quality of vision in young adults.

    abstract:PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.13173

    authors: Kang P,McAlinden C,Wildsoet CF

    更新日期:2017-02-01 00:00:00

  • Children and young adults with anophthalmia and microphthalmia: Diagnosis and Management.

    abstract:PURPOSE:Congenital anophthalmia (A) and microphthalmia (M) are rare developmental defects, which could be isolated or syndromic. Our objective was to describe a cohort of children and young adults with A/M treated with ocular prosthesis, emphasizing clinical features, diagnosis, treatment, and follow-up. METHODS:Eight...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14427

    authors: Taha Najim R,Topa A,Jugård Y,Casslén B,Odersjö M,Andersson Grönlund M

    更新日期:2020-12-01 00:00:00

  • Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks: one year of follow-up.

    abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal bevacizumab at one year follow-up, for the treatment of choroidal neovascularization (CNV) associated with angioid streaks. METHODS:A retrospective case series of eighteen eyes of 17 patients with CNV secondary to angioid streaks treated with intravitreal bev...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2009.01836.x

    authors: El Matri L,Kort F,Bouraoui R,Karim B,Chebil A,Chaker N

    更新日期:2011-11-01 00:00:00

  • Exposure to antazoline-naphazoline eye drops during pregnancy and the risk of congenital malformations: a Danish nationwide cohort study.

    abstract:PURPOSE:To investigate whether exposure to antazoline-naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans. METHODS:All women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at le...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/aos.13980

    authors: Thomseth V,Cejvanovic V,Jimenez-Solem E,Poulsen HE,Utheim TP,Andersen JT

    更新日期:2019-08-01 00:00:00

  • Regulation of oxygen saturation in retinal blood vessels in response to dynamic exercise.

    abstract:PURPOSE:To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals. METHODS:Twenty-six healthy participants underwent moderate dynamic exercise (modified Master's two-step exercise). In all subjects, intraocular pressures (IOP), systolic and diastolic blood pressures (SBP and...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.13576

    authors: Heitmar R,Vekria P,Cubbidge RP

    更新日期:2018-05-01 00:00:00

  • Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration.

    abstract:PURPOSE:To provide a systematic review of the published studies pertaining to the lifestyle modification, dietary, nutritional and vitamins supplements for preventing occurrence or halting deterioration of age-related macular degeneration (AMD). METHODS:The literature searches from 1990 to December 2010 with following...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审

    doi:10.1111/j.1755-3768.2011.02357.x

    authors: Sin HP,Liu DT,Lam DS

    更新日期:2013-02-01 00:00:00

  • The Groningen Longitudinal Glaucoma Study. II. A prospective comparison of frequency doubling perimetry, the GDx nerve fibre analyser and standard automated perimetry in glaucoma suspect patients.

    abstract:PURPOSE:We aimed to determine prospectively the incidence of abnormal test results on frequency doubling perimetry (FDT), the nerve fibre analyser (GDx) and standard automated perimetry (SAP) in a cohort of glaucoma suspect patients with normal findings for all these tests at baseline. METHODS:Seventy glaucoma suspect...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2008.01279.x

    authors: Jansonius NM,Heeg GP

    更新日期:2009-06-01 00:00:00

  • Novel membrane frizzled-related protein gene mutation as cause of posterior microphthalmia resulting in high hyperopia with macular folds.

    abstract:PURPOSE:We present a genetic and clinical analysis of two sisters, 3 and 4 years of age, with nanophthalmos and macular folds. METHODS:Ophthalmological examination, general paediatric examination and molecular genetic analysis of the MFRP gene were performed in both affected siblings. RESULTS:Clinical analysis showed...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12105

    authors: Wasmann RA,Wassink-Ruiter JS,Sundin OH,Morales E,Verheij JB,Pott JW

    更新日期:2014-05-01 00:00:00

  • Design, synthesis and antiamoebic activity of dysprosium-based nanoparticles using contact lenses as carriers against Acanthamoeba sp.

    abstract:PURPOSE:Contact lenses have direct contact with the corneal surface and can induce sight-threatening infection of the cornea known as Acanthamoeba keratitis. The objective of this study was to evaluate the dysprosium-based nanoparticles (Dy-based NPs), namely Fe3 O4 -PEG-Dy2 O3 nanocomposites and Dy(OH)3 nanorods, as a...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14541

    authors: Kusrini E,Sabira K,Hashim F,Abdullah NA,Usman A,Putra N,Prasetyanto EA

    更新日期:2020-07-23 00:00:00

  • Prevalence and risk factors for angle-closure disease in a rural Northeast China population: a population-based survey in Bin County, Harbin.

    abstract:PURPOSE:To estimate the prevalence of primary angle-closure glaucoma (PACG), primary angle closure (PAC) and primary angle-closure suspect (PACS) and associated risk factors for PACG in a rural population in Northeast China. METHODS:A population-based survey was conducted in Bin County, Harbin, Northeast China. Glauco...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2011.02146.x

    authors: Qu W,Li Y,Song W,Zhou X,Kang Y,Yan L,Sui H,Yuan H

    更新日期:2011-09-01 00:00:00

  • Variability in short-wavelength automated perimetry among peri- or postmenopausal women: a dependence on phyto-oestrogen consumption?

    abstract:PURPOSE:To determine whether the hill of vision for Short-Wavelength Automated Perimetry (SWAP) is shallower for women who consume phyto-oestrogen-rich foods than for women who do not. METHODS:Visual field data were compared for two groups of healthy amenorrhoeic women 48-69 years-old with normal vision and not using ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2009.01799.x

    authors: Eisner A,Demirel S

    更新日期:2011-05-01 00:00:00

  • Difference in the posterior pole profiles associated with the initial location of visual field defect in early-stage normal tension glaucoma.

    abstract:PURPOSE:To identify the differences in posterior pole profiles between early normal tension glaucoma (NTG) patients with an initial central visual field (VF) loss and those with a peripheral VF loss. METHODS:Normal tension glaucoma patients with parafoveal scotoma (PFS; within a central 10° of fixation; superior, n=47...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.12492

    authors: Choi JA,Park HY,Park CK

    更新日期:2015-03-01 00:00:00

  • Subjective visual sensations during cataract surgery performed under topical anaesthesia.

    abstract:PURPOSE:To examine the patient's subjective visual sensations during cataract surgery performed under topical anaesthesia. METHODS:Prospective, non-randomized, cohort study. One hundred and thirty-two patients were interviewed by standard questionnaire within 1 hr of uncomplicated cataract surgery performed under topi...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/j.1755-3768.2007.01153.x

    authors: Biró Z,Schvöller M

    更新日期:2008-12-01 00:00:00

  • Effect of glaucoma drainage implant surgery on corneal topography: a prospective study.

    abstract:PURPOSE:To study the effect of glaucoma drainage implant (GDI) surgery on corneal topography during the first postoperative year. METHODS:Twenty-one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 GDI. Corneal topography measurements were taken preoperatively and at 6 and 12 months after surg...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14247

    authors: Koivusalo R,Välimäki J

    更新日期:2020-05-01 00:00:00

  • The impact of light source on discrimination ability in subjects with age-related macular degeneration.

    abstract:PURPOSE:To examine the influence of light source on letter contrast sensitivity in subjects with age-related macular degeneration (AMD). METHODS:Halogen incandescent bulbs and low-energy fluorescent tubes were tested with 70 subjects with AMD. The subjects' contrast sensitivity was determined in a randomized single-bl...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1755-3768.2009.01809.x

    authors: Holton H,Christiansen AB,Albeck MJ,Johnsen CR

    更新日期:2011-12-01 00:00:00

  • Phacotrabeculectomy using collagen matrix implant (Ologen® ) versus mitomycin C: a prospective randomized controlled trial.

    abstract:PURPOSE:To compare the efficacy and safety of collagen matrix implant (Ologen® ; OLO) with mitomycin C (MMC) in phacotrabeculectomy. METHODS:Prospective, single-centre, nonblinded, randomized controlled trial. A total of 53 eyes of 45 patients were enrolled in the study protocol with 27 eyes randomly assigned to OLO a...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/aos.14102

    authors: Wlaź A,Wilkos-Kuc A,Rozegnał-Madej A,Żarnowski T

    更新日期:2019-09-01 00:00:00

  • Full-field electroretinography in age-related macular degeneration: an overall retinal response.

    abstract:PURPOSE:Age-related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full-field electroretinography (ffERG) measures an electrical response, not...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章

    doi:10.1111/aos.14571

    authors: Forshaw TRJ,Kjaer TW,Andréasson S,Sørensen TL

    更新日期:2020-08-24 00:00:00

  • Reducing avoidable visual impairment in elderly home healthcare patients by basic ophthalmologic screening.

    abstract:PURPOSE:To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS:Cross-sectional stu...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究

    doi:10.1111/aos.13956

    authors: van Nispen R,van der Aa H,Timmermans F,Meijer N,Koster N,de Blok J,Keunen J,van Rens G

    更新日期:2019-06-01 00:00:00