Perforin expression in eyelid sebaceous carcinomas: a useful and specific immunomarker for the differential diagnosis of eyelid carcinomas.

abstract：PURPOSE:To investigate the relationship between time spent outdoors, at particular ages in childhood and adolescence, and myopia status in young adulthood using serum 25-hydroxyvitamin D [25(OH)D] concentration as a biomarker of time spent outdoors. METHODS:Participants of the Raine Study Generation 2 cohort had 25(OH...

journal_title：Acta ophthalmologica

authors： Lingham G,Mackey DA,Zhu K,Lucas RM,Black LJ,Oddy WH,Holt P,Walsh JP,Sanfilippo PG,Chan She Ping-Delfos W,Yazar S

更新日期：2021-01-10 00:00:00

abstract：PURPOSE:Enzyme replacement therapy (ERT) was offered from year 2001 to patients with Fabry disease. The ophthalmic experience was analysed, as part of a general 10-year status. METHODS:A retrospective observational series comprising 39 patients (25 females, 14 males) closely followed by the endocrinologists, and with ...

journal_title：Acta ophthalmologica

authors： Fledelius HC,Sandfeld L,Rasmussen ÅK,Madsen CV,Feldt-Rasmussen U

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To report normative data on visual acuity (VA) for near and distance, refraction, ocular alignment, ocular motility and stereo acuity in a cohort of children aged 4.5-7 years. METHODS:A total of 950 children with normal development from the municipality of Roskilde, Denmark, were invited to participate in an o...

journal_title：Acta ophthalmologica

authors： Sandfeld L,Weihrauch H,Tubaek G,Mortzos P

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to analyse 69 Chinese patients with USH2A mutations and to assess the genotype-phenotype correlation. METHODS:All 36 Usher syndrome type IIA patients and 33 nonsyndromic RP (retinitis pigmentosa) patients underwent clinical examinations. Eye examinations included best-corrected visual...

journal_title：Acta ophthalmologica

authors： Meng X,Liu X,Li Y,Guo T,Yang L

更新日期：2020-10-29 00:00:00

abstract：PURPOSE:To examine the influence of light source on letter contrast sensitivity in subjects with age-related macular degeneration (AMD). METHODS:Halogen incandescent bulbs and low-energy fluorescent tubes were tested with 70 subjects with AMD. The subjects' contrast sensitivity was determined in a randomized single-bl...

journal_title：Acta ophthalmologica

authors： Holton H,Christiansen AB,Albeck MJ,Johnsen CR

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To explore associations of lamina cribrosa thickness with axial length and thickness of the posterior sclera in monkeys. METHODS:Examining histological sections by light microscopy, we measured the thickness of the lamina cribrosa and posterior sclera and axial length. RESULTS:The study included 28 animals (2...

journal_title：Acta ophthalmologica

authors： Jonas JB,Kutscher JN,Panda-Jonas S,Hayreh SS

更新日期：2016-12-01 00:00:00

abstract：:To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refra...

journal_title：Acta ophthalmologica

authors： García-Montero M,Albarrán Diego C,Garzón-Jiménez N,Pérez-Cambrodí RJ,López-Artero E,Ondategui-Parra JC

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Photodynamic riboflavin/ultraviolet-A (UVA)-induced collagen cross-linking, which increases the biomechanical stiffness of the human cornea by about 300%, has been introduced recently as a possible treatment for progressive keratoconus. The present study was undertaken to evaluate the longterm biomechanical eff...

journal_title：Acta ophthalmologica

authors： Wollensak G,Iomdina E

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To investigate the incidence and cause of severe visual loss following use and removal of intraocular silicone oil (SiO) after uncomplicated vitrectomy and SiO injection for primary rhegmatogenous retinal detachment (RRD). METHODS:Consecutive case series of 216 patients operated with vitrectomy for primary RRD...

journal_title：Acta ophthalmologica

authors： Christensen UC,la Cour M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To investigate the ability of mesenchymal stem cells (MSC) to transdifferentiate to corneal epithelial cells in experimental limbal stem cell deficiency in rabbits. METHODS:Total limbal stem cell deficiency was produced in 21 right eyes of 21 New Zealand rabbits; 6 eyes served as controls (group 1, G1). After ...

journal_title：Acta ophthalmologica

authors： Reinshagen H,Auw-Haedrich C,Sorg RV,Boehringer D,Eberwein P,Schwartzkopff J,Sundmacher R,Reinhard T

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

journal_title：Acta ophthalmologica

authors： van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...

journal_title：Acta ophthalmologica

authors： Murakami Y,Ikeda Y,Nakatake S,Fujiwara K,Tachibana T,Yoshida N,Notomi S,Hisatomi T,Yoshida S,Ishibashi T,Sonoda KH

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:This paper reviews current knowledge about the pathogenesis, clinical manifestations and treatment of lattice corneal dystrophy, gelsolin type (LCD2, Meretoja's syndrome). METHODS:Material is derived from literature searches, a case study of a Finnish patient living in Sweden, and interviews in Helsinki with P...

journal_title：Acta ophthalmologica

authors： Carrwik C,Stenevi U

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To assess the association between exogenous oestrogen exposure, female reproductive factors and the long-term incidence of cataract. METHODS:People aged 49+ years living in a defined geographic region were invited to participate in this prospective population-based survey. Of 2072 women (83% of those eligible)...

journal_title：Acta ophthalmologica

authors： Kanthan GL,Wang JJ,Burlutsky G,Rochtchina E,Cumming RG,Mitchell P

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To investigate serial changes in the bleb wall using anterior segment optical coherence tomography (AS-OCT) in patients who had undergone Ahmed glaucoma valve (AGV) implantation. METHODS:A total of 52 patients who had undergone AGV implantation were enrolled. Reflectivity and mean thickness of the bleb wall we...

journal_title：Acta ophthalmologica

authors： Jung KI,Park H,Jung Y,Park CK

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:Posterior capsule opacification (PCO) occurs as a common complication after cataract surgery. Erlotinib is an inhibitor of the epidermal growth factor-Receptor and reduces critical cellular events leading to PCO. In this in vitro study, Erlotinib-modified intraocular lenses (IOLs) employed as a drug delivery de...

journal_title：Acta ophthalmologica

authors： Wertheimer C,Kueres A,Siedlecki J,Braun C,Kassumeh S,Wolf A,Mayer W,Priglinger C,Priglinger S,Eibl-Lindner K

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...

journal_title：Acta ophthalmologica

authors： Loukovaara S,Haukka J

更新日期：2021-01-02 00:00:00

abstract：:Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

journal_title：Acta ophthalmologica

authors： Hajari JN

更新日期：2016-03-01 00:00:00

abstract：:Although the work for which Emil von Behring (1854-1917) was awarded the first Nobel Prize Winner for Medicine or Physiology in 1901 was on serum therapy, not only was he trained and worked as an ophthalmologist but he also wrote his doctoral dissertation on a practical ophthalmological topic whilst in Berlin under Ca...

journal_title：Acta ophthalmologica

authors： Grzybowski A,Wilhelm H

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To assess the postoperative stability of three-piece intraocular lens (IOL) implants using ultrasound biomicroscopy (UBM). METHODS:This is a prospective observational cohort case series. Best-corrected visual acuity (BCVA) assessment, slit lamp examination, refraction and UBM evaluation were performed preopera...

journal_title：Acta ophthalmologica

authors： Ang GS,Duncan L,Atta HR

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To evaluate microperimetric changes 1year after macular hole surgery with triamcinolone acetonide assisted internal limiting membrane (ILM) peeling. METHODS:Twenty-two eyes of 22 patients with stage 3 and 4 idiopathic macular holes of <6months' duration underwent vitrectomy with triamcinolone acetonide assiste...

journal_title：Acta ophthalmologica

authors： Ozdemir H,Karacorlu M,Senturk F,Karacorlu SA,Uysal O

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate the ability of ultrasound biomicroscopy (UBM) to detect abnormalities in the zonular apparatus in unaffected eyes of patients with clinically unilateral exfoliation syndrome (XFS) using a standardized grading system. METHODS:The affected and unaffected eyes of 17 patients with clinically unilateral...

journal_title：Acta ophthalmologica

authors： Sbeity Z,Dorairaj SK,Reddy S,Tello C,Liebmann JM,Ritch R

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:The Gloucestershire Diabetic Eye Screening Programme offers annual digital photographic screening for diabetic retinopathy to a countywide population of people with diabetes. This study was designed to investigate progression of diabetic retinopathy in this programme of the English NHS Diabetic Eye Screening Pr...

journal_title：Acta ophthalmologica

authors： Scanlon PH,Stratton IM,Histed M,Chave SJ,Aldington SJ

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). METHODS:Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS...

journal_title：Acta ophthalmologica

authors： Krarup T,Holm LM,la Cour M,Kjaerbo H

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To examine the public health impact of presbyopia regarding its effect on quality of life (QoL) and society in both the developed and developing worlds. METHODS:A database was created from articles found on PubMed, the Cochrane Library and Science Direct using the following search terms: presbyopia, QoL, accom...

journal_title：Acta ophthalmologica

authors： Goertz AD,Stewart WC,Burns WR,Stewart JA,Nelson LA

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To describe the clinical phenotype and the molecular pathology in a group of patients with congenital stationary night blindness due to mutations in GRM6, a gene encoding the ON bipolar metabotropic glutamate receptor 6 (mGluR6). METHODS:Nine patients from seven families (age range, 7-75; median, 10 years) wit...

journal_title：Acta ophthalmologica

authors： Sergouniotis PI,Robson AG,Li Z,Devery S,Holder GE,Moore AT,Webster AR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...

journal_title：Acta ophthalmologica

authors： Prokosch V,Brockhaus K,Anders F,Liu H,Mercieca K,Gericke A,Melkonyan H,Thanos S

更新日期：2019-12-29 00:00:00

abstract：PURPOSE:To evaluate the influence of haemorheopheresis on anatomical and functional findings in patients with soft-drusen maculopathy. METHODS:We investigated 29 eyes (16 patients) and randomized 25 eyes (16 controls) with soft-drusen maculopathy [soft, confluent and reticular drusen, drusenoid retinal pigment epithel...

journal_title：Acta ophthalmologica

authors： Rencová E,Bláha M,Studnička J,Blažek M,Bláha V,Dusová J,Malý J,Kyprianou G,Vašátko T,Langrová H

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical ...

journal_title：Acta ophthalmologica

authors： Gerendas BS,Kroisamer JS,Buehl W,Rezar-Dreindl SM,Eibenberger KM,Pablik E,Schmidt-Erfurth U,Sacu S

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of big-bubble (BB) technique in separating Dua's layer together with the Descemet's membrane endothelial (DE) graft and the effect of 7-day storage of the prepared tissues on the endothelial cells. METHOD:This is an experimental study in which 21 human corneo-scleral tissues unsuitable...

journal_title：Acta ophthalmologica

authors： GamalElDin SA,Salama MM,ElShazly MI

更新日期：2016-03-01 00:00:00