Abstract：
PURPOSE:To explore associations of lamina cribrosa thickness with axial length and thickness of the posterior sclera in monkeys. METHODS:Examining histological sections by light microscopy, we measured the thickness of the lamina cribrosa and posterior sclera and axial length. RESULTS:The study included 28 animals (28 eyes) with a mean age of 13.3 ± 4.9 years (range: 3-24 years) and mean axial length of 18.9 ± 1.4 mm (range: 17-21 mm) (22 eyes after experimental temporary central retinal artery occlusion; four eyes after a permanent occlusion of the posterior ciliary artery; and two eyes without any intervention). Mean thickness of the lamina cribrosa was 167 ± 30 μm (range: 115-273 μm). Thinner lamina cribrosa thickness was significantly associated with longer axial length (standardized correlation coefficient beta: -0.42; p = 0.026), with thinner sclera at the posterior pole (beta: 0.56; p = 0.002) and with thinner sclera at the disc border (beta: 0.55; p = 0.002). Lamina cribrosa thickness was not significantly related to temporary central retinal artery occlusion (p = 0.14) or to permanent posterior ciliary artery occlusion (p = 0.49) or age (p = 0.46). CONCLUSIONS:As in humans, lamina cribrosa thickness in non-glaucomatous monkeys got thinner with longer axial length and with thinner posterior sclera. These data may be of interest for studies on the process of emmetropization/myopization in monkeys, and they may be of interest for the studies on the biomechanics of the optic nerve head.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Jonas JB,Kutscher JN,Panda-Jonas S,Hayreh SSdoi
10.1111/aos.13070subject
Has Abstractpub_date
2016-12-01 00:00:00pages
e693-e696issue
8eissn
1755-375Xissn
1755-3768journal_volume
94pub_type
杂志文章abstract：PURPOSE:To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals. METHODS:Twenty-six healthy participants underwent moderate dynamic exercise (modified Master's two-step exercise). In all subjects, intraocular pressures (IOP), systolic and diastolic blood pressures (SBP and...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13576
更新日期：2018-05-01 00:00:00
abstract：:Topically applied carbonic anhydrase inhibitors (CAIs) in eye drop solutions are commonly used to treat glaucoma. However, local eye irritation and multiple daily administrations may hamper their clinical usefulness. Aqueous eye drop formulations that improve their topical bioavailability and reduce their eye irritati...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/j.1755-3768.2011.02299.x
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:This study aimed to investigate the retinal thickness analyser (RTA) as a means to identify the presence of cystoid macular oedema (CMO) in children with uveitis, whether the course of CMO can be monitored using this method, and whether there is a trend towards a correlation between macular oedema and visual ac...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1600-0420.2007.01009.x
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To test the expanded polytetrafluoroethylene (ePTFE) as a new adjuvant in trabeculectomy. METHODS:Consecutive glaucoma surgical inpatients were observed at the Department of Ophthalmology of Palermo University. Sixty patients (60 eyes) were randomly assigned to undergo trabeculectomy (T), trabeculectomy with m...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0420.2007.01036.x
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To report the accuracy of intraocular lens (IOL) power estimation in eyes that have undergone phacovitrectomy for retinal diseases with accompanying macular oedema. METHODS:A retrospective study was conducted in 23 eyes of 23 patients at Soonchunhyang University Hospital, Seoul, Korea. The relationship between...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01752.x
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:Ocular and brain microcirculation share embryological and histological similarities. The retinal vascular fractal dimension (FD) is a marker of retinal vascular complexity of the vascular tree. The purpose of this study was to explore the relationship between cerebral blood flow (CBF), retinal vascular FD and o...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14232
更新日期：2020-02-01 00:00:00
abstract：AIMS:This prospective, multicenter, single-masked study evaluated the additive effect of dorzolamide hydrochloride 2% on the diurnal intraocular pressure (IOP) curve and retinal and retrobulbar hemodynamics in patients with primary open-angle glaucoma (POAG) treated with morning-dosed bimatoprost 0.03%. METHODS:Eighty...
journal_title：Acta ophthalmologica
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1755-3768.2010.02036.x
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:To assess the predictive value of optical coherence tomography (OCT) mapping of retinal thickness and intraretinal morphological changes after macular grid for diffuse diabetic macular oedema (DMO). METHODS:We carried out a prospective, non-controlled, case series study, in which 28 consecutive eyes with previ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1600-0420.2007.01048.x
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). METHODS:Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS...
journal_title：Acta ophthalmologica
pub_type： 临床试验,杂志文章
doi：10.1111/aos.12406
更新日期：2014-11-01 00:00:00
abstract：:This literature review is aimed at the evaluation of the potential for cataract prevention in Europe. It was performed using PubMed with Mesh and free-text terms. Studies included were (i) performed on a population of Caucasian origin at an age range of 40-95 years, (ii) cataract was clinically verified, (iii) drug re...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/j.1755-3768.2012.02444.x
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:To investigate the value of posterior keratometry in the assessment of surgically induced astigmatic change (AC) in cataract surgery, with particular emphasis on the influence of test-retest variability. METHODS:Seventy-seven eyes of 77 cataract patients scheduled for routine cataract surgery were enrolled. Al...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13003
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12093
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:Limited knowledge exists about the influence of donor age and death-to-preservation interval (DPI) on the metabolic properties of the cornea. The aim of this study is to investigate the relationship between both factors and metabolite content of the cornea. METHODS:Corneas from 15 human donors (age: 41-78 year...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2011.02271.x
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14717
更新日期：2021-01-02 00:00:00
abstract：PURPOSE:To establish whether or not the dynamics of saccadic eye movements are significantly changed in patients with different stages of thyroid-associated ophthalmopathy (TAO) and, subsequently, if analysis of saccades could serve as an additional diagnostic tool for early detection of inflammatory activity in TAO. ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2011.02216.x
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS:Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS e...
journal_title：Acta ophthalmologica
pub_type：
doi：10.1111/aos.13950
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:To characterize pre- and perioperative factors associated with treatment for wet age-related macular degeneration (wet AMD) after cataract surgery. METHODS:This register-based cohort study with data from the Swedish National Cataract Register (NCR) and the Swedish Macula Register (SMR) from 2010 to 2017 compar...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14519
更新日期：2020-06-23 00:00:00
abstract：PURPOSE:The purpose of this study was to establish a standardized in vitro phacoemulsification damage model for future investigations of the effects of phacoemulsification, surgical devices, protective ophthalmic viscoelastic devices (OVDs), irrigation solutions and other aspects related to cataract phacoemulsification...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14235
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To examine visual acuity, refraction and ocular status before, during and after hyperbaric oxygen therapy (HBOT). METHODS:Twenty-nine patients underwent 40 standard protocol HBOT treatments. In all subjects, refraction and best corrected visual acuity were measured at baseline and after ten, 20, 30 and 40 trea...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14010
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To investigate the distribution of intraocular pressure (IOP) measured by Goldmann applanation tonometry (GAT) and factors correlating with IOP, with special attention to age, in a large sample of ophthalmologically normal Japanese subjects. METHODS:A total of 7313 subjects (2847 male, 4466 female) were select...
journal_title：Acta ophthalmologica
pub_type： 临床试验,杂志文章
doi：10.1111/j.1600-0420.2007.01068.x
更新日期：2008-06-01 00:00:00
abstract：:In the context of the COVID-19 pandemic, this paper provides recommendations for medical eye care during the easing of control measures after lockdown. The guidelines presented are based on a literature review and consensus among all Spanish Ophthalmology Societies regarding protection measures recommended for the oph...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,评审
doi：10.1111/aos.14752
更新日期：2021-01-12 00:00:00
abstract：PURPOSE:A recent threefold increase in laser treatment for advanced retinopathy of prematurity (ROP) triggered a nationwide preschool ophthalmic and developmental status among extremely preterm survivors. Here, we discuss refraction and visual acuity. METHODS:Survivors (n = 178) from a national birth cohort (February ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12643
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To explore whether the prevalence and severity of retinopathy differ in diabetes cohorts diagnosed through screening as compared with conventional health care. METHODS:A total of 257 diabetes patients, 151 detected through screening and 106 through conventional clinical care, were included. Retinopathy was eva...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.12954
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To evaluate association of the van Herick (VH) grades with the ultrasound biomicroscopic (UBM) parameters, appositional irido-trabecular contact (A-ITC) and plateau iris (PI) in a randomly sampled population. METHODS:A 10% random sample of all residents aged 40 or older of the Kumejima study underwent UBM unde...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.14502
更新日期：2020-06-22 00:00:00
abstract：PURPOSE:As some surgical procedures have been shown to increase postoperative flare values and thus contribute to blood-ocular barrier breakdown, retinal reattachment surgery might influence the risk of developing proliferative vitreoretinopathy (PVR). Therefore, we investigated whether postoperative aqueous flare valu...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/aos.13560
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND/AIMS:The mitotic count of uveal melanomas correlates with the risk of metastatic death, but with haematoxylin and eosin (H&E)-stained sections, it can be difficult to identify mitotic figures (MF) reliably. We investigated whether this measurement could be enhanced by immunohistochemistry, using the mitosis-...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01769.x
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:To examine preoperative anti-inflammatory treatment on recovery from cataract surgery in eyes of diabetic patients. METHODS:A Prospective randomized clinical trial. One hundred and three eyes of 103 patients with diabetes undergoing routine cataract surgery were randomized (1:1) not to receive any preoperative...
journal_title：Acta ophthalmologica
pub_type： 杂志文章,随机对照试验
doi：10.1111/aos.14018
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:The Pyhäjärvi Cataract Study aims to study demand for cataract surgery in the population of a rural town in Finland. METHODS:A random, population-based sample of 881 persons aged > or = 60 years were interviewed by telephone to obtain a Visual Function-14 (VF-14) score. A total of 294 persons were invited for ...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1600-0420.2007.01118.x
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2010.01997.x
更新日期：2010-11-01 00:00:00
abstract：PURPOSE: To evaluate central corneal thickness (CCT), intraocular pressure (IOP) and eye refraction in patients with congenital growth hormone (GH) deficiency. METHODS:Retrospective case series. Forty-five patients with growth defect treated with recombinant GH and 45 healthy children underwent ophthalmological exami...
journal_title：Acta ophthalmologica
pub_type： 杂志文章
doi：10.1111/j.1755-3768.2009.01519.x
更新日期：2010-09-01 00:00:00
