Abstract:
PURPOSE:To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS:Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS eyes, seven fellow eyes) and 12 control subjects. The diagnosis of OIS was supported by carotid artery Doppler ultrasonography and pneumoplethysmographic measurement of ocular systolic perfusion pressure. RESULTS:Macular arterial blood flow velocity (median, range) was 1.8 (1.4-2.7) mm/s in OIS eyes, 4.0 (2.9-5.3) mm/s in fellow eyes (p = 0.016) and 3.8 (2.3-5.1) mm/s in control eyes (p = 0.0004 and p = 0.67 versus OIS and fellow eyes, respectively). Macular venous blood flow velocity was 1.5 (1.0-2.1) mm/s in OIS eyes, 2.6 (2.0-2.9) mm/s in fellow eyes (p = 0.016) and 2.7 (1.8-3.5) mm/s in control eyes (p = 0.0007 and p = 0.64). Arterial velocities were below or equal to the lowest value observed in control subjects (≤2.3 mm/s) in seven of eight eyes with OIS. Visual acuity 0.7 or worse was found in two OIS eyes with arterial velocities below 1.7 mm/s and venous velocities below 1.3 mm/s and together with neovascular glaucoma or polycythemia vera (one eye each). CONCLUSION:Motion-contrast imaging revealed markedly reduced macular perfusion velocities in OIS eyes compared with unaffected fellow eyes and healthy control eyes. The method appears to provide a clinically meaningful quantitative measure of macular hypoperfusion.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Klefter ON,Kofoed PK,Munch IC,Larsen Mdoi
10.1111/aos.13950subject
Has Abstractpub_date
2019-02-01 00:00:00pages
113-117issue
1eissn
1755-375Xissn
1755-3768journal_volume
97pub_type
abstract:PURPOSE:To study the intraocular pressure (IOP)-reducing effect of deep sclerectomy on normal-tension glaucoma (NTG) patients. METHODS:We retrospectively analysed 21 eyes of 18 consecutive NTG patients who had undergone deep sclerectomy with mitomycin-C and a collagen implant. RESULTS:Median (range) preoperative IOP ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01623.x
更新日期:2010-02-01 00:00:00
abstract::Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...
journal_title:Acta ophthalmologica
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更新日期:2020-11-16 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01752.x
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2020-06-23 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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更新日期:2014-08-01 00:00:00
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journal_title:Acta ophthalmologica
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更新日期:2020-02-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02248.x
更新日期:2012-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13665
更新日期:2018-11-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01812.x
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pub_type: 杂志文章,评审
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更新日期:2013-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
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更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-12-01 00:00:00
abstract::Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...
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pub_type: 杂志文章,评审
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更新日期:2015-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-01-24 00:00:00
abstract::Data on the association between hypothyroidism and glaucoma are conflicting. We sought to shed light on this by conducting a critical review and meta-analyses. The meta-analyses were conducted in adherence with the widely accepted MOOSE guidelines. Using the Medical Subject Heading (MeSH) terms: hypothyroidism, myxoed...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13464
更新日期:2017-11-01 00:00:00
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更新日期:2017-09-01 00:00:00