Abstract:
PURPOSE:To investigate the reproducibility of Bruch's membrane opening minimum rim width (BMO-MRW) and retinal nerve fibre layer thickness (RNFLT) measurements using spectral domain optical coherence tomography (SD-OCT). Additionally, to investigate the reproducibility of BMO area measurements and fovea to BMO centre (FoBMO) angle. METHODS:Participants were healthy subjects (n = 30) and patients with glaucoma (n = 26). One eye of each participant was scanned to obtain optic nerve head (24 radial B-scans) and peripapillary (one circular B-scan) images by three independent examiners. Additionally, one examiner imaged each participant three times on the same day. Intra- and interobserver reproducibilities were estimated by within-subject standard deviation (SW) and coefficient of variation (COV). Spearman's rank correlation coefficient was used to test the correlation between the magnitude of the parameter and its standard deviation. RESULTS:The global BMO-MRW COVs (%) in healthy/glaucoma subjects were 0.87/1.34 and 1.28/3.13 for intra- and interobserver analyses, respectively, and the corresponding global RNFLT figures were 1.50/2.10 and 2.04/2.87. Global mean BMO-MRW and RNFLT showed no correlation with their respective standard deviations. The reproducibilities of BMO area and FoBMO angle were excellent and similar between the groups. CONCLUSION:The reproducibilities of BMO-MRW, BMO area measurements and FoBMO angle were excellent in both healthy subjects and patients with glaucoma. Bruch's membrane opening minimum rim width (BMO-MRW) reproducibility is comparable to that of RNFLT measurements.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Reis ASC,Zangalli CES,Abe RY,Silva AL,Vianna JR,Vasconcellos JPC,Costa VPdoi
10.1111/aos.13464subject
Has Abstractpub_date
2017-11-01 00:00:00pages
e548-e555issue
7eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
杂志文章abstract:PURPOSE:To study healing of retinal laser lesions in patients undergoing PRP using SD-OCT. METHODS:Moderate, light and barely visible retinal burns were produced in patients with proliferative diabetic retinopathy scheduled for PRP using 100-, 20- and 10-ms pulses of 532-nm laser, with retinal spot sizes of 100, 200 a...
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更新日期:2018-03-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2020-03-01 00:00:00
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