Impact of visceral fat and pro-inflammatory factors on the pathogenesis of age-related macular degeneration.

abstract：PURPOSE:To compare pars plana vitrectomy and 360° endolaser therapy with pars plana vitrectomy and an encircling scleral buckle for the treatment of primary rhegmatogenous retinal detachments in a randomized pilot study including 60 patients. METHODS:Main outcome measures were single-surgery anatomic success rate and ...

journal_title：Acta ophthalmologica

authors： Falkner-Radler CI,Graf A,Binder S

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...

journal_title：Acta ophthalmologica

authors： Bonnin P,Pournaras JA,Lazrak Z,Cohen SY,Legargasson JF,Gaudric A,Levy BI,Massin P

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To assess the condition of the corneal endothelium an extended period after cataract surgery in eyes with and without pseudoexfoliation syndrome (PES). METHODS:Forty-six patients with PES who underwent cataract surgery in the Eye Department, Oslo University Hospital, in 2001 and 2002 were enrolled and compared...

journal_title：Acta ophthalmologica

authors： Ostern AE,Drolsum L

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS:Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn...

journal_title：Acta ophthalmologica

authors： Bacci GM,Donati MA,Pasquini E,Munier F,Cavicchi C,Morrone A,Sodi A,Murro V,Garcia Segarra N,Defilippi C,Bussolin L,Caputo R

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:As some surgical procedures have been shown to increase postoperative flare values and thus contribute to blood-ocular barrier breakdown, retinal reattachment surgery might influence the risk of developing proliferative vitreoretinopathy (PVR). Therefore, we investigated whether postoperative aqueous flare valu...

journal_title：Acta ophthalmologica

authors： Mulder VC,van Dijk EHC,van Meurs IA,La Heij EC,van Meurs JC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To examine visual acuity, refraction and ocular status before, during and after hyperbaric oxygen therapy (HBOT). METHODS:Twenty-nine patients underwent 40 standard protocol HBOT treatments. In all subjects, refraction and best corrected visual acuity were measured at baseline and after ten, 20, 30 and 40 trea...

journal_title：Acta ophthalmologica

authors： Riedl P,Škiljić D,Arnell P,Wannholt R,Zetterberg M,Andersson Grönlund M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To investigate risk factors for the development of the hypertensive phase after implantation of the Ahmed glaucoma valve (AGV). METHODS:A total of 128 patients who had undergone AGV implantation were included in this study. The hypertensive phase was defined as intraocular pressure (IOP) > 21 mmHg during the f...

journal_title：Acta ophthalmologica

authors： Jung KI,Park CK

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To investigate the associations between ocular pulse amplitude (OPA) as measured by dynamic contour tonometry (DCT) and ocular and systemic factors in patients with open angle glaucoma (OAG) and in glaucoma suspects. METHODS:One hundred and seventy-three glaucoma-suspect patients were consecutively enrolled. A...

journal_title：Acta ophthalmologica

authors： Choi J,Lee J,Park SB,Lee KS,Sung KR,Kook MS

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To investigate whether introduction of item-response theory (IRT) analysis, in parallel to the 'traditional' statistical analysis methods available for performance evaluation of multiple T/F items as used in the European Board of Ophthalmology Diploma (EBOD) examination, has proved beneficial, and secondly, to ...

journal_title：Acta ophthalmologica

authors： Mathysen DG,Aclimandos W,Roelant E,Wouters K,Creuzot-Garcher C,Ringens PJ,Hawlina M,Tassignon MJ

更新日期：2013-11-01 00:00:00

abstract：:A growing number of studies have reported a link between vascular damage and glaucoma based on optical coherence tomography angiography (OCTA) imaging. This multitude of studies focused on different regions of interest (ROIs) which offers the possibility to draw conclusions on the most discriminative locations to diag...

journal_title：Acta ophthalmologica

authors： Bekkers A,Borren N,Ederveen V,Fokkinga E,Andrade De Jesus D,Sánchez Brea L,Klein S,van Walsum T,Barbosa-Breda J,Stalmans I

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To evaluate the influence of haemorheopheresis on anatomical and functional findings in patients with soft-drusen maculopathy. METHODS:We investigated 29 eyes (16 patients) and randomized 25 eyes (16 controls) with soft-drusen maculopathy [soft, confluent and reticular drusen, drusenoid retinal pigment epithel...

journal_title：Acta ophthalmologica

authors： Rencová E,Bláha M,Studnička J,Blažek M,Bláha V,Dusová J,Malý J,Kyprianou G,Vašátko T,Langrová H

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to analyse 69 Chinese patients with USH2A mutations and to assess the genotype-phenotype correlation. METHODS:All 36 Usher syndrome type IIA patients and 33 nonsyndromic RP (retinitis pigmentosa) patients underwent clinical examinations. Eye examinations included best-corrected visual...

journal_title：Acta ophthalmologica

authors： Meng X,Liu X,Li Y,Guo T,Yang L

更新日期：2020-10-29 00:00:00

abstract：PURPOSE:To establish whether or not the dynamics of saccadic eye movements are significantly changed in patients with different stages of thyroid-associated ophthalmopathy (TAO) and, subsequently, if analysis of saccades could serve as an additional diagnostic tool for early detection of inflammatory activity in TAO. ...

journal_title：Acta ophthalmologica

authors： Schworm HD,Bolzani R,Benassi M,Tallstedt L,Rydberg A,Lennerstrand G,Ygge J

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:This study aimed to investigate intraocular pressure (IOP) measurements taken using the dynamic contour tonometer (DCT) and the non-contact tonometer (NCT) in subjects with keratoconus. METHODS:Intraocular pressure was measured in 20 keratoconus subjects and 20 age-matched control subjects using the DCT and NC...

journal_title：Acta ophthalmologica

authors： Read SA,Collins MJ

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To examine the correlation between health-related quality of life (HRQOL) scores [assessed using the generic Short Form Health Survey (SF-36) questionnaire] and vision-related quality of life (VRQOL) scores [assessed using the National Eye Institute Visual Function Questionnaire (NEI-VFQ25)]. METHODS:Cross-sec...

journal_title：Acta ophthalmologica

authors： Swamy BN,Chia EM,Wang JJ,Rochtchina E,Mitchell P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:Ocular and brain microcirculation share embryological and histological similarities. The retinal vascular fractal dimension (FD) is a marker of retinal vascular complexity of the vascular tree. The purpose of this study was to explore the relationship between cerebral blood flow (CBF), retinal vascular FD and o...

journal_title：Acta ophthalmologica

authors： Nadal J,Deverdun J,de Champfleur NM,Carriere I,Creuzot-Garcher C,Delcourt C,Chiquet C,Kawasaki R,Villain M,Ritchie K,Le Bars E,Daien V

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To determine (i) whether, compared to controls, visual complaints of glaucoma patients are more pronounced under extreme luminance conditions than in the optimal luminance condition and (ii) whether complaints belonging to different extreme luminance conditions are associated. METHODS:We developed a luminance-...

journal_title：Acta ophthalmologica

authors： Bierings RAJM,van Sonderen FLP,Jansonius NM

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:We set out to quantify changes in the anterior chamber volume (ACV), anterior chamber depth (ACD) and anterior chamber angle (ACA) measurements obtained by the Pentacam rotating Scheimpflug camera following uneventful phacoemulsification surgery in normotensive eyes with open iridocorneal angles. METHODS:We en...

journal_title：Acta ophthalmologica

authors： Uçakhan OO,Ozkan M,Kanpolat A

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:To compare the outcomes of microcatheter-assisted circumferential trabeculotomy to standard rigid probe trabeculotomy in childhood glaucomas. METHODS:Eyes of children requiring trabeculotomy for primary congenital or secondary paediatric glaucoma were randomized to undergo either trabeculotomy using the Glauco...

journal_title：Acta ophthalmologica

authors： El Sayed Y,Gawdat G

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To report complications after the implantation of intrastromal corneal ring segments (Keraring; Mediphacos, Belo Horizonte, Brazil) in keratoconic eyes using a femtosecond laser (IntraLase; Advanced Medical Optics, Santa Ana, California, USA) for channel creation. METHODS:Retrospective chart review of 531 pati...

journal_title：Acta ophthalmologica

authors： Coskunseven E,Kymionis GD,Tsiklis NS,Atun S,Arslan E,Siganos CS,Jankov M,Pallikaris IG

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:  To determine the effect of pars plana vitrectomy (PPV) on oxygen saturation in retinal vessels. METHODS:  We performed a prospective consecutive interventional case series of 20 eyes of 20 patients with macular hole or epiretinal membrane. We performed automatic retinal oximetry (Oxymap Inc., Reykjavik, Icel...

journal_title：Acta ophthalmologica

authors： Sín M,Sínová I,Chrapek O,Prachařová Z,Karhanová M,Langová K,Rehák J

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643). METHODS:Twenty-four rabbits ...

journal_title：Acta ophthalmologica

authors： Schultheiss M,Schnichels S,Konrad EM,Bartz-Schmidt KU,Zahn G,Caldirola P,Fsadni MG,Caram-Lelham N,Spitzer MS

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To study anisometropia of spherical equivalent and astigmatism from the onset of myopia at school age to adulthood. METHODS:A total of 240 myopic schoolchildren (mean age 10.9 years), with no previous spectacles, were recruited during 1983-1984 to a randomized 3-year clinical trial of bifocal treatment of myop...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate changes in the anterior chamber depth (ACD) in primary open-angle glaucoma (POAG) patients during latanoprost therapy. METHODS:We carried out a prospective study in which we enrolled 66 newly diagnosed POAG patients treated with latanoprost 0.005% (group 1) and 50 ocular h...

journal_title：Acta ophthalmologica

authors： Cankaya AB,Teberik P,Acaroglu G

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To determine the spectrum of BEST1 mutations and to study the phenotype in Slovenian families with Best vitelliform macular dystrophy (BVMD) to identify genotype-phenotype correlations. METHODS:Twenty patients from five families underwent the ophthalmological examination including electrooculogram (EOG; N = 17...

journal_title：Acta ophthalmologica

authors： Glavač D,Jarc-Vidmar M,Vrabec K,Ravnik-Glavač M,Fakin A,Hawlina M

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To investigate and analyse one hundred-year-old endothelial cells of human transplanted corneal grafts and compare them with intact endothelium of unoperated eyes. SUBJECTS AND METHODS:Specular microscopy was performed on seven individuals (14 eyes) aged >100 years and on seven transplanted corneas with endoth...

journal_title：Acta ophthalmologica

authors： Ruusuvaara P,Vesti E,Koskela E,Setälä K

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

journal_title：Acta ophthalmologica

authors： van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To investigate serial changes in the bleb wall using anterior segment optical coherence tomography (AS-OCT) in patients who had undergone Ahmed glaucoma valve (AGV) implantation. METHODS:A total of 52 patients who had undergone AGV implantation were enrolled. Reflectivity and mean thickness of the bleb wall we...

journal_title：Acta ophthalmologica

authors： Jung KI,Park H,Jung Y,Park CK

更新日期：2015-06-01 00:00:00