In vivo biometric evaluation of Schlemm's canal with spectral-domain optical coherence tomography in pseuduexfoliation glaucoma.

Abstract:

PURPOSE:To perform in vivo imaging of the Schlemm's canal (SC) with anterior segment spectral-domain optical coherence tomography [AS-spectral-domain (SD)-OCT] and also to measure its biometric parameters including the SC length and SC area in patients with pseudoexfoliation (PEX) glaucoma. METHODS:Forty-one consecutive patients with PEX glaucoma and 41 age- and sex-matched normal subjects were enrolled. All subjects underwent imaging with SD-OCT. The SC length and SC area were examined in the temporal sections and measured with customized software. RESULTS:The percentages of the temporal sections in which SC was observable were similar between the two groups. Mean SC length was found significantly shorter, and mean SC area was found significantly smaller in patients with PEX glaucoma than in controls (p = 0.044 and p = 0.036, respectively). Mean intra-ocular pressure (IOP) values were also similar between two groups. No significant correlations were found between SC measurements and IOP. CONCLUSIONS:Anterior segment spectral-domain optical coherence tomography offers non-invasive, in vivo measurement of the SC, and it could be used for investigating the SC changes in patients with PEX glaucoma.

journal_name

Acta Ophthalmol

journal_title

Acta ophthalmologica

authors

Imamoglu S,Sevim MS,Alpogan O,Ercalik NY,Kumral ET,Pekel G,Bardak H

doi

10.1111/aos.13080

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

e688-e692

issue

8

eissn

1755-375X

issn

1755-3768

journal_volume

94

pub_type

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