Abstract:
PURPOSE:To determine the relationships among retinal/choroidal thickness, retinal microvascular network and visual field in high myopia. METHODS:This cross-sectional study included a total of 62 subjects, comprising 31 eyes with high myopia and 31 eyes with emmetropia or low myopia. Optical coherence tomography was used to quantify the thickness of ganglion cell complex (GCC), inner nuclear layer and outer plexiform layer (INOPL), outer retinal layer (ORL) and choroid layer (ChL). Optical coherence tomography angiography was used to quantify the superficial vessel density (SVD) and deep vessel density (DVD). Retinal light sensitivity (RLS) was measured by microperimetry-1 (MP1). The inner ring (1-1.75 mm), the outer ring (1.75-2.5 mm) and the whole ring (1-2.5 mm) around the macula were analysed and compared between the two groups. Pearson correlation analysis was performed to analyse the relationship among them. RESULTS:In the highly myopic group, the thinning of retinal/choroidal thickness and the decrease in retinal vessel density and RLS were found when compared to the emmetropia or low myopia (p < 0.05). Decreased RLS was correlated with decreased ORL thickness (r = -0.469, p = 0.008) and choroid thickness (r = 0.398, p = 0.030). There was no correlation between retinal microvascular network parameters and RLS (p > 0.05), but DVD showed a negative correlation with ORL (r = -0.474, p = 0.007). CONCLUSION:Early visual field defects in highly myopic eyes may be influenced by the ORL loss and defect of choroidal circulation. The deep retinal microvascular network may have a compensatory action in the hypoxic setting of high myopia.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Wu Q,Chen Q,Lin B,Huang S,Wang Y,Zhang L,Lin H,Wang J,Lu F,Shen Mdoi
10.1111/aos.14372subject
Has Abstractpub_date
2020-09-01 00:00:00pages
e709-e714issue
6eissn
1755-375Xissn
1755-3768journal_volume
98pub_type
杂志文章abstract:PURPOSE:To assess the surgical and functional outcome of internal direct cyclopexy as therapy of complicated traumatic cyclodialysis. METHODS:The single-centre interventional case-series study included eyes with traumatic cyclodialysis who had consecutively been treated. Internal cyclopexy was performed using double-a...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
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journal_title:Acta ophthalmologica
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1755-3768.2009.01679.x
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:Acta ophthalmologica
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doi:10.1111/j.1755-3768.2012.02449.x
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journal_title:Acta ophthalmologica
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doi:10.1111/j.1755-3768.2009.01650.x
更新日期:2011-03-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 临床试验,杂志文章
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更新日期:2011-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2021-01-09 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1600-0420.2007.01118.x
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更新日期:2017-06-01 00:00:00