Abstract:
PURPOSE:To assess the retinal vessel blood oxygen saturation preoperatively and postoperatively in patients with different grades of cataracts. METHODS:This study included 40 eyes from 40 patients with senile cataracts ranging from grade 1 to 3. All 40 eyes received standard phacoemulsification and intraocular lens implantation. The mean retinal arterial and venular oxygen saturation (SO2 ) levels were measured using the Oxymap system prior to, immediately after and 3 months after cataract surgery. The arterial-venular difference (AVD) was calculated as the difference between the arterial and venular saturations. Linear regression analysis was performed to identify the relationship between the lens density grades and changes in the measured retina vessel SO2 . RESULTS:The mean age of the subjects was 64.1 ± 7.8 years, and 14 (35%) were male. The mean SO2 level increased in the retinal arterioles from 90.5 ± 7.8% to 95.0 ± 6.7% immediately postoperatively and to 98.3 ± 5.3% at 3 months after surgery (p < 0.001). The mean venular saturation levels were 43.4 ± 9.7%, 58.0 ± 8.5% and 61.9 ± 6.5% at baseline, immediately after and at 3 months postoperatively, respectively, with a statistically significant increase after surgery (p < 0.001). The mean AVD significantly decreased from 47.1 ± 8.9% before surgery to 37.1 ± 7.3% immediately after and 36.4 ± 6.4% 3 months after surgery (p < 0.02). A linear regression model indicated that denser lens opacity was significantly associated with a larger amplitude of the venular SO2 level and the AVD after cataract surgery: change of venous SO2 = 5.934-0.191 × Age + 13.534 × Lens Grade (age: p = 0.586; lens grade: p < 0.001); change in AVD = -7.438-0.037 × Age + 7.744 × Lens Grade (age: p = 0.917; lens grade: p = 0.031). CONCLUSIONS:Retinal arterial and venular oxygen saturation levels are significantly increased after cataract surgery, and increase rates vary with the preoperative grading of lens density.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Chen H,Lin H,Chen W,Zhang B,Xiang W,Gao Q,Chen W,Liu Ydoi
10.1111/aos.13332subject
Has Abstractpub_date
2017-09-01 00:00:00pages
e436-e442issue
6eissn
1755-375Xissn
1755-3768journal_volume
95pub_type
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