Dexamethasone implant with fixed or individualized regimen in the treatment of diabetic macular oedema: six-month outcomes of the UDBASA study.

abstract：PURPOSE:To characterize frequency, morphological cause and time-dependent change of boundary line artefacts in optical coherence tomography (OCT) examinations of centre-involved diabetic macular oedema (ciDME) patients who underwent ranibizumab treatment with 1-year follow-up and to evaluate the impact of artefacts on ...

journal_title：Acta ophthalmologica

authors： Hodzic-Hadzibegovic D,Sander BA,Lund-Andersen H

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:To investigate the presence and distribution of l-kynurenine aminotransferases immunoreactivity in human and animal lenses during cataract formation. METHODS:Immunohistochemistry was conducted using polyclonal antibodies against KAT I, KAT II and KAT III on sections of 26 anterior capsules from patients underg...

journal_title：Acta ophthalmologica

authors： Rejdak R,Oleszczuk A,Rummelt C,Turski WA,Choragiewicz T,Nowomiejska K,Ksiazek K,Thaler S,Zarnowski T,Okuno E,Grieb P,Zrenner E,Kruse F,Junemann AG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To report the 12 months efficacy of initial intravitreal bevacizumab or intravitreal recombinant tissue plasminogen activator (rtPA) combined with expansile gas in patients with subretinal haemorrhage caused by neovascular age-related macular degeneration (AMD). METHODS:Forty-five eyes of 45 patients with subr...

journal_title：Acta ophthalmologica

authors： Mayer WJ,Hakim I,Haritoglou C,Gandorfer A,Ulbig M,Kampik A,Wolf A

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

journal_title：Acta ophthalmologica

authors： Kang P,McAlinden C,Wildsoet CF

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Primary open-angle glaucoma (POAG) is the main cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their regulators (TIMPs and ILs) have been extensively studied as POAG risk factors. Recent reports have showed several single-nucleotide polymorphisms (SNPs) for MMPs, TIMPs and ILs...

journal_title：Acta ophthalmologica

authors： Markiewicz L,Majsterek I,Przybylowska K,Dziki L,Waszczyk M,Gacek M,Kaminska A,Szaflik J,Szaflik JP

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To compare the effectiveness of intravitreal conbercept and ranibizumab treatment for retinopathy of prematurity (ROP). METHODS:In this retrospective study, the date of patients with ROP treated with intravitreal conbercept or ranibizumab from July 2012 to March 2018 with at least 12 months of follow-up at the...

journal_title：Acta ophthalmologica

authors： Cheng Y,Zhu X,Linghu D,Liang J

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:The clinical use and comparison of two recently developed A-scan ultrasound devices. METHODS:The same investigator determined central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) with an OcuScan RxP (Alcon, Forth Worth, Texas, USA) and an AL-2000 (Tomey, Erlangen, Germany) ultras...

journal_title：Acta ophthalmologica

authors： Sohajda Z,Papp J,Berta A,Módis L

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:To evaluate the changes of vascular endothelial growth factor (VEGF) plasma levels after intravitreal injections of ranibizumab or bevacizumab in patients with exudative age-related macular degeneration (AMD). METHODS:Forty-three patients with exudative AMD and 19 age- and sex-matched control patients without ...

journal_title：Acta ophthalmologica

authors： Carneiro AM,Costa R,Falcão MS,Barthelmes D,Mendonça LS,Fonseca SL,Gonçalves R,Gonçalves C,Falcão-Reis FM,Soares R

更新日期：2012-02-01 00:00:00

abstract：:Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...

journal_title：Acta ophthalmologica

authors： Kaplowitz K,Kuei A,Klenofsky B,Abazari A,Honkanen R

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To assess the postoperative stability of three-piece intraocular lens (IOL) implants using ultrasound biomicroscopy (UBM). METHODS:This is a prospective observational cohort case series. Best-corrected visual acuity (BCVA) assessment, slit lamp examination, refraction and UBM evaluation were performed preopera...

journal_title：Acta ophthalmologica

authors： Ang GS,Duncan L,Atta HR

更新日期：2012-03-01 00:00:00

abstract：PURPOSE: This study aimed to compare scanning laser polarimetry measurements of retinal nerve fibre layer (RNFL) thickness in eyes of migraine patients with those in eyes of age-matched, healthy subjects. METHODS: The study was designed as an observational, prospective, cross-sectional study. It included 57 eyes of 57...

journal_title：Acta ophthalmologica

authors： Martinez A,Proupim N,Sanchez M

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To investigate long-term visual results of treatment with anti-vascular endothelial growth factor (VEGF) agents for neovascular age-related macular degeneration (nAMD) following a treat-and-extend regimen. METHODS:Retrospective review of 155 patients who initiated treatment with bevacizumab for nAMD in one eye...

journal_title：Acta ophthalmologica

authors： Berg K,Roald AB,Navaratnam J,Bragadóttir R

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Complex segregation analysis of 60 unrelated sporadic keratoconus (KC) families was performed to reveal the presumed mode of inheritance in our dataset. METHODS:Sixty probands, 212 family members and 212 age and gender matched healthy controls underwent clinical and videokeratographic examination. Family aggre...

journal_title：Acta ophthalmologica

authors： Kriszt A,Losonczy G,Berta A,Vereb G,Takács L

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To determine the molecular genetic cause in previously unreported probands with optic atrophy from the United Kingdom, Czech Republic and Canada. METHODS:OPA1 coding regions and flanking intronic sequences were screened by direct sequencing in 82 probands referred with a diagnosis of bilateral optic atrophy. D...

journal_title：Acta ophthalmologica

authors： Liskova P,Tesarova M,Dudakova L,Svecova S,Kolarova H,Honzik T,Seto S,Votruba M

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To evaluate the association between the macular structure on spectral-domain optical coherence tomography (SD-CT) and visual outcome after vitrectomy for lamellar macular hole (LMH). METHODS:Best-corrected visual acuity (VA) and SD-OCT images of the macula were assessed before and after surgery in 30 eyes of 3...

journal_title：Acta ophthalmologica

authors： Lee CS,Koh HJ,Lim HT,Lee KS,Lee SC

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To investigate the distribution of intraocular pressure (IOP) measured by Goldmann applanation tonometry (GAT) and factors correlating with IOP, with special attention to age, in a large sample of ophthalmologically normal Japanese subjects. METHODS:A total of 7313 subjects (2847 male, 4466 female) were select...

journal_title：Acta ophthalmologica

authors： Fukuoka S,Aihara M,Iwase A,Araie M

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...

journal_title：Acta ophthalmologica

authors： Yuki K,Murat D,Kimura I,Tsubota K

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland. METHODS:We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case historie...

journal_title：Acta ophthalmologica

authors： Baldursdóttir E,Sigurdsson H,Jónasson L,Gottfredsson M

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To compare the outcomes of microcatheter-assisted circumferential trabeculotomy to standard rigid probe trabeculotomy in childhood glaucomas. METHODS:Eyes of children requiring trabeculotomy for primary congenital or secondary paediatric glaucoma were randomized to undergo either trabeculotomy using the Glauco...

journal_title：Acta ophthalmologica

authors： El Sayed Y,Gawdat G

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Galectin-1 regulates endothelial cell function and promotes angiogenesis. We investigated the hypothesis that galectin-1 may be involved in the pathogenesis of proliferative diabetic retinopathy (PDR). METHODS:Vitreous samples from 36 PDR and 20 nondiabetic patients, epiretinal fibrovascular membranes from 13 ...

journal_title：Acta ophthalmologica

authors： Abu El-Asrar AM,Ahmad A,Allegaert E,Siddiquei MM,Alam K,Gikandi PW,De Hertogh G,Opdenakker G

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To describe the clinical phenotype and the molecular pathology in a group of patients with congenital stationary night blindness due to mutations in GRM6, a gene encoding the ON bipolar metabotropic glutamate receptor 6 (mGluR6). METHODS:Nine patients from seven families (age range, 7-75; median, 10 years) wit...

journal_title：Acta ophthalmologica

authors： Sergouniotis PI,Robson AG,Li Z,Devery S,Holder GE,Moore AT,Webster AR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Retinal Vessel Analyser (RVA) is a validated instrument to measure retinal vessel diameter in humans. The purpose of this study was to assess the reproducibility (inter-observer reliability) and the repeatability (test-retest reliability) of RVA with a microscope-mounted fundus camera to determine retinal vesse...

journal_title：Acta ophthalmologica

authors： Papadopoulou DN,Mangioris G,Petropoulos IK,Mendrinos E,Mavropoulos A,Pournaras CJ

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To study the connection between parental myopia and their children's myopia from school age to adulthood. METHODS:Two hundred and forty myopic schoolchildren (119 boys, 121 girls, mean age 10.9 years) with no previous spectacles for myopia were recruited to a 3-year treatment trial with different use of specta...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:We present a genetic and clinical analysis of two sisters, 3 and 4 years of age, with nanophthalmos and macular folds. METHODS:Ophthalmological examination, general paediatric examination and molecular genetic analysis of the MFRP gene were performed in both affected siblings. RESULTS:Clinical analysis showed...

journal_title：Acta ophthalmologica

authors： Wasmann RA,Wassink-Ruiter JS,Sundin OH,Morales E,Verheij JB,Pott JW

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To indirectly measure stromal riboflavin penetration using commercially available riboflavin solutions and new and existing epithelium-off, trans-epithelial and iontophoresis-assisted delivery protocols. METHODS:Forty porcine eyes were divided into eight groups. Group 1: Ricrolin applied to the de-epithelialis...

journal_title：Acta ophthalmologica

authors： Hayes S,Morgan SR,O'Brart DP,O'Brart N,Meek KM

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To investigate the intravitreal levels of potent vasoactive, angiogenic and extracellular matrix remodelling factors in the diabetic patients with simvastatin treatment. METHODS:This is an institutional, prospective, observational case-control study. Type-1 and type-2 diabetic patients on lipophilic simvastati...

journal_title：Acta ophthalmologica

authors： Tuuminen R,Sahanne S,Loukovaara S

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:  To evaluate central corneal thickness (CCT), intraocular pressure (IOP) and eye refraction in patients with congenital growth hormone (GH) deficiency. METHODS:Retrospective case series. Forty-five patients with growth defect treated with recombinant GH and 45 healthy children underwent ophthalmological exami...

journal_title：Acta ophthalmologica

authors： Parentin F,Pensiero S

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS:This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a ran...

journal_title：Acta ophthalmologica

authors： Rim TH,Han J,Choi YS,Lee T,Kim SS

更新日期：2017-11-01 00:00:00