Abstract:
:Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation have already begun by the time tractional forces lead to a change for the worse. Vitreomacular traction alone is perhaps not able to induce AMD. It would seem sensible to consider vitreous changes when diagnosing and treating AMD patients because of the high coincidence of vitreomacular traction and choroidal neovascularization (CNV) and the often successful treatment of other diseases of the vitreoretinal interface by vitrectomy. The concept of the pathogenesis of AMD should therefore be extended to include the influence of the vitreous, especially where therapeutic concepts such as pharmacological vitreolysis and vitreous separation have been established as causative treatment of late forms of AMD.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Schulze S,Hoerle S,Mennel S,Kroll Pdoi
10.1111/j.1755-3768.2008.01210.xsubject
Has Abstractpub_date
2008-08-01 00:00:00pages
470-81issue
5eissn
1755-375Xissn
1755-3768pii
AOS1210journal_volume
86pub_type
杂志文章,评审abstract:PURPOSE:To determine the relationships among retinal/choroidal thickness, retinal microvascular network and visual field in high myopia. METHODS:This cross-sectional study included a total of 62 subjects, comprising 31 eyes with high myopia and 31 eyes with emmetropia or low myopia. Optical coherence tomography was us...
journal_title:Acta ophthalmologica
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journal_title:Acta ophthalmologica
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更新日期:2017-11-01 00:00:00
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更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-01-24 00:00:00
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更新日期:2016-05-01 00:00:00
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journal_title:Acta ophthalmologica
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更新日期:2013-06-01 00:00:00
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更新日期:2014-08-01 00:00:00
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journal_title:Acta ophthalmologica
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更新日期:2013-02-01 00:00:00
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更新日期:2014-11-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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更新日期:2009-02-01 00:00:00
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更新日期:2015-06-01 00:00:00
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更新日期:2011-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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更新日期:2017-05-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
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更新日期:2010-11-01 00:00:00
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2018-11-01 00:00:00
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更新日期:2020-11-16 00:00:00
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更新日期:2013-03-01 00:00:00