Topical dexamethasone-cyclodextrin nanoparticle eye drops for non-infectious Uveitic macular oedema and vitritis - a pilot study.

abstract：PURPOSE:To assess thickness and associations of the peripapillary choroidal layers. METHODS:The population-based Beijing Eye Study included 3468 participants with an age of 50+ years. Using spectral-domain optical coherence tomography, we measured the large vessel layer (LVL) and small-to-medium vessel layer (SMVL) of...

journal_title：Acta ophthalmologica

authors： Xu J,Wang YX,Jiang R,Wei WB,Xu L,Jonas JB

更新日期：2017-09-01 00:00:00

abstract：AIMS:This prospective, multicenter, single-masked study evaluated the additive effect of dorzolamide hydrochloride 2% on the diurnal intraocular pressure (IOP) curve and retinal and retrobulbar hemodynamics in patients with primary open-angle glaucoma (POAG) treated with morning-dosed bimatoprost 0.03%. METHODS:Eighty...

journal_title：Acta ophthalmologica

authors： Stankiewicz A,Misiuk-Hojło M,Grabska-Liberek I,Romanowska-Dixon B,Wierzbowska J,Wasyluk J,Mulak M,Szuścik I,Sierdziński J,Ehrlich R,Siesky B,Harris A

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...

journal_title：Acta ophthalmologica

authors： Bonnin P,Pournaras JA,Lazrak Z,Cohen SY,Legargasson JF,Gaudric A,Levy BI,Massin P

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma naïve of previous filtering surgery. METHODS:Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with op...

journal_title：Acta ophthalmologica

authors： Aptel F,Denis P,Rouland JF,Renard JP,Bron A

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Tissue inhibitor of metalloproteinase (TIMP) is known to play a role in age-related macular degeneration (AMD). We wished to investigate alterations in different late stages of AMD: neovascular AMD and geographic atrophy (GA). METHODS:This was a prospective case-control study. A total of 125 participants were ...

journal_title：Acta ophthalmologica

authors： Krogh Nielsen M,Subhi Y,Rue Molbech C,Nilsson LL,Nissen MH,Sørensen TL

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:Diabetic retinopathy is diagnosed by fundus photography and optical coherence tomography (OCT) scanning. However, adaptive optics (AO) imaging can be expected to add new aspects to the knowledge of diabetic retinopathy because photographic resolution is improved by reducing the influence of optical aberrations ...

journal_title：Acta ophthalmologica

authors： Bek T

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS). METHODS:The wireless CLS is a disposable silicone soft contact lens with a sensor embedded in it, allowing the wireless me...

journal_title：Acta ophthalmologica

authors： Leonardi M,Pitchon EM,Bertsch A,Renaud P,Mermoud A

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To explore associations of lamina cribrosa thickness with axial length and thickness of the posterior sclera in monkeys. METHODS:Examining histological sections by light microscopy, we measured the thickness of the lamina cribrosa and posterior sclera and axial length. RESULTS:The study included 28 animals (2...

journal_title：Acta ophthalmologica

authors： Jonas JB,Kutscher JN,Panda-Jonas S,Hayreh SS

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To evaluate the potential use of decellularized porcine stromal matrix (PSM) for reconstruction of corneal stroma in a rabbit model. METHODS:Ten chinchilla bastard rabbit corneas were exposed to a circular half-thickness keratotomy with a 3.0 mm diameter at the central cornea. Porcine corneas were decellulariz...

journal_title：Acta ophthalmologica

authors： Yoeruek E,Bayyoud T,Maurus C,Hofmann J,Spitzer MS,Bartz-Schmidt KU,Szurman P

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Choroideremia is a currently incurable X-linked recessive retinal degeneration that leads to blindness. Gene therapy approaches to date target the outer retinal layers. However, the choroideremia (CHM) gene is expressed in all retinal layers, and a previous study on a small cohort of choroideremia patients sugg...

journal_title：Acta ophthalmologica

authors： Fu DJ,Xue K,Jolly JK,MacLaren RE

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To compare structural and functional improvements in patients with vitreous haemorrhage (VH) with different IOPs re-established at the end of pars plana vitrectomy (PPV). METHODS:It is a prospective, randomized, comparative, interventional study. Ninety-five patients with nonclearing VH were randomized to rece...

journal_title：Acta ophthalmologica

authors： Zhou C,Zhang Z,Luo D,Gu C,Lahm T,Draga D,Qiu Q

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To determine alterations in the retina of patients with Alzheimer's disease (AD) by the newly developed technique of fluorescence lifetime imaging ophthalmoscopy (FLIO) in a pilot study. METHODS:FLIO set-up uses a scanning laser ophthalmoscope (HRA2, Heidelberg Engineering, Germany), which was modified by the ...

journal_title：Acta ophthalmologica

authors： Jentsch S,Schweitzer D,Schmidtke KU,Peters S,Dawczynski J,Bär KJ,Hammer M

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate changes in the anterior chamber depth (ACD) in primary open-angle glaucoma (POAG) patients during latanoprost therapy. METHODS:We carried out a prospective study in which we enrolled 66 newly diagnosed POAG patients treated with latanoprost 0.005% (group 1) and 50 ocular h...

journal_title：Acta ophthalmologica

authors： Cankaya AB,Teberik P,Acaroglu G

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

journal_title：Acta ophthalmologica

authors： van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To examine the influence of light source on letter contrast sensitivity in subjects with age-related macular degeneration (AMD). METHODS:Halogen incandescent bulbs and low-energy fluorescent tubes were tested with 70 subjects with AMD. The subjects' contrast sensitivity was determined in a randomized single-bl...

journal_title：Acta ophthalmologica

authors： Holton H,Christiansen AB,Albeck MJ,Johnsen CR

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To evaluate the EyeSi(™) simulator in regard to assessing competence in cataract surgery. The primary objective was to explore all simulator metrics to establish a proficiency-based test with solid evidence. The secondary objective was to evaluate whether the skill assessment was specific to cataract surgery. ...

journal_title：Acta ophthalmologica

authors： Thomsen AS,Kiilgaard JF,Kjaerbo H,la Cour M,Konge L

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To examine retinal vascular changes in the peripapillary and macular areas in patients with pituitary adenoma (PA) using optical coherence tomography angiography (OCTA). METHODS:Cross-sectional, retrospective study of 17 consecutive PA patients and 16 healthy subjects. All patients underwent a neuro-ophthalmol...

journal_title：Acta ophthalmologica

authors： Dallorto L,Lavia C,Jeannerot AL,Shor N,Jublanc C,Boch AL,Bodaghi B,Tadayoni R,Touitou V,Bonnin S

更新日期：2019-12-06 00:00:00

abstract：PURPOSE:We aimed to evaluate the effectiveness of bicanalicular double silicone intubation in dacryocystorhinostomy (DCR) and canaliculoplasty for distal or common canalicular obstruction. METHODS:We reviewed the medical records of patients with distal or common canalicular obstruction who had undergone bicanalicular ...

journal_title：Acta ophthalmologica

authors： Hwang SW,Khwarg SI,Kim JH,Choung HK,Kim NJ

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:To compare changes in macular pigment optical density (MPOD) and serum lutein concentration between free lutein and lutein esters supplements in healthy Japanese individuals. METHODS:Twenty healthy subjects (age range, 22-47 years) were recruited into this prospective, randomized, doubled-blind comparative stu...

journal_title：Acta ophthalmologica

authors： Yoshizako H,Hara K,Takai Y,Kaidzu S,Obana A,Ohira A

更新日期：2016-09-01 00:00:00

abstract：:Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...

journal_title：Acta ophthalmologica

authors： Kaplowitz K,Kuei A,Klenofsky B,Abazari A,Honkanen R

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To investigate the clinical efficacy and safety of an additional core vitrectomy to the standard therapy in patients with exudative age-related macular degeneration (ARMD). METHODS:In this prospective, controlled, single-centre study, 50 eyes of 50 patients (mean age: 74.1 ± 7.1; median 74 (69/78)) with ARMD w...

journal_title：Acta ophthalmologica

authors： Schramm K,Mueller M,Koch FH,Singh P,Kohnen T,Koss MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...

journal_title：Acta ophthalmologica

authors： Prokosch V,Brockhaus K,Anders F,Liu H,Mercieca K,Gericke A,Melkonyan H,Thanos S

更新日期：2019-12-29 00:00:00

abstract：PURPOSE:We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS:Thirty-seven 3-8 years old c...

journal_title：Acta ophthalmologica

authors： Stoica F,Chirita-Emandi A,Andreescu N,Stanciu A,Zimbru CG,Puiu M

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

journal_title：Acta ophthalmologica

authors： Kang P,McAlinden C,Wildsoet CF

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Primary open-angle glaucoma (POAG) is the main cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their regulators (TIMPs and ILs) have been extensively studied as POAG risk factors. Recent reports have showed several single-nucleotide polymorphisms (SNPs) for MMPs, TIMPs and ILs...

journal_title：Acta ophthalmologica

authors： Markiewicz L,Majsterek I,Przybylowska K,Dziki L,Waszczyk M,Gacek M,Kaminska A,Szaflik J,Szaflik JP

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:Photodynamic riboflavin/ultraviolet-A (UVA)-induced collagen cross-linking, which increases the biomechanical stiffness of the human cornea by about 300%, has been introduced recently as a possible treatment for progressive keratoconus. The present study was undertaken to evaluate the longterm biomechanical eff...

journal_title：Acta ophthalmologica

authors： Wollensak G,Iomdina E

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:To investigate flow area changes measured using optical coherence tomography angiography (OCTA; RTVue XR Avanti® ) in patients with retinitis pigmentosa (RP) with preserved visual acuity (VA). METHODS:This was an age- and refraction-matched case-control study. Consecutive patients with a best-corrected visual ...

journal_title：Acta ophthalmologica

authors： Takagi S,Hirami Y,Takahashi M,Fujihara M,Mandai M,Miyakoshi C,Tomita G,Kurimoto Y

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...

journal_title：Acta ophthalmologica

authors： Tassignon MJ,Bartholomeeusen E,Rozema JJ,Jongenelen S,Mathysen DG

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:Central retinal vein occlusion (CRVO) entails retinal hypoxia that often causes visual impairment. It has been shown that oxygen saturation in larger retinal vessels correlates with the visual acuity at the time of diagnosis of CRVO but has no predictive value for the visual outcome in patients treated with ant...

journal_title：Acta ophthalmologica

authors： Krejberg Jeppesen S,Sín M,Hakon Hardarson S,Bek T

更新日期：2021-01-09 00:00:00