One hundred-year-old human corneal and transplanted corneal graft endothelium.

abstract：PURPOSE:To evaluate association of the van Herick (VH) grades with the ultrasound biomicroscopic (UBM) parameters, appositional irido-trabecular contact (A-ITC) and plateau iris (PI) in a randomly sampled population. METHODS:A 10% random sample of all residents aged 40 or older of the Kumejima study underwent UBM unde...

journal_title：Acta ophthalmologica

authors： Uejyo C,Henzan IM,Nakamura Y,Ishikawa S,Sakai H,Sawaguchi S,Kumar RS,Iwase A,Tomidokoro A,Araie M

更新日期：2020-06-22 00:00:00

abstract：PURPOSE:To evaluate the biomechanical properties of the cornea using Corneal Visualization Scheimpflug Technology (CorVis ST, Oculus) in eyes with primary open-angle glaucoma (POAG) and normal control eyes. METHODS:A comparative cross-sectional study that included 42 patients with POAG and 60 normal control subjects m...

journal_title：Acta ophthalmologica

authors： Tian L,Wang D,Wu Y,Meng X,Chen B,Ge M,Huang Y

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Central retinal vein occlusion (CRVO) entails retinal hypoxia that often causes visual impairment. It has been shown that oxygen saturation in larger retinal vessels correlates with the visual acuity at the time of diagnosis of CRVO but has no predictive value for the visual outcome in patients treated with ant...

journal_title：Acta ophthalmologica

authors： Krejberg Jeppesen S,Sín M,Hakon Hardarson S,Bek T

更新日期：2021-01-09 00:00:00

abstract：PURPOSE:To evaluate the safety and efficacy of 1.5% dexamethasone nanoparticle (DexNP) drops in eyes with non-infectious uveitic macular oedema and vitritis. METHODS:In a prospective pilot study, DexNP drops were administered four times a day for 4 weeks followed by drops tapering over a period of another 4 weeks. Fol...

journal_title：Acta ophthalmologica

authors： Shulman S,Jóhannesson G,Stefánsson E,Loewenstein A,Rosenblatt A,Habot-Wilner Z

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Pathological alterations within optic nerve axons and progressive loss of the parental retinal ganglion cell (RGC) bodies are characteristics of glaucomatous neuropathy. Abnormally elevated intraocular pressure (IOP) is thought to be the major risk factor for most forms of glaucomatous changes, while lowering o...

journal_title：Acta ophthalmologica

authors： Prokosch V,Brockhaus K,Anders F,Liu H,Mercieca K,Gericke A,Melkonyan H,Thanos S

更新日期：2019-12-29 00:00:00

abstract：PURPOSE:To report complications after the implantation of intrastromal corneal ring segments (Keraring; Mediphacos, Belo Horizonte, Brazil) in keratoconic eyes using a femtosecond laser (IntraLase; Advanced Medical Optics, Santa Ana, California, USA) for channel creation. METHODS:Retrospective chart review of 531 pati...

journal_title：Acta ophthalmologica

authors： Coskunseven E,Kymionis GD,Tsiklis NS,Atun S,Arslan E,Siganos CS,Jankov M,Pallikaris IG

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:Assessment on enucleated pig eyes of a novel and minimally invasive method for the continuous monitoring of intraocular pressure (IOP), based on a novel wireless contact lens sensor (CLS). METHODS:The wireless CLS is a disposable silicone soft contact lens with a sensor embedded in it, allowing the wireless me...

journal_title：Acta ophthalmologica

authors： Leonardi M,Pitchon EM,Bertsch A,Renaud P,Mermoud A

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643). METHODS:Twenty-four rabbits ...

journal_title：Acta ophthalmologica

authors： Schultheiss M,Schnichels S,Konrad EM,Bartz-Schmidt KU,Zahn G,Caldirola P,Fsadni MG,Caram-Lelham N,Spitzer MS

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To report the functional and anatomical outcomes resulting from the use of intravitreal pegaptanib sodium (Macugen) in patients with diabetic macular oedema (DMO). METHODS:We conducted a retrospective outcome analysis, by optical coherence tomography (OCT) and best-corrected visual acuity (BCVA), of eyes with ...

journal_title：Acta ophthalmologica

authors： Querques G,Bux AV,Martinelli D,Iaculli C,Noci ND

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:Metrics that capture changes in the retinal microvascular structure are relevant in the context of cardiometabolic disease development. The microvascular topology is typically quantified using monofractals, although it obeys more complex multifractal rules. We study mono- and multifractals of the retinal microv...

journal_title：Acta ophthalmologica

authors： Van Craenendonck T,Gerrits N,Buelens B,Petropoulos IN,Shuaib A,Standaert A,Malik RA,De Boever P

更新日期：2020-09-16 00:00:00

abstract：PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...

journal_title：Acta ophthalmologica

authors： Tassignon MJ,Bartholomeeusen E,Rozema JJ,Jongenelen S,Mathysen DG

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:  To evaluate central corneal thickness (CCT), intraocular pressure (IOP) and eye refraction in patients with congenital growth hormone (GH) deficiency. METHODS:Retrospective case series. Forty-five patients with growth defect treated with recombinant GH and 45 healthy children underwent ophthalmological exami...

journal_title：Acta ophthalmologica

authors： Parentin F,Pensiero S

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To assess the surgical and functional outcome of internal direct cyclopexy as therapy of complicated traumatic cyclodialysis. METHODS:The single-centre interventional case-series study included eyes with traumatic cyclodialysis who had consecutively been treated. Internal cyclopexy was performed using double-a...

journal_title：Acta ophthalmologica

authors： Wang C,Peng XY,You QS,Liu Y,Pang XQ,Zheng PF,Jonas JB

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:The cyclolignan picropodophyllin (PPP) efficiently blocks the activity of insulin-like growth factor-1 receptor (IGF-1R) and inhibits growth of uveal melanoma cells in vitro and in vivo. In this study, we aimed to investigate the efficiency of orally administered PPP on growth of uveal melanoma xenografts. Furt...

journal_title：Acta ophthalmologica

authors： Economou MA,Andersson S,Vasilcanu D,All-Ericsson C,Menu E,Girnita A,Girnita L,Axelson M,Seregard S,Larsson O

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

journal_title：Acta ophthalmologica

authors： van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Monthly dosing with ranibizumab (RBZ) is needed to achieve maximal visual gains in patients with neovascular ('wet') age-related macular degeneration (wAMD). In Sweden, dosing is performed as needed (RBZ PRN), resulting in suboptimal efficacy. Intravitreal aflibercept (IVT-AFL) every 2 months after three initia...

journal_title：Acta ophthalmologica

authors： Panchmatia HR,Clements KM,Hulbert E,Eriksson M,Wittrup-Jensen K,Nilsson J,Weinstein MC

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to analyse 69 Chinese patients with USH2A mutations and to assess the genotype-phenotype correlation. METHODS:All 36 Usher syndrome type IIA patients and 33 nonsyndromic RP (retinitis pigmentosa) patients underwent clinical examinations. Eye examinations included best-corrected visual...

journal_title：Acta ophthalmologica

authors： Meng X,Liu X,Li Y,Guo T,Yang L

更新日期：2020-10-29 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma naïve of previous filtering surgery. METHODS:Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with op...

journal_title：Acta ophthalmologica

authors： Aptel F,Denis P,Rouland JF,Renard JP,Bron A

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To examine the movement of air injected in the cornea in simulated deep anterior lamellar keratoplasty (DALK), from the needle tip to the formation of different types of big bubbles (BB) and to ascertain how air travels through the stroma and pre-Descemet's layer [Dua's layer (PDL)] to create a type-1 (air betw...

journal_title：Acta ophthalmologica

authors： Dua HS,Faraj LA,Kenawy MB,AlTaan S,Elalfy MS,Katamish T,Said DG

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland. METHODS:We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case historie...

journal_title：Acta ophthalmologica

authors： Baldursdóttir E,Sigurdsson H,Jónasson L,Gottfredsson M

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To study anisometropia of spherical equivalent and astigmatism from the onset of myopia at school age to adulthood. METHODS:A total of 240 myopic schoolchildren (mean age 10.9 years), with no previous spectacles, were recruited during 1983-1984 to a randomized 3-year clinical trial of bifocal treatment of myop...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：:There is still no agreement on total plasma homocysteine (tHcy) role in age-related macular degeneration (AMD), the leading cause of new blindness in industrialized countries. We performed a systematic review and meta-analysis of the published data on the correlation between tHcy and AMD. MEDLINE/PubMed and ISI Web of...

journal_title：Acta ophthalmologica

authors： Pinna A,Zaccheddu F,Boscia F,Carru C,Solinas G

更新日期：2018-05-01 00:00:00

abstract：:Although the work for which Emil von Behring (1854-1917) was awarded the first Nobel Prize Winner for Medicine or Physiology in 1901 was on serum therapy, not only was he trained and worked as an ophthalmologist but he also wrote his doctoral dissertation on a practical ophthalmological topic whilst in Berlin under Ca...

journal_title：Acta ophthalmologica

authors： Grzybowski A,Wilhelm H

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Study purpose was to investigate the effects of bariatric surgery on intraocular pressure (IOP) and other ophthalmic parameters in a prospective observational follow-up study. METHODS:Ophthalmic examination was performed on 22 obese women before and 6 months after bariatric surgery. A control group of 15 non-o...

journal_title：Acta ophthalmologica

authors： Viljanen A,Hannukainen JC,Soinio M,Karlsson HK,Salminen P,Nuutila P,Vesti E

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To examine the prevalence of anisometropia of spherical refraction (AnisoSR), astigmatism (AnisoAST) and spherical equivalent (AnisoSE) and their associations with spherical refraction (SR), refractive astigmatism (AST), spherical equivalent (SE) and interocular differences of ocular biometric parameters among ...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M,Kaprio J,Rantanen T

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To determine alterations in the retina of patients with Alzheimer's disease (AD) by the newly developed technique of fluorescence lifetime imaging ophthalmoscopy (FLIO) in a pilot study. METHODS:FLIO set-up uses a scanning laser ophthalmoscope (HRA2, Heidelberg Engineering, Germany), which was modified by the ...

journal_title：Acta ophthalmologica

authors： Jentsch S,Schweitzer D,Schmidtke KU,Peters S,Dawczynski J,Bär KJ,Hammer M

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:A free autologous retinal pigment epithelium (RPE)-choroid graft can be harvested during transplantation surgery from a 6 or 12 o'clock site in the midperiphery. This study evaluated whether proliferative vitreoretinopathy (PVR) occurs more frequently in patients with an inferior donor site retinotomy, which is...

journal_title：Acta ophthalmologica

authors： van Zeeburg EJ,Maaijwee K,van Meurs JC

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children. SETTING:Ege University Faculty of Medicine, Department of Ophthalmology. METHODS:Pentacam measurements of 50 (23 boys and 27 girls) children...

journal_title：Acta ophthalmologica

authors： Palamar M,Egrilmez S,Uretmen O,Yagci A,Kose S

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:To investigate the ability of mesenchymal stem cells (MSC) to transdifferentiate to corneal epithelial cells in experimental limbal stem cell deficiency in rabbits. METHODS:Total limbal stem cell deficiency was produced in 21 right eyes of 21 New Zealand rabbits; 6 eyes served as controls (group 1, G1). After ...

journal_title：Acta ophthalmologica

authors： Reinshagen H,Auw-Haedrich C,Sorg RV,Boehringer D,Eberwein P,Schwartzkopff J,Sundmacher R,Reinhard T

更新日期：2011-12-01 00:00:00