Abstract:
PURPOSE:The purpose of this study was to investigate the safety and efficacy of phacocanaloplasty with suprachoroidal drainage (PCscD) and to compare its intraocular pressure (IOP)-lowering and drug-sparing effect to canaloplasty with suprachoroidal drainage (CscD). METHODS:The study retrospective interventional study included patients with open-angle glaucoma or secondary forms of glaucoma who underwent either CscD or PCscD between the year 2011 and 2014 in Knappschaft Eye Clinic Sulzbach. Primary end-points were IOP reduction and the number of IOP-lowering medication after 12 months. Secondary end-points were intraoperative and postoperative complications. RESULTS:A total of 328 eyes were included, 193 were treated with CscD and 135 underwent PCscD. Canaloplasty with scD achieved an IOP reduction of 37.0% (from 20.9 ± 3.6 mmHg to 13.2 ± 2.6 mmHg) after 1 year, whereas PCscD showed a significant higher reduction of 47.4% (from 23.2 ± 5.1 mmHg to 12.2 ± 1.7 mmHg). Reduction in IOP-lowering medication was higher after PCscD (from 3.6 ± 0.6 to 0.2 ± 0.5) than after CscD (from 3.5 ± 0.8 to 0.7 ± 1.0). Twelve months after surgery 55.5% in the CscD group and 80.2% in the PCscD group were free of IOP-lowering medication. In both groups, no severe or sight-threatening complications occurred. CONCLUSION:Combining cataract surgery and CscD achieves a higher IOP reduction, and patients postoperatively need less IOP-lowering medication than after CscD alone.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Seuthe AM,Januschowski K,Mariacher S,Ebner M,Opitz N,Szurman P,Boden Kdoi
10.1111/aos.13393subject
Has Abstractpub_date
2018-02-01 00:00:00pages
e74-e78issue
1eissn
1755-375Xissn
1755-3768journal_volume
96pub_type
杂志文章abstract:PURPOSE:Age-related macular degeneration (AMD) is generally considered a disease of the macula. However, recent studies show peripheral retinal lesions are prevalent in patients with AMD, indicative of a disease process that is more widespread. Full-field electroretinography (ffERG) measures an electrical response, not...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14571
更新日期:2020-08-24 00:00:00
abstract:PURPOSE:This study aimed to investigate intraocular pressure (IOP) measurements taken using the dynamic contour tonometer (DCT) and the non-contact tonometer (NCT) in subjects with keratoconus. METHODS:Intraocular pressure was measured in 20 keratoconus subjects and 20 age-matched control subjects using the DCT and NC...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01690.x
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abstract:PURPOSE:To evaluate the incidence of central hole-induced ring-shaped dysphotopsia after posterior chamber phakic implantable collamer lens (ICL) with central hole (hole ICL) implantation and to investigate the causes of central hole-induced dysphotopsia. METHODS:The clinical study enrolled 29 eyes of 15 consecutive m...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13248
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abstract::Ziv-aflibercept (Zaltrap® ), a recombinant fusion protein that binds diffusible vascular endothelial growth factor (VEGF), is approved for the treatment of metastatic colorectal carcinoma. Its molecular structure is the same as aflibercept (Eylea® ), thus making it an attractive option for the off-label treatment of c...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14328
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abstract:PURPOSE:To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS:Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS e...
journal_title:Acta ophthalmologica
pub_type:
doi:10.1111/aos.13950
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To examine visual acuity, refraction and ocular status before, during and after hyperbaric oxygen therapy (HBOT). METHODS:Twenty-nine patients underwent 40 standard protocol HBOT treatments. In all subjects, refraction and best corrected visual acuity were measured at baseline and after ten, 20, 30 and 40 trea...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
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abstract:PURPOSE:To report the prevalence of pseudoexfoliation (PEX) syndrome and glaucoma associated with PEX (PEX-G) and their relating factors of them in a south-western island of Japan. METHODS:A population-based survey of all residents aged ≥ 40 years was conducted in Kumejima, Okinawa, Japan, and 3762 subjects (participa...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14396
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2020-07-23 00:00:00
abstract:PURPOSE:To investigate the clinical features and outcomes of diffuse large B-cell lymphoma (DLBCL) involving the eye and ocular adnexa in an East Asian population and emphasize the importance of prompt biopsy and treatment in unusually progressive ocular adnexal DLBCL for better visual outcomes. METHODS:Retrospective ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14725
更新日期:2021-01-09 00:00:00
abstract::The development of ophthalmology was greatly restricted in Poland in the 19th century, because it was partitioned and occupied by its three dominant neighbours. Polish medical universities were closed, and in Polish hospitals, only clinical work was possible. Those who wanted to study medicine and become ophthalmologi...
journal_title:Acta ophthalmologica
pub_type: 历史文章,杂志文章
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更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To analyse pupil responses to specific chromatic stimuli in patients with advanced retinitis pigmentosa (RP) to ascertain whether chromatic pupillography can be used as an objective marker for residual retinal function. To examine correlations between parameters of the pupil response and the perception threshol...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13259
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:Eyelid sebaceous carcinoma (SC) remains a common diagnostic pitfall for both the clinician and histopathologist. The aim of this study was to describe perforin as a new marker in the immunohistochemistry panel for SC. METHODS:A total of 29 cases were retrieved from the Pathology archives, including 11 sebaceou...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12972
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS:Data from 139 patients with conjunctival mela...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13007
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. METHODS:This was a prospective, observati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12382
更新日期:2014-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14754
更新日期:2021-01-10 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02216.x
更新日期:2012-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12962
更新日期:2016-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13112
更新日期:2016-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13536
更新日期:2018-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02380.x
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643). METHODS:Twenty-four rabbits ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13215
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13502
更新日期:2018-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13956
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To investigate the utility of biomechanical property measurements using a Scheimpflug-based tonometer (SBT) and/or anterior segment optical coherence tomography (AS-OCT) for diagnosing forme fruste keratoconus (FFK). METHODS:In this retrospective interventional case series, 23 eyes with FFK of 23 consecutive p...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14700
更新日期:2020-12-16 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13463
更新日期:2017-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.14078
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To examine the influence of light source on letter contrast sensitivity in subjects with age-related macular degeneration (AMD). METHODS:Halogen incandescent bulbs and low-energy fluorescent tubes were tested with 70 subjects with AMD. The subjects' contrast sensitivity was determined in a randomized single-bl...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1755-3768.2009.01809.x
更新日期:2011-12-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02381.x
更新日期:2013-05-01 00:00:00